Current Protein Identity：P08799
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1D0X DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH M-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：MYOSIN MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 MNQ M-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 MM NACL 3 MM DTT, pH 7.0, MICROBATCH, temperature 4.0K
|
Resolution 2.00 Å |
| 1D0Y DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM FLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：S1DC MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 ONP O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 MM NACL 3 MM DTT, pH 7.0, MICROBATCH, temperature 4.0K
|
Resolution 2.00 Å |
| 1D0Z DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH P-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：S1DC MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 PNQ P-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 mM NaCl 3 mM DTT, pH 7.0, microbatch, temperature 4.0K
|
Resolution 2.00 Å |
| 1D1A DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O,P-DINITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：S1DC MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 DAE O,P-DINITROPHENYL AMINOETHYLDIPHOSPHATE-BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 MM NACL 3 MM DTT, pH 7.0, MICROBATCH, temperature 4.0K
|
Resolution 2.00 Å |
| 1D1B DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH O,P-DINITROPHENYL AMINOPROPYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：S1DC MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 DAQ O,P-DINITROPHENYL AMINOPROPYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 mM NaCl 3 mM DTT, pH 7.0, microbatch, temperature 4.0K
|
Resolution 2.00 Å |
| 1D1C DICTYOSTELIUM MYOSIN S1DC (MOTOR DOMAIN FRAGMENT) COMPLEXED WITH N-METHYL-O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE. Deposited 1999-09-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：S1DC MOTOR DOMAIN
|
Mutation：Q760P, R761N | MG MAGNESIUM ION × 1 NMQ N-METHYL O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7；277 K；8.3 % PEG 8000 125 MM NACL 3 MM DTT, pH 7.0, MICROBATCH, temperature 4.0K
|
Resolution 2.30 Å |
| 1FMV CRYSTAL STRUCTURE OF THE APO MOTOR DOMAIN OF DICTYOSTELLIUM MYOSIN II Deposited 2000-08-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 7.5；277 K；8% Peg 8000, 50 mM Hepes, 1 mM DTT, pH 7.5, microbatch, temperature 4K
|
Resolution 2.10 Å R-free 0.280 |
| 1FMW CRYSTAL STRUCTURE OF THE MGATP COMPLEX FOR THE MOTOR DOMAIN OF DICTYOSTELIUM MYOSIN II Deposited 2000-08-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Not recorded | MG MAGNESIUM ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；277 K；8% Peg 8000, 50 mM Hepes, 1 mM DTT, pH 7.5, microbatch, temperature 277K
|
Resolution 2.15 Å R-free 0.286 |
| 1G8X STRUCTURE OF A GENETICALLY ENGINEERED MOLECULAR MOTOR Deposited 2000-11-21 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–761（761 aa）
Fragment：MYOSIN II HEAVY CHAIN, MOTOR DOMAIN RESIDUES 1-761, AND ALPHA-ACTININ 3, REPEATS 1 AND 2 RESIDUES 765-1002
Chain B
1–761（761 aa）
Fragment：MYOSIN II HEAVY CHAIN, MOTOR DOMAIN RESIDUES 1-761, AND ALPHA-ACTININ 3, REPEATS 1 AND 2 RESIDUES 765-1002
|
Mutation：ARG238GLU Mutation：ARG238GLU | MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.2；280 K；12% PEGM 5000; 170 mM NaCl; 50 mM HEPES (NaOH) pH 7.2; 5 mM MgCl2; 5 mM DTT; 0.5 mM EGTA; and 2% 2-methyl-1,3-propanediol, at 280 K, VAPOR DIFFUSION, SITTING DROP
|
Resolution 2.80 Å R-free 0.290 |
| 1JWY CRYSTAL STRUCTURE OF THE DYNAMIN A GTPASE DOMAIN COMPLEXED WITH GDP, DETERMINED AS MYOSIN FUSION Deposited 2001-09-05 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
3–765（763 aa）
Fragment：catalytic domain
|
Not recorded | BGC beta-D-glucopyranose × 1 MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, Tris, potassium chloride, magnesium chloride, glucose, methyl-propane-diol, dithiothreitol, EGTA, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.30 Å R-free 0.257 |
| 1JX2 CRYSTAL STRUCTURE OF THE NUCLEOTIDE-FREE DYNAMIN A GTPASE DOMAIN, DETERMINED AS MYOSIN FUSION Deposited 2001-09-05 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
3–765（763 aa）
Fragment：catalytic domain
|
Not recorded | BGC beta-D-glucopyranose × 1 MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, Tris, potassium chloride, magnesium chloride, glucose, methyl-propane-diol, dithiothreitol, EGTA, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.30 Å R-free 0.255 |
| 1LVK X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O-(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN Deposited 1997-09-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 MNT 2'(3')-O-N-METHYLANTHRANILOYL-ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 1.90 Å |
| 1MMA X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN Deposited 1997-07-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；pH 7.0
|
Resolution 2.10 Å |
| 1MMD TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 Deposited 1995-03-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1MMG X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN Deposited 1997-07-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；pH 7.0
|
Resolution 2.10 Å |
| 1MMN X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN Deposited 1997-07-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；pH 7.0
|
Resolution 2.10 Å |
| 1MND TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-ALF4 Deposited 1995-04-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 ALF TETRAFLUOROALUMINATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.60 Å |
| 1MNE TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MG-PYROPHOSPHATE Deposited 1995-04-20 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN
|
Mutation：Q760L, R761P, I762N | MG MAGNESIUM ION × 1 POP PYROPHOSPHATE 2- × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.70 Å |
| 1VOM COMPLEX BETWEEN DICTYOSTELIUM MYOSIN AND MGADP AND VANADATE AT 1.9A RESOLUTION Deposited 1995-11-09 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：TRUNCATED AT RESIDUE 762
|
Not recorded | MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 1.90 Å |
| 1W9I Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx Deposited 2004-10-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN, RESIDUES 1-754
|
Mutation：YES | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 EDO 1,2-ETHANEDIOL × 15 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；10% PEG 8000, 50 MM HEPES PH 7.0, 100 MM NACL, 2 MM DTT, 2 MM NAN3 IN THE RESERVOIR AND 7% PEG 8000, 50 MM HEPES PH 7.0, 100 MM NACL, 2 MM DTT, 2 MM NAN3 IN THE DROP
|
Resolution 1.75 Å R-free 0.207 |
| 1W9J Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-AlF4 Deposited 2004-10-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–758（758 aa）
Fragment：MOTOR DOMAIN, RESIDUES 1-755
|
Mutation：YES | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ALF TETRAFLUOROALUMINATE ION × 1 EDO 1,2-ETHANEDIOL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；12% PEG 8000, 50 MM HEPES PH 7, 100 MM NACL, 2 MM DTT, 2 MM NAN3
|
Resolution 2.00 Å R-free 0.225 |
| 1W9K Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx Deposited 2004-10-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN, RESIDUES 1-759
|
Mutation：YES | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 EDO 1,2-ETHANEDIOL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；10% PEG 8000, 50 MM HEPES PH 7, 100 MM NACL, 2 MM DTT, 2 MM NAN3 BY MICROSEEDING
|
Resolution 2.05 Å R-free 0.232 |
| 1W9L Myosin II Dictyostelium discoideum motor domain S456E bound with MgADP-AlF4 Deposited 2004-10-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–759（759 aa）
Fragment：MOTOR DOMAIN, RESIDUES 1-759
|
Mutation：YES | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ALF TETRAFLUOROALUMINATE ION × 1 EDO 1,2-ETHANEDIOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；12% PEG 8000, 50 MM HEPES PH 7, 100 MM NACL, 2 MM DTT, 2 MM NAN3
|
Resolution 1.95 Å R-free 0.225 |
| 1YV3 The structural basis of blebbistatin inhibition and specificity for myosin II Deposited 2005-02-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–762（762 aa）
|
Not recorded | MG MAGNESIUM ION × 2 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BIT (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；100 mM MOPS (pH 7.0), 250 mM MgCl2, 11% PEG 8000, 1 mM TCEP, 2 mM Thymol, 1 mM MgCl2, 2 mM ADP, and 3 mM sodium vanadate, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 2.00 Å R-free 0.215 |
| 2AKA Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus Deposited 2005-08-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain A
2–765（764 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；Tris, PEG 8000, MPD, DTT, magnesium chloride, pH 8.00, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.90 Å R-free 0.224 |
| 2JHR Crystal structure of myosin-2 motor domain in complex with ADP- metavanadate and pentabromopseudilin Deposited 2008-03-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
Fragment：MOTOR-DOMAIN, RESIDUES 2-761
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 PBQ PENTABROMOPSEUDILIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.4；50 MM HEPES PH 7.4, 140 MM NACL, 11% W/V PEG8000, 2% (V/V) MPD, 5 MM MGCL2, 5 MM DTT, 1 MM EGTA.
|
Resolution 2.80 Å R-free 0.265 |
| 2JJ9 Crystal structure of myosin-2 in complex with ADP-metavanadate Deposited 2008-03-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
Fragment：MOTOR-DOMAIN, RESIDUES 2-761
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.4；50 MM HEPES PH 7.4, 140 MM NACL, 11% W/V PEG8000, 2% (V/V) MPD, 5 MM MGCL2, 5 MM DTT, 1 MM EGTA
|
Resolution 2.30 Å R-free 0.275 |
| 2X9H CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE Deposited 2010-03-19 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–696（695 aa）
Fragment：MYOSIN MOTOR DOMAIN, RESIDUES 2-696
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 KI9 2,3,4,6,8-PENTACHLORO-9H-CARBAZOL-1-OL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.4；50 MM TRIS-HCL PH 7.4, 140 MM NACL, 9% W/V PEG8000, 2% (V/V) MPD, 5 MM MGCL2, 5 MM DTT, 1 MM EGTA
|
Resolution 2.70 Å R-free 0.289 |
| 2XEL Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity Deposited 2010-05-16 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
Fragment：MOTOR DOMAIN, RESUDES 2-761
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 IA2 2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
50 MM HEPES PH 7.4, 140 MM NACL, 11% W/V PEG8000, 2% (V/V) MPD, 5 MM MGCL2, 5 MM DTT, 1 MM EGTA.
|
Resolution 2.50 Å R-free 0.253 |
| 2XO8 Crystal Structure of Myosin-2 in Complex with Tribromodichloropseudilin Deposited 2010-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
3–761（759 aa）
Fragment：MOTOR DOMAIN, RESIDUES 3-761
|
Not recorded | H70 2,4-DICHLORO-6-(3,4,5-TRIBROMO-1H-PYRROL-2-YL)PHENOL × 1 AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.8；50 MM HEPES(PH 6.8), 110 MM NACL, 11% PEG 5K-MME, 2% MPD, 5MM DTT, 1MM EGTA,5MM MGCL2
|
Resolution 2.40 Å R-free 0.254 |
| 2Y0R Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 Deposited 2010-12-07 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
Fragment：MOTOR DOMAIN, RESIDUES 2-759
|
Mutation：YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；100 MM MES (PH 6.5), 25% PEG 8000.
|
Resolution 2.85 Å R-free 0.301 |
| 2Y8I Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 Deposited 2011-02-07 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
Fragment：MOTOR DOMAIN, RESIDUES 2-759
|
Mutation：YES | ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；13% PEG 6000, 4% GLYCEROL., pH 7.0
|
Resolution 3.13 Å R-free 0.337 |
| 2Y9E Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 Deposited 2011-02-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
Fragment：MOTOR DOMAIN, RESIDUES 2-759
|
Mutation：YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；100 MM HEPES (PH 7.5), 20% PEG10000
|
Resolution 3.40 Å R-free 0.372 |
| 3BZ7 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：motor domain, myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 2 VO4 VANADATE ION × 1 BL4 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.00 Å R-free 0.223 |
| 3BZ7 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：motor domain, myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 4 VO4 VANADATE ION × 2 BL4 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.00 Å R-free 0.223 |
| 3BZ8 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：Motor domain, Myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 2 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 EDO 1,2-ETHANEDIOL × 1 BL6 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.20 Å R-free 0.245 |
| 3BZ8 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：Motor domain, Myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 4 VO4 VANADATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 EDO 1,2-ETHANEDIOL × 2 BL6 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.20 Å R-free 0.245 |
| 3BZ9 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：Motor domain, Myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 2 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BL7 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.10 Å R-free 0.238 |
| 3BZ9 Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II Deposited 2008-01-17 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–759（758 aa）
Fragment：Motor domain, Myosine head-like domain
|
Not recorded | MG MAGNESIUM ION × 4 VO4 VANADATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 BL7 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；278 K；mixing 5 ul of protein with an equal volume of well solution containing
100 mM MOPS, 250 mM MgCl2, 12% PEG 8000, 1 mM TCEP, and 2 mM Thymol, pH 7.0, vapor diffusion, hanging drop, temperature 278K
|
Resolution 2.10 Å R-free 0.238 |
| 3MJX Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin Deposited 2010-04-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 BIT (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.4；277 K；50 MM HEPES PH 7.4, 140 MM NACL, 11% W/V PEG8000, 2% (V/V) MPD, 5 MM MGCL2, 5 MM DTT, 1 MM EGTA, 4mM ADP, 4mM meta-vanadate, 0.2 mM blebbistatin., VAPOR DIFFUSION, temperature 277K
|
Resolution 2.20 Å R-free 0.226 |
| 3MKD Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate Deposited 2010-04-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–693（692 aa）
Fragment：Myosin-2 motor domain, UNP residues 2-693
|
Mutation：S456Y | MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；278 K；50mM HEPES, 140mM sodium chloride, 11%(w/v) PEG 5000, 5mM magnesium chloride, 5mM DTT, 1mM EGTA, 2%(v/v) MPD, pH 7.4, VAPOR DIFFUSION, SITTING DROP, temperature 278K
|
Resolution 2.40 Å R-free 0.240 |
| 3MNQ Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol Deposited 2010-04-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
3–761（759 aa）
Fragment：motor domain, residues 3-761
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 STL RESVERATROL × 1 EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.6；277 K；50mM Tris 7.6, 9% PEG 5000 MME, 140mM NaCl, 2% MPD, 5mM MgCl2, 5mM DTT, 1mM EGTA, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.250 |
| 3MYH Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 Deposited 2010-05-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
|
Mutation：S236A | MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BIT (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；12% PEG8K, 250mM MgCl2, 100mM MOPS, 2mM ADP, 3mM sodium vanadate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.01 Å R-free 0.240 |
| 3MYK Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 Deposited 2010-05-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
|
Mutation：S236A | BIT (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE × 1 MG MAGNESIUM ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；12% PEG8K, 250mM MgCl2, 100mM MOPS, 2mM AMPPNP, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.84 Å R-free 0.230 |
| 3MYL Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 Deposited 2010-05-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain X
2–759（758 aa）
|
Mutation：S236A | MG MAGNESIUM ION × 1 POP PYROPHOSPHATE 2- × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；12.5% MePEG5K, 117mM ammonium acetate, 100mM Hepps, 2mM MgCl2, 2mM sodium pyrophosphate , pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.00 Å R-free 0.244 |
| 4AE3 Crystal structure of ammosamide 272:myosin-2 motor domain complex Deposited 2012-01-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
Fragment：MOTOR DOMAIN, RESIDUES 2-761
|
Not recorded | AOV ADP ORTHOVANADATE × 1 MG MAGNESIUM ION × 1 27X AMMOSAMIDE 272 × 2 EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
50 MM HEPES PH 7.6, 140 MM NACL, 11% W/V PEG5K-MME, 2% (V/V) MPD
|
Resolution 2.50 Å R-free 0.254 |
| 4PJK Dicty myosin II R238E.E459R mutant (with ADP.Pi) in the Pi release state Deposited 2014-05-12 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: Monomeric（1） Consistent with protein count |
Chain A
1–761（761 aa）
|
Mutation：R238E, E459R | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 PO4 PHOSPHATE ION × 2 GOL GLYCEROL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；11,25% PEG8k, 100mM MOPS pH 7,5, 1mM TCEP, 250mM MgCl2, 50mM NaH2PO4
|
Resolution 2.15 Å R-free 0.213 |
| 6Z2S Crystal structure of adhibin analogue-bound myosin-2 Deposited 2020-05-18 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
|
Not recorded | MG MAGNESIUM ION × 1 Q5Q 3,6-dibromo-1-(hydroxymethyl)carbazole × 1 AD9 ADP METAVANADATE × 1 ACT ACETATE ION × 3 GOL GLYCEROL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；277 K；0.2 M lithium acetate and 20 % PEG 3350
|
Resolution 3.20 Å R-free 0.262 |
| 6Z7T Nucleotide-free Myosin-II motor domain Deposited 2020-06-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
|
Not recorded | MG MAGNESIUM ION × 2 EDO 1,2-ETHANEDIOL × 10 GOL GLYCEROL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；100 mM HEPES, pH7.5, 10% PEG8000, 8% Ethylenglycol
|
Resolution 1.88 Å R-free 0.217 |
| 6Z7T Nucleotide-free Myosin-II motor domain Deposited 2020-06-01 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–761（760 aa）
|
Not recorded | MG MAGNESIUM ION × 2 EDO 1,2-ETHANEDIOL × 10 GOL GLYCEROL × 5 PGE TRIETHYLENE GLYCOL × 1 PEG DI(HYDROXYETHYL)ETHER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；100 mM HEPES, pH7.5, 10% PEG8000, 8% Ethylenglycol
|
Resolution 1.88 Å R-free 0.217 |
| 6Z7U Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation Deposited 2020-06-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 9 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BIT (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.1 M HEPES, pH7.5, 10% PEG8000, 8% ethylene glycol
|
Resolution 2.58 Å R-free 0.231 |
| 7B19 Mutant Myosin-II-GGG motor domain Deposited 2020-11-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–646（645 aa）
Chain A
649–761（113 aa）
|
Not recorded | AD9 ADP METAVANADATE × 1 MG MAGNESIUM ION × 1 GOL GLYCEROL × 6 GLC alpha-D-glucopyranose × 1 MLI MALONATE ION × 5 PEG DI(HYDROXYETHYL)ETHER × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.24 M sodium malonate, pH8.0, 27% PEG 3350
|
Resolution 2.55 Å R-free 0.252 |
| 7B1A Myosin-II-AA mutant motor domain Deposited 2020-11-24 | Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–761（760 aa）
|
Not recorded | MG MAGNESIUM ION × 1 EDO 1,2-ETHANEDIOL × 3 MLI MALONATE ION × 1 AD9 ADP METAVANADATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；0.24 M sodium malonate pH6.5, 21% PEG 3350
|
Resolution 2.60 Å R-free 0.263 |