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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P0A6X3 New Search
15PDB entries
19Biological assembly
85chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1HK9 Crystal structure of the Hfq protein from Escherichia coli Deposited 2003-03-06 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–72（72 aa） Fragment：RESIDUES 1-72
Chain B 1–72（72 aa） Fragment：RESIDUES 1-72
Chain C 1–72（72 aa） Fragment：RESIDUES 1-72
Chain D 1–72（72 aa） Fragment：RESIDUES 1-72
Chain E 1–72（72 aa） Fragment：RESIDUES 1-72
Chain F 1–72（72 aa） Fragment：RESIDUES 1-72
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；CRYSTALS WERE OBTAINED BY VAPOR DIFFUSION IN 2UL SITTING DROPS. THE RESERVOIR CONTAINED 25% PEG 4000, 0.2 M NH4-ACETATE AND 0.2 M NA-ACETATE PH 4.6. CRYSTALLIZATION WERE CARRIED OUT AT 20C.
Resolution 2.15 Å R-free 0.262
2Y90 Crystal structure of Hfq riboregulator from E. coli (P6 space group) Deposited 2011-02-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–102（102 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；CRYSTALS WERE OBTAINED BY VAPOR DIFFUSION IN 2UL HANGING DROPS AT 20C. THE RESERVOIR CONTAINED 1.6 M AMMONIUM SULFATE, 0.1 M TRIS-HCL PH 8.0.
Resolution 2.25 Å R-free 0.226
2YHT Crystal structure of Hfq riboregulator from E. coli (P1 space group) Deposited 2011-05-06 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain B 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain C 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain D 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain E 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain F 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.4；293 K；CRYSTALS WERE OBTAINED BY VAPOR DIFFUSION IN 2UL SITTING DROPS. THE RESERVOIR CONTAINED 30% PEG 3350, 0.1 M NA-CITRATE PH 5.4. CRYSTALLIZATIONS WERE CARRIED OUT AT 20 DEGREES CELSIUS.
Resolution 2.90 Å R-free 0.229
2YHT Crystal structure of Hfq riboregulator from E. coli (P1 space group) Deposited 2011-05-06 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain G 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain H 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain I 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain J 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain K 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Chain L 1–72（72 aa） Fragment：SM-LIKE FOLD, RESIDUES 1-72
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.4；293 K；CRYSTALS WERE OBTAINED BY VAPOR DIFFUSION IN 2UL SITTING DROPS. THE RESERVOIR CONTAINED 30% PEG 3350, 0.1 M NA-CITRATE PH 5.4. CRYSTALLIZATIONS WERE CARRIED OUT AT 20 DEGREES CELSIUS.
Resolution 2.90 Å R-free 0.229
3GIB Crystal Structure of the Complex of the E. coli Hfq with Poly(A) Deposited 2009-03-05 Assembly 1 Protein–RNA Homooligomer；Protein × 6 PDB declaration: octameric（8） Consistent with all polymers
Chain A 2–69（68 aa） Fragment：N-terminal fragment (2-69)
Chain B 2–69（68 aa） Fragment：N-terminal fragment (2-69)
Chain C 2–69（68 aa） Fragment：N-terminal fragment (2-69)
Not recorded NHE 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID × 6 X-RAY DIFFRACTION
X-ray crystallization conditions pH 9.5；298 K；40% MPD, 0.1 M CHES 9.5, hanging drop, temperature 298K
Resolution 2.40 Å R-free 0.259
3QHS Crystal structure of full-length Hfq from Escherichia coli Deposited 2011-01-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–102（102 aa）
Chain B 1–102（102 aa）
Chain C 1–102（102 aa）
Chain D 1–102（102 aa）
Chain E 1–102（102 aa）
Chain F 1–102（102 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；30% v/v PEG 550 MME, 0.05M calcium chloride dihydrate, 0.1M BIS-TRIS, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.85 Å R-free 0.250
3QHS Crystal structure of full-length Hfq from Escherichia coli Deposited 2011-01-26 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain G 1–102（102 aa）
Chain H 1–102（102 aa）
Chain I 1–102（102 aa）
Chain J 1–102（102 aa）
Chain K 1–102（102 aa）
Chain L 1–102（102 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；30% v/v PEG 550 MME, 0.05M calcium chloride dihydrate, 0.1M BIS-TRIS, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.85 Å R-free 0.250
3QO3 Crystal structure of Escherichia coli Hfq, in complex with ATP Deposited 2011-02-09 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Chain B 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Chain C 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Chain D 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Chain E 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Chain F 1–65（65 aa） Fragment：N-terminal (L)Sm core-domain, UNP residues 1-65
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；0.1M Hepes, 10% (W/V) PEG 8000, 8% (V/V) Ethylene glycol, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 2.15 Å R-free 0.257
3VU3 Crystal structure of the Hfq and catalase HPII complex Deposited 2012-06-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 28 PDB declaration: 28-meric（28） Consistent with protein count
Chain C 1–102（102 aa）
Chain D 1–102（102 aa）
Chain E 1–102（102 aa）
Chain F 1–102（102 aa）
Chain G 1–102（102 aa）
Chain H 1–102（102 aa）
Not recorded HEM PROTOPORPHYRIN IX CONTAINING FE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；293 K；0.1M Tris-HCl, 0.18M NaCl, 10% PEG4000, pH 9.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.85 Å R-free 0.246
4JRI Crystal Structure of Escherichia coli Hfq Proximal Edge Mutant Deposited 2013-03-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 2–69（68 aa） Fragment：UNP residues 2-69
Chain B 2–69（68 aa） Fragment：UNP residues 2-69
Mutation：F39W Mutation：F39W No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.83 Å R-free 0.257
4JRI Crystal Structure of Escherichia coli Hfq Proximal Edge Mutant Deposited 2013-03-21 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain C 2–69（68 aa） Fragment：UNP residues 2-69
Chain D 2–69（68 aa） Fragment：UNP residues 2-69
Mutation：F39W Mutation：F39W No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.83 Å R-free 0.257
4JRK Crystal Structure of Escherichia coli Hfq Surface Mutant Deposited 2013-03-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 2–69（68 aa） Fragment：UNP residues 2-69
Chain B 2–69（68 aa） Fragment：UNP residues 2-69
Chain C 2–69（68 aa） Fragment：UNP residues 2-69
Mutation：F11W Mutation：F11W Mutation：F11W No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.89 Å R-free 0.216
4JUV Crystal Structure of Escherichia coli Hfq Distal Face 1 Mutant Deposited 2013-03-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 2–69（68 aa）
Chain B 2–69（68 aa）
Chain C 2–69（68 aa）
Chain D 2–69（68 aa）
Chain E 2–69（68 aa）
Chain F 2–69（68 aa）
Mutation：Y25W Mutation：Y25W Mutation：Y25W Mutation：Y25W Mutation：Y25W Mutation：Y25W No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.19 Å
4RCB Crystal structure of E Coli Hfq Deposited 2014-09-15 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 5–71（67 aa） Fragment：UNP RESIDUES 5-71
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；0.5M Lithium chloride, 1.6M Ammonium sulfate , VAPOR DIFFUSION, SITTING DROP
Resolution 1.63 Å R-free 0.248
4RCC Crystal structure of E Coli Hfq Deposited 2014-09-15 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 5–71（67 aa） Fragment：UNP RESIDUES 5-71
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；0.1M TRIS.HCl pH 8.5, 1.5M Ammonium sulfate, 15 %(w/v) Glycerol, VAPOR DIFFUSION, SITTING DROP
Resolution 1.98 Å R-free 0.213
4V2S Crystal structure of Hfq in complex with the sRNA RydC Deposited 2014-10-14 Assembly 1 Protein–RNA Homooligomer；Protein × 6 PDB declaration: heptameric（7） Consistent with all polymers
Chain A 1–102（102 aa）
Chain B 1–102（102 aa）
Chain C 1–102（102 aa）
Chain D 1–102（102 aa）
Chain E 1–102（102 aa）
Chain F 1–102（102 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；0.2 M TRI-SODIUM CITRATE, 0.1 M SODIUM CACODYLATE (PH 6.5), 15% ISOPROPANOL
Resolution 3.48 Å R-free 0.282
9GU5 Crystal Structure of Hfq V22A Deposited 2024-09-18 Assembly 1 Protein–RNA Homooligomer；Protein × 6 PDB declaration: heptameric（7） Consistent with all polymers
Chain A 1–102（102 aa）
Chain B 1–102（102 aa）
Chain C 1–102（102 aa）
Chain D 1–102（102 aa）
Chain E 1–102（102 aa）
Chain F 1–102（102 aa）
Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；22.5 %v/v PEGSB, 0.2 M LiSO4, 0.05 M Zn Acet, 0.1 M BIS-TRIS
Resolution 2.90 Å R-free 0.387
9GU5 Crystal Structure of Hfq V22A Deposited 2024-09-18 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain G 1–102（102 aa）
Chain H 1–102（102 aa）
Chain I 1–102（102 aa）
Chain J 1–102（102 aa）
Chain K 1–102（102 aa）
Chain L 1–102（102 aa）
Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A Mutation：V22A MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；22.5 %v/v PEGSB, 0.2 M LiSO4, 0.05 M Zn Acet, 0.1 M BIS-TRIS
Resolution 2.90 Å R-free 0.387
9H45 Crystal Structure of Hfq V22A Deposited 2024-10-17 Assembly 1 Protein–RNA Homooligomer；Protein × 6 PDB declaration: heptameric（7） Consistent with all polymers
Chain A 1–102（102 aa）
Chain B 1–102（102 aa）
Chain C 1–102（102 aa）
Chain D 1–102（102 aa）
Chain E 1–102（102 aa）
Chain F 1–102（102 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；15 %v/v PEGSH 0.15 M NH4 Acet 0.1 M Na3 Cit
Resolution 2.08 Å R-free 0.323

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.