Current Protein Identity：P55265
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1QBJ CRYSTAL STRUCTURE OF THE ZALPHA Z-DNA COMPLEX Deposited 1999-04-22 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
133–209（77 aa）
Fragment：N-TERMINAL HELIX-TURN-HELIX DOMAIN ZALPHA
Chain B
133–209（77 aa）
Fragment：N-TERMINAL HELIX-TURN-HELIX DOMAIN ZALPHA
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.6；HANGING DROP VAPOR DIFFUSION OVER 1.6 M (NH4)2SO4, 10 % GLYCEROL AT 24 DEGREES
CELSIUS, pH 5.6
|
Resolution 2.10 Å R-free 0.265 |
| 1QBJ CRYSTAL STRUCTURE OF THE ZALPHA Z-DNA COMPLEX Deposited 1999-04-22 | Assembly 2 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain C
133–209（77 aa）
Fragment：N-TERMINAL HELIX-TURN-HELIX DOMAIN ZALPHA
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.6；HANGING DROP VAPOR DIFFUSION OVER 1.6 M (NH4)2SO4, 10 % GLYCEROL AT 24 DEGREES
CELSIUS, pH 5.6
|
Resolution 2.10 Å R-free 0.265 |
| 1QGP NMR STRUCTURE OF THE Z-ALPHA DOMAIN OF ADAR1, 15 STRUCTURES Deposited 1999-05-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
125–201（77 aa）
Fragment：Z-ALPHA DOMAIN
|
Mutation：C125S | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5；298 K；Ionic strength (raw mmCIF value) 0.137 M NACL；Pressure 1
NMR sample composition
NA-PHOSPHATE
|
Resolution not provided |
| 1XMK The Crystal structure of the Zb domain from the RNA editing enzyme ADAR1 Deposited 2004-10-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
294–366（73 aa）
|
Not recorded | CD CADMIUM ION × 2 NI NICKEL (II) ION × 1 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 9；312 K；PEG1000, Cadmium Chloride, Nickel Chloride, Tris, pH 9.0, VAPOR DIFFUSION, HANGING DROP, temperature 312K, pH 9.00
|
Resolution 0.97 Å R-free 0.183 |
| 2ACJ Crystal structure of the B/Z junction containing DNA bound to Z-DNA binding proteins Deposited 2005-07-19 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–202（63 aa）
Fragment：Zalpha domain, ADAR1
Chain B
140–202（63 aa）
Fragment：Zalpha domain, ADAR1
Chain C
140–202（63 aa）
Fragment：Zalpha domain, ADAR1
Chain D
140–202（63 aa）
Fragment：Zalpha domain, ADAR1
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；295 K；22-23% MPD, 55-60mM sodium acetate, 15-16mM calsium chloride, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.60 Å R-free 0.285 |
| 2GXB Crystal Structure of The Za Domain bound to Z-RNA Deposited 2006-05-08 | Assembly 1 Protein–RNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
140–202（63 aa）
Fragment：Za Domain
Chain B
140–202（63 aa）
Fragment：Za Domain
|
Not recorded | NA SODIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 3.6；292 K；40% PEG600, 100mM Sodium Acetate, pH 3.6, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.25 Å R-free 0.244 |
| 2L54 Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A) Deposited 2010-10-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
136–198（63 aa）
Fragment：DRADA 1 domain, UNP residues 136-198
|
Mutation：N43A, Y47A | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；298 K；Pressure ambient
NMR sample composition
50 mM sodium phosphate-1, 50 mM sodium chloride-2, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2MDR Solution structure of the third double-stranded RNA-binding domain (dsRBD3) of human adenosine-deaminase ADAR1 Deposited 2013-09-17 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
708–801（94 aa）
Fragment：UNP residues 708-801
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；313 K；Ionic strength (raw mmCIF value) 120；Pressure ambient
NMR sample composition
0.7-0.9 mM [U-99% 13C; U-99% 15N] dsRBD3, 20 mM sodium phosphate, 100 mM potassium chloride, 1 mM DTT, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7-0.9 mM [U-99% 13C; U-99% 15N] dsRBD3, 20 mM sodium phosphate, 100 mM potassium chloride, 1 mM DTT, 100% D2O | 100% D2O
NMR sample composition
0.7-0.9 mM [U-99% 15N] dsRBD3, 20 mM sodium phosphate, 100 mM potassium chloride, 1 mM DTT, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7-0.9 mM dsRBD3, 20 mM sodium phosphate, 100 mM potassium chloride, 1 mM DTT, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 3F21 Crystal structure of Zalpha in complex with d(CACGTG) Deposited 2008-10-28 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
Chain B
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.20 Å R-free 0.279 |
| 3F21 Crystal structure of Zalpha in complex with d(CACGTG) Deposited 2008-10-28 | Assembly 2 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain C
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.20 Å R-free 0.279 |
| 3F22 Crystal structure of Zalpha in complex with d(CGTACG) Deposited 2008-10-28 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
Chain B
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.50 Å R-free 0.269 |
| 3F22 Crystal structure of Zalpha in complex with d(CGTACG) Deposited 2008-10-28 | Assembly 2 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain C
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.50 Å R-free 0.269 |
| 3F23 Crystal structure of Zalpha in complex with d(CGGCCG) Deposited 2008-10-28 | Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
Chain B
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.70 Å R-free 0.264 |
| 3F23 Crystal structure of Zalpha in complex with d(CGGCCG) Deposited 2008-10-28 | Assembly 2 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain C
133–209（77 aa）
Fragment：N-terminal zalpha Domain, UNP residues 133-209
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；2.2M (NH4)2SO4, 10% Glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.70 Å R-free 0.264 |
| 3IRQ Crystal structure of a Z-Z junction Deposited 2009-08-24 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–202（63 aa）
Fragment：Zalpha domain
Chain B
140–202（63 aa）
Fragment：Zalpha domain
Chain C
140–202（63 aa）
Fragment：Zalpha domain
Chain D
140–202（63 aa）
Fragment：Zalpha domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；17% PEG 2000, 0.1 M Tris-HCl, 0.2 M ammonium acetate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.80 Å R-free 0.271 |
| 3IRR Crystal Structure of a Z-Z junction (with HEPES intercalating) Deposited 2009-08-24 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–202（63 aa）
Fragment：Zalpha domain
Chain B
140–202（63 aa）
Fragment：Zalpha domain
Chain C
140–202（63 aa）
Fragment：Zalpha domain
Chain D
140–202（63 aa）
Fragment：Zalpha domain
|
Not recorded | EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；16% PEG 2000 MME, 0.1 M HEPES, 0.2 M ammonium acetate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.65 Å R-free 0.283 |
| 5ZU1 Crystal Structure of BZ junction in diverse sequence Deposited 2018-05-05 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–198（59 aa）
Chain B
140–198（59 aa）
Chain C
140–198（59 aa）
Chain D
140–198（59 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 4.5；296 K；25% 2-methyl-2,4-pentanediol (MPD), 100mM NaOAC, pH 4.5
|
Resolution 3.01 Å R-free 0.280 |
| 5ZUO Crystal Structure of BZ junction in diverse sequence Deposited 2018-05-08 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–202（63 aa）
Chain B
140–202（63 aa）
Chain C
140–202（63 aa）
Chain D
140–202（63 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；296 K；20% dioxane, with microseeding of small crystals
|
Resolution 2.90 Å R-free 0.301 |
| 5ZUP Crystal Structure of BZ junction in diverse sequence Deposited 2018-05-08 | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
140–202（63 aa）
Chain B
140–202（63 aa）
Chain C
140–202（63 aa）
Chain D
140–202（63 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；296 K；25% ethylene glycol, with microseeding of small crystal
|
Resolution 2.90 Å R-free 0.282 |
| 7C0I Crystal structure of chimeric mutant of E3L in complex with Z-DNA Deposited 2020-05-01 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
169–184（16 aa）
Chain A
192–193（2 aa）
Chain A
195–195（1 aa）
Chain B
169–184（16 aa）
Chain B
192–193（2 aa）
Chain B
195–195（1 aa）
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；295 K；Sodium citrate pH 4.0, Ammonium sulfate, ethylene glycol
|
Resolution 2.40 Å R-free 0.227 |
| 7C0I Crystal structure of chimeric mutant of E3L in complex with Z-DNA Deposited 2020-05-01 | Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain C
169–184（16 aa）
Chain C
192–193（2 aa）
Chain C
195–195（1 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；295 K；Sodium citrate pH 4.0, Ammonium sulfate, ethylene glycol
|
Resolution 2.40 Å R-free 0.227 |
| 7C0J Crystal structure of chimeric mutant of GH5 in complex with Z-DNA Deposited 2020-05-01 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain A
169–178（10 aa）
Chain A
192–192（1 aa）
Chain A
195–195（1 aa）
Chain B
169–178（10 aa）
Chain B
192–192（1 aa）
Chain B
195–195（1 aa）
|
Mutation：K41G,S42E,R43G,K53A,R95A Mutation：K41G,S42E,R43G,K53A,R95A Mutation：K41G,S42E,R43G,K53A,R95A Mutation：K41G,S42E,R43G,K53A,R95A Mutation：K41G,S42E,R43G,K53A,R95A Mutation：K41G,S42E,R43G,K53A,R95A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；MES pH 6.0, PEG 4000, ethylene glycol
|
Resolution 2.75 Å R-free 0.248 |
| 7ZJ1 Crystal structure of ADAR1-dsRBD3 dimer Deposited 2022-04-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
716–797（82 aa）
Chain B
716–797（82 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4；293 K；100 mM sodium citrate pH 4.0, 20% (w/v) PEG 6000, and 1.0 M LiCl
|
Resolution 1.65 Å R-free 0.225 |
| 7ZLQ Crystal structure of ADAR1-dsRBD3 dimer in complex with dsRNA Deposited 2022-04-15 | Assembly 1 Protein–RNA Homooligomer；Protein × 2 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
716–797（82 aa）
Chain B
716–797（82 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6；293 K；50 mM sodium cacodylate, 5% (w/v) PEG 4000, 30 mM CaCl2, 230 mM KCl
|
Resolution 2.80 Å R-free 0.266 |
| 8GBC Homo sapiens Zalpha mutant - N173S Deposited 2023-02-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
140–202（63 aa）
|
Mutation：N173S | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.4；277 K；Ionic strength (raw mmCIF value) 100；Pressure 1
NMR sample composition
2 mM [U-13C; U-15N] protein, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 8GBD Homo sapiens Zalpha mutant - P193A Deposited 2023-02-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
140–202（63 aa）
|
Mutation：P193A | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.4；277 K；Ionic strength (raw mmCIF value) 100；Pressure 1
NMR sample composition
2 mM [U-13C; U-15N] protein, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 9B83 Cryo-EM structure of human ADAR1 in complex with dsRNA derived from human GLI1 gene Deposited 2024-03-28 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: trimeric（3） Consistent with all polymers |
Chain A
127–1226（1100 aa）
Chain B
127–1226（1100 aa）
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 2 ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.01 Å |
| 9B84 Cryo-EM structure of human ADAR1 in complex with dsRNA derived from HT2C gene Deposited 2024-03-28 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: trimeric（3） Consistent with all polymers |
Chain A
127–1226（1100 aa）
Chain B
127–1226（1100 aa）
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 2 ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 9B89 Cryo-EM structure of human ADAR1 in complex with dsRNA derived from HT2C gene in the pre-editing state Deposited 2024-03-29 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: trimeric（3） Consistent with all polymers |
Chain A
127–1226（1100 aa）
Chain B
127–1226（1100 aa）
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 2 ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.87 Å |