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9pvo

Novel site 1 interaction of the IR/Ins-AC-S2 complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Isoform Long of Insulin receptor

Homo sapiens

UniProt P06213

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Insulin chain A × 1 Insulin chain B × 1 （P01308） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1i44 1irk 1p14 2mfr 3ekk 3ekn 3eta 3eta 4ibm 4ibm 5e1s 5hhw

13 assemblies; showing the first 12

Homodimer
3eta 4xlv 8u4b

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1gag 1gag 1ir3 1rqq 2auh 2b4s 2hr7 2z8c 3bu3 3bu5 3bu6 3w11

84 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name INSR_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–929； UniProt 28–956 Author chain B； PDBConstruct 1–929； UniProt 28–956

Insulin chain B

OrganismNot specified

UniProt P01308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Isoform Long of Insulin receptor × 2 （P06213） Insulin chain A × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1efe 1sju 1t0c 2jzq 2kqp 2lwz 4efx 4efx 4efx 4efx 5wbt 8pi6

16 assemblies; showing the first 12

Homodimer
1a7f 1ben 1ben 1guj 1guj 1hiq 1his 1hit 1hls 1hui 1iog 1ioh

155 assemblies; showing the first 12

Homotetramer
1b9e 1b9e 1fub 1lph 1lph 1trz 1trz 1tyl 1tyl 1tym 1tym 1xda

69 assemblies; showing the first 12

Other homooligomers
1ai0 1aiy 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben 1ben

244 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2g54 2g54 2g56 2g56 2wby 2wby 2wc0 2wc0 3utq 3uts 3uts 3utt

100 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name INS_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain R； PDBConstruct 1–29； UniProt 25–53

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9pvo
Deposition date deposition_date2025-08-03
Structure title titleNovel site 1 interaction of the IR/Ins-AC-S2 complex
Keywords keywordsAntagonism, receptor tyrosine kinase, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9pvo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9pvo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9pvo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）37.29 Å
Rg (electron density)36.53 Å
Total Rg37.00 Å
Atom count12697
Residues801
Excluded volume114430 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9pvo__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)