SAXSdb — 1xda

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1. Protein Identity and Related Structures Protein Identity & Related Structures

FATTY ACID ACYLATED INSULIN

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 2	PHENOL × 1 ZINC ION × 1 CHLORIDE ION × 1 MYRISTIC ACID × 1 water × 2	Consistent with protein count
10	Protein homooligomer	Homooligomer	Protein 6	PHENOL × 3 ZINC ION × 3 CHLORIDE ION × 3 MYRISTIC ACID × 3 water × 6	Consistent with protein count
11	Protein homooligomer	Homooligomer	Protein 4	PHENOL × 2 ZINC ION × 2 CHLORIDE ION × 2 MYRISTIC ACID × 2 water × 4	Consistent with protein count
12	Protein homooligomer	Homooligomer	Protein 4	PHENOL × 2 ZINC ION × 2 CHLORIDE ION × 2 MYRISTIC ACID × 2 water × 4	Consistent with protein count
2	Protein homooligomer	Homooligomer	Protein 2	PHENOL × 1 ZINC ION × 1 CHLORIDE ION × 1 MYRISTIC ACID × 1 water × 2	Consistent with protein count
3	Protein homooligomer	Homooligomer	Protein 2	PHENOL × 1 ZINC ION × 1 CHLORIDE ION × 1 MYRISTIC ACID × 1 water × 2	Consistent with protein count
4	Protein homooligomer	Homooligomer	Protein 2	PHENOL × 1 ZINC ION × 1 CHLORIDE ION × 1 MYRISTIC ACID × 1 water × 2	Consistent with protein count
5	Protein homooligomer	Homooligomer	Protein 12	PHENOL × 6 ZINC ION × 6 CHLORIDE ION × 6 MYRISTIC ACID × 6 water × 12	Consistent with protein count
6	Protein homooligomer	Homooligomer	Protein 12	PHENOL × 6 ZINC ION × 6 CHLORIDE ION × 6 MYRISTIC ACID × 6 water × 12	Consistent with protein count
7	Protein homooligomer	Homooligomer	Protein 6	PHENOL × 3 ZINC ION × 3 CHLORIDE ION × 3 MYRISTIC ACID × 3 water × 6	Consistent with protein count
8	Protein homooligomer	Homooligomer	Protein 6	PHENOL × 3 ZINC ION × 3 CHLORIDE ION × 3 MYRISTIC ACID × 3 water × 6	Consistent with protein count
9	Protein homooligomer	Homooligomer	Protein 6	PHENOL × 3 ZINC ION × 3 CHLORIDE ION × 3 MYRISTIC ACID × 3 water × 6	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	INS_HUMAN
Isoform	—
PDB entities	1, 2
Chains and sequence ranges	Author chain A； PDBConstruct 1–21； UniProt 90–110 Author chain C； PDBConstruct 1–21； UniProt 90–110 Author chain E； PDBConstruct 1–21； UniProt 90–110 Author chain G； PDBConstruct 1–21； UniProt 90–110 Author chain B； PDBConstruct 1–29； UniProt 25–53 Author chain D； PDBConstruct 1–29； UniProt 25–53 Author chain F； PDBConstruct 1–29； UniProt 25–53 Author chain H； PDBConstruct 1–29； UniProt 25–53

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1xda
Deposition date deposition_date	1996-12-18
Structure title title	STRUCTURE OF INSULIN
Keywords keywords	HORMONE, METABOLIC ROLE, CHEMICAL ACTIVITY, INSULIN ALBUMIN, FATTY ACID, GLUCOSE METABOLISM, DIABETES; HORMONE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1xda__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1xda__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1xda__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	11.89 Å
Rg (electron density)	10.80 Å
Total Rg	12.18 Å
Atom count	422
Residues	50
Excluded volume	7658 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1xda__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1xda__assembly_2__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`1xda__assembly_3__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`1xda__assembly_4__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	1	`1xda__assembly_5__model_1`	dodecameric （12）	Success	4.1.3-1-20251215 (887e7ef)	View Download
6	1	`1xda__assembly_6__model_1`	dodecameric （12）	Success	4.1.3-1-20251215 (887e7ef)	View Download
7	1	`1xda__assembly_7__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download
8	1	`1xda__assembly_8__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download
9	1	`1xda__assembly_9__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download
10	1	`1xda__assembly_10__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download
11	1	`1xda__assembly_11__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download
12	1	`1xda__assembly_12__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Description description	FATTY ACID ACYLATED INSULIN
Molecular weight formula_weight	2383.7 kDa
Source method src_method	man
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,C,E,G
Atom count atom_count	1860

GIVEQCCTSICSLYQLENYCN

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Saccharomyces cerevisiae

Entity 2 Entity 2 polymer

Description description	FATTY ACID ACYLATED INSULIN
Molecular weight formula_weight	3332.8 kDa
Source method src_method	man
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,D,F,H

FVNQHLCGSHLVEALYLVCGERGFFYTPK

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Saccharomyces cerevisiae

Entity 3 Entity 3 non-polymer

Description description	PHENOL
Molecular weight formula_weight	94.1 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 4 Entity 4 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 5 Entity 5 non-polymer

Description description	CHLORIDE ION
Molecular weight formula_weight	35.5 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 6 Entity 6 non-polymer

Description description	MYRISTIC ACID
Molecular weight formula_weight	228.4 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 7 Entity 7 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	154

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

Domain ID domain_id	d1xda.1
Class class	g — Small proteins
Fold Fold fold	g.1 — Insulin-like
Superfamily Superfamily superfamily	g.1.1 — Insulin-like
Family Family family	g.1.1.1 — Insulin-like

Domain ID domain_id	d1xda.2
Class class	g — Small proteins
Fold Fold fold	g.1 — Insulin-like
Superfamily Superfamily superfamily	g.1.1 — Insulin-like
Family Family family	g.1.1.1 — Insulin-like

Domain ID domain_id	d1xda.3
Class class	g — Small proteins
Fold Fold fold	g.1 — Insulin-like
Superfamily Superfamily superfamily	g.1.1 — Insulin-like
Family Family family	g.1.1.1 — Insulin-like

Domain ID domain_id	d1xda.4
Class class	g — Small proteins
Fold Fold fold	g.1 — Insulin-like
Superfamily Superfamily superfamily	g.1.1 — Insulin-like
Family Family family	g.1.1.1 — Insulin-like

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Unit-cell length a length_a	78.752 Å
Unit-cell length b length_b	78.752 Å
Unit-cell length c length_c	79.199 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	36

Space group space_group	H 3
Space-group number int_tables_number	146
Crystal system crystal_system	—

Resolution resolution	1.800 Å
Low-resolution limit resolution_low	15.000 Å
R factor r_factor	—
R_work r_work	0.1740
R_free r_free	—

STRUCTURE OF INSULIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

FATTY ACID ACYLATED INSULIN

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1xda__assembly_1__model_1

1xda__assembly_1__model_1 | I(q)

1xda__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

Entity 7 Entity 7 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

7. Citations (3)

STRUCTURE OF INSULIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

FATTY ACID ACYLATED INSULIN

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1xda__assembly_1__model_1

1xda__assembly_1__model_1 | I(q)

1xda__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

Entity 7 Entity 7 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

7. Citations (3)