1c8l
SYNERGISTIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG AND CAFFEINE
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1c8l |
| deposition_date | 2000-05-16 |
| title | SYNERGISTIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG AND CAFFEINE |
| keywords | GLYCOGEN METABOLISM, DIABETES, PHOSPHORYLASE A, SYNERGISTIC INHIBITION, ALLOSTERIC SITE, INHIBITOR SITE, TRANSFERASE; TRANSFERASE |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 28.56 Å |
| rg_electron | 27.48 Å |
| i0 | 141848000.00 |
| molecular_weight | 94685.0 kDa |
| excluded_volume | 118660 ų |
| envelope_volume | 139810 ų |
| shell_volume | 40658 ų |
| envelope_diameter | 98.8 Å |
| shell_rg | 36.35 Å |
| envelope_rg | 27.98 Å |
| shape_rg | 27.47 Å |
| total_rg | 28.30 Å |
| total_atoms | 6674 |
| n_residues | 811 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 95.7 Å |
| rg_real | 28.41 Å |
| rg_real_error | 0.64 Å |
| i0_real | 1.4180e+08 |
| i0_real_error | 2.2690e+06 |
| rg_reciprocal | 28.46 Å |
| i0_reciprocal | 141900000.0000 |
| total_estimate | 0.8789 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 34.2 Å |
| skewness | 0.237 |
| kurtosis | -0.384 |
| angular_range | — – 0.2800 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 40750000.0000 |
| n_real_points | 57 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.810; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.990 |