Current Protein Identity:P41567 New Search
Main Difference Dimensions in This Set
Different construct Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2IF1 HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES Deposited 1998-08-04 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1–113(113 aa)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6;300 K;Ionic strength (raw mmCIF value) 400 mM;Pressure 1
Resolution not provided
4KZX Rabbit 40S ribosomal subunit in complex with eIF1. Deposited 2013-05-30 Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 35-meric(35) Consistent with all polymers
Chain l 1–113(113 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
Resolution 7.81 Å R-free 0.347
4KZY Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. Deposited 2013-05-30 Assembly 1 Protein–RNA Heteromer;Protein × 35 PDB declaration: 36-meric(36) Consistent with all polymers
Chain l 1–113(113 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
Resolution 7.01 Å R-free 0.348
6YBW Structure of a human 48S translational initiation complex - 40S body Deposited 2020-03-18 Assembly 1 Protein–RNA Heteromer;Protein × 24 PDB declaration: 26-meric(26) Consistent with all polymers
Chain p 1–113(113 aa)
Not recorded MG MAGNESIUM ION × 60 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6ZMW Structure of a human 48S translational initiation complex Deposited 2020-07-04 Assembly 1 Protein–RNA Heteromer;Protein × 54 PDB declaration: 57-meric(57) Consistent with all polymers
Chain p 1–113(113 aa)
Not recorded ZN ZINC ION × 2 MG MAGNESIUM ION × 89 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
6ZP4 SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 Deposited 2020-07-08 Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 54-meric(54) Consistent with all polymers
Chain Z 1–113(113 aa)
Not recorded ZN ZINC ION × 4 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
6ZVJ Structure of a human ABCE1-bound 43S pre-initiation complex - State II Deposited 2020-07-24 Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 51-meric(51) Consistent with all polymers
Chain N 23–113(91 aa)
Not recorded ZN ZINC ION × 3 SF4 IRON/SULFUR CLUSTER × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7A09 Structure of a human ABCE1-bound 43S pre-initiation complex - State III Deposited 2020-08-07 Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 54-meric(54) Consistent with all polymers
Chain Z 1–113(113 aa)
Not recorded ZN ZINC ION × 4 SF4 IRON/SULFUR CLUSTER × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MET METHIONINE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
7QP6 Structure of the human 48S initiation complex in open state (h48S AUG open) Deposited 2022-01-03 Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 53-meric(53) Consistent with all polymers
Chain p 1–113(113 aa)
Not recorded ZN ZINC ION × 2 MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5;20 mM Hepes, pH 7.5, 95 mM KOAc, 3.75 mM Mg(OAc)2, 1 mM ATP, 0.5 mM GTP, 0.25 mM spermidine, 2 mM DTT, 0.4 U/uL RiboLock RNase inhibitor
cryo-EM vitrification conditions Cryogen ETHANE;Cryo-EM grids were prepared by floating home-made continuous carbon on 40 ul sample in the wells of teflon block (custom-made). The sample-covered carbon was then adsorbed to an EM grid.
Resolution 4.70 Å
8PJ1 Structure of human 48S translation initiation complex in open codon scanning state (48S-1) Deposited 2023-06-22 Assembly 1 Protein–RNA Heteromer;Protein × 51 PDB declaration: 54-meric(54) Consistent with all polymers
Chain p 1–113(113 aa)
Not recorded MG MAGNESIUM ION × 90 ZN ZINC ION × 3 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MET METHIONINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE;Manual blotting & plunge-freezing
Resolution 3.40 Å
8PPK Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit Deposited 2023-07-07 Assembly 1 Protein–RNA Heteromer;Protein × 36 PDB declaration: 37-meric(37) Consistent with all polymers
Chain p 1–113(113 aa)
Not recorded UNX UNKNOWN LIGAND × 117 MG MAGNESIUM ION × 111 ZN ZINC ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 2.98 Å
8PPL MERS-CoV Nsp1 bound to the human 43S pre-initiation complex Deposited 2023-07-07 Assembly 1 Protein–RNA Heteromer;Protein × 50 PDB declaration: 52-meric(52) Consistent with all polymers
Chain Ip 1–113(113 aa)
Not recorded ZN ZINC ION × 4 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 116 MET METHIONINE × 1 UNX UNKNOWN LIGAND × 129 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 2.65 Å
8XXN Cryo-EM structure of the human 43S ribosome with PDCD4 Deposited 2024-01-18 Assembly 1 Protein–RNA Heteromer;Protein × 49 PDB declaration: 50-meric(50) Consistent with all polymers
Chain C1 1–113(113 aa)
Not recorded MG MAGNESIUM ION × 23 ZN ZINC ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
9BLN The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex Deposited 2024-04-30 Assembly 1 Protein–RNA Heteromer;Protein × 49 PDB declaration: 50-meric(50) Consistent with all polymers
Chain W 1–113(113 aa)
Not recorded MG MAGNESIUM ION × 88 K POTASSIUM ION × 19 SPD SPERMIDINE × 1 ZN ZINC ION × 3 ACY ACETIC ACID × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.90 Å
9NPX SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosomal subunit (local refinement of the 40S body) Deposited 2025-03-11 Assembly 1 Protein–RNA Heteromer;Protein × 23 PDB declaration: 24-meric(24) Consistent with all polymers
Chain k 1–113(113 aa)
Not recorded MG MAGNESIUM ION × 57 K POTASSIUM ION × 13 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.10 Å