Current Protein Identity：Q9NPD3
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2NN6 Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 Deposited 2006-10-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count |
Chain B
1–244（244 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；291 K；4.5-8% w/v PEG4000, 0.1M Sodium citrate, 1 mM TCEP, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.35 Å R-free 0.344 |
| 6D6Q Human nuclear exosome-MTR4 RNA complex - overall reconstruction Deposited 2018-04-22 | Assembly 1 Other combination Heteromer；Protein × 13 PDB declaration: pentadecameric（15） Consistent with all polymers |
Chain B
1–245（245 aa）
|
Not recorded | MG MAGNESIUM ION × 1 ZN ZINC ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；30 sec wait time, 2.5 sec blot time
|
Resolution 3.45 Å |
| 6D6R Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction Deposited 2018-04-22 | Assembly 1 Other combination Heteromer；Protein × 13 PDB declaration: pentadecameric（15） Consistent with all polymers |
Chain B
1–245（245 aa）
|
Not recorded | ZN ZINC ION × 1 MG MAGNESIUM ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；30 sec wait time, 2.5 sec blot time
|
Resolution 3.45 Å |
| 6H25 Human nuclear RNA exosome EXO-10-MPP6 complex Deposited 2018-07-13 | Assembly 1 Protein–RNA Heteromer；Protein × 11 PDB declaration: dodecameric（12） Consistent with all polymers |
Chain B
1–245（245 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.80 Å |
| 9G8M human 80S ribosome bound by a SKI2-exosome complex Deposited 2024-07-23 | Assembly 1 Insufficient information Heteromer；Protein × 87 PDB declaration: 92-meric（92） Consistent with all polymers |
Chain L
1–245（245 aa）
|
Not recorded | MG MAGNESIUM ION × 232 ZN ZINC ION × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.30 Å |
| 9G8N 80S-bound human Ski2-exosome complex Deposited 2024-07-23 | Assembly 1 Protein–RNA Heteromer；Protein × 12 PDB declaration: 13-meric（13） Consistent with all polymers |
Chain L
1–245（245 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.70 Å |
| 9G8O human 40S ribosome bound by a SKI238-exosome complex Deposited 2024-07-23 | Assembly 1 Protein–RNA Heteromer；Protein × 49 PDB declaration: 51-meric（51） Consistent with all polymers |
Chain N
1–245（245 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.40 Å |
| 9G8P 40S-bound human SKI2-exosome complex Deposited 2024-07-23 | Assembly 1 Protein–RNA Heteromer；Protein × 12 PDB declaration: 13-meric（13） Consistent with all polymers |
Chain L
1–245（245 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 7.00 Å |