Current Protein Identity:P02920
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1PV6 Crystal structure of lactose permease Deposited 2003-06-26 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Mutation:C154G | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.50 Å R-free 0.337 |
| 1PV6 Crystal structure of lactose permease Deposited 2003-06-26 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–417(417 aa)
|
Mutation:C154G | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.50 Å R-free 0.337 |
| 1PV7 Crystal structure of lactose permease with TDG Deposited 2003-06-26 | Assembly 1 Other combination Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Mutation:C154G | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.60 Å R-free 0.296 |
| 1PV7 Crystal structure of lactose permease with TDG Deposited 2003-06-26 | Assembly 2 Other combination Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–417(417 aa)
|
Mutation:C154G | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.60 Å R-free 0.296 |
| 2CFP Sugar Free Lactose Permease at acidic pH Deposited 2006-02-22 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Mutation:YES | HG MERCURY (II) ION × 5 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 3.30 Å R-free 0.328 |
| 2CFQ Sugar Free Lactose Permease at neutral pH Deposited 2006-02-22 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Mutation:YES | HG MERCURY (II) ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.95 Å R-free 0.298 |
| 2V8N Wild-type Structure of Lactose Permease Deposited 2007-08-09 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 3.60 Å R-free 0.333 |
| 2V8N Wild-type Structure of Lactose Permease Deposited 2007-08-09 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–417(417 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 3.60 Å R-free 0.333 |
| 2Y5Y Crystal structure of LacY in complex with an affinity inactivator Deposited 2011-01-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–417(417 aa)
Chain B
1–417(417 aa)
|
Mutation:YES Mutation:YES | BA BARIUM ION × 2 TGA 2-sulfanylethyl beta-D-galactopyranoside × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6;PH 6
|
Resolution 3.38 Å R-free 0.303 |
| 4ZYR Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG) Deposited 2015-05-22 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–417(417 aa)
|
Mutation:G46W, G262W | 9PG 4-nitrophenyl alpha-D-galactopyranoside × 1 BNG nonyl beta-D-glucopyranoside × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;295 K;1.0 M NaCl 0.05 M Tris (pH8.0) 26% PEG 600
|
Resolution 3.31 Å R-free 0.278 |
| 4ZYR Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG) Deposited 2015-05-22 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–417(417 aa)
|
Mutation:G46W, G262W | 9PG 4-nitrophenyl alpha-D-galactopyranoside × 1 BNG nonyl beta-D-glucopyranoside × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;295 K;1.0 M NaCl 0.05 M Tris (pH8.0) 26% PEG 600
|
Resolution 3.31 Å R-free 0.278 |
| 5GXB crystal structure of a LacY/Nanobody complex Deposited 2016-09-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–417(417 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
LIPIDIC CUBIC PHASE;293 K;100mM MES pH 6.0, 100mM (NH4)2C4H4O6, 43% PEG 400
|
Resolution 3.30 Å R-free 0.346 |
| 6C9W Crystal Structure of a ligand bound LacY/Nanobody Complex Deposited 2018-01-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–417(417 aa)
Fragment:Full
|
Mutation:G46W, G262W | 9PG 4-nitrophenyl alpha-D-galactopyranoside × 1 BNG nonyl beta-D-glucopyranoside × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;295 K;0.1 M MgCl2, 28% PEG1000, 0.1 M Tris-HCl, pH 8.5
|
Resolution 3.00 Å R-free 0.295 |
| 8Y9Y Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+1C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain B
315–334(20 aa)
|
Mutation:T1M,R2A,L3K,A4K,G5T,C53A | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.29 Å |
| 8YA0 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain B
316–332(17 aa)
|
Mutation:R2A, L3K, A4K, G5T, C14T, F17L | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.97 Å |
| 8YA2 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+20C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain B
315–334(20 aa)
|
Mutation:T1M,R2A,L3K,A4K,G5T,E45C,C53A | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.84 Å |
| 8YA3 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) treated with DTT Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
315–334(20 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.27 Å |
| 9XOU CryoEM structure of LacY with Trimbody Deposited 2025-11-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 9 PDB declaration: nonameric(9) Consistent with protein count |
Chain G
1–417(417 aa)
Chain H
1–417(417 aa)
Chain I
1–417(417 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.50 Å |