Glycogen phosphorylase, muscle form
OrganismNot specified
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Other combination Homooligomer Protein × 2 其他Polymer 2 PDB declaration: dimeric（2） Consistent with protein copy count | Chain A； UniProt 1–842 | Not recorded | ;alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose ; × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION X-ray crystallization conditions：SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K | Resolution 2.20 Å R-free 0.217 |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 1P2B | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1A8I SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE Deposited 1998-03-25 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLS BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；THE PROTEIN WAS CRYSTALLIZED FROM 0.01 M BES, PH 6.7, 0.003 M DTT, 0.001 M SPERMINE, 0.0001 M SODIUM EDTA, 0.02 % SODIUM AZIDE AT 16 DEGREES C. THE CRYSTALS WERE SOAKED IN 0.1 M SPIROHYDANTOIN AND CRYOPROTECTED WITH 25% (V/V) MPD (2-METHYL-2,4- PENTANEDIOL)., temperature 289K
|
Resolution 1.78 Å R-free 0.229 |
| 1ABB CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE Deposited 1992-04-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
10–837（828 aa）
Chain B
10–837（828 aa）
Chain C
10–837（828 aa）
Chain D
10–837（828 aa）
|
Not recorded | SO4 SULFATE ION × 4 PDP PYRIDOXAL-5'-DIPHOSPHATE × 4 IMP INOSINIC ACID × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.80 Å |
| 1AXR COOPERATIVITY BETWEEN HYDROGEN-BONDING AND CHARGE-DIPOLE INTERACTIONS IN THE INHIBITION OF BETA-GLYCOSIDASES BY AZOLOPYRIDINES: EVIDENCE FROM A STUDY WITH GLYCOGEN PHOSPHORYLASE B Deposited 1997-10-20 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PO4 PHOSPHATE ION × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 HTP 4,5,6-TRIHYDROXY-7-HYDROXYMETHYL-4,5,6,7-TETRAHYDRO-1H-[1,2,3]TRIAZOLO[1,5-A]PYRIDIN-8-YLIUM × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
soak native crystals；pH 6.7；NATIVE T-STATE GLYCOGEN PHOSPHORYLASE CRYSTALS WERE SOAKED WITH 10 MM BES, 0.1 MM EDTA AND 0.02% SODIUM AZIDE SOLUTION CONTAINING 5 MM TRIAZOLE AND 50 MM SODIUM DIHYDROGEN PHOSPHATE FOR 1 HOUR., pH 6.7, soak native crystals
|
Resolution 2.30 Å R-free 0.276 |
| 1B4D AMIDOCARBAMATE INHIBITOR OF GLYCOGEN PHOSPHORYLASE Deposited 1998-12-18 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | CRA 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 IMP INOSINIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；CO-CRYSTALLIZED COMPLEX WAS OBTAINED FROM 0.01 M BES, PH 6.7, 0.003 M DTT, 0.001 M SPERMINE, 0.0001 M SODIUM EDTA, 0.02 % SODIUM AZIDE AND 0.01 M AMIDOCARBAMATE AT 16 DEGREES C. JUST BEFORE DATA COLLECTION, THE CRYSTALS WERE TRANSFERRED TO A FRESH SOLUTION OF THE ABOVE BUFFER CONTAINING 30% GLYCEROL FOR 30-60 SEC., temperature 289K
|
Resolution 2.00 Å R-free 0.229 |
| 1BX3 EFFECTS OF COMMONLY USED CRYOPROTECTANTS ON GLYCOGEN PHOSPHORYLASE ACTIVITY AND STRUCTURE Deposited 1999-10-13 | Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；THE PROTEIN WAS CRYSTALLIZED FROM 0.01 M BES, PH 6.7, 0.003 M DTT, 0.001 M SPERMINE, 0.0001 M EDTA, 0.02 % (W/V) SODIUM AZIDE AT 16 DEGREES C. THE CRYSTALS WERE CRYOPROTECTED WITH 30% (V/V) DMSO (DIMETHYLSULFOXIDE)., temperature 289K
|
Resolution 2.30 Å R-free 0.252 |
| 1C50 IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF A NOVEL ALLOSTERIC BINDING SITE OF GLYCOGEN PHOSPHORYLASE B Deposited 1999-12-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–842（830 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CHI 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；PHOSPHORYLASE B-CP320626 COMPLEX WAS CO-CRYSTALLISED UNDER CONDITIONS SIMILAR
TO THOSE DESCRIBED BY ZOGRAPHOS ET AL., (1997) STRUCTURE 5, 1413-1425., pH 6.7
|
Resolution 2.30 Å R-free 0.246 |
| 1C8K FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE Deposited 2000-05-11 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CPB 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；pH 6.70
|
Resolution 1.76 Å R-free 0.244 |
| 1C8L SYNERGISTIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG AND CAFFEINE Deposited 2000-05-16 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BIN 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM × 2 CFF CAFFEINE × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；pH 6.70
|
Resolution 2.30 Å R-free 0.257 |
| 1E1Y Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site Deposited 2000-05-11 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | CPB 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE × 2 PO3 PHOSPHITE ION × 2 GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；AS DESCRIBED PREVIOUSLY BY OIKONOMAKOS ET AL. (1999) PROTEIN SCIENCE 8, 1930-1945., pH 6.70
|
Resolution 2.23 Å R-free 0.252 |
| 1FS4 Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design Deposited 2000-09-08 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CRA 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, IMP, spermine, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.38 Å R-free 0.227 |
| 1FTQ STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GL2 (5S,7R,8S,9S,10R)-3-amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；10 mM BES, 0.1 MM EDTA, 1 mM IMP, 1 mM spermine, pH 6.70, SMALL TUBES, temperature 298K
|
Resolution 2.35 Å R-free 0.228 |
| 1FTW STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GL5 (5S,7R,8S,9S,10R)-3,8,9,10-tetrahydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES, 0.1 MM EDTA, 1 mM IMP, 1 mM spermine , pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.36 Å R-free 0.214 |
| 1FTY STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GL7 8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-3-METHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES, 0.1 MM EDTA, 1 mM IMP, 1 mM spermine , pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.38 Å R-free 0.243 |
| 1FU4 STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-14 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GL9 N-[(5S,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2,4-dioxo-6-oxa-1,3-diazaspiro[4.5]dec-3-yl]acetamide × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES, 0.1 mM EDTA, 1 mM IMP, 1 mM spermine, pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.36 Å R-free 0.224 |
| 1FU7 STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-14 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CR1 N-(methoxycarbonyl)-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES, 0.1 MM EDTA, 1 mM IMP, 1 mM spermine , pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.36 Å R-free 0.209 |
| 1FU8 STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN Deposited 2000-09-14 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CR6 1-DEOXY-1-ACETYLAMINO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES, 0.1 MM EDTA, 1 mM IMP, 1 mM spermine, pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.35 Å R-free 0.240 |
| 1GFZ FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE Deposited 2000-06-29 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 CFF CAFFEINE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；A single native T-state GPb crystal was soaked in a solution containing 5 mM caffeine,
10 mM Bes, 0.1 mM EDTA buffer, pH 6.7 for 80 min, pH 6.70, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.30 Å R-free 0.219 |
| 1GG8 DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS Deposited 2000-07-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GLG ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；T-STATE GPB CRYSTALS (OIKONOMAKOS ET AL., 1985, BBA 832, 248) WERE SOAKED FOR 1 H IN A BUFFERED SOLUTION [10 MM BES, 0.1 MM EDTA, PH 6.7] CONTAINING A 100 MM CONCENTRATION OF THE COMPOUND. , pH 6.70
|
Resolution 2.31 Å R-free 0.253 |
| 1GGN Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design Deposited 2000-08-29 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GLS BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；T-STATE GPB CRYSTALS
(OIKONOMAKOS ET AL., 1985, BBA 832, 248) WERE SOAKED FOR
1 H IN A BUFFERED SOLUTION [10 MM BES, 0.1 MM EDTA, PH
6.7] CONTAINING A 100 MM CONCENTRATION OF THE COMPOUND. , pH 6.70
|
Resolution 2.36 Å R-free 0.233 |
| 1GPA STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP Deposited 1990-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 8 PLP PYRIDOXAL-5'-PHOSPHATE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.90 Å |
| 1GPA STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP Deposited 1990-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.90 Å |
| 1GPA STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP Deposited 1990-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.90 Å |
| 1GPB GLYCOGEN PHOSPHORYLASE B: DESCRIPTION OF THE PROTEIN STRUCTURE Deposited 1990-06-04 | Different oligomeric state Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.90 Å |
| 1GPY CRYSTALLOGRAPHIC BINDING STUDIES ON THE ALLOSTERIC INHIBITOR GLUCOSE-6-PHOSPHATE TO T STATE GLYCOGEN PHOSPHORYLASE B Deposited 1993-03-31 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | G6P 6-O-phosphono-alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.40 Å |
| 1H5U THE 1.76 A RESOLUTION CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE B COMPLEXED WITH GLUCOSE AND CP320626, A POTENTIAL ANTIDIABETIC DRUG Deposited 2001-05-25 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CHI 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE × 2 GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；PHOSPHORYLASE B-GLC-CP320626 COMPLEX WAS CO-CRYSTALLISED UNDER CONDITIONS SIMILAR TO THOSE DESCRIBED BY OIKONOMAKOS ET AL., (2000) STRUCTURE 8, 575-584., pH 6.70
|
Resolution 1.76 Å R-free 0.235 |
| 1HLF BINDING OF GLUCOPYRANOSYLIDENE-SPIRO-THIOHYDANTOIN TO GLYCOGEN PHOSPHORYLASE B: KINETIC AND CRYSTALLOGRAPHIC STUD Deposited 2000-12-01 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 GL4 (5S,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2-thioxo-6-oxa-1,3-diazaspiro[4.5]decan-4-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；CRYSTALLIZATION CONDITIONS: T-STATE GPB CRYSTALS
(OIKONOMAKOS ET AL., 1985, BBA 832, 248) WERE SOAKED FOR
1 H IN A BUFFERED SOLUTION [10 MM BES, 0.1 MM EDTA, PH
6.7] CONTAINING A 70 MM CONCENTRATION OF THE COMPOUND, pH 6.70, SMALL TUBES, temperature 289K
|
Resolution 2.26 Å R-free 0.221 |
| 1K06 Crystallographic Binding Study of 100 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase b Deposited 2001-09-18 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | BZD N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, 100mM N-benzoyl-N'-beta-D-glucopyranosyl urea, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 1.80 Å R-free 0.246 |
| 1K08 Crystallographic Binding Study of 10 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase b Deposited 2001-09-18 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | BZD N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, 10mM N-benzoyl-N'-beta-D-glucopyranosyl urea, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 2.26 Å R-free 0.212 |
| 1KTI BINDING OF 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA TO GLYCOGEN PHOSPHORYLASE B: KINETIC AND CRYSTALLOGRAPHIC STUDIES Deposited 2002-01-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | AZC N-(acetylcarbamoyl)-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.97 Å R-free 0.219 |
| 1KTI BINDING OF 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA TO GLYCOGEN PHOSPHORYLASE B: KINETIC AND CRYSTALLOGRAPHIC STUDIES Deposited 2002-01-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | AZC N-(acetylcarbamoyl)-beta-D-glucopyranosylamine × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.97 Å R-free 0.219 |
| 1KTI BINDING OF 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA TO GLYCOGEN PHOSPHORYLASE B: KINETIC AND CRYSTALLOGRAPHIC STUDIES Deposited 2002-01-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | AZC N-(acetylcarbamoyl)-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, 100 MM N-ACETYL-N'-BETA-D-GLUCOPYRANOSYL UREA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.97 Å R-free 0.219 |
| 1LWN Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution Deposited 2002-06-01 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；295 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 295K
|
Resolution 2.00 Å R-free 0.218 |
| 1LWO Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution Deposited 2002-06-01 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 CHI 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 298K
|
Resolution 2.00 Å R-free 0.235 |
| 1NOI COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES Deposited 1996-03-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
|
Not recorded | PO4 PHOSPHATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 NTZ NOJIRIMYCINE TETRAZOLE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.50 Å R-free 0.273 |
| 1NOI COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES Deposited 1996-03-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Not recorded | PO4 PHOSPHATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 NTZ NOJIRIMYCINE TETRAZOLE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.50 Å R-free 0.273 |
| 1NOI COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES Deposited 1996-03-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Not recorded | PO4 PHOSPHATE ION × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 4 NTZ NOJIRIMYCINE TETRAZOLE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.50 Å R-free 0.273 |
| 1NOJ COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE Deposited 1996-03-12 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PO4 PHOSPHATE ION × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 NTZ NOJIRIMYCINE TETRAZOLE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.40 Å |
| 1NOK COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE Deposited 1996-03-12 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 NTZ NOJIRIMYCINE TETRAZOLE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.40 Å |
| 1P29 Crystal Structure of glycogen phosphorylase b in complex with maltopentaose Deposited 2003-04-15 | Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；295 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 295K
|
Resolution 2.20 Å R-free 0.215 |
| 1P2D Crystal Structure of Glycogen Phosphorylase B in complex with Beta Cyclodextrin Deposited 2003-04-15 | Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.94 Å R-free 0.218 |
| 1P2G Crystal Structure of Glycogen Phosphorylase B in complex with Gamma Cyclodextrin Deposited 2003-04-15 | Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.30 Å R-free 0.232 |
| 1P4G Crystal structure of glycogen phosphorylase b in complex with C-(1-azido-alpha-D-glucopyranosyl)formamide Deposited 2003-04-23 | Different oligomeric state Different ligand/ion Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CGF C-(1-AZIDO-ALPHA-D-GLUCOPYRANOSYL) FORMAMIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.10 Å R-free 0.204 |
| 1P4H Crystal structure of glycogen phosphorylase b in complex with C-(1-acetamido-alpha-D-glucopyranosyl) formamide Deposited 2003-04-23 | Different oligomeric state Different ligand/ion Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | CR6 1-DEOXY-1-ACETYLAMINO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE × 2 PO4 PHOSPHATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.06 Å R-free 0.205 |
| 1P4J Crystal structure of glycogen phosphorylase b in complex with C-(1-hydroxy-beta-D-glucopyranosyl)formamide Deposited 2003-04-23 | Different oligomeric state Different ligand/ion Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CBF (2R,3R,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)oxane-2-carboxamide × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.198 |
| 1PYG STRUCTURAL BASIS FOR THE ACTIVATION OF GLYCOGEN PHOSPHORYLASE B BY ADENOSINE MONOPHOSPHATE Deposited 1992-07-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Not recorded | AMP ADENOSINE MONOPHOSPHATE × 4 PDP PYRIDOXAL-5'-DIPHOSPHATE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.87 Å |
| 1UZU Glycogen Phosphorylase b in complex with indirubin-5'-sulphonate Deposited 2004-03-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 INR 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, PH 6.7, SMALL TUBES, TEMPERATURE 289K
|
Resolution 2.30 Å R-free 0.214 |
| 1WUT Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes Deposited 2004-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | BN2 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；10mM Bes buffer, 3mM DDT, pH 6.7, SMALL TUBES, temperature 298K
|
Resolution 2.26 Å R-free 0.236 |
| 1WUY Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site Deposited 2004-12-09 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BN3 4-[3-CHLORO-4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]BUTANOIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；10mM Bes buffer, 3mM DDT, pH 6.7, SMALL TUBES, temperature 298K
|
Resolution 2.26 Å R-free 0.232 |
| 1WV0 Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site Deposited 2004-12-10 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BN4 4-[4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2,3-DIMETHYLPHENOXY]BUTANOIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；10mM BES, 3mM DTT, pH 6.7, SMALL TUBES, temperature 298K
|
Resolution 2.26 Å R-free 0.240 |
| 1WV1 Crystallographic studies on acyl ureas, a new class of inhibitors of glycogenphosphorylase. Broad specificity of the allosteric site Deposited 2004-12-10 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BN5 5-[3-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2-METHYLPHENOXY]PENTANOIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；298 K；10mM Bes buffer, 3mM DDT, pH 6.7, SMALL TUBES, temperature 298K
|
Resolution 2.26 Å R-free 0.230 |
| 1WW2 Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase Deposited 2004-12-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | NBG N-acetyl-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.90 Å R-free 0.213 |
| 1WW3 Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase Deposited 2004-12-31 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | NTF N-(trifluoroacetyl)-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.80 Å R-free 0.216 |
| 1XC7 Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: Kinetic and crystallographic studies Deposited 2004-09-01 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GL6 N-(dimethoxyphosphoryl)-beta-D-glucopyranosylamine × 2 SO4 SULFATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；298 K；pH 6.8, SMALL TUBES, temperature 298K
|
Resolution 1.83 Å R-free 0.209 |
| 1XKX Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Deposited 2004-09-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | IMK 2-(BETA-D-GLUCOPYRANOSYL)-5-METHYL-1-BENZIMIDAZOLE × 3 PLP PYRIDOXAL-5'-PHOSPHATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；298 K；pH 6.8, SMALL TUBES, temperature 298K
|
Resolution 1.93 Å R-free 0.198 |
| 1XL0 Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Deposited 2004-09-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | OX2 (1R)-1,5-anhydro-1-(5-methyl-1,3,4-oxadiazol-2-yl)-D-glucitol × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 1.92 Å R-free 0.200 |
| 1XL0 Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Deposited 2004-09-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | OX2 (1R)-1,5-anhydro-1-(5-methyl-1,3,4-oxadiazol-2-yl)-D-glucitol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 1.92 Å R-free 0.200 |
| 1XL1 Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Deposited 2004-09-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | TH1 (1R)-1,5-anhydro-1-(5-methyl-1,3-benzothiazol-2-yl)-D-glucitol × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；298 K；pH 6.8, SMALL TUBES, temperature 298K
|
Resolution 2.10 Å R-free 0.203 |
| 1XL1 Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Deposited 2004-09-30 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | TH1 (1R)-1,5-anhydro-1-(5-methyl-1,3-benzothiazol-2-yl)-D-glucitol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；298 K；pH 6.8, SMALL TUBES, temperature 298K
|
Resolution 2.10 Å R-free 0.203 |
| 1Z62 Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites Deposited 2005-03-21 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IAA ({[(3E)-2'-OXO-2',7'-DIHYDRO-2,3'-BIINDOL-3(7H)-YLIDENE]AMINO}OXY)ACETIC ACID × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；291 K；10mM Bes buffer, 3mM DDT , pH 6.7, SMALL TUBES, temperature 291K
|
Resolution 1.90 Å R-free 0.206 |
| 1Z6P Glycogen phosphorylase AMP site inhibitor complex Deposited 2005-03-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Fragment：Glycogen Phosphorylase
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 194 4-{2-[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；293 K；BES, EDTA. DTT, SPERMINE, pH 6.7, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.260 |
| 1Z6Q Glycogen phosphorylase with inhibitor in the AMP site Deposited 2005-03-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Fragment：Glycogen Phosphorylase
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 195 4-{2,4-BIS[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；293 K；BES, EDTA, DTT, SPERMDINE, pH 6.7, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.03 Å R-free 0.270 |
| 2AMV THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID Deposited 1998-10-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BIN 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；PHOSPHORYLASE B WAS COCRYSTALLISED WITH 1 MM W1807 IN A MEDIUM CONSISTING OF 27-28 MG/ML ENZYME, 1 MM SPERMINE, 3 MM DTT, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEG C)., temperature 289K
|
Resolution 2.30 Å R-free 0.282 |
| 2AMV THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID Deposited 1998-10-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 BIN 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；PHOSPHORYLASE B WAS COCRYSTALLISED WITH 1 MM W1807 IN A MEDIUM CONSISTING OF 27-28 MG/ML ENZYME, 1 MM SPERMINE, 3 MM DTT, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEG C)., temperature 289K
|
Resolution 2.30 Å R-free 0.282 |
| 2AMV THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID Deposited 1998-10-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 BIN 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；PHOSPHORYLASE B WAS COCRYSTALLISED WITH 1 MM W1807 IN A MEDIUM CONSISTING OF 27-28 MG/ML ENZYME, 1 MM SPERMINE, 3 MM DTT, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEG C)., temperature 289K
|
Resolution 2.30 Å R-free 0.282 |
| 2F3P Crystal Structure of the glycogen phosphorylase B / N-(beta-D-glucopyranosyl)oxamic acid complex Deposited 2005-11-22 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 4GP N-(carboxycarbonyl)-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.94 Å R-free 0.216 |
| 2F3Q Crystal structure of the glycogen phosphorylase B / methyl-N-(beta-D-glucopyranosyl)oxamate complex Deposited 2005-11-22 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 6GP N-[methoxy(oxo)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.96 Å R-free 0.199 |
| 2F3S Crystal Structure of the glycogen phosphorylase B / ethyl-N-(beta-D-glucopyranosyl)oxamate complex Deposited 2005-11-22 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 7GP N-[ethoxy(oxo)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.96 Å R-free 0.213 |
| 2F3U Crystal Structure of the glycogen phosphorylase B / N-(beta-D-glucopyranosyl)-N'-cyclopropyl oxalamide complex Deposited 2005-11-22 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 8GP N-[(cyclopropylamino)(oxo)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.93 Å R-free 0.210 |
| 2FET Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.213 |
| 2FET Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.213 |
| 2FET Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-16 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.213 |
| 2FF5 Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-19 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.212 |
| 2FF5 Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-19 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.212 |
| 2FF5 Synthesis of C-D-Glycopyranosyl-Hydroquinones and-Benzoquinones. Inhibition of PTP1B. Inhibition of and binding to glycogen phosphorylase in the crystal Deposited 2005-12-19 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 H53 (1S)-1,5-anhydro-1-(2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.212 |
| 2FFR Crystallographic studies on N-azido-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine Deposited 2005-12-20 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
12–836（825 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 DL6 N-(azidoacetyl)-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 0.1 mM EDTA, 0.02% NaN3, 3 mM DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.199 |
| 2G9Q The crystal structure of the glycogen phosphorylase b- 1AB complex Deposited 2006-03-07 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 6 1AB 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 2.50 Å R-free 0.243 |
| 2G9R The crystal structure of glycogen phosphorylase b in complex with (3R,4R,5R)-5-hydroxymethyl-1-(3-phenylpropyl)-piperidine-3,4-diol Deposited 2006-03-07 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | G27 (3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 2.07 Å R-free 0.220 |
| 2G9U The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethyl-1-(3-phenylpropyl)-piperidine-3,4-diol and phosphate Deposited 2006-03-07 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 4 G27 (3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 2.15 Å R-free 0.218 |
| 2G9V The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethylpiperidine-3,4-diol and phosphate Deposited 2006-03-07 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 4 IFM 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 287K
|
Resolution 2.15 Å R-free 0.235 |
| 2GJ4 Structure of rabbit muscle glycogen phosphorylase in complex with ligand Deposited 2006-03-30 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
12–835（824 aa）
|
Not recorded | SO4 SULFATE ION × 16 PLR (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE × 2 2TH 2-CHLORO-N-[(1R,2R)-1-HYDROXY-2,3-DIHYDRO-1H-INDEN-2-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.7；289 K；1.1mM IMP, 1.1mM Spermine, 0mM BES, 2.9mM DTT, 0.1mM EDTA, pH 6.7, VAPOR DIFFUSION, SITTING DROP, temperature 289K
|
Resolution 1.60 Å R-free 0.226 |
| 2GM9 Structure of rabbit muscle glycogen phosphorylase in complex with thienopyrrole Deposited 2006-04-06 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
12–836（825 aa）
|
Not recorded | PLR (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE × 2 3TH 2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；289 K；1.1mM IMP
1.1mM Spermin
10mM BES
2.9mM DTT
0.1mM EDTA, pH 6.7, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.30 Å R-free 0.245 |
| 2GPA ALLOSTERIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG Deposited 1999-02-18 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；pH 6.7
|
Resolution 2.00 Å R-free 0.230 |
| 2GPB COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B Deposited 1990-06-04 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.30 Å |
| 2GPN 100 K STRUCTURE OF GLYCOGEN PHOSPHORYLASE AT 2.0 ANGSTROMS RESOLUTION Deposited 1998-03-26 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；THE PROTEIN WAS CRYSTALLIZED FROM 0.01 M BES, PH 6.7, 0.003 M DTT, 0.001 M SPERMINE, 0.0001 M EDTA, 0.02 % (W/V) SODIUM AZIDE AT 16 DEGREES C. THE CRYSTALS WERE CRYOPROTECTED WITH 25% (V/V) MPD (2-METHYL-2,4-PENTANEDIOL)., temperature 289K
|
Resolution 1.99 Å R-free 0.248 |
| 2IEG Crystal structure of rabbit muscle glycogen phosphorylase in complex with 3,4-dihydro-2-quinolone Deposited 2006-09-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
|
Not recorded | PLR (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE × 2 FRY (2S)-N-[(3S)-1-(2-AMINO-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-2-CHLORO-2H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.7；298 K；10mM BES, pH6.7, 0.1mM EDTA, VAPOR DIFFUSION, temperature 298K
|
Resolution 1.90 Å R-free 0.269 |
| 2IEI Crystal structure of rabbit muscle glycogen phosphorylase in complex with 3,4-dihydro-2-quinolone Deposited 2006-09-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
|
Not recorded | PLR (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE × 2 FRX (S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.7；298 K；10mM BES, 0.1mM EDTA, pH 6.7, VAPOR DIFFUSION, temperature 298K
|
Resolution 1.91 Å R-free 0.297 |
| 2OFF The crystal structure of Glycogen Phosphorylase b in complex with a potent allosteric inhibitor Deposited 2007-01-03 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | OFF 2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Bes 10mM, EDTA, DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.20 Å R-free 0.213 |
| 2PRI BINDING OF 2-DEOXY-GLUCOSE-6-PHOSPHATE TO GLYCOGEN PHOSPHORYLASE B Deposited 1998-12-11 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | D6G 2-deoxy-6-O-phosphono-alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；293 K；THE PROTEIN WAS CRYSTALLISED FROM 10 MM BES, PH 6.7, 3 MM DITHIOTHREITOL, 0.1 MM EDTA, 0.02% SODIUM AZIDE. THE CRYSTALS WERE THEN SOAKED FOR ONE HOUR IN 100 MM 2-DEOXY-D-GLUCOSE-6-PHOSPHATE., VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.30 Å R-free 0.246 |
| 2PRJ Binding of N-acetyl-beta-D-glucopyranosylamine to Glycogen Phosphorylase B Deposited 1998-12-11 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | NBG N-acetyl-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；289 K；GLYCOGEN PHOSPHORYLASE WAS CO-CRYSTALLISED WITH 20 MM N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE IN A MEDIUM CONSISTING OF 20-30 MG/ML ENZYME, 1 MM IMP, 1 MM SPERMINE, 10 MM BES, 3 MM DITHIOTHREITOL, 0.1 MM EDTA, 0.02% (W/V) SODIUM AZIDE, PH 6.7 AT 16 C, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.30 Å R-free 0.237 |
| 2PYD The crystal structure of Glycogen phosphorylase in complex with glucose at 100 K Deposited 2007-05-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 DMS DIMETHYL SULFOXIDE × 36 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 MM BES BUFFER, 0.1 MM EDTA,0.02% NAN3, 3 MM DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.93 Å R-free 0.235 |
| 2PYD The crystal structure of Glycogen phosphorylase in complex with glucose at 100 K Deposited 2007-05-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 1 DMS DIMETHYL SULFOXIDE × 18 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 MM BES BUFFER, 0.1 MM EDTA,0.02% NAN3, 3 MM DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.93 Å R-free 0.235 |
| 2PYI Crystal structure of Glycogen Phosphorylase in complex with glucosyl triazoleacetamide Deposited 2007-05-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DL8 N-[(4-PHENYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL]-BETA-D-GLUCOPYRANOSYLAMINE × 2 DMS DIMETHYL SULFOXIDE × 20 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 MM BES BUFFER, 0.1 MM EDTA, 0.02% NAN3, 3 MM DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.88 Å R-free 0.238 |
| 2PYI Crystal structure of Glycogen Phosphorylase in complex with glucosyl triazoleacetamide Deposited 2007-05-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DL8 N-[(4-PHENYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL]-BETA-D-GLUCOPYRANOSYLAMINE × 1 DMS DIMETHYL SULFOXIDE × 10 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 MM BES BUFFER, 0.1 MM EDTA, 0.02% NAN3, 3 MM DTT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.88 Å R-free 0.238 |
| 2QLM Glycogen phosphorylase in complex with FN67 Deposited 2007-07-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | F68 N-{[(4-methylphenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.10 Å R-free 0.214 |
| 2QLN Glycogen Phosphorylase b in complex with N-4-phenylbenzoyl-N'-beta-D-glucopyranosyl urea Deposited 2007-07-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | F59 N-[(biphenyl-4-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.15 Å R-free 0.209 |
| 2QN1 Glycogen Phosphorylase b in complex with asiatic acid Deposited 2007-07-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 0AS asiatic acid × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.40 Å R-free 0.208 |
| 2QN2 Glycogen Phosphorylase b in complex with Maslinic Acid Deposited 2007-07-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 0MA maslinic acid × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.70 Å R-free 0.223 |
| 2QN3 Glycogen Phosphorylase in complex with N-4-chlorobenzoyl-N-beta-D-glucopyranosyl urea Deposited 2007-07-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | F55 N-{[(4-chlorophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.96 Å R-free 0.206 |
| 2QN7 Glycogen Phosphorylase b in complex with N-4-hydroxybenzoyl-N'-4-beta-D-glucopyranosyl urea Deposited 2007-07-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 HBZ N-{[(4-hydroxyphenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.83 Å R-free 0.230 |
| 2QN8 Glycogen Phosphorylase b in complex with N-4-nitrobenzoyl-N'-beta-D-glucopyranosyl urea Deposited 2007-07-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | SO4 SULFATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 NBY N-{[(4-nitrophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.90 Å R-free 0.197 |
| 2QN9 Glycogen Phosphorylase in complex with N-4-aminobenzoyl-N'-beta-D-glucopyranosyl urea Deposited 2007-07-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 NBX N-{[(4-aminophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.205 |
| 2QNB Glycogen Phosphorylase b in complex with N-benzoyl-N'-beta-D-glucopyranosyl urea Deposited 2007-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | BZD N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.80 Å R-free 0.220 |
| 2QRG Glycogen Phosphorylase b in complex with (1R)-3'-(4-methoxyphenyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] Deposited 2007-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | M07 (5R,7R,8S,9S,10R)-7-(HYDROXYMETHYL)-3-(4-METHOXYPHENYL)-1,6-DIOXA-2-AZASPIRO[4.5]DEC-2-ENE-8,9,10-TRIOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT , pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.85 Å R-free 0.211 |
| 2QRH Glycogen Phosphorylase b in complex with (1R)-3'-phenylspiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] Deposited 2007-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | M08 (5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-phenyl-1,6-dioxa-2-azaspiro[4.5]dec-2-ene-8,9,10-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT , pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.83 Å R-free 0.212 |
| 2QRM Glycogen Phosphorylase b in complex with (1R)-3'-(4-nitrophenyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] Deposited 2007-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | M09 (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-nitrophenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.90 Å R-free 0.224 |
| 2QRP Glycogen Phosphorylase b in complex with (1R)-3'-(2-naphthyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] Deposited 2007-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | S06 (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol × 2 DMS DIMETHYL SULFOXIDE × 30 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.86 Å R-free 0.219 |
| 2QRQ Glycogen Phosphorylase b in complex with (1R)-3'-(4-methylphenyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] Deposited 2007-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | S13 (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol × 2 DMS DIMETHYL SULFOXIDE × 32 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM Bes buffer, 3 mM DDT, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.80 Å R-free 0.230 |
| 2SKC PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH FLUOROPHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE Deposited 1998-12-11 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 FPO FLUORO-PHOSPHITE ION × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；289 K；T-STATE PYRIDOXAL PHOSPHORYLASE B, FROM RABBIT MUSCLE, WAS CO-CRYSTALLIZED WITH 8-10 MM FLUOROPHOSPHATE IN A MEDIUM CONSISTING OF 15-25 MG/ML ENZYME, 2 MM IMP, 2 MM SPERMINE, 50 MM GLUCOSE, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEGREE C). JUST BEFORE DATA COLLECTION, THE CRYSTALS WERE TRANSFERRED TO A FRESH BUFFER SOLUTION, CONTAINING THE SAME CONSTITUENTS AS THEIR MOTHER LIQUOR WITH THE EXCEPTION OF THE PROTEIN., VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.40 Å R-free 0.217 |
| 2SKD PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE Deposited 1998-12-11 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | GLC alpha-D-glucopyranose × 2 PO4 PHOSPHATE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；289 K；T-STATE PYRIDOXAL PHOSPHORYLASE B, FROM RABBIT MUSCLE, WAS CO-CRYSTALLIZED WITH 8-10 MM FLUOROPHOSPHATE IN A MEDIUM CONSISTING OF 15-25 MG/ML ENZYME, 2 MM IMP, 2 MM SPERMINE, 50 MM GLUCOSE, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEGREE C). JUST BEFORE DATA COLLECTION, THE CRYSTALS WERE TRANSFERRED TO A FRESH BUFFER SOLUTION, CONTAINING THE SAME CONSTITUENTS AS THEIR MOTHER LIQUOR WITH THE EXCEPTION OF THE PROTEIN., temperature 289K
|
Resolution 2.40 Å R-free 0.219 |
| 2SKE PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHITE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE Deposited 1998-12-11 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | GLC alpha-D-glucopyranose × 2 PO3 PHOSPHITE ION × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.7；289 K；T-STATE PYRIDOXAL PHOSPHORYLASE B, FROM RABBIT MUSCLE, WAS CO-CRYSTALLIZED WITH 8-10 MM FLUOROPHOSPHATE IN A MEDIUM CONSISTING OF 15-25 MG/ML ENZYME, 2 MM IMP, 2 MM SPERMINE, 50 MM GLUCOSE, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (16 DEGREE C). JUST BEFORE DATA COLLECTION, THE CRYSTALS WERE TRANSFERRED TO A FRESH BUFFER SOLUTION, CONTAINING THE SAME CONSTITUENTS AS THEIR MOTHER LIQUOR WITH THE EXCEPTION OF THE PROTEIN., VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.46 Å R-free 0.218 |
| 3AMV ALLOSTERIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG Deposited 1999-02-18 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 BIN 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.7；1 MM W1807 IN A MEDIUM CONSISTING OF 20-24 MG/ML ENZYME, 10 MM MAGNESIUM
ACETATE, 3 MM DTT, 10 MM BES, 0.1 MM EDTA, AND 0.02% SODIUM AZIDE, PH 6.7 (22
DEG C).
|
Resolution 2.10 Å R-free 0.260 |
| 3BCR Glycogen Phosphorylase b in complex with AZT Deposited 2007-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | AZZ 3'-azido-3'-deoxythymidine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.14 Å R-free 0.219 |
| 3BCS Glycogen Phosphorylase complex with 1(-D-glucopyranosyl) uracil Deposited 2007-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CJB 1-beta-D-glucopyranosylpyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.221 |
| 3BCU Glucogen Phosphorylase complex with thymidine Deposited 2007-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | THM THYMIDINE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.202 |
| 3BD6 Glycogen Phosphorylase complex with 1(-D-ribofuranosyl) cyanuric acid Deposited 2007-11-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | RDD 1-beta-D-ribofuranosyl-1,3,5-triazinane-2,4,6-trione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.205 |
| 3BD7 Glycogen Phosphorylase complex with 1(-D-glucopyranosyl) thymine Deposited 2007-11-14 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CKB 1-beta-D-glucopyranosyl-5-methylpyrimidine-2,4(1H,3H)-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 1.90 Å R-free 0.205 |
| 3BD8 Glucogen Phosphorylase complex with 1(-D-glucopyranosyl) cytosine Deposited 2007-11-14 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 C3B 4-amino-1-beta-D-glucopyranosylpyrimidin-2(1H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM Bes buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.10 Å R-free 0.211 |
| 3BDA Glycogen Phosphorylase complex with 1(-D-glucopyranosyl) cyanuric acid Deposited 2007-11-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | C4B 1-beta-D-glucopyranosyl-1,3,5-triazinane-2,4,6-trione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, 3mM DDT, pH6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.210 |
| 3CUT Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamide Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 179 N-[(naphthalen-2-ylamino)(oxo)acetyl]-beta-D-glucopyranosylamine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.30 Å R-free 0.220 |
| 3CUT Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamide Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 179 N-[(naphthalen-2-ylamino)(oxo)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.30 Å R-free 0.220 |
| 3CUU Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 376 N-[(naphthalen-1-ylamino)(oxo)acetyl]-beta-D-glucopyranosylamine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.30 Å R-free 0.218 |
| 3CUU Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 376 N-[(naphthalen-1-ylamino)(oxo)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.30 Å R-free 0.218 |
| 3CUV Tracking structure activity relationships of glycogen phosphorylase inhibitors: synthesis, kinetic and crystallographic evaluation of analogues of N-(-D-glucopyranosyl)-N'-oxamides Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 475 N-[oxo(pyridin-2-ylamino)acetyl]-beta-D-glucopyranosylamine × 1 DMS DIMETHYL SULFOXIDE × 15 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 1.93 Å R-free 0.231 |
| 3CUW Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 445 N-[oxo(phenylamino)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.00 Å R-free 0.216 |
| 3CUW Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides Deposited 2008-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 445 N-[oxo(phenylamino)acetyl]-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；287 K；BES, EDTA, pH6.7, SMALL TUBES, temperature 287K
|
Resolution 2.00 Å R-free 0.216 |
| 3E3L The R-state Glycogen Phosphorylase Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
Chain B
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 7.5；289 K；1.1-1.3 M ammonium sulfate, 10mM beta-glycerophosphate buffer pH 7.5, 0.5mM EDTA, SMALL TUBES, temperature 289K
|
Resolution 2.59 Å R-free 0.266 |
| 3E3L The R-state Glycogen Phosphorylase Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–843（842 aa）
Chain D
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 7.5；289 K；1.1-1.3 M ammonium sulfate, 10mM beta-glycerophosphate buffer pH 7.5, 0.5mM EDTA, SMALL TUBES, temperature 289K
|
Resolution 2.59 Å R-free 0.266 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
Chain B
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 2 SO4 SULFATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–843（842 aa）
Chain D
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 2 SO4 SULFATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–843（842 aa）
Chain F
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 2 SO4 SULFATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain G
2–843（842 aa）
Chain H
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 2 SO4 SULFATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
2–843（842 aa）
Chain B
2–843（842 aa）
Chain C
2–843（842 aa）
Chain D
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 4 SO4 SULFATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3N The Glycogen phosphorylase b R state- AMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain E
2–843（842 aa）
Chain F
2–843（842 aa）
Chain G
2–843（842 aa）
Chain H
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | AMP ADENOSINE MONOPHOSPHATE × 4 SO4 SULFATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.2-1.4 M ammonium sulphate, pH 7.5, MICRODIALYSIS, temperature 289K
|
Resolution 2.70 Å R-free 0.256 |
| 3E3O Glycogen phosphorylase R state-IMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
Chain B
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 4 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.1-1.3M ammonium sulfate, 10mM beta-glycerophosphate buffer pH 7.5, 0.5mM EDTA, MICRODIALYSIS, temperature 289K
|
Resolution 2.60 Å R-free 0.267 |
| 3E3O Glycogen phosphorylase R state-IMP complex Deposited 2008-08-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–843（842 aa）
Chain D
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 4 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
MICRODIALYSIS；pH 7.5；289 K；1.1-1.3M ammonium sulfate, 10mM beta-glycerophosphate buffer pH 7.5, 0.5mM EDTA, MICRODIALYSIS, temperature 289K
|
Resolution 2.60 Å R-free 0.267 |
| 3EBO Glycogen Phosphorylase b/Chrysin complex Deposited 2008-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 57D chrysin × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；286 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 286K
|
Resolution 1.90 Å R-free 0.220 |
| 3EBP Glycogen Phosphorylase b/flavopiridol complex Deposited 2008-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CPB 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；BES, EDTA, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.215 |
| 3G2H Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | KOT 1-beta-D-glucopyranosyl-4-phenyl-1H-1,2,3-triazole × 1 DMS DIMETHYL SULFOXIDE × 1 IMP INOSINIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.220 |
| 3G2H Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | KOT 1-beta-D-glucopyranosyl-4-phenyl-1H-1,2,3-triazole × 2 DMS DIMETHYL SULFOXIDE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.03 Å R-free 0.220 |
| 3G2I Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazole Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | RUG 1-beta-D-glucopyranosyl-4-(hydroxymethyl)-1H-1,2,3-triazole × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.00 Å R-free 0.225 |
| 3G2I Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazole Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | RUG 1-beta-D-glucopyranosyl-4-(hydroxymethyl)-1H-1,2,3-triazole × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.00 Å R-free 0.225 |
| 3G2J Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 9GP N-(hydroxyacetyl)-beta-D-glucopyranosylamine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.14 Å R-free 0.225 |
| 3G2J Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 9GP N-(hydroxyacetyl)-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.14 Å R-free 0.225 |
| 3G2K Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazole Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | SKY 1-beta-D-glucopyranosyl-4-naphthalen-2-yl-1H-1,2,3-triazole × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.00 Å R-free 0.224 |
| 3G2K Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazole Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | SKY 1-beta-D-glucopyranosyl-4-naphthalen-2-yl-1H-1,2,3-triazole × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.00 Å R-free 0.224 |
| 3G2L Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | LEW 1-beta-D-glucopyranosyl-4-naphthalen-1-yl-1H-1,2,3-triazole × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.30 Å R-free 0.210 |
| 3G2L Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | LEW 1-beta-D-glucopyranosyl-4-naphthalen-1-yl-1H-1,2,3-triazole × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；pH 6.8, SMALL TUBES, temperature 289K
|
Resolution 2.30 Å R-free 0.210 |
| 3G2N Crystal structure of N-acylglucosylamine with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | OAK N-(phenylcarbonyl)-beta-D-glucopyranosylamine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.10 Å R-free 0.227 |
| 3G2N Crystal structure of N-acylglucosylamine with glycogen phosphorylase Deposited 2009-01-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | OAK N-(phenylcarbonyl)-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；292 K；pH 6.8, SMALL TUBES, temperature 292K
|
Resolution 2.10 Å R-free 0.227 |
| 3GPB COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B Deposited 1990-06-04 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | G1P 1-O-phosphono-alpha-D-glucopyranose × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.30 Å |
| 3L79 Crystal Structure of Glycogen Phosphorylase DK1 complex Deposited 2009-12-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DKX 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10MM BES BUFFER, 3MM DDT, pH 6.7, small tubes, temperature 289K
|
Resolution 1.86 Å R-free 0.208 |
| 3L7A Crystal Structure of Glycogen Phosphorylase DK2 complex Deposited 2009-12-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DKY 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10MM BES BUFFER, 3MM DDT, pH 6.7, small tubes, temperature 289K
|
Resolution 1.90 Å R-free 0.211 |
| 3L7B Crystal Structure of Glycogen Phosphorylase DK3 complex Deposited 2009-12-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DKZ 4-amino-1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)pyrimidin-2(1H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10MM BES BUFFER, 3MM DDT, pH 6.7, small tubes, temperature 289K
|
Resolution 2.00 Å R-free 0.215 |
| 3L7C Crystal Structure of Glycogen Phosphorylase DK4 complex Deposited 2009-12-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DK4 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10MM BES BUFFER, 3MM DDT, pH 6.7, small tubes, temperature 289K
|
Resolution 1.93 Å R-free 0.207 |
| 3L7D Crystal Structure of Glycogen Phosphorylase DK5 complex Deposited 2009-12-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DK5 1-(2,3-dideoxy-3-fluoro-beta-D-arabino-hexopyranosyl)-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10MM BES BUFFER, 3MM DDT, pH 6.7, small tubes, temperature 289K
|
Resolution 2.00 Å R-free 0.215 |
| 3MQF Glycogen phosphorylase complexed with 4-fluorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 20X N-({(2E)-2-[(4-fluorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA, 3 mM DTT. 20mM inhibitor in 20% DMSO soaked with T-state native enzyme crystal for 13 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.95 Å R-free 0.208 |
| 3MRT Glycogen phosphorylase complexed with 4-pyridinecarboxaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 12E N-{[(2E)-2-(pyridin-4-ylmethylidene)hydrazino]carbonothioyl}-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. 20mM inhibitor in 20% DMSO soaked with crystal for 7 hrs, SMALL TUBES, temperature 289K
|
Resolution 1.98 Å R-free 0.216 |
| 3MRV Glycogen phosphorylase complexed with 3-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 16F N-({(2Z)-2-[(3-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 DMS DIMETHYL SULFOXIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20mM inhibitor in 20% DMSO soaked with T-state native enzyme crystals for 3.5 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.94 Å R-free 0.216 |
| 3MRX Glycogen phosphorylase complexed with 4-methoxybenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 17S N-({(2E)-2-[(4-methoxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. 6.7mM inhibitor in 20% DMSO soaked with native crystals for 3 hrs, SMALL TUBES, temperature 289K
|
Resolution 1.95 Å R-free 0.216 |
| 3MS2 Glycogen phosphorylase complexed with 4-methylbenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 18S N-({(2E)-2-[(4-methylphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. 20mM inhibitor in 20% DMSO soaked native crystal for 3.5 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.10 Å R-free 0.223 |
| 3MS4 Glycogen phosphorylase complexed with 4-trifluoromethylbenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 21N N-{[(2E)-2-{[4-(trifluoromethyl)phenyl]methylidene}hydrazino]carbonothioyl}-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA, 3 mM DTT. Crystals were soaked with 10mM inhibitor in 20% DMSO for 7 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.07 Å R-free 0.235 |
| 3MS7 Glycogen phosphorylase complexed with 2-chlorobenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl) thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 22S N-({(2E)-2-[(2-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. 20mM inhibitor in 20% DMSO soaked with T-state native enzyme crystal for 11.5 hrs, SMALL TUBES, temperature 289K
|
Resolution 1.95 Å R-free 0.215 |
| 3MSC Glycogen phosphorylase complexed with 2-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 24S N-({(2Z)-2-[(2-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. 5mM inhibitor in 20% DMSO soaked with native crystal for 18 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.95 Å R-free 0.214 |
| 3MT7 Glycogen phosphorylase complexed with 4-bromobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 16O N-({(2E)-2-[(4-bromophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. Soaking: 20mM inhibitor in 20% DMSO soaked with crystal for 15.75 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.209 |
| 3MT8 Glycogen phosphorylase complexed with 4-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 17T N-({(2E)-2-[(4-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml protein in a buffer of 10 mM BES, pH 6.7, 1mM EDTA, 3mM DTT. Crystals soaked with 20mM inhibitor in 20% DMSO for 21 hrs, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.214 |
| 3MT9 Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 18O N-({(2E)-2-[(4-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. Crystals soaked with 6.7mM inhibitor in 20% DMSO for 3 hrs, SMALL TUBES, temperature 289K
|
Resolution 2.05 Å R-free 0.205 |
| 3MTA Glycogen phosphorylase complexed with 3-bromobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 22O N-({(2E)-2-[(3-bromophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml protein in a buffer of 10 mM BES, pH 6.7, 1mM EDTA, 3mM DTT. Crystals soaked with 10mM inhibitor in 20% DMSO soaked for 21 hrs, SMALL TUBES, temperature 289K
|
Resolution 2.23 Å R-free 0.233 |
| 3MTB Glycogen phosphorylase complexed with 3-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 23V N-({(2E)-2-[(3-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. Crystal soaked with 20mM inhibitor in 20% DMSO for 16 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.95 Å R-free 0.212 |
| 3MTD Glycogen phosphorylase complexed with 4-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone Deposited 2010-04-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 25E N-({(2Z)-2-[(4-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. Crystal soaked with 20mM inhibitor in 20% DMSO for 21hrs 15 min, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.10 Å R-free 0.214 |
| 3NC4 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Deposited 2010-06-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
3–843（841 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26O N-({(2E)-2-[(2-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；Crystals grown from 20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA, 3 mM DTT. Crystals were soaked with 20mM inhibitor in 20% DMSO for 21 hrs 10 mins, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.07 Å R-free 0.220 |
| 3NP7 Glycogen phosphorylase complexed with 2,5-dihydroxy-3-(beta-D-glucopyranosyl)-chlorobenzene and 2,5-dihydroxy-4-(beta-D-glucopyranosyl)-chlorobenzene Deposited 2010-06-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | Z15 (1S)-1,5-anhydro-1-(4-chloro-2,5-dihydroxyphenyl)-D-glucitol × 4 Z16 (1S)-1,5-anhydro-1-(3-chloro-2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/ml of protein in a buffer solution containing 10 mM BES pH 6.7, 1 mM EDTA and 3 mM DTT. Crystals soaked with 100 mM inhibitor in BES for 21 hours, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.05 Å R-free 0.220 |
| 3NP9 Glycogen phosphorylase complexed with 3-(beta-D-glucopyranosyl)-2-hydroxy-5-methoxy-chlorobenzene Deposited 2010-06-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | Z2T (1S)-1,5-anhydro-1-(3-chloro-2-hydroxy-5-methoxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg.ml protein in 10 mM BES, 0.5 mM EDTA, 3 mM DTT. T-state GPb crystals soaked with 10 mM inhibitor for 2.5 hours, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.214 |
| 3NPA Glycogen phosphorylase complexed with 2,5-dihydroxy-4-(beta-D-glucopyranosyl)-bromo-benzene Deposited 2010-06-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | Z57 (1S)-1,5-anhydro-1-(4-bromo-2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；20 mg/mL protein in a buffer consisting of 10 mM BES, 0.5 mM EDTA, 3 mM DTT. T-state GPb crystals soaked with 20 mM inhibitor for 6 hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.97 Å R-free 0.213 |
| 3S0J The crystal structure of glycogen phosphorylase b in complex with 2,5-dihydroxy-4-(beta-D-glucopyranosyl)-chlorobenzene Deposited 2011-05-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | Z15 (1S)-1,5-anhydro-1-(4-chloro-2,5-dihydroxyphenyl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES Buffer, 3 mM DTT, 1 mM IMP, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.209 |
| 3SYM Glycogen Phosphorylase b in complex with 3 -C-(hydroxymethyl)-beta-D-glucopyranonucleoside of 5-fluorouracil Deposited 2011-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GP0 5-fluoro-1-[3-C-(hydroxymethyl)-beta-D-glucopyranosyl]pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；2mM INHIBITOR SOAKED WITH
T-STATE NATIVE ENZYME CRYSTAL FOR 2 HRS, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.40 Å R-free 0.203 |
| 3SYR Glycogen phosphorylase b in complex with beta-D-glucopyranonucleoside 5-fluorouracil Deposited 2011-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GPK 5-fluoro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；2mM INHIBITOR SOAKED WITH T-STATE NATIVE ENZYME CRYSTAL FOR 2 HRS, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.40 Å R-free 0.217 |
| 3T3D Glycogen phosphorylase b in complex with GlcU Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CJB 1-beta-D-glucopyranosylpyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；T state crystals soaked with 2 mM solution of the inhibitor in the crystallization media for 2hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.50 Å R-free 0.223 |
| 3T3E Glycogen phosphorylase b in complex with GlcClU Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GPQ 5-chloro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；T state crystals soaked with 2 mM solution of the inhibitor in the crystallization media for 2hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.15 Å R-free 0.233 |
| 3T3G Glycogen Phosphorylase b in complex with GlcBrU Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GPU 5-bromo-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；T state crystals soaked with 2 mM solution of the inhibitor in the crystallization media for 2hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.40 Å R-free 0.235 |
| 3T3H Glycogen Phosphorylase b in complex with GlcIU Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GPV 1-(beta-D-glucopyranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；T state crystals soaked with 2 mM solution of the inhibitor in the crystallization media for 2hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.60 Å R-free 0.221 |
| 3T3I Glycogen Phosphorylase b in complex with GlcCF3U Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GPW 1-(beta-D-glucopyranosyl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；T state crystals soaked with 2 mM solution of the inhibitor in the crystallization media for 2hrs, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.65 Å R-free 0.235 |
| 3ZCP Rabbit muscle glycogen phosphorylase b in complex with N- cyclohexancarbonyl-N-beta-D-glucopyranosyl urea determined at 1.83 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 F58 N-[(cyclohexylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 1.83 Å R-free 0.211 |
| 3ZCQ Rabbit muscle glycogen phosphorylase b in complex with N-(4- trifluoromethyl-benzoyl)-N-beta-D-glucopyranosyl urea determined at 2. 15 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 62N N-{[4-(trifluoromethyl)benzoyl]carbamoyl}-beta-D-glucopyranosylamine × 2 PO4 PHOSPHATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 2.15 Å R-free 0.217 |
| 3ZCR Rabbit muscle glycogen phosphorylase b in complex with N-(4-tert- butyl-benzoyl)-N-beta-D-glucopyranosyl urea determined at 2.07 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | IMP INOSINIC ACID × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 F85 N-[(4-tert-butylbenzoyl)carbamoyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 2.07 Å R-free 0.208 |
| 3ZCS Rabbit muscle glycogen phosphorylase b in complex with N-(1-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.07 A resolution Deposited 2012-11-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Mutation：YES | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 CAW N-[[(2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]carbamoyl]naphthalene-1-carboxamide × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 2.03 Å R-free 0.217 |
| 3ZCT Rabbit muscle glycogen phosphorylase b in complex with N-(2-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.0 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 VMP N-[[(2R,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]carbamoyl]naphthalene-2-carboxamide × 4 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 2.00 Å R-free 0.208 |
| 3ZCU Rabbit muscle glycogen phosphorylase b in complex with N-(pyridyl-2- carbonyl)-N-beta-D-glucopyranosyl urea determined at 2.05 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | T68 N-[(pyridin-2-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 2.05 Å R-free 0.216 |
| 3ZCV Rabbit muscle glycogen phosphorylase b in complex with N-(indol-2- carbonyl)-N-beta-D-glucopyranosyl urea determined at 1.8 A resolution Deposited 2012-11-21 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | N85 N-[(1H-indol-2-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 SO4 SULFATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 1.83 Å R-free 0.216 |
| 4CTM Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods Deposited 2014-03-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | MIF (5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2-imino-6-oxa-1-thia-3-azaspiro[4.5]decan-4-one × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 PO4 PHOSPHATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；25MG/ML ENZYME, 1MM SPERMINE, 10MM BES, 3MM DTT, 0.1MM EDTA, 0.02% SODIUM AZIDE, PH 6.7
|
Resolution 1.95 Å R-free 0.196 |
| 4CTN Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods Deposited 2014-03-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | DTT 2,3-DIHYDROXY-1,4-DITHIOBUTANE × 2 DMS DIMETHYL SULFOXIDE × 2 M8P N-[(2Z,5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-4-oxo-6-oxa-1-thia-3-azaspiro[4.5]dec-2-ylidene]naphthalene-2-carboxamide × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；25MG/ML ENZYME, 1MM SPERMINE, 10MM BES, 3MM DTT, 0.1MM EDTA, PH 6.7, AT 16OC.
|
Resolution 2.10 Å R-free 0.218 |
| 4CTO Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods Deposited 2014-03-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | M7C N-[(2Z,5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-4-oxo-6-oxa-1-thia-3-azaspiro[4.5]dec-2-ylidene]benzamide × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 PO4 PHOSPHATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；289 K；25MG/ML ENZYME, 1MM SPERMINE, 10MM BES, 3MM DTT, 0.1MM EDTA, PH 6.7, AT 16 DEGREES C.
|
Resolution 1.90 Å R-free 0.193 |
| 4EJ2 Crystal structure of GPb in complex with DK10 Deposited 2012-04-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | D1F 1-(beta-D-glucopyranosyl)-5-(hept-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.65 Å R-free 0.233 |
| 4EKE Crystal structure of GPb in complex with DK11 Deposited 2012-04-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | D1I 3-(beta-D-glucopyranosyl)-6-pentylfuro[2,3-d]pyrimidin-2(3H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.60 Å R-free 0.231 |
| 4EKY Crystal structure of GPb in complex with DK15 Deposited 2012-04-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | D1J 1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.45 Å R-free 0.230 |
| 4EL0 Crystal structure of GPb in complex with DK16 Deposited 2012-04-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | D1K 3-(beta-D-glucopyranosyl)-6-propylfuro[2,3-d]pyrimidin-2(3H)-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.40 Å R-free 0.218 |
| 4EL5 Crystal structure of GPb in complex with DK12 Deposited 2012-04-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | D1M 5-ethynyl-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.210 |
| 4GPB COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B Deposited 1990-06-04 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GFP 2-deoxy-2-fluoro-1-O-phosphono-alpha-D-glucopyranose × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.30 Å |
| 4MHO Crystal structure of Gpb in complex with S3, SUGAR (N-[(BIPHENYL-4-YLOXY)ACETYL]-BETA-D-GLUCOPYRANOSYLAMINE) Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
Fragment：unp residues 13-837
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26M N-[(biphenyl-4-yloxy)acetyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.200 |
| 4MHS Crystal structure of Gpb in complex with SUGAR (N-[(2E)-3-(BIPHENYL-4-YL)PROP-2-ENOYL]-BETA-D-GLUCOPYRANOSYLAMINE Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
Fragment：unp residues 13-837
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26Q N-[(2E)-3-(biphenyl-4-yl)prop-2-enoyl]-beta-D-glucopyranosylamine × 2 DMS DIMETHYL SULFOXIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.00 Å R-free 0.189 |
| 4MI3 Crystal structure of Gpb in complex with SUGAR (N-{(2R)-2-METHYL-3-[4-(PROPAN-2-YL)PHENYL]PROPANOYL}-BETA-D-GLUCOPYRANOSYLAMINE) (S21) Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
Fragment：unp residues 13-837
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26R N-{(2R)-2-methyl-3-[4-(propan-2-yl)phenyl]propanoyl}-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.15 Å R-free 0.203 |
| 4MI6 Crystal structure of Gpb in complex with SUGAR (N-[4-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)BUTANOYL]-BETA-D-GLUCOPYRANOSYLAMINE) Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
Fragment：unp residues 13-837
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26V N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)butanoyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.90 Å R-free 0.189 |
| 4MI9 Crystal structure of Gpb in complex with SUGAR (N-[(3R)-3-(4-ETHYLPHENYL)BUTANOYL]-BETA-D-GLUCOPYRANOSYLAMINE) (S20) Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
Fragment：unp residues 13-837
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26W N-[(3R)-3-(4-ethylphenyl)butanoyl]-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 1.85 Å R-free 0.190 |
| 4MIC Crystal structure of Gpb in complex with SUGAR (N-{(2E)-3-[4-(PROPAN-2-YL)PHENYL]PROP-2-ENOYL}-BETA-D-GLUCOPYRANOSYLAMINE) (S6) Deposited 2013-08-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 26Y N-{(2E)-3-[4-(propan-2-yl)phenyl]prop-2-enoyl}-beta-D-glucopyranosylamine × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.45 Å R-free 0.234 |
| 4MRA Crystal structure of Gpb in complex with QUERCETIN Deposited 2013-09-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | QUE 3,5,7,3',4'-PENTAHYDROXYFLAVONE × 2 DMS DIMETHYL SULFOXIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer, pH 6.7, SMALL TUBES, temperature 289K
|
Resolution 2.34 Å R-free 0.244 |
| 4YI3 Crystal structure of Gpb in complex with 4a Deposited 2015-02-27 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 4D0 N-{[3-(biphenyl-4-yl)propanoyl]carbamoyl}-beta-D-glucopyranosylamine × 1 IMP INOSINIC ACID × 1 DMS DIMETHYL SULFOXIDE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES buffer
|
Resolution 1.80 Å R-free 0.198 |
| 4YI5 Crystal structure of Gpb in complex with 4b Deposited 2015-02-27 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 4D1 N-({(2E)-3-[4-(propan-2-yl)phenyl]prop-2-enoyl}carbamoyl)-beta-D-glucopyranosylamine × 1 IMP INOSINIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES buffer
|
Resolution 1.80 Å R-free 0.230 |
| 4YUA Glycogen phosphorylase in complex with ellagic acid Deposited 2015-03-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 REF 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES buffer
|
Resolution 2.00 Å R-free 0.202 |
| 4Z5X Glycogen phosphorylase in complex with gallic acid Deposited 2015-04-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GDE 3,4,5-trihydroxybenzoic acid × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES BUFFER
|
Resolution 2.10 Å R-free 0.189 |
| 5GPB COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B Deposited 1990-06-04 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | GPM (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.30 Å |
| 5JTT Crystal structure of GPb in complex with 8a Deposited 2016-05-09 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 6MY (1S)-1,5-anhydro-1-(5-phenyl-1H-imidazol-2-yl)-D-glucitol × 2 DMS DIMETHYL SULFOXIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer
|
Resolution 1.85 Å R-free 0.188 |
| 5JTU Crystal structure of GPb in complex with 8b Deposited 2016-05-09 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 6NE (1S)-1,5-anhydro-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]-D-glucitol × 2 DMS DIMETHYL SULFOXIDE × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10mM BES buffer
|
Resolution 1.85 Å R-free 0.203 |
| 5LRC Crystal structure of Glycogen Phosphorylase in complex with KS114 Deposited 2016-08-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 73E (1S)-1,5-anhydro-1-(5-phenyl-4H-1,2,4-triazol-3-yl)-D-glucitol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM Bes buffer
|
Resolution 2.00 Å R-free 0.197 |
| 5LRD Crystal structure of Glycogen Phosphorylase b in complex with KS242 Deposited 2016-08-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KS2 (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 DMS DIMETHYL SULFOXIDE × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES buffer
|
Resolution 1.80 Å R-free 0.187 |
| 5LRE Crystal structure of Glycogen Phosphorylase b in complex with KS382 Deposited 2016-08-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–843（842 aa）
|
Not recorded | KS3 (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 1 DMS DIMETHYL SULFOXIDE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SLOW COOLING；pH 6.8；289 K；10mM BES buffer
|
Resolution 1.80 Å R-free 0.186 |
| 5LRF Crystal structure of Glycogen Phosphorylase b in complex with KS389 Deposited 2016-08-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | KS3 (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol × 4 DMS DIMETHYL SULFOXIDE × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES buffer
|
Resolution 1.75 Å R-free 0.185 |
| 5MCB Glycogen phosphorylase in complex with chlorogenic acid. Deposited 2016-11-09 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
13–837（825 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 1 CGG Chlorogenic acid × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10mM BES Buffer
|
Resolution 1.95 Å R-free 0.177 |
| 5MEM A potent fluorescent inhibitor of glycogen phosphorylase as a catalytic site probe. Deposited 2016-11-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 7LS 2-[[1-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2-oxidanylidene-pyrimidin-4-yl]amino]-10~{H}-acridin-9-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.8；289 K；N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid, EDTA, DTT, IMP
|
Resolution 1.78 Å R-free 0.195 |
| 5O50 Glycogen Phosphorylase b in complex with 33a Deposited 2017-05-31 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 9L2 (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.161 |
| 5O52 Glycogen Phosphorylase b in complex with 33b Deposited 2017-05-31 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 9LE (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.158 |
| 5O54 Glycogen Phosphorylase b in complex with 29a Deposited 2017-05-31 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 9LB (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(5-phenyl-4~{H}-1,2,4-triazol-3-yl)oxane-3,4-diol × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.45 Å R-free 0.187 |
| 5O56 Glycogen Phosphorylase b in complex with 29b Deposited 2017-05-31 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 9L8 (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4-diol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.45 Å R-free 0.229 |
| 5OWY Glycogen Phosphorylase in complex with KS252 Deposited 2017-09-05 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 B0W 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.163 |
| 5OWZ Glycogen Phosphorylase in complex with KS172 Deposited 2017-09-05 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | IMP INOSINIC ACID × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 B0Z (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-[4-(trifluoromethyl)phenyl]-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.85 Å R-free 0.163 |
| 5OX0 Glycogen Phosphorylase in complex with CK898 Deposited 2017-09-05 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | B1H (1S)-1,5-anhydro-1-[3-(4-nitrophenyl)-1H-1,2,4-triazol-5-yl]-D-glucitol × 1 PLP PYRIDOXAL-5'-PHOSPHATE × 1 IMP INOSINIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.168 |
| 5OX1 Glycogen Phosphorylase in complex with JLH270 Deposited 2017-09-05 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | B1K (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methoxyphenyl)-1~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol × 2 DMS DIMETHYL SULFOXIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.85 Å R-free 0.169 |
| 5OX3 Glycogen Phosphorylase in complex with SzB102v Deposited 2017-09-05 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | B1N (1S)-1,5-anhydro-1-[3-(4-hydroxyphenyl)-1H-1,2,4-triazol-5-yl]-D-glucitol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.163 |
| 5OX4 Glycogen Phosphorylase in complex with CK900 Deposited 2017-09-05 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | B1W (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(4-aminophenyl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.80 Å R-free 0.167 |
| 6F3J The crystal structure of Glycogen Phosphorylase in complex with 10a Deposited 2017-11-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 CKQ 4-[4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]phenyl]benzoic acid × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.20 Å R-free 0.167 |
| 6F3L The crystal structure of Glycogen Phosphorylase in complex with 10b Deposited 2017-11-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CJW 6-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-1~{H}-1,2,4-triazol-3-yl]naphthalene-2-carboxylic acid × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.161 |
| 6F3R The crystal structure of Glycogen Phosphorylase in complex with 10c Deposited 2017-11-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CKZ (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(9~{H}-fluoren-2-yl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4,5-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.160 |
| 6F3S The crystal structure of Glycogen Phosphorylase in complex with 10d Deposited 2017-11-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 CKW (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-phenylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 1.90 Å R-free 0.156 |
| 6F3U The crystal structure of Glycogen Phosphorylase in complex with 10h Deposited 2017-11-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 CNK (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(5-naphthalen-1-yl-4~{H}-1,2,4-triazol-3-yl)oxane-3,4,5-triol × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.20 Å R-free 0.172 |
| 6GPB REFINED CRYSTAL STRUCTURE OF THE PHOSPHORYLASE-HEPTULOSE 2-PHOSPHATE-OLIGOSACCHARIDE-AMP COMPLEX Deposited 1990-06-04 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | H2P 1-deoxy-2-O-phosphono-alpha-D-gluco-hept-2-ulopyranose × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 AMP ADENOSINE MONOPHOSPHATE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.86 Å |
| 6QA6 Glycogen Phosphorylase b in complex with 30 Deposited 2018-12-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | DMS DIMETHYL SULFOXIDE × 2 HT8 (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-2-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one × 4 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.40 Å R-free 0.199 |
| 6QA7 Glycogen Phosphorylase b in complex with 29 Deposited 2018-12-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | HTW (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-1-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.36 Å R-free 0.191 |
| 6QA8 Glycogen Phosphorylase b in complex with 28 Deposited 2018-12-18 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | HTE (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-8,9,10-tris(oxidanyl)-2-phenyl-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.35 Å R-free 0.212 |
| 6R0H Glycogen Phosphorylase b in complex with 3 Deposited 2019-03-13 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | JN2 3-(4-fluorophenyl)-~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]benzamide × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.50 Å R-free 0.213 |
| 6R0I Glycogen Phosphorylase b in complex with 4 Deposited 2019-03-13 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | JNB ~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4-phenyl-benzamide × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.40 Å R-free 0.196 |
| 6S4H The crystal structure of glycogen phosphorylase in complex with 8 Deposited 2019-06-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KUQ (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-phenyl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol × 2 DMS DIMETHYL SULFOXIDE × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.45 Å R-free 0.188 |
| 6S4K The crystal structure of glycogen phosphorylase in complex with 12 Deposited 2019-06-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KVW (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(4-phenyl-1,3-thiazol-2-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.43 Å R-free 0.211 |
| 6S4O The crystal structure of glycogen phosphorylase in complex with 9 Deposited 2019-06-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KV5 (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.35 Å R-free 0.207 |
| 6S4P The crystal structure of glycogen phosphorylase in complex with 13 Deposited 2019-06-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KVE (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1,3-thiazol-2-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.37 Å R-free 0.214 |
| 6S4R The crystal structure of glycogen phosphorylase in complex with 11 Deposited 2019-06-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KVH (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1,3-thiazol-4-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.30 Å R-free 0.197 |
| 6S51 The crystal structure of glycogen phosphorylase in complex with 10 Deposited 2019-06-29 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KVQ (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-phenyl-1,3-thiazol-4-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.37 Å R-free 0.205 |
| 6S52 The crystal structure of glycogen phosphorylase in complex with 14 Deposited 2019-06-29 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | KVN (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(5-phenyl-1,2,3,4-tetrazol-2-yl)oxane-3,4,5-triol × 2 PLP PYRIDOXAL-5'-PHOSPHATE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.37 Å R-free 0.204 |
| 6Y55 The crystal structure of glycogen phosphorylase in complex with 43 Deposited 2020-02-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | O9Q 2-(3-methylphenyl)-5,7-bis(oxidanyl)chromen-4-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.38 Å R-free 0.211 |
| 6Y5C The crystal structure of glycogen phosphorylase in complex with 52 Deposited 2020-02-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | O9T 2-(4-methylphenyl)-5,7-bis(oxidanyl)chromen-4-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.40 Å R-free 0.211 |
| 6Y5O The crystal structure of glycogen phosphorylase in complex with 20 Deposited 2020-02-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | O9Z 2-(4-fluorophenyl)-5,7-bis(oxidanyl)chromen-4-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.7；289 K；10 mM BES buffer, pH 6.7
|
Resolution 2.33 Å R-free 0.212 |
| 6YVE Glycogen phosphorylase b in complex with pelargonidin 3-O-beta-D-glucoside Deposited 2020-04-28 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain AAA
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 DMS DIMETHYL SULFOXIDE × 2 PUQ pelargonidin 3-O-beta-D-glucoside × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.8；289 K；10mM BES buffer pH 6.7
|
Resolution 2.10 Å R-free 0.226 |
| 7GPB STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP Deposited 1990-11-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–842（842 aa）
Chain B
1–842（842 aa）
Chain C
1–842（842 aa）
Chain D
1–842（842 aa）
|
Not recorded | SO4 SULFATE ION × 7 PLP PYRIDOXAL-5'-PHOSPHATE × 4 AMP ADENOSINE MONOPHOSPHATE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.90 Å |
| 7ONF The binding of p-coumaroyl glucose to glycogen phosphorylase reveals the relationship between structural data and effects on cell metabolome Deposited 2021-05-25 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
13–837（825 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 IMP INOSINIC ACID × 2 VKK p-coumaroyl glucose × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 1.60 Å R-free 0.161 |
| 7P7D Rabbit muscle Glycogen Phosphorylase T state Deposited 2021-07-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
8–837（830 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DMS DIMETHYL SULFOXIDE × 42 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.7；289 K；10 mM BES buffer
|
Resolution 1.45 Å R-free 0.170 |
| 7Q5I A glucose-based molecular rotor probes the catalytic site of glycogen phosphorylase. Deposited 2021-11-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain AAA
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | I0F 2-cyano-3-[4-(dimethylamino)phenyl]-~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]propanamide × 2 CO3 CARBONATE ION × 6 BME BETA-MERCAPTOETHANOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.8；289 K；N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid, EDTA, DTT, IMP
|
Resolution 1.80 Å R-free 0.180 |
| 8BZS The crystal structure of glycogen phosphorylase in complex with baicalein Deposited 2022-12-15 | Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 3WL 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
SMALL TUBES；pH 6.8；289 K；10 mM BES buffer
|
Resolution 2.25 Å R-free 0.203 |
| 8GPB STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP Deposited 1990-11-13 | Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–842（842 aa）
|
Not recorded | PLP PYRIDOXAL-5'-PHOSPHATE × 2 AMP ADENOSINE MONOPHOSPHATE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.20 Å |
| 8QMU The complex of Glycogen Phosphorylase with (-)-Epigallocatechin-3-gallate (EGCG). Deposited 2023-09-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
8–837（830 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | KDH (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate × 2 DMS DIMETHYL SULFOXIDE × 46 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.7；289 K；10 mM BES pH 6.7
|
Resolution 2.00 Å R-free 0.208 |
| 8R52 The complex of Glycogen Phosphorylase with epigallocatechin (EGC). Deposited 2023-11-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
8–836（829 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DMS DIMETHYL SULFOXIDE × 44 EGT 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；289 K；10 mM BES buffer pH 6.7
|
Resolution 2.10 Å R-free 0.203 |
| 8R53 The complex of Glycogen Phosphorylase with (-)-Epigallocatechin-3-gallate (EGCG) and glucose. Deposited 2023-11-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
8–837（830 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | GLC alpha-D-glucopyranose × 2 DMS DIMETHYL SULFOXIDE × 52 KDH (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.7；289 K；10 mM BES buffer
|
Resolution 2.00 Å R-free 0.197 |
| 8R6V The complex of glycogen phosphorylase with EGCG (epigallocatechin gallate) and caffeine. Deposited 2023-11-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
8–837（830 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | DMS DIMETHYL SULFOXIDE × 58 KDH (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate × 2 CFF CAFFEINE × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.7；289 K；10mM BES buffer pH 6.7
|
Resolution 2.50 Å R-free 0.233 |
| 9FRM The crystal structure of glycogen phosphorylase with an indole derivative Deposited 2024-06-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–843（843 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | A1IFQ (7~{S})-1-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)amino]-6,6-dimethyl-7-oxidanyl-7,8-dihydrobenzo[cd]indole-3-carboxylic acid × 2 DMS DIMETHYL SULFOXIDE × 34 |
X-RAY DIFFRACTION
X-ray crystallization conditions
BATCH MODE；pH 6.7；289 K；10 mM BES
|
Resolution 2.00 Å R-free 0.215 |
| 9GPB THE ALLOSTERIC TRANSITION OF GLYCOGEN PHOSPHORYLASE Deposited 1990-12-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
2–843（842 aa）
Chain B
2–843（842 aa）
Chain C
2–843（842 aa）
Chain D
2–843（842 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 12 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.90 Å |
229 other PDB entries and 261 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | PHS2_RABIT |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–842； UniProt 1–842 |
