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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：O95760 New Search
5PDB entries
7Biological assembly
8chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2KLL Solution structure of human interleukin-33 Deposited 2009-07-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 111–270（160 aa） Fragment：UNP residues 110-270
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；308 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR sample composition 1 mM [U-100% 15N] Interleukin-33, 20 mM sodium phosphate, 100 mM sodium chloride, 5 mM beta-mercaptoethanol, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 1 mM Interleukin-33, 20 mM sodium phosphate, 100 mM sodium chloride, 5 mM [U-100% 2H] beta-mercaptoethanol, 100% D2O | 100% D2O
NMR sample composition 1 mM [U-100% 13C; U-100% 15N] Interleukin-33, 20 mM sodium phosphate, 100 mM sodium chloride, 5 mM beta-mercaptoethanol, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition 1 mM [U-100% 13C; U-100% 15N] Interleukin-33, 20 mM sodium phosphate, 100 mM sodium chloride, 5 mM [U-100% 2H] beta-mercaptoethanol, 100% D2O | 100% D2O
Resolution not provided
4KC3 Cytokine/receptor binary complex Deposited 2013-04-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 112–270（159 aa） Fragment：UNP residues 112-270
Non-standard monomer：Yes (specific site not provided by mmCIF) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；291 K；12% PEG3350, 100 mM Sodium Malonate pH 4.5, 7% v/v MPD, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.27 Å R-free 0.283
9WWH Crystal structure of IL-33 and antibody Tozorakimab fab binary complex Deposited 2025-09-23 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain D 117–268（152 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；0.2 M Magnesium chloride hexahydrate 0.1 M Na citrate tribasic dihydrate pH 5.0 15% w/v Polyethylene glycol 20,000
Resolution 3.51 Å R-free 0.259
9WWH Crystal structure of IL-33 and antibody Tozorakimab fab binary complex Deposited 2025-09-23 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 117–268（152 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；0.2 M Magnesium chloride hexahydrate 0.1 M Na citrate tribasic dihydrate pH 5.0 15% w/v Polyethylene glycol 20,000
Resolution 3.51 Å R-free 0.259
9WWH Crystal structure of IL-33 and antibody Tozorakimab fab binary complex Deposited 2025-09-23 Assembly 3 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain C 117–268（152 aa）
Chain D 117–268（152 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；0.2 M Magnesium chloride hexahydrate 0.1 M Na citrate tribasic dihydrate pH 5.0 15% w/v Polyethylene glycol 20,000
Resolution 3.51 Å R-free 0.259
9X05 IL-33 and Itepekimab fab and Tozorakimab fab ternary complex structure Deposited 2025-09-29 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 113–270（158 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.64 Å
9X0J IL-33 and Etokimab fab and Tozorakimab fab ternary complex structure Deposited 2025-09-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 113–270（158 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.57 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.