Current Protein Identity：Q99759
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2C60 crystal structure of human mitogen-activated protein kinase kinase kinase 3 isoform 2 phox domain at 1.25 A resolution Deposited 2005-11-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
37–124（88 aa）
Fragment：PHOX DOMAIN, RESIDUES 37-124
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；150 NANOLITRE SITTING DROPS, 0.2 KSCN, 20% PEG3350, 10% ETHYLENE GLYCOL
|
Resolution 1.25 Å R-free 0.182 |
| 2JRH Solution structure of human MEKK3 PB1 domain cis isomer Deposited 2007-06-26 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
42–126（85 aa）
Fragment：OPR, PB1 domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6；298 K；Pressure 1
NMR sample composition
0.5 mM [U-100% 13C; U-100% 15N] MEKK3 PB1-cis, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.8 mM [U-100% 15N] MEKK3 PB1-cis, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2O2V Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox) Deposited 2006-11-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
37–124（88 aa）
Fragment：MAP3K3B-phox
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；277 K；0.02M CaCl2, 0.1M Na(CH3COO), 30% MPD, pH 4.6, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
Resolution 1.83 Å R-free 0.224 |
| 2PPH solution structure of human MEKK3 PB1 domain Deposited 2007-04-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
42–126（85 aa）
Fragment：PB1 domain (Residues 42-126)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6；298 K；Pressure 1
NMR sample composition
0.5mM 15N,13C-labeled MEKK3 PB1
50mM phosphate buffer (pH 6.0), 1mM EDTA,10%(v/v) D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 4Y5O CCM2 HHD in complex with MEKK3 NPB1 Deposited 2015-02-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–124（124 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M potassium phosphate and 20% PEG 3350
|
Resolution 2.35 Å R-free 0.232 |
| 4YL6 Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3 Deposited 2015-03-05 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–22（22 aa）
Fragment：UNP residues 1-22
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；3.5 M Sodium Formate
|
Resolution 2.10 Å R-free 0.237 |