SAXSdb — 9puw

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1. Structure Basics

entry_id	9puw
deposition_date	2025-07-31
title	Insulin Receptor bound to Ins-AC-S2
keywords	Antagonist, receptor tyrosine kinase, MEMBRANE PROTEIN; MEMBRANE PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	53.82 Å
rg_electron	53.30 Å
i0	555177000.00
molecular_weight	194600.0 kDa
excluded_volume	242790 Å³
envelope_volume	405220 Å³
shell_volume	65238 Å³
envelope_diameter	169.6 Å
shell_rg	56.34 Å
envelope_rg	50.16 Å
shape_rg	53.28 Å
total_rg	53.48 Å
total_atoms	26929
n_residues	1697
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	166.2 Å
rg_real	53.73 Å
rg_real_error	1.67 Å
i0_real	5.5520e+08
i0_real_error	1.0650e+07
rg_reciprocal	53.87 Å
i0_reciprocal	555300000.0000
total_estimate	0.8622
solution_quality	GOOD a GOOD solution
n_peaks	1
r_peak_primary	68.8 Å
skewness	0.070
kurtosis	-0.768
angular_range	— – 0.1450 Å⁻¹
current_alpha	0.0000
highest_alpha	19800000.0000
n_real_points	30
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.982; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.998; Smooth: 0.261

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	Isoform Long of Insulin receptor
formula_weight	109477.6 kDa
ec_number	2.7.10.1
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	A,B,M,N
atom_count	26929

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKSSGPSGSHHHHHHGSDYKDDDDKDYKDDDDK

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	Ins-AC-S2 chain A
formula_weight	5520.0 kDa
src_method	syn
entity_count	2

Polymer

type	polypeptide(L)
strand_id	C,Q

GIVEQCCTSICSLYQLENYCGGSLPETGGGSLEEEWAQIQSEVWGRGCPSY

Entity 3 polymer

description	Insulin chain B
formula_weight	3332.8 kDa
src_method	syn
entity_count	2

Polymer

type	polypeptide(L)
strand_id	P,R

FVNQHLCGSHLVEALYLVCGERGFFYTPK

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6. Citations (1)

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resolution	3.64 Å
resolution_method	—
num_particles	314550

fit	/app/data/saxs_computation/pu/9puw/9puw.fit
pddf	/app/data/pr_computation/pu/9puw/9puw.pr.out
profile	/app/data/saxs_computation/pu/9puw/9puw.dat

Insulin Receptor bound to Ins-AC-S2

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

EM 3D

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Entity 3 polymer

Polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)