Current Protein Identity:P41567
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2IF1 HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES Deposited 1998-08-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–113(113 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6;300 K;Ionic strength (raw mmCIF value) 400 mM;Pressure 1
|
Resolution not provided |
| 4KZX Rabbit 40S ribosomal subunit in complex with eIF1. Deposited 2013-05-30 | Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 35-meric(35) Consistent with all polymers |
Chain l
1–113(113 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
|
Resolution 7.81 Å R-free 0.347 |
| 4KZY Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. Deposited 2013-05-30 | Assembly 1 Protein–RNA Heteromer;Protein × 35 PDB declaration: 36-meric(36) Consistent with all polymers |
Chain l
1–113(113 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
|
Resolution 7.01 Å R-free 0.348 |
| 6YBW Structure of a human 48S translational initiation complex - 40S body Deposited 2020-03-18 | Assembly 1 Protein–RNA Heteromer;Protein × 24 PDB declaration: 26-meric(26) Consistent with all polymers |
Chain p
1–113(113 aa)
|
Not recorded | MG MAGNESIUM ION × 60 ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å |
| 6ZMW Structure of a human 48S translational initiation complex Deposited 2020-07-04 | Assembly 1 Protein–RNA Heteromer;Protein × 54 PDB declaration: 57-meric(57) Consistent with all polymers |
Chain p
1–113(113 aa)
|
Not recorded | ZN ZINC ION × 2 MG MAGNESIUM ION × 89 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å |
| 6ZP4 SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 Deposited 2020-07-08 | Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 54-meric(54) Consistent with all polymers |
Chain Z
1–113(113 aa)
|
Not recorded | ZN ZINC ION × 4 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |
| 6ZVJ Structure of a human ABCE1-bound 43S pre-initiation complex - State II Deposited 2020-07-24 | Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 51-meric(51) Consistent with all polymers |
Chain N
23–113(91 aa)
|
Not recorded | ZN ZINC ION × 3 SF4 IRON/SULFUR CLUSTER × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 7A09 Structure of a human ABCE1-bound 43S pre-initiation complex - State III Deposited 2020-08-07 | Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 54-meric(54) Consistent with all polymers |
Chain Z
1–113(113 aa)
|
Not recorded | ZN ZINC ION × 4 SF4 IRON/SULFUR CLUSTER × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MET METHIONINE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å |
| 7QP6 Structure of the human 48S initiation complex in open state (h48S AUG open) Deposited 2022-01-03 | Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 53-meric(53) Consistent with all polymers |
Chain p
1–113(113 aa)
|
Not recorded | ZN ZINC ION × 2 MG MAGNESIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5;20 mM Hepes, pH 7.5,
95 mM KOAc, 3.75 mM Mg(OAc)2, 1 mM ATP, 0.5 mM GTP, 0.25 mM spermidine, 2 mM DTT,
0.4 U/uL RiboLock RNase inhibitor
cryo-EM vitrification conditions
Cryogen ETHANE;Cryo-EM grids were prepared by
floating home-made continuous carbon on 40 ul sample in the wells of teflon block (custom-made). The sample-covered carbon was then adsorbed to an EM grid.
|
Resolution 4.70 Å |
| 8PJ1 Structure of human 48S translation initiation complex in open codon scanning state (48S-1) Deposited 2023-06-22 | Assembly 1 Protein–RNA Heteromer;Protein × 51 PDB declaration: 54-meric(54) Consistent with all polymers |
Chain p
1–113(113 aa)
|
Not recorded | MG MAGNESIUM ION × 90 ZN ZINC ION × 3 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MET METHIONINE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE;Manual blotting & plunge-freezing
|
Resolution 3.40 Å |
| 8PPK Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit Deposited 2023-07-07 | Assembly 1 Protein–RNA Heteromer;Protein × 36 PDB declaration: 37-meric(37) Consistent with all polymers |
Chain p
1–113(113 aa)
|
Not recorded | UNX UNKNOWN LIGAND × 117 MG MAGNESIUM ION × 111 ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.98 Å |
| 8PPL MERS-CoV Nsp1 bound to the human 43S pre-initiation complex Deposited 2023-07-07 | Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 52-meric(52) Consistent with all polymers |
Chain Ip
1–113(113 aa)
|
Not recorded | ZN ZINC ION × 4 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 116 MET METHIONINE × 1 UNX UNKNOWN LIGAND × 129 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.65 Å |
| 8XXN Cryo-EM structure of the human 43S ribosome with PDCD4 Deposited 2024-01-18 | Assembly 1 Protein–RNA Heteromer;Protein × 49 PDB declaration: 50-meric(50) Consistent with all polymers |
Chain C1
1–113(113 aa)
|
Not recorded | MG MAGNESIUM ION × 23 ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 9BLN The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex Deposited 2024-04-30 | Assembly 1 Protein–RNA Heteromer;Protein × 49 PDB declaration: 50-meric(50) Consistent with all polymers |
Chain W
1–113(113 aa)
|
Not recorded | MG MAGNESIUM ION × 88 K POTASSIUM ION × 19 SPD SPERMIDINE × 1 ZN ZINC ION × 3 ACY ACETIC ACID × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 9NPX SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosomal subunit (local refinement of the 40S body) Deposited 2025-03-11 | Assembly 1 Protein–RNA Heteromer;Protein × 23 PDB declaration: 24-meric(24) Consistent with all polymers |
Chain k
1–113(113 aa)
|
Not recorded | MG MAGNESIUM ION × 57 K POTASSIUM ION × 13 ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.10 Å |