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1eaq

The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding

Method: X-RAY DIFFRACTION Dmax: 81.1 Å Quality: GOOD

SAXS Profile

SAXS profile for 1eaq

P(r) Distribution

P(r) distribution for 1eaq

1. Structure Basics

entry_id1eaq
deposition_date2001-07-14
titleThe RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding
keywords;TRANSCRIPTION/DNA, ACUTE MYELOID LEUKEMIA, AML, RUNX1, RUNT DOMAIN, CHLORIDE BINDING, TRANSCRIPTION FACTOR, IG FOLD, TRANSCRIPTION-DNA complex ;; TRANSCRIPTION/DNA
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier25.37
rg_electron24.88
i013754200.00
molecular_weight27551.0 kDa
excluded_volume34139 ų
envelope_volume43964 ų
shell_volume15740 ų
envelope_diameter83.2
shell_rg30.19
envelope_rg24.64
shape_rg24.85
total_rg25.65
total_atoms1915
n_residues243
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax81.1
rg_real25.57
rg_real_error0.57
i0_real1.3750e+07
i0_real_error1.8030e+05
rg_reciprocal25.51
i0_reciprocal13750000.0000
total_estimate0.8304
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary20.6
skewness0.404
kurtosis-0.734
angular_range— – 0.3150 −1
current_alpha0.0000
highest_alpha2495000.0000
n_real_points64
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.758; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.543; Smooth: 0.975

4. Crystallography & Experiment

5. Entities & Polymer Info (3)

6. Citations (1)

7. Files & Curves (10)