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11hl

;SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement) ;

Method: ELECTRON MICROSCOPY Dmax: 117.1 Å Quality: GOOD

SAXS Profile

SAXS profile for 11hl

P(r) Distribution

P(r) distribution for 11hl
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1. Structure Basics

entry_id11hl
deposition_date2026-02-24
title;SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement) ;
keywords;S2prime, coronavirus, SARS-CoV-2, spike, fusion, entry, antiviral, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN-HYDROLASE complex, VN01H1, VIRAL PROTEIN ;; VIRAL PROTEIN
methodELECTRON MICROSCOPY
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Download Data

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2. SAXS Parameters (CRYSOL)

rg_guinier33.58 Å
rg_electron34.02 Å
i082734700.00
molecular_weight72193.0 kDa
excluded_volume90304 ų
envelope_volume117750 ų
shell_volume31225 ų
envelope_diameter124.8 Å
shell_rg37.47 Å
envelope_rg34.11 Å
shape_rg34.02 Å
total_rg34.29 Å
total_atoms5088
n_residues675
n_harmonics20
q_range— – 0.5000 Å−1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3
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3. P(r) Analysis (GNOM)

dmax117.1 Å
rg_real33.93 Å
rg_real_error1.31 Å
i0_real8.2730e+07
i0_real_error1.4570e+06
rg_reciprocal33.71 Å
i0_reciprocal82720000.0000
total_estimate0.7605
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary29.9 Å
skewness0.611
kurtosis-0.186
angular_range— – 0.2350 Å−1
current_alpha0.0000
highest_alpha14310000.0000
n_real_points48
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.658; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.551; Smooth: 0.358
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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

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6. Citations (1)

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7. Files & Curves (10)