Current Protein Identity:P55899
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1EXU CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR Deposited 2000-05-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
24–290(267 aa)
Fragment:EXTRACELLULAR LIGAND BINDING DOMAIN
|
Not recorded | BME BETA-MERCAPTOETHANOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.2;295 K;ammonium sulfate, glycerol, tris, pH 8.2, VAPOR DIFFUSION, HANGING DROP, temperature 295.0K
|
Resolution 2.70 Å R-free 0.247 |
| 3M17 Crystal structure of human FcRn with a monomeric peptide inhibitor Deposited 2010-03-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;277 K;2uL protein:peptide with 2ul solution of 100mM sodium phosphate/citric acid, 20% PEG 3350, 8% ethanol, pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.325 |
| 3M17 Crystal structure of human FcRn with a monomeric peptide inhibitor Deposited 2010-03-04 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;277 K;2uL protein:peptide with 2ul solution of 100mM sodium phosphate/citric acid, 20% PEG 3350, 8% ethanol, pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.325 |
| 3M17 Crystal structure of human FcRn with a monomeric peptide inhibitor Deposited 2010-03-04 | Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain E
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;277 K;2uL protein:peptide with 2ul solution of 100mM sodium phosphate/citric acid, 20% PEG 3350, 8% ethanol, pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.325 |
| 3M17 Crystal structure of human FcRn with a monomeric peptide inhibitor Deposited 2010-03-04 | Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain G
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;277 K;2uL protein:peptide with 2ul solution of 100mM sodium phosphate/citric acid, 20% PEG 3350, 8% ethanol, pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 2.60 Å R-free 0.325 |
| 3M1B Crystal structure of human FcRn with a dimeric peptide inhibitor Deposited 2010-03-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;294 K;2ul protein:peptide with 2ul buffer containing 100 mM phosphate/citric acid, 22% PEG 1000 and 8% ethanol , pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 3.10 Å R-free 0.397 |
| 3M1B Crystal structure of human FcRn with a dimeric peptide inhibitor Deposited 2010-03-04 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;294 K;2ul protein:peptide with 2ul buffer containing 100 mM phosphate/citric acid, 22% PEG 1000 and 8% ethanol , pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 3.10 Å R-free 0.397 |
| 3M1B Crystal structure of human FcRn with a dimeric peptide inhibitor Deposited 2010-03-04 | Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain E
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;294 K;2ul protein:peptide with 2ul buffer containing 100 mM phosphate/citric acid, 22% PEG 1000 and 8% ethanol , pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 3.10 Å R-free 0.397 |
| 3M1B Crystal structure of human FcRn with a dimeric peptide inhibitor Deposited 2010-03-04 | Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain G
24–290(267 aa)
Fragment:UNP residues 24-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.2;294 K;2ul protein:peptide with 2ul buffer containing 100 mM phosphate/citric acid, 22% PEG 1000 and 8% ethanol , pH 4.2, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 3.10 Å R-free 0.397 |
| 4K71 Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor Deposited 2013-04-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
24–297(274 aa)
Fragment:UNP residues 24-297
|
Not recorded | SO4 SULFATE ION × 11 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.9;293 K;1.7 M ammonium sulfate, 0.1 M sodium citrate, pH 4.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.255 |
| 4K71 Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor Deposited 2013-04-16 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
24–297(274 aa)
Fragment:UNP residues 24-297
|
Not recorded | SO4 SULFATE ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.9;293 K;1.7 M ammonium sulfate, 0.1 M sodium citrate, pH 4.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.255 |
| 4K71 Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor Deposited 2013-04-16 | Assembly 3 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain B
24–297(274 aa)
Fragment:UNP residues 24-297
Chain E
24–297(274 aa)
Fragment:UNP residues 24-297
|
Not recorded | SO4 SULFATE ION × 38 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 4.9;293 K;1.7 M ammonium sulfate, 0.1 M sodium citrate, pH 4.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.255 |
| 4N0F Human FcRn complexed with human serum albumin Deposited 2013-10-01 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
27–297(271 aa)
Fragment:unp residues 27-297
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 5.2;298 K;4% Tacsimate, pH 4.0, 12% PEG3350, 30 mM Sodium Acetate, pH 5.2, HSA/FcRn 10 mg/ml, VAPOR DIFFUSION, temperature 298K
|
Resolution 3.02 Å R-free 0.260 |
| 4N0F Human FcRn complexed with human serum albumin Deposited 2013-10-01 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain E
27–297(271 aa)
Fragment:unp residues 27-297
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 5.2;298 K;4% Tacsimate, pH 4.0, 12% PEG3350, 30 mM Sodium Acetate, pH 5.2, HSA/FcRn 10 mg/ml, VAPOR DIFFUSION, temperature 298K
|
Resolution 3.02 Å R-free 0.260 |
| 4N0F Human FcRn complexed with human serum albumin Deposited 2013-10-01 | Assembly 3 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain H
27–297(271 aa)
Fragment:unp residues 27-297
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 5.2;298 K;4% Tacsimate, pH 4.0, 12% PEG3350, 30 mM Sodium Acetate, pH 5.2, HSA/FcRn 10 mg/ml, VAPOR DIFFUSION, temperature 298K
|
Resolution 3.02 Å R-free 0.260 |
| 4N0F Human FcRn complexed with human serum albumin Deposited 2013-10-01 | Assembly 4 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain K
27–297(271 aa)
Fragment:unp residues 27-297
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 5.2;298 K;4% Tacsimate, pH 4.0, 12% PEG3350, 30 mM Sodium Acetate, pH 5.2, HSA/FcRn 10 mg/ml, VAPOR DIFFUSION, temperature 298K
|
Resolution 3.02 Å R-free 0.260 |
| 4N0U Ternary complex between Neonatal Fc receptor, serum albumin and Fc Deposited 2013-10-02 | Assembly 1 Other combination Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain A
27–290(264 aa)
Fragment:FcRn, alpha chain, ecd, unp residue 27-290
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 5.2;298 K;4% Tacsimate, pH 4.0, 12% PEG 3350, VAPOR DIFFUSION, temperature 298K
|
Resolution 3.80 Å R-free 0.303 |
| 5BJT Crystal structure of human FcRn with a peptide inhibitor at multiple sites Deposited 2016-10-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
24–290(267 aa)
Fragment:extracellular domain (UNP residues 24-290)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.7;277 K;1.6 M ammonium sulfate, 20% glycerol, 0.8 M sodium acetate
|
Resolution 3.20 Å R-free 0.339 |
| 5BJT Crystal structure of human FcRn with a peptide inhibitor at multiple sites Deposited 2016-10-23 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
24–290(267 aa)
Fragment:extracellular domain (UNP residues 24-290)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.7;277 K;1.6 M ammonium sulfate, 20% glycerol, 0.8 M sodium acetate
|
Resolution 3.20 Å R-free 0.339 |
| 5BJT Crystal structure of human FcRn with a peptide inhibitor at multiple sites Deposited 2016-10-23 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
24–290(267 aa)
Fragment:extracellular domain (UNP residues 24-290)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.7;277 K;1.6 M ammonium sulfate, 20% glycerol, 0.8 M sodium acetate
|
Resolution 3.20 Å R-free 0.339 |
| 5BJT Crystal structure of human FcRn with a peptide inhibitor at multiple sites Deposited 2016-10-23 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
24–290(267 aa)
Fragment:extracellular domain (UNP residues 24-290)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.7;277 K;1.6 M ammonium sulfate, 20% glycerol, 0.8 M sodium acetate
|
Resolution 3.20 Å R-free 0.339 |
| 5BXF Apo FcRn Structure at pH 4.5 Deposited 2015-06-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–290(290 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;298 K;.1M sodium citrate pH 4.5, 20% PEG (4000)
|
Resolution 2.85 Å R-free 0.314 |
| 5BXF Apo FcRn Structure at pH 4.5 Deposited 2015-06-08 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
1–290(290 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;298 K;.1M sodium citrate pH 4.5, 20% PEG (4000)
|
Resolution 2.85 Å R-free 0.314 |
| 5WHK Crystal structure of Fab fragment of antibody DX-2507 bound to FcRn-B2M Deposited 2017-07-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–297(297 aa)
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 NHE 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;289 K;DX-2507 Fab FcRn B2M complex at 6.6 mg/mL at 70 uM against an optimization screen against JCSG+ A7 18% PEG 8000, 0.1 M CHES pH 9.8 with seeding from an earlier crystal obtained under similar conditions, supplemented with 20% ethylene glycol as cro-protectant
|
Resolution 2.50 Å R-free 0.225 |
| 6C97 Crystal structure of FcRn at pH3 Deposited 2018-01-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
24–297(274 aa)
|
Not recorded | GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A
PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.01-3.09 AND 12-16% W/V PEG 6,000.
|
Resolution 2.00 Å R-free 0.210 |
| 6C97 Crystal structure of FcRn at pH3 Deposited 2018-01-25 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A
PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.01-3.09 AND 12-16% W/V PEG 6,000.
|
Resolution 2.00 Å R-free 0.210 |
| 6C98 Crystal structure of FcRn bound to UCB-84 Deposited 2018-01-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
24–297(274 aa)
|
Not recorded | CYS CYSTEINE × 1 ER7 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one × 1 GOL GLYCEROL × 1 PEG DI(HYDROXYETHYL)ETHER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.0 AND 20% W/V PEG 6,000. CRYSTALS OF FCRN WERE SOAKED FOR
THREE DAYS IN BUFFER CONTAINING 0.1M CITRIC ACID/NAOH PH 3.0,
20% W/V PEG 6,000, AND 20% GLYCEROL AND 20MM UCB-84).
|
Resolution 1.85 Å R-free 0.213 |
| 6C98 Crystal structure of FcRn bound to UCB-84 Deposited 2018-01-25 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
24–297(274 aa)
|
Not recorded | CYS CYSTEINE × 1 ER7 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.0 AND 20% W/V PEG 6,000. CRYSTALS OF FCRN WERE SOAKED FOR
THREE DAYS IN BUFFER CONTAINING 0.1M CITRIC ACID/NAOH PH 3.0,
20% W/V PEG 6,000, AND 20% GLYCEROL AND 20MM UCB-84).
|
Resolution 1.85 Å R-free 0.213 |
| 6C99 Crystal structure of FcRn bound to UCB-303 Deposited 2018-01-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
24–297(274 aa)
|
Not recorded | EQY methyl 7-(3,5-difluorophenyl)-5-(pyridin-3-yl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 GOL GLYCEROL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A
PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.01-3.09 AND 12-16% W/V PEG 6,000. CRYSTALS OF FCRN WERE SOAKED FOR THREE DAYS IN BUFFER CONTAINING 0.1M CITRIC ACID/NAOH PH 3.0, 20% W/V PEG6,000, AND 20% GLYCEROL AND 12.5MM UCB-303.
|
Resolution 2.00 Å R-free 0.220 |
| 6C99 Crystal structure of FcRn bound to UCB-303 Deposited 2018-01-25 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
24–297(274 aa)
|
Not recorded | EQY methyl 7-(3,5-difluorophenyl)-5-(pyridin-3-yl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate × 1 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 3;289 K;APO FCRN CRYSTALS WERE PRODUCED BY SITTING DROP VAPOR DIFFUSION WITH AN EQUAL VOLUME COMBINATION OF THE PROTEIN COMPLEX, PROVIDED IN A
PROTEIN SOLUTION CONTAINING 50MM HEPES PH 7.0 AND 75MM NACL,
AND AN OPTIMIZATION SCREEN CONTAINING 0.1M CITRIC ACID/NAOH PH
3.01-3.09 AND 12-16% W/V PEG 6,000. CRYSTALS OF FCRN WERE SOAKED FOR THREE DAYS IN BUFFER CONTAINING 0.1M CITRIC ACID/NAOH PH 3.0, 20% W/V PEG6,000, AND 20% GLYCEROL AND 12.5MM UCB-303.
|
Resolution 2.00 Å R-free 0.220 |
| 6FGB Human FcRn extra-cellular domain complexed with Fab fragment of Rozanolixizumab Deposited 2018-01-10 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
24–365(342 aa)
|
Not recorded | CL CHLORIDE ION × 2 NA SODIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;291.15 K;0.1M Sodium citrate pH 5.5, 11% PEG6000
|
Resolution 2.90 Å R-free 0.284 |
| 6ILM Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 Deposited 2018-10-19 | Assembly 1 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 540-meric(540) Review required |
Chain E
28–290(263 aa)
|
Not recorded | SPH SPHINGOSINE × 60 K POTASSIUM ION × 60 NA SODIUM ION × 60 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6ILM Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 Deposited 2018-10-19 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: nonameric(9) Review required |
Chain E
28–290(263 aa)
|
Not recorded | SPH SPHINGOSINE × 1 K POTASSIUM ION × 1 NA SODIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6ILM Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 Deposited 2018-10-19 | Assembly 3 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 45-meric(45) Review required |
Chain E
28–290(263 aa)
|
Not recorded | SPH SPHINGOSINE × 5 K POTASSIUM ION × 5 NA SODIUM ION × 5 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6ILM Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 Deposited 2018-10-19 | Assembly 4 Protein heterocomplex Heteromer;Protein × 36 PDB declaration: 54-meric(54) Review required |
Chain E
28–290(263 aa)
|
Not recorded | SPH SPHINGOSINE × 6 K POTASSIUM ION × 6 NA SODIUM ION × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6ILM Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 Deposited 2018-10-19 | Assembly 5 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: nonameric(9) Review required |
Chain E
28–290(263 aa)
|
Not recorded | SPH SPHINGOSINE × 1 K POTASSIUM ION × 1 NA SODIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6LA6 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 7.4 Deposited 2019-11-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.39 Å |
| 6LA6 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 7.4 Deposited 2019-11-12 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.39 Å |
| 6LA6 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 7.4 Deposited 2019-11-12 | Assembly 3 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.39 Å |
| 6LA6 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 7.4 Deposited 2019-11-12 | Assembly 4 Protein heterocomplex Heteromer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.39 Å |
| 6LA6 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 7.4 Deposited 2019-11-12 | Assembly 5 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.39 Å |
| 6LA7 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5 Deposited 2019-11-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 5.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å |
| 6LA7 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5 Deposited 2019-11-12 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 5.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å |
| 6LA7 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5 Deposited 2019-11-12 | Assembly 3 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 5.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å |
| 6LA7 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5 Deposited 2019-11-12 | Assembly 4 Protein heterocomplex Heteromer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 5.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å |
| 6LA7 Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5 Deposited 2019-11-12 | Assembly 5 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 5.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å |
| 6NHA Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody Deposited 2018-12-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
24–296(273 aa)
|
Not recorded | NHE 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 9.5;277.15 K;0.1M CHES pH 9.5
50% polyethylene glycol 200
|
Resolution 2.38 Å R-free 0.245 |
| 6QIO Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the human growth hormone derivative somapacitan Deposited 2019-01-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
24–297(274 aa)
|
Not recorded | MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 CYS CYSTEINE × 2 JG5 Somapacitan × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5;293 K;ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.95 Å R-free 0.226 |
| 6QIP Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan Deposited 2019-01-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
24–297(274 aa)
|
Not recorded | MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 JG5 Somapacitan × 1 BME BETA-MERCAPTOETHANOL × 1 CYS CYSTEINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;293 K;sodium cacodylate, PEG3350
|
Resolution 2.45 Å R-free 0.259 |
| 6WNA Next generation monomeric IgG4 Fc Deposited 2020-04-22 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
27–290(264 aa)
Fragment:extracellular region
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;295 K;0.2 M magnesium chloride hexahydrate, 30% 1,5-diaminopentane dihydrochloride, 0.1 M MES, pH 6 and 20% PEG 6000 at a protein concentration of 6 mg/mL
|
Resolution 2.40 Å R-free 0.263 |
| 6WOL Next generation monomeric IgG4 Fc bound to neonatal Fc receptor Deposited 2020-04-24 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
24–290(267 aa)
Fragment:extracellular domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 6;295 K;0.2 M magnesium chloride hexahydrate, 1 M sodium iodide, 0.1 M MES, pH 6 and 20% PEG 6000 at a protein concentration of 6.35 mg/mL
|
Resolution 2.49 Å R-free 0.270 |
| 7B5F Structure of echovirus 18 in complex with neonatal Fc receptor Deposited 2020-12-03 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: Hexameric(6) Consistent with protein count |
Chain G
24–290(267 aa)
|
Not recorded | PLM PALMITIC ACID × 1 GUN GUANINE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.3;Mixed in 1:1 volume ratio
{20 mM Tris (pH=7.2), 100 mM NaCl} and {8 mM Na2HPO4, 2 mM KH2PO4 (pH=7.4), 137 mM NaCl, 2.7 mM KCl}=PBS
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å R-free 0.311 |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 60 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 3 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 5 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 4 Protein heterocomplex Heteromer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 5 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7C9V E30 F-particle in complex with FcRn Deposited 2020-06-07 | Assembly 6 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | MYR MYRISTIC ACID × 60 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 7Q15 Crystal structure of FcRn and beta-2-microglobulin in complex with IgG1-Fc-MST-HN (efgartigimod) Deposited 2021-10-18 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
1–297(297 aa)
Chain C
1–297(297 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;294 K;0.1 M Sodium Cacodylate pH 7
|
Resolution 3.30 Å R-free 0.231 |
| 7XXA Complex of Echo 18 and FcRn at pH7.4 Deposited 2022-05-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 300 PDB declaration: 300-meric(300) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 3 seconds and wait for 3 seconds before plunging
|
Resolution 3.09 Å |
| 7XXA Complex of Echo 18 and FcRn at pH7.4 Deposited 2022-05-29 | Assembly 2 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 3 seconds and wait for 3 seconds before plunging
|
Resolution 3.09 Å |
| 7XXA Complex of Echo 18 and FcRn at pH7.4 Deposited 2022-05-29 | Assembly 3 Protein heterocomplex Heteromer;Protein × 25 PDB declaration: 25-meric(25) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 3 seconds and wait for 3 seconds before plunging
|
Resolution 3.09 Å |
| 7XXA Complex of Echo 18 and FcRn at pH7.4 Deposited 2022-05-29 | Assembly 4 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 3 seconds and wait for 3 seconds before plunging
|
Resolution 3.09 Å |
| 7XXA Complex of Echo 18 and FcRn at pH7.4 Deposited 2022-05-29 | Assembly 5 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain E
28–290(263 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE;blot for 3 seconds and wait for 3 seconds before plunging
|
Resolution 3.09 Å |
| 9DBT Crystal structure of human astrovirus 1 capsid spike bound to human neonatal Fc receptor Deposited 2024-08-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain C
24–297(274 aa)
Chain F
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.1;295.15 K;Sodium chloride, Ammonium sulfate, BIS-TRIS
|
Resolution 3.40 Å R-free 0.263 |
| 9DBT Crystal structure of human astrovirus 1 capsid spike bound to human neonatal Fc receptor Deposited 2024-08-23 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
24–297(274 aa)
Chain I
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.1;295.15 K;Sodium chloride, Ammonium sulfate, BIS-TRIS
|
Resolution 3.40 Å R-free 0.263 |
| 9MI6 Crystal structure of human FcRn in complex with nipocalimab Fab fragment Deposited 2024-12-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
24–297(274 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;277.15 K;10% PEG 1000, 10% PEG 8000
|
Resolution 2.41 Å R-free 0.248 |
| 9NAV CryoEM structure of human astrovirus 1 spike in complex with human neonatal Fc receptor Deposited 2025-02-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count |
Chain G
24–290(267 aa)
Chain I
24–290(267 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.81 Å |
| 9OC6 Crystal structure of receptor FcRn bound to Human Astrovirus 6 spike Deposited 2025-04-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain C
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.1M HEPES, 30% 1,2-propanediol, 20% PEG-400
|
Resolution 2.97 Å R-free 0.281 |
| 9OC7 Crystal structure of FcRn in complex with Human Astrovirus 2 spike Deposited 2025-04-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain E
24–297(274 aa)
Chain Y
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.9;293 K;25% 1,2-propanediol, 10% glycerol, 5% PEG-3000, 0.1 M phosphate-citrate
|
Resolution 3.07 Å R-free 0.239 |
| 9WYD Crystal structure of HAstV8 spike and FcRn Deposited 2025-09-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
24–297(274 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
LIQUID DIFFUSION;291.15 K;0.1 M BICINE pH 8.5, 8% w/v Polyethylene glycol monomethyl ether 5,000
|
Resolution 2.65 Å R-free 0.232 |