Current Protein Identity:P24280
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1AUA PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P FROM SACCHAROMYCES CEREVISIAE Deposited 1997-08-20 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
3–298(296 aa)
|
Not recorded | BOG octyl beta-D-glucopyranoside × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.2;3% PEG 3350, 1% N-OCTYL B-D-GLUCOPYRANOSIDE, 10 MM HEPES, 150MM KCL, PH 7.2
|
Resolution 2.50 Å R-free 0.273 |
| 6F0E Structure of yeast Sec14p with a picolinamide compound Deposited 2017-11-20 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–304(304 aa)
|
Not recorded | C8K ~{N}-(1,3-benzodioxol-5-ylmethyl)-5-bromanyl-3-fluoranyl-pyridine-2-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;129.5 mM sodium acetate, 64.8 mM TRIS, 10 % (w/v) PEG 4000, 20 % (v/v) glycerol, pH 7.0
|
Resolution 2.60 Å R-free 0.226 |
| 7ZG9 Structure of yeast Sec14p with himbacine Deposited 2022-04-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
3–301(299 aa)
|
Not recorded | KO0 Himbacine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol, pH 7.0
|
Resolution 1.76 Å R-free 0.222 |
| 7ZG9 Structure of yeast Sec14p with himbacine Deposited 2022-04-03 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
3–301(299 aa)
|
Not recorded | KO0 Himbacine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol, pH 7.0
|
Resolution 1.76 Å R-free 0.222 |
| 7ZGA Structure of yeast Sec14p with ergoline Deposited 2022-04-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
3–298(296 aa)
|
Not recorded | IUF ~{O}9-methyl ~{O}4-[2,2,2-tris(chloranyl)ethyl] (5~{a}~{S},6~{a}~{S},9~{R},10~{a}~{S})-7-methyl-3-nitro-5,5~{a},6,6~{a},8,9,10,10~{a}-octahydroindolo[4,3-fg]quinoline-4,9-dicarboxylate × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol adjusted to pH 7.0
|
Resolution 2.30 Å R-free 0.228 |
| 7ZGB Structure of yeast Sec14p with NPPM112 Deposited 2022-04-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
4–299(296 aa)
|
Not recorded | IUJ 4-fluoranyl-~{N}-[(4-pyrrolidin-1-ylphenyl)methyl]benzamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol adjusted to pH 7.0
|
Resolution 2.70 Å R-free 0.249 |
| 7ZGC Structure of yeast Sec14p with NPPM481 Deposited 2022-04-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–304(304 aa)
|
Not recorded | IUO (4-chloranyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone × 1 PO4 PHOSPHATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol adjusted to pH 7.0
|
Resolution 2.24 Å R-free 0.211 |
| 7ZGD Structure of yeast Sec14p with NPPM244 Deposited 2022-04-03 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–304(304 aa)
|
Not recorded | IUC (4-bromanyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;294 K;129,5 mM sodium acetate, 64,8 mM TRIS, 4,6 % (w/v) PEG 4000, and 11.9 % (v/v) glycerol adjusted to pH 7.0
|
Resolution 2.08 Å R-free 0.232 |
| 9EFP Crystal Structure of Saccharomyces cerevisiae Sec14p in complex with phosphatidylcholine Deposited 2024-11-20 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–304(304 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 1 GOL GLYCEROL × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;289.15 K;0.1 M Bis-Tris, 30-40% v/v PEG 400, pH 5.5-pH 6.5
|
Resolution 1.83 Å R-free 0.208 |
| 9EFP Crystal Structure of Saccharomyces cerevisiae Sec14p in complex with phosphatidylcholine Deposited 2024-11-20 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–304(304 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 1 GOL GLYCEROL × 1 PEG DI(HYDROXYETHYL)ETHER × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;289.15 K;0.1 M Bis-Tris, 30-40% v/v PEG 400, pH 5.5-pH 6.5
|
Resolution 1.83 Å R-free 0.208 |
| 9YV3 Crystal Structure of a ternary complex of Saccharomyces cerevisiae Sec14 with a small molecule inhibitor and phosphatidylcholine Deposited 2025-10-23 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
5–302(298 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 1 IUO (4-chloranyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;296 K;0.05 M ammonium sulfate, 0.05 M Bis Tris 30% v/v pentaeritheytolethoxylate (pH 6.5)
|
Resolution 2.25 Å R-free 0.268 |