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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P19614 New Search
35PDB entries
39Biological assembly
39chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1AME CRYSTAL STRUCTURE OF TYPE III ANTIFREEZE PROTEIN AT 4 C Deposited 1997-06-13 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–63（63 aa）
Mutation：INS(0), P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.5；277 K；53% AMMONIUM SULFATE 100 MM SODIUM ACETATE PH 4.5 CRYSTALLIZED AT 4 DEGREES C, temperature 277K
Resolution 1.65 Å R-free 0.282
1B7I TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 K61R Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：K61R, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.65 Å R-free 0.238
1B7J TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 V20A Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：V20A, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.65 Å R-free 0.215
1B7K TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 R47H Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：R47H, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.50 Å R-free 0.256
1EKL TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 E35K Deposited 1999-01-21 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：E35K, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.65 Å R-free 0.223
1GZI CRYSTAL STRUCTURE OF TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT, AT 1.8 ANGSTROM RESOLUTION Deposited 1996-10-25 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–66（66 aa）
Mutation：P64A, P65A, DEL(A66) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.6；50% AMMONIUM SULFATE, 0.1M SODIUM ACETATE, PH 5.6
Resolution 1.80 Å R-free 0.233
1HG7 High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus Deposited 2000-12-13 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：YES SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.6；50% AMMONIUM SULFATE, 0.1M SODIUM ACETATE, PH 4.6
Resolution 1.15 Å R-free 0.169
1JAB TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18S Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T18S, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.65 Å R-free 0.217
1KDE NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, 22 STRUCTURES Deposited 1996-07-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：INS(M0), P64A, P65A, INS(K66, D67, E68, L69) No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.6；298 K
Resolution not provided
1KDF NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-07-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：INS(M0), P64A, P65A, INS(K66, D67, E68, L69) No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.6；298 K
Resolution not provided
1MSI STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12) Deposited 1996-10-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–66（65 aa）
Mutation：P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.25 Å R-free 0.225
1MSJ TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15V Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T15V, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.30 Å R-free 0.310
2AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14Q Deposited 1999-01-18 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：N14Q, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.00 Å R-free 0.261
2JIA TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 K61I Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：K61I, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.60 Å R-free 0.259
2MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-16 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16M No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.261
2MSJ TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N46S Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：N46S, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.90 Å R-free 0.326
2SPG TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15S Deposited 1999-01-21 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T15S, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.75 Å R-free 0.249
3AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Q9TQ44T Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：Q9T, Q44T, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.30 Å R-free 0.299
3MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16H No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.43 Å R-free 0.287
3QF6 Neutron structure of type-III Antifreeze Protein allows the reconstruction of AFP-ice interface Deposited 2011-01-21 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–66（66 aa）
Not recorded No recorded non-water small molecule NEUTRON DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.8；285 K；2.2M ammonium sulfate, 9% d8-glycerol, 50mM sodium acetate, pD 5.2, pH 4.8, VAPOR DIFFUSION, SITTING DROP, temperature 285K
Resolution 1.85 Å R-free 0.216
4AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18A Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T18A, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.05 Å R-free 0.238
4MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-16 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16T No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.5；PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.60 Å R-free 0.199
4NY6 Neutron structure of leucine and valine methyl protonated type III antifreeze Deposited 2013-12-10 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–63（63 aa）
Not recorded No recorded non-water small molecule Not declared
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.2；285 K；10mg/ml protein in 50 mM sodium acetate pD 5.2. Drops containing 20 ml protein solution and 30 ml precipitant buffer (2.1 M ammonium sulfate, 9% d8-glycerol) were equilibrated against 1 ml precipitant buffer in the reservoir, VAPOR DIFFUSION, SITTING DROP, temperature 285K
Resolution not provided
5C7R Revealing surface waters on an antifreeze protein by fusion protein crystallography Deposited 2015-06-24 Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–63（63 aa） Fragment：UNP P0AEY0 residues 27-384, UNP P19614 residues 1-63
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；298 K；1.75 M (NH4)2SO4, 100 mM NaOAC (pH 4.4)
Resolution 1.94 Å R-free 0.234
5C7R Revealing surface waters on an antifreeze protein by fusion protein crystallography Deposited 2015-06-24 Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–63（63 aa） Fragment：UNP P0AEY0 residues 27-384, UNP P19614 residues 1-63
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；298 K；1.75 M (NH4)2SO4, 100 mM NaOAC (pH 4.4)
Resolution 1.94 Å R-free 0.234
5MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.5；PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.60 Å R-free 0.199
6AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 M21A Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：M21A, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.10 Å R-free 0.237
6MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.5；PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.65 Å
7AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15A Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T15A, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.70 Å R-free 0.237
7MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 Deposited 1997-09-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Mutation：A16Y No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.5；PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.70 Å R-free 0.207
7Q3V Re-refined structure of a type III antifreeze protein isoform HPLC 12 Deposited 2021-10-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2–63（62 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.194
7Q3V Re-refined structure of a type III antifreeze protein isoform HPLC 12 Deposited 2021-10-28 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 2–63（62 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.194
7Q3V Re-refined structure of a type III antifreeze protein isoform HPLC 12 Deposited 2021-10-28 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 2–63（62 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.194
7Q3V Re-refined structure of a type III antifreeze protein isoform HPLC 12 Deposited 2021-10-28 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 2–63（62 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.194
8AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14SA16H Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：N14S, A16H, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.90 Å R-free 0.260
8MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14SQ44T Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：N14S, Q44T, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.60 Å R-free 0.268
9AME TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 S42G Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：S42G, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 1.80 Å R-free 0.269
9CBE Structure of a type III antifreeze protein isoform HPLC12 re-refined using standard protocols Deposited 2024-06-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–63（63 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions PROTEIN WAS CRYSTALLIZED IN 50-55% AMMONIUM SULFATE, 0.1 M SODIUM ACETATE PH 4-4.5
Resolution 1.90 Å R-free 0.189
9MSI TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18N Deposited 1999-01-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–65（65 aa）
Mutation：T18N, P64A, P65A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.60 Å R-free 0.244

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.