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1a8i

SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

GLYCOGEN PHOSPHORYLASE B

OrganismNot specified

UniProt P00489

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1b4d 1kti 1xkx 1xl0 1xl1 2amv 2fet 2ff5 2pyd 2pyi 3cut 3cuu

26 assemblies; showing the first 12

Homodimer
1a8i 1axr 1bx3 1c50 1c8k 1c8l 1e1y 1fs4 1ftq 1ftw 1fty 1fu4

222 assemblies; showing the first 12

Homotetramer
1abb 1gpa 1noi 1pyg 3e3n 3e3n 7gpb 9gpb

8 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1p29 1p2b 1p2d 1p2g 5gpb 6gpb

6 assemblies

View Construct and Data Evidence
UniProt name PHS2_RABIT
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–842； UniProt 1–842

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1a8i
Deposition date deposition_date1998-03-25
Structure title titleSPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE
Keywords keywordsGLYCOGEN PHOSPHORYLASE, GLUCOPYRANOSE SPIROHYDANTOIN, WATER STRUCTURE, INHIBITOR BINDING, ANTI-HYPERGLYCEMIC AGENT; GLYCOGEN PHOSPHORYLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1a8i__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1a8i__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1a8i__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）38.95 Å
Rg (electron density)38.41 Å
Total Rg38.85 Å
Atom count13318
Residues1624
Excluded volume236880 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1a8i__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1a8ia_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.87 — UDP-Glycosyltransferase/glycogen phosphorylase
Superfamily Superfamily superfamilyc.87.1 — UDP-Glycosyltransferase/glycogen phosphorylase
Family Family familyc.87.1.4 — Oligosaccharide phosphorylase

CATH v4.4 (2 domains)

Domain ID domain_id1a8iA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily2000 — Glycogen Phosphorylase B;
Domain ID domain_id1a8iA02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily2000 — Glycogen Phosphorylase B;
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7. Citations (6)