物种未注明
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 9 | HAEMADIN × 3 （Q25163） water × 9 | 与蛋白数一致 |
| UniProt名称 | THRB_HUMAN |
| Isoform | — |
| PDB实体 | 1, 2 |
| 链与序列区间 | 作者链 A； PDB构建体 1–36； UniProt 328–363 作者链 B； PDB构建体 1–36； UniProt 328–363 作者链 C； PDB构建体 1–36； UniProt 328–363 作者链 D； PDB构建体 1–259； UniProt 364–622 作者链 E； PDB构建体 1–259； UniProt 364–622 作者链 F； PDB构建体 1–259； UniProt 364–622 |
HAEMADIPSA SYLVESTRIS
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 9 | THROMBIN × 3 （P00734） THROMBIN × 3 （P00734） water × 9 | 与蛋白数一致 |
| UniProt名称 | Q25163 |
| Isoform | — |
| PDB实体 | 3 |
| 链与序列区间 | 作者链 I； PDB构建体 1–57； UniProt 21–77 作者链 J； PDB构建体 1–57； UniProt 21–77 作者链 K； PDB构建体 1–57； UniProt 21–77 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 1e0f |
| 沉积日期 deposition_date | 2000-03-27 |
| 结构标题 title | Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor |
| 关键词 keywords | COAGULATION/CRYSTAL STRUCTURE/HEPARIN-B, COAGULATION/CRYSTAL STRUCTURE/HEPARIN-BINDING SITE/ HIRUDIN/THROMBIN INHIBITOR, HYDROLASE; HYDROLASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 43.51 Å |
| Rg（电子密度） | 44.04 Å |
| 总 Rg | 43.96 Å |
| 原子数 | 8374 |
| 残基数 | 1048 |
| 排除体积 | 148390 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d1e0f.1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.2 — Eukaryotic proteases |
| 结构域编号 domain_id | d1e0f.2 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.2 — Eukaryotic proteases |
| 结构域编号 domain_id | d1e0f.3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.2 — Eukaryotic proteases |
| 结构域编号 domain_id | d1e0fi_ |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.15 — Leech antihemostatic proteins |
| 家族 Family family | g.3.15.2 — Hirudin-like |
| 结构域编号 domain_id | d1e0fj_ |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.15 — Leech antihemostatic proteins |
| 家族 Family family | g.3.15.2 — Hirudin-like |
| 结构域编号 domain_id | d1e0fk_ |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.15 — Leech antihemostatic proteins |
| 家族 Family family | g.3.15.2 — Hirudin-like |
| 结构域编号 domain_id | 1e0fD01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fD02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fE01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fE02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fF01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fF02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 1e0fI01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 70 — Distorted Sandwich |
| 拓扑 Topology topology | 10 — Thrombin Inhibitor (Hirudin); Chain I |
| 同源超家族 H-superfamily homologous superfamily | 10 — Thrombin Inhibitor (Hirudin), subunit I |
| 结构域编号 domain_id | 1e0fJ01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 70 — Distorted Sandwich |
| 拓扑 Topology topology | 10 — Thrombin Inhibitor (Hirudin); Chain I |
| 同源超家族 H-superfamily homologous superfamily | 10 — Thrombin Inhibitor (Hirudin), subunit I |
| 结构域编号 domain_id | 1e0fK01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 70 — Distorted Sandwich |
| 拓扑 Topology topology | 10 — Thrombin Inhibitor (Hirudin); Chain I |
| 同源超家族 H-superfamily homologous superfamily | 10 — Thrombin Inhibitor (Hirudin), subunit I |