Current Protein Identity:P01876
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1IGA MODEL OF HUMAN IGA1 DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING Deposited 1998-12-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–353(353 aa)
Fragment:CHAINS A AND B, HEAVY, CHAINS C AND D, LIGHT
Chain B
1–353(353 aa)
Fragment:CHAINS A AND B, HEAVY, CHAINS C AND D, LIGHT
|
Not recorded | No recorded non-water small molecule | SOLUTION SCATTERING | mmCIF provides none of the parsed conditions | Resolution not provided |
| 1OW0 Crystal structure of human FcaRI bound to IgA1-Fc Deposited 2003-03-27 | Assembly 1 Other combination Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
122–335(214 aa)
Fragment:Fc region
Chain B
122–335(214 aa)
Fragment:Fc region
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;296 K;magnesium sulfate heptahydrate, MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 296K
|
Resolution 3.10 Å R-free 0.284 |
| 1OW0 Crystal structure of human FcaRI bound to IgA1-Fc Deposited 2003-03-27 | Assembly 4 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
122–335(214 aa)
Fragment:Fc region
Chain B
122–335(214 aa)
Fragment:Fc region
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;296 K;magnesium sulfate heptahydrate, MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 296K
|
Resolution 3.10 Å R-free 0.284 |
| 2QEJ Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 Deposited 2007-06-26 | Assembly 1 Other combination Heteromer;Protein × 4 PDB declaration: pentameric(5) Review required |
Chain A
123–336(214 aa)
Fragment:FC REGION
Chain B
123–336(214 aa)
Fragment:FC REGION
|
Not recorded | GOL GLYCEROL × 5 CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 6.5;291 K;12% PEG 8000, 66 mM sodium cacodylate pH 6.5, 130 mM calcium acetate, VAPOR DIFFUSION, temperature 291K
|
Resolution 3.20 Å R-free 0.312 |
| 2QTJ Solution structure of human dimeric immunoglobulin A Deposited 2007-08-02 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–475(475 aa)
Chain B
1–475(475 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION SCATTERING | mmCIF provides none of the parsed conditions | Resolution not provided |
| 2QTJ Solution structure of human dimeric immunoglobulin A Deposited 2007-08-02 | Assembly 2 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–475(475 aa)
Chain D
1–475(475 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION SCATTERING | mmCIF provides none of the parsed conditions | Resolution not provided |
| 3CHN Solution structure of human secretory IgA1 Deposited 2008-03-10 | Assembly 1 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count |
Chain A
1–353(353 aa)
Chain B
1–353(353 aa)
Chain C
1–353(353 aa)
Chain D
1–353(353 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION SCATTERING | mmCIF provides none of the parsed conditions | Resolution not provided |
| 6LX3 Cryo-EM structure of human secretory immunoglobulin A Deposited 2020-02-10 | Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
122–353(232 aa)
Chain B
122–353(232 aa)
Chain C
122–353(232 aa)
Chain D
122–353(232 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.15 Å |
| 6LXW Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA Deposited 2020-02-12 | Assembly 1 Insufficient information Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain A
122–353(232 aa)
Chain B
122–353(232 aa)
Chain C
122–353(232 aa)
Chain D
122–353(232 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.27 Å |
| 6UE7 Structure of dimeric sIgA complex Deposited 2019-09-20 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
123–353(231 aa)
Fragment:UNP residues 123-353
Chain B
123–353(231 aa)
Fragment:UNP residues 123-353
Chain F
123–353(231 aa)
Fragment:UNP residues 123-353
Chain G
123–353(231 aa)
Fragment:UNP residues 123-353
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |
| 6XJA Streptococcus Pneumoniae IgA1 Protease with IgA1 substrate Deposited 2020-06-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
122–331(210 aa)
Chain B
122–331(210 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7;20 mM Hepes, pH 7
150 mM NaCl
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å |
| 7UVL IgA1 Protease with IgA1 substrate Deposited 2022-05-02 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
123–331(209 aa)
Chain B
123–331(209 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.56 Å |
| 8SKU Structure of human SIgA1 in complex with human CD89 (FcaR1) Deposited 2023-04-20 | Assembly 1 Other combination Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–353(353 aa)
Chain B
1–353(353 aa)
Chain C
1–353(353 aa)
Chain D
1–353(353 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8SKV Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4) Deposited 2023-04-20 | Assembly 1 Other combination Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
1–353(353 aa)
Chain B
1–353(353 aa)
Chain C
1–353(353 aa)
Chain D
1–353(353 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å |
| 9MBZ Cryo-EM structure of human FcRL4 bound to IgA-Fc/J Deposited 2025-03-17 | Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
122–353(232 aa)
Chain B
122–353(232 aa)
Chain C
122–353(232 aa)
Chain D
122–353(232 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY | mmCIF provides none of the parsed conditions | Resolution 3.30 Å |
| 9OFR CRYSTAL STRUCTURE OF THE HUMAN IGA1 FC FRAGMENT-FC-ALPHA RECEPTOR (CD89) COMPLEX Deposited 2025-04-30 | Assembly 1 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
123–335(213 aa)
Fragment:FC fragment, UNP residues 123-335
Chain B
123–335(213 aa)
Fragment:FC fragment, UNP residues 123-335
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;294 K;0.15M sodium chloride
0.1M Tris-HCl pH 8.0
8% PEG 6000
|
Resolution 2.65 Å R-free 0.264 |
| 9OFR CRYSTAL STRUCTURE OF THE HUMAN IGA1 FC FRAGMENT-FC-ALPHA RECEPTOR (CD89) COMPLEX Deposited 2025-04-30 | Assembly 2 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain E
123–335(213 aa)
Fragment:FC fragment, UNP residues 123-335
Chain G
123–335(213 aa)
Fragment:FC fragment, UNP residues 123-335
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;294 K;0.15M sodium chloride
0.1M Tris-HCl pH 8.0
8% PEG 6000
|
Resolution 2.65 Å R-free 0.264 |
| 9R2E Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1 Deposited 2025-04-30 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain P
123–335(213 aa)
Chain Q
123–335(213 aa)
|
Not recorded | EDO 1,2-ETHANEDIOL × 4 PEG DI(HYDROXYETHYL)ETHER × 5 MG MAGNESIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;16% (w/v) PEG8000, 20% (v/v) Glycerol, 0.16 M MgAcetate, 0.08 M Na
Cacodylate pH 6.50
|
Resolution 2.54 Å R-free 0.252 |