← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q8TCS8 New Search
11PDB entries
12Biological assembly
33chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3U1K Crystal structure of human PNPase Deposited 2011-09-30 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–669（624 aa） Fragment：UNP residues 46-669
Not recorded CIT CITRIC ACID × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；298 K；10%(v/v) 2-Propanol, 0.1M Sodium citrate tribasic dihydrate, 26%(v/v) Polyethylene glycol 400 , pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.13 Å R-free 0.223
3U1K Crystal structure of human PNPase Deposited 2011-09-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 46–669（624 aa） Fragment：UNP residues 46-669
Chain C 46–669（624 aa） Fragment：UNP residues 46-669
Chain D 46–669（624 aa） Fragment：UNP residues 46-669
Not recorded CIT CITRIC ACID × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；298 K；10%(v/v) 2-Propanol, 0.1M Sodium citrate tribasic dihydrate, 26%(v/v) Polyethylene glycol 400 , pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.13 Å R-free 0.223
5ZF6 Crystal structure of the dimeric human PNPase Deposited 2018-03-02 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 46–669（624 aa）
Chain B 46–669（624 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298.15 K；0.1M citrate buffer (pH 5.0), 10% (v/v) 2-propanol, 26% (v/v) polyethylene glycol 400
Resolution 2.80 Å R-free 0.249
9KJR The cryo-EM structure of human PNPase in the open conformation Deposited 2024-11-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–753（708 aa）
Chain B 46–753（708 aa）
Chain C 46–753（708 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
9KJT The cryo-EM structure of human PNPase in the closed conformation Deposited 2024-11-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.84 Å
9NJB hPNPase RNA pre-catalytic state Deposited 2025-02-27 Assembly 1 Protein–RNA Homooligomer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded SO4 SULFATE ION × 3 MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.15 Å
9NJC hPNPase bound to PO4 in loop conformation 1 Deposited 2025-02-27 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded PO4 PHOSPHATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.36 Å
9NJD hPNPase bound to PO4 in loop conformation 3 Deposited 2025-02-27 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded PO4 PHOSPHATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.44 Å
9NJE hPNPase bound to PO4 in loop conformation 2 Deposited 2025-02-27 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded PO4 PHOSPHATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.44 Å
9NO0 hPNPase RNA loading state Deposited 2025-03-07 Assembly 1 Protein–RNA Homooligomer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded PO4 PHOSPHATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.08 Å
9XYI hPNPase RNA loading state Deposited 2025-08-26 Assembly 1 Protein–RNA Homooligomer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded SO4 SULFATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.46 Å
9XZF hPNPase RNA loading state with extended RNA in the bottom Deposited 2025-08-27 Assembly 1 Protein–RNA Homooligomer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 46–783（738 aa）
Chain B 46–783（738 aa）
Chain C 46–783（738 aa）
Not recorded PO4 PHOSPHATE ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.65 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.