Current Protein Identity：P02751
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1E88 Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin Deposited 2000-09-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
305–464（160 aa）
Fragment：6F11F22F2, RESIDUES 305-464
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | SOLUTION NMR |
NMR measurement conditions
pH 4.5；298 K
NMR sample composition
2MM 6F11F22F2, 20MM PHOSPHATE BUFFER
|
Resolution not provided |
| 1E8B Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin Deposited 2000-09-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
305–464（160 aa）
Fragment：6F11F22F2, RESIDUES 305-464
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | SOLUTION NMR |
NMR measurement conditions
pH 4.5；298 K
NMR sample composition
2MM 6F11F22F2, 20MM PHOSPHATE BUFFER
|
Resolution not provided |
| 1FBR FOURTH AND FIFTH FIBRONECTIN TYPE I MODULE PAIR Deposited 1995-08-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
183–275（93 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR | mmCIF provides none of the parsed conditions | Resolution not provided |
| 1FNA CRYSTAL STRUCTURE OF THE TENTH TYPE III CELL ADHESION MODULE OF HUMAN FIBRONECTIN Deposited 1994-01-11 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1452–1542（91 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 1.80 Å |
| 1FNF FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 Deposited 1995-09-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1173–1540（368 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.8；pH 5.8
|
Resolution 2.00 Å R-free 0.308 |
| 1FNH CRYSTAL STRUCTURE OF HEPARIN AND INTEGRIN BINDING SEGMENT OF HUMAN FIBRONECTIN Deposited 1999-01-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1721–1991（271 aa）
Fragment：HEPARIN AND INTEGRIN BINDING
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；CRYSTALLIZATION CONDITIONS: 0.1M HEPES, PH7.5, 0.8M NA, K TARTRATE
|
Resolution 2.80 Å R-free 0.295 |
| 1J8K NMR STRUCTURE OF THE FIBRONECTIN EDA DOMAIN, NMR, 20 STRUCTURES Deposited 2001-05-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1631–1724（94 aa）
Fragment：EXTRA DOMAIN 2 (RESIDUES 1631-1724)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；293 K；Ionic strength (raw mmCIF value) 400mM sodium sulfate；Pressure 1
NMR sample composition
2mM EDA U-15N,13C; 50mM phosphate buffer, 400mM sodium sulfate; 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 1O9A Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae Deposited 2002-12-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
48–140（93 aa）
Fragment：N-TERMINAL F1 MODULE PAIR, RESIDUES 48-140
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5；298 K
|
Resolution not provided |
| 1OWW Solution structure of the first type III module of human fibronectin determined by 1H, 15N NMR spectroscopy Deposited 2003-03-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
608–701（94 aa）
Fragment：Residues 608-701 of SWS P02751
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6；313 K；Ionic strength (raw mmCIF value) unbuffered；Pressure ambient
NMR sample composition
1-2 mM [U-15N] protein, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 1Q38 Anastellin Deposited 2003-07-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
631–705（75 aa）
Fragment：Type 3 (FN3) domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 150；Pressure ambient
NMR sample composition
1.5 mM anastellin U-15N, 10 mM Na2HPO4, 1.8 mM KH2PO4, 140 mM NaCl, 2.7 mM KCl, 2 mM CHAPS | 90% H2O/10% D2O
NMR sample composition
1.5 mM anastellin U-15N,13C, 10 mM Na2HPO4, 1.8 mM KH2PO4, 140 mM NaCl, 2.7 mM KCl, 2 mM CHAPS | 90% H2O/10% D2O
|
Resolution not provided |
| 1QGB SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE PAIR FROM HUMAN FIBRONECTIN Deposited 1999-04-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
48–140（93 aa）
Fragment：N-TERMINAL F1 MODULE PAIR
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 4；310 K
NMR sample composition
2.2 mM [U-15N] 1F1-2F1, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 1QO6 Solution structure of a pair of modules from the gelatin-binding domain of fibronectin Deposited 1999-11-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
305–405（101 aa）
Fragment：FIBRONECTIN TYPE-I AND FIBRONECTIN TYPE-II MODULE PAIR FROM COLLAGEN-BINDING DOMAIN
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 4.5；310 K；Pressure 1
|
Resolution not provided |
| 1TTF THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS Deposited 1993-07-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1447–1540（94 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR | mmCIF provides none of the parsed conditions | Resolution not provided |
| 1TTG THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS Deposited 1993-07-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1447–1540（94 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR | mmCIF provides none of the parsed conditions | Resolution not provided |
| 2CG6 Second and third fibronectin type I module pair (crystal form I). Deposited 2006-02-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：RESIDUES 93-182 (62-151 IN COORDINATES)
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 4.5；0.2 M AMMONIUM SULPHATE, 0.1M NA ACETATE PH 4.5, 2% MPD, 5% PEG MME 550
|
Resolution 1.55 Å R-free 0.231 |
| 2CG7 SECOND AND THIRD FIBRONECTIN TYPE I MODULE PAIR (CRYSTAL FORM II). Deposited 2006-02-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：RESIDUES 93-182 (62-151 IN COORDINATES)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；WATER AND 0.02% SODIUM AZIDE, pH 7.00
|
Resolution 1.20 Å R-free 0.219 |
| 2CK2 Structure of core-swapped mutant of fibronectin Deposited 2006-04-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1447–1542（96 aa）
Fragment：RESIDUES 1447-1542
Chain B
1447–1542（96 aa）
Fragment：RESIDUES 1447-1542
|
Mutation：YES Mutation：YES | ACE ACETYL GROUP × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.1；50% PEG-400, 0.1 M ACTEATE, 0.2 M LITHIUM SULPHATE, PH 5.1
|
Resolution 2.00 Å R-free 0.268 |
| 2CKU Solution structure of 2F13F1 from human fibronectin Deposited 2006-04-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：2ND AND 3RD F1 MODULES, RESIDUES 93-182 (62-151 IN COORDINATES)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
298 K
|
Resolution not provided |
| 2EC3 Solution structure of the 11th FN1 domain from human Fibronectin 1 Deposited 2007-02-09 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2239–2299（61 aa）
Fragment：Fibronectin type-I
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition
1.14 mM 13C, 15N-labeled protein; 20mM d-Tris-HCl (pH7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2FN2 SOLUTION NMR STRUCTURE OF THE GLYCOSYLATED SECOND TYPE TWO MODULE OF FIBRONECTIN, 20 STRUCTURES Deposited 1997-08-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
375–433（59 aa）
Fragment：RESIDUES 375 - 433
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | SOLUTION NMR |
NMR measurement conditions
pH 4.5；298 K；Ionic strength (raw mmCIF value) 0 mM；Pressure 10E+5 PA
NMR sample composition
H2O/D2O(9:1) OR D2O
|
Resolution not provided |
| 2FNB NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES Deposited 1998-12-16 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1261–1355（95 aa）
Fragment：TYPE III DOMAIN
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 63 mM；Pressure 1
|
Resolution not provided |
| 2H41 Solution structure of the second type III domain of human Fibronectin: minimized average structure Deposited 2006-05-23 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
721–809（89 aa）
Fragment：Fibronectin type-III 2(2F3)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 20mM NaCl, 20mM Na2HPO4；Pressure ambient
NMR sample composition
2.5mM 2F3 U-15N, 20mM NaPi pH 7.0, 20mM NaCl, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
2mM 2F3 U-13C,15N, 20mM NaPi pH 7.0, 20mM NaCl, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
2mM 2F3 U-13C,15N, 20mM NaPi pH 7.0, 20mM NaCl, 100% D2O | 100% D2O
NMR sample composition
1mM 2F3 U-15N, 20mM NaPi pH 7.0, 20mM NaCl, 4% Radially compressed polyacrylamide gel, 95% H2O, 5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2H45 Solution structure of the second type III domain of human Fibronectin: ensemble of 25 structures Deposited 2006-05-23 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
721–809（89 aa）
Fragment：Fibronectin type-III 2(2F3)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 20mM NaCl, 20mM Na2HPO4；Pressure ambient
NMR sample composition
2.5mM 2F3 U-15N, 20mM NaPi pH 7.0, 20mM NaCl, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
2mM 2F3 U-13C,15N, 20mM NaPi pH 7.0, 20mM NaCl, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
2mM 2F3 U-13C,15N, 20mM NaPi pH 7.0, 20mM NaCl, 100% D2O | 100% D2O
NMR sample composition
1mM 2F3 U-15N, 20mM NaPi pH 7.0, 20mM NaCl, 4% Radially compressed polyacrylamide gel, 95% H2O, 5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2HA1 Complex of the first and second type III domains of human Fibronectin in solution Deposited 2006-06-12 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
609–809（201 aa）
Fragment：Fibronectin first and second type III domain pair (1F3-2F3)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 150mM NaCl, 20mM Na2HPO3；Pressure ambient
NMR sample composition
1.0mM 1F3-2F3 U-15N, 150mM NaCl, 20mM NaPi pH 7.0, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
1.0mM 1F3-2F3 U-15N, 13C, 150mM NaCl, 20mM NaPi pH 7.0, 95% H2O, 5% D2O | 95% H2O/5% D2O
NMR sample composition
0.6mM 1F3-2F3 U-15N, 150mM NaCl, 20mM NaPi pH 7.0, 4% Radially compressed polyacrylamide gel, 95% H2O, 5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2N1K Structure of the Third Type III Domain from Human Fibronectin Deposited 2015-04-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
808–905（98 aa）
Fragment：third FN3 domain (UNP residues 808-905)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.5；298.15 K；Ionic strength (raw mmCIF value) 0.17；Pressure ambient
NMR sample composition
0.6 mM [U-99% 13C; U-99% 15N] 3FN3, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM [U-99% 15N] 3FN3, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM 3FN3, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM 3FN3, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 100% D2O | 100% D2O
NMR sample composition
0.9 mM [U-99% 13C; U-99% 15N] 3FN3, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 0.9 mM 3FN3, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2OCF Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody Deposited 2006-12-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain D
1447–1540（94 aa）
Fragment：E2#23 FN3 MONOBODY, Fibronectin type III Domain 10, Residues 1447-1540
|
Mutation：R1452T, D1453K, R1524L, G1525R, D1526L, S1527M, P1528L, S1530G | EST ESTRADIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；289 K；2.5M NaCl, 0.1M Imidazole, pH 8.0, 0.2M Zn(OAc)2, VAPOR DIFFUSION, SITTING DROP, temperature 289K
|
Resolution 2.95 Å R-free 0.251 |
| 2RKY Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
183–275（93 aa）
Fragment：UNP residues 183-275
|
Not recorded | SCN THIOCYANATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；100mM Tris-HCl, pH8.5, 0.15M Potassium thiocyanate, 20% PEG400, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.80 Å R-free 0.216 |
| 2RKY Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
183–275（93 aa）
Fragment：UNP residues 183-275
|
Not recorded | SCN THIOCYANATE ION × 3 K POTASSIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；100mM Tris-HCl, pH8.5, 0.15M Potassium thiocyanate, 20% PEG400, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.80 Å R-free 0.216 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | SIN SUCCINIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | SIN SUCCINIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | SIN SUCCINIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain E
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RKZ Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 Deposited 2007-10-18 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain F
93–182（90 aa）
Fragment：UNP residues 93-182
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.8M SUCCINIC ACID, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.261 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain F
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain I
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 2RL0 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2007-10-18 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain K
184–272（89 aa）
Fragment：UNP residues 184-272
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.2；291 K；0.2M NACL, 0.1M BIS TRIS, 14% PEG3350, pH6.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.00 Å R-free 0.266 |
| 3CAL Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2008-02-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：UNP residues 93-182, Second and third F1 modules
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.95M succinic acid, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 1.70 Å R-free 0.217 |
| 3CAL Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 Deposited 2008-02-20 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
93–182（90 aa）
Fragment：UNP residues 93-182, Second and third F1 modules
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；0.95M succinic acid, pH7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 1.70 Å R-free 0.217 |
| 3CH8 The crystal structure of PDZ-Fibronectin fusion protein Deposited 2008-03-08 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1538–1631（94 aa）
|
Not recorded | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；31% isopropanol, 0.1M HEPES, 0.2M MgCl2, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.260 |
| 3EJH Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide Deposited 2008-09-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
516–608（93 aa）
Fragment：8-9FnI
|
Mutation：N528Q, R534K | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；2.5 M NaCl, 0.1 M BisTris pH 6.5 , VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.242 |
| 3EJH Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide Deposited 2008-09-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
516–608（93 aa）
Fragment：8-9FnI
|
Mutation：N528Q, R534K | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；2.5 M NaCl, 0.1 M BisTris pH 6.5 , VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.242 |
| 3GXE Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair Deposited 2009-04-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
516–608（93 aa）
Fragment：8-9FnI, UNP residues 516-608
|
Mutation：N528Q, R534K | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293.1 K；0.1M HEPES pH 7.5, 4.3M NaCl, VAPOR DIFFUSION, SITTING DROP, temperature 293.1K
|
Resolution 2.60 Å R-free 0.271 |
| 3GXE Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair Deposited 2009-04-02 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
516–608（93 aa）
Fragment：8-9FnI, UNP residues 516-608
|
Mutation：N528Q, R534K | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293.1 K；0.1M HEPES pH 7.5, 4.3M NaCl, VAPOR DIFFUSION, SITTING DROP, temperature 293.1K
|
Resolution 2.60 Å R-free 0.271 |
| 3R8Q Structure of Fibronectin domain 12-14 Deposited 2011-03-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1722–1992（271 aa）
Fragment：unp residues 1722-1992
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；291 K；0.1 M Na HEPES, 0.8 M sodium dihydrogen phosphate, 0.8 M potassium dihydrogen phosphate, supplemented with 35% glycerol for cryo-protection, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.40 Å R-free 0.236 |
| 3ZRZ Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of Streptococcus pyogenes SfbI-5 Deposited 2011-06-21 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：SECOND AND THIRD F1 MODULES, RESIDUES 93-182
|
Not recorded | SO4 SULFATE ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；CRYSTALS OF THE PROTEIN/PEPTIDE COMPLEX (0.3 MM/3.5 MM, PH 7.7) WERE GROWN USING SITTING DROP VAPOUR DIFFUSION FROM A 1:1 DILUTION WITH WELL SOLUTION (0.1 M TRIS PH 7.0, 1.5 M (NH4)2SO4 AT 18 DEGREES CENTIGRADE
|
Resolution 1.70 Å R-free 0.222 |
| 3ZRZ Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of Streptococcus pyogenes SfbI-5 Deposited 2011-06-21 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
93–182（90 aa）
Fragment：SECOND AND THIRD F1 MODULES, RESIDUES 93-182
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；CRYSTALS OF THE PROTEIN/PEPTIDE COMPLEX (0.3 MM/3.5 MM, PH 7.7) WERE GROWN USING SITTING DROP VAPOUR DIFFUSION FROM A 1:1 DILUTION WITH WELL SOLUTION (0.1 M TRIS PH 7.0, 1.5 M (NH4)2SO4 AT 18 DEGREES CENTIGRADE
|
Resolution 1.70 Å R-free 0.222 |
| 4GH7 Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8 Deposited 2012-08-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1173–1448（276 aa）
Fragment：Fn7B8, UNP residues 1173-1448
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；17-19%(w/v) PEG3350, 0.1M Na-citrate, pH 5.5-6.0, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.259 |
| 4GH7 Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8 Deposited 2012-08-07 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1173–1448（276 aa）
Fragment：Fn7B8, UNP residues 1173-1448
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；17-19%(w/v) PEG3350, 0.1M Na-citrate, pH 5.5-6.0, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.259 |
| 4LXO Crystal structure of 9,10Fn3-elegantin chimera Deposited 2013-07-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1357–1540（184 aa）
|
Mutation：L1408P, V1490C, T1491R, G1492A, S1496N, A1498D, S1499C | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；0.2M calcium acetate, 7%(w/v) PEG10000, pH 7.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.42 Å R-free 0.193 |
| 4LXO Crystal structure of 9,10Fn3-elegantin chimera Deposited 2013-07-30 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1357–1540（184 aa）
|
Mutation：L1408P, V1490C, T1491R, G1492A, S1496N, A1498D, S1499C | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；0.2M calcium acetate, 7%(w/v) PEG10000, pH 7.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.42 Å R-free 0.193 |
| 4MMX Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin Deposited 2013-09-09 | Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1539–1631（93 aa）
Fragment：Fibronectin type-III domain 10 (UNP residues 1448-1540)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 MN MANGANESE (II) ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；277.15 K；12% PEG3350, 0.8 M sodium chloride, 0.1 M sodium acetate, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
|
Resolution 3.32 Å R-free 0.269 |
| 4MMY Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif Deposited 2013-09-09 | Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1448–1540（93 aa）
Fragment：Fibronectin type-III domain 10 (UNP residues 1448-1540)
|
Mutation：TGRGDSPASS to IARGDWNDG | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 MN MANGANESE (II) ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；277.15 K；12% PEG3350, 0.8 M sodium chloride, 0.1 M sodium acetate, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
|
Resolution 3.18 Å R-free 0.252 |
| 4MMZ Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin Deposited 2013-09-09 | Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1539–1631（93 aa）
Fragment：Fibronectin type-III domain 10 (UNP residues 1448-1540)
|
Mutation：GRGDSPAS to PRGDWNEG | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 MN MANGANESE (II) ION × 8 NA SODIUM ION × 1 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；277.15 K；12% PEG3350, 0.8 M sodium chloride, 0.1 M sodium acetate, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
|
Resolution 3.10 Å R-free 0.255 |
| 4PZ5 Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi Deposited 2014-03-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
93–182（90 aa）
Fragment：2FN1-3FN1, UNP RESIDUES 93-182
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.9；291 K；1.4 M Na/K phosphate, pH 6.9, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 1.96 Å R-free 0.199 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain J
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
1539–1635（97 aa）
|
Not recorded | CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain E
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain F
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain G
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain H
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5DFT Structure of the Eleventh Type III Domain from Human Fibronectin Deposited 2015-08-27 | Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain I
1539–1635（97 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.1M sodium citrate, 0.1M citric acid and 0.1M sodium iodine
|
Resolution 2.50 Å R-free 0.248 |
| 5J6Z Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin Deposited 2016-04-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
806–834（29 aa）
Fragment：residues 806-834
Chain B
631–705（75 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.5；298 K；Ionic strength (raw mmCIF value) 166；Pressure 100000
NMR sample composition
0.6 mM [U-99% 13C; U-99% 15N] AB, 0.6 mM anastellin, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM AB, 0.6 mM [U-99% 13C; U-99% 15N] anastellin, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM [U-99% 15N] AB, 0.6 mM anastellin, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.6 mM AB, 0.6 mM [U-99% 15N] anastellin, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 140 mM sodium chloride, 2.7 mM potassium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 5M0A Solution structure of isolated 15th Fibronectin III domain from human fibronectin Deposited 2016-10-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2108–2193（86 aa）
Fragment：15th Fibronectin III domain, UNP residues 2108-2193
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5；298 K；Ionic strength (raw mmCIF value) 161；Pressure 1
NMR measurement conditions
pH 6.5；298 K；Ionic strength (raw mmCIF value) 161；Pressure 1
NMR sample composition
10 mM TRIS, 150 mM sodium chloride, 0.02 ug/mL TSP, 1 mM sodium azide, 0.35 mM [U-13C; U-15N] 15th Fibronectin III domain from human fibronectin, 0.5 mM EDTA, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
10 mM [U-2H] TRIS, 0.35 mM [U-13C; U-15N] 15th Fibronectin III domain from human fibronectin, 150 mM sodium chloride, 1 mM sodium azide, 0.02 ug/mL TSP, 0.5 mM EDTA, 100% D2O | 100% D2O
|
Resolution not provided |
| 5N47 Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin Deposited 2017-02-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1173–1448（276 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；298 K；17 % (w/v) PEG3350, 0.2 M NaCl, 0.1 M Na-malonate
|
Resolution 3.00 Å R-free 0.241 |
| 5N47 Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin Deposited 2017-02-10 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1173–1448（276 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；298 K；17 % (w/v) PEG3350, 0.2 M NaCl, 0.1 M Na-malonate
|
Resolution 3.00 Å R-free 0.241 |
| 5N47 Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin Deposited 2017-02-10 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain F
1173–1448（276 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；298 K；17 % (w/v) PEG3350, 0.2 M NaCl, 0.1 M Na-malonate
|
Resolution 3.00 Å R-free 0.241 |
| 5N48 Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin Deposited 2017-02-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1266–1357（92 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；29 % (w/v) PEG4000, 0.1 M Na-malonate
|
Resolution 1.60 Å R-free 0.208 |
| 5N48 Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin Deposited 2017-02-10 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1266–1357（92 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；29 % (w/v) PEG4000, 0.1 M Na-malonate
|
Resolution 1.60 Å R-free 0.208 |
| 6HNF Structure in solution of human fibronectin type III-domain 14 Deposited 2018-09-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1904–1991（88 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.4；298 K；Ionic strength (raw mmCIF value) 162.7；Pressure 1030
NMR sample composition
1.0 mM [U-13C; U-15N] FNIII14, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 6MFA Fragment of human fibronectin containing the 4th-7th type III domains Deposited 2018-09-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
903–1268（366 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.1 M MES pH 5.5, 7% PEG 6000
|
Resolution 1.75 Å R-free 0.238 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain J
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 11 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain K
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 12 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain L
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 13 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
1085–1173（89 aa）
Chain G
1085–1173（89 aa）
Chain H
1085–1173（89 aa）
Chain J
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 14 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
1085–1173（89 aa）
Chain D
1085–1173（89 aa）
Chain F
1085–1173（89 aa）
Chain L
1085–1173（89 aa）
|
Not recorded | GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 15 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
1085–1173（89 aa）
Chain E
1085–1173（89 aa）
Chain I
1085–1173（89 aa）
Chain K
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1085–1173（89 aa）
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain E
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain F
1085–1173（89 aa）
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain G
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain H
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6MSV Structure of the 6th type III domain from human fibronectin Deposited 2018-10-18 | Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain I
1085–1173（89 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.0 M Ammonium Sulfate
|
Resolution 2.40 Å R-free 0.295 |
| 6NAJ Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin. Deposited 2018-12-05 | Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1539–1629（91 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 7 MN MANGANESE (II) ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；277 K；100 M Sodium Acetate, PEG4000, 800 mM Sodium Chloride.
|
Resolution 3.10 Å R-free 0.268 |
| 6XAX Structure of a fragment of human fibronectin containing the 11th type III domain, extra domain A, and the 12th type III domain Deposited 2020-06-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1630–1903（274 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.2M Ca(CH3COO)2, 0.1M imidazole pH 8.0, 10%(w/v) PEG 8000
|
Resolution 2.40 Å R-free 0.312 |
| 6XAX Structure of a fragment of human fibronectin containing the 11th type III domain, extra domain A, and the 12th type III domain Deposited 2020-06-04 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1630–1903（274 aa）
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.2M Ca(CH3COO)2, 0.1M imidazole pH 8.0, 10%(w/v) PEG 8000
|
Resolution 2.40 Å R-free 0.312 |
| 6XAY Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains Deposited 2020-06-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1447–1722（276 aa）
|
Mutation：V1643G | GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.5M (NH4)2SO4, 0.1M Citric acid pH 4.0, 30%(v/v)PEG 600, 10%(v/v) glycerol
|
Resolution 2.48 Å R-free 0.296 |
| 6XAY Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains Deposited 2020-06-05 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1447–1722（276 aa）
|
Mutation：V1643G | GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.5M (NH4)2SO4, 0.1M Citric acid pH 4.0, 30%(v/v)PEG 600, 10%(v/v) glycerol
|
Resolution 2.48 Å R-free 0.296 |
| 6XAY Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains Deposited 2020-06-05 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1447–1722（276 aa）
|
Mutation：V1643G | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.5M (NH4)2SO4, 0.1M Citric acid pH 4.0, 30%(v/v)PEG 600, 10%(v/v) glycerol
|
Resolution 2.48 Å R-free 0.296 |
| 6XAY Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains Deposited 2020-06-05 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
1447–1722（276 aa）
|
Mutation：V1643G | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；0.5M (NH4)2SO4, 0.1M Citric acid pH 4.0, 30%(v/v)PEG 600, 10%(v/v) glycerol
|
Resolution 2.48 Å R-free 0.296 |
| 7NWL Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp Deposited 2021-03-17 | Assembly 1 Other combination Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain C
1173–1540（368 aa）
|
Not recorded | MN MANGANESE (II) ION × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.10 Å |
| 8PEQ Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) Deposited 2023-06-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1174–1447（274 aa）
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.3；298 K；500 mM lithium sulfate, 15% PEG 8000 (w/v)
|
Resolution 2.32 Å R-free 0.251 |
| 8PEQ Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) Deposited 2023-06-14 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1174–1447（274 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.3；298 K；500 mM lithium sulfate, 15% PEG 8000 (w/v)
|
Resolution 2.32 Å R-free 0.251 |
| 8PEQ Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) Deposited 2023-06-14 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1174–1447（274 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.3；298 K；500 mM lithium sulfate, 15% PEG 8000 (w/v)
|
Resolution 2.32 Å R-free 0.251 |
| 9P6S Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10) Deposited 2025-06-19 | Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1449–1631（183 aa）
|
Not recorded | MN MANGANESE (II) ION × 7 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.61 Å |