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1efe

AN ACTIVE MINI-PROINSULIN, M2PI

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

MINI-PROINSULIN

Homo sapiens

UniProt P01308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1efe 1sju 1t0c 2jzq 2kqp 2lwz 4efx 4efx 4efx 4efx 5wbt 8pi6

16 assemblies; showing the first 12

Homodimer
1a7f 1ben 1ben 1guj 1guj 1hiq 1his 1hit 1hls 1hui 1iog 1ioh

155 assemblies; showing the first 12

Homotetramer
1b9e 1b9e 1fub 1lph 1lph 1trz 1trz 1tyl 1tyl 1tym 1tym 1xda

69 assemblies; showing the first 12

Other homooligomers
1ai0 1aiy 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben

244 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2g54 2g54 2g56 2g56 2wby 2wby 2wc0 2wc0 3utq 3uts 3uts 3utt

100 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name INS_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–30； UniProt 25–54 Author chain A； PDBConstruct 40–60； UniProt 90–110

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1efe
Deposition date deposition_date2000-02-08
Structure title titleAN ACTIVE MINI-PROINSULIN, M2PI
Keywords keywordsLINKER, INSULIN, PROINSULIN, HORMONE-GROWTH FACTOR COMPLEX; HORMONE/GROWTH FACTOR
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1efe__assembly_1__model_19

Assembly 1 · Model 19 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1efe__assembly_1__model_19 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1efe__assembly_1__model_19 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）13.47 Å
Rg (electron density)12.29 Å
Total Rg13.49 Å
Atom count947
Residues60
Excluded volume8583 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1efe__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 1efe__assembly_1__model_2 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 1efe__assembly_1__model_3 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 1efe__assembly_1__model_4 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 1efe__assembly_1__model_5 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 1efe__assembly_1__model_6 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 1efe__assembly_1__model_7 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 1efe__assembly_1__model_8 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 1efe__assembly_1__model_9 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 1efe__assembly_1__model_10 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 1efe__assembly_1__model_11 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 1efe__assembly_1__model_12 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 1efe__assembly_1__model_13 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 1efe__assembly_1__model_14 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 1efe__assembly_1__model_15 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 1efe__assembly_1__model_16 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 1efe__assembly_1__model_17 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 1efe__assembly_1__model_18 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 1efe__assembly_1__model_19 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 1efe__assembly_1__model_20 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1efea_
Class classg — Small proteins
Fold Fold foldg.1 — Insulin-like
Superfamily Superfamily superfamilyg.1.1 — Insulin-like
Family Family familyg.1.1.1 — Insulin-like

CATH v4.4 (1 domains)

Domain ID domain_id1efeA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology100 — Insulin-like, subunit E
Homologous superfamily homologous superfamily10 — Insulin-like
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7. Citations (2)