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9r4c

Spitrobot-2 advances time-resolvedcryo-trapping crystallography to under 25 ms: Human insulin, pH 4.5 (500 ms soaking)

Method: X-RAY DIFFRACTION Dmax: 38.0 Å Quality: REASONABLE

SAXS Profile

SAXS profile for 9r4c

P(r) Distribution

P(r) distribution for 9r4c

1. Structure Basics

entry_id9r4c
deposition_date2025-05-07
last_revision2025-12-03
titleSpitrobot-2 advances time-resolvedcryo-trapping crystallography to under 25 ms: Human insulin, pH 4.5 (500 ms soaking)
keywordsHuman insulin, pH-jump, HORMONE; HORMONE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier11.45
rg_electron9.99
i0891407.00
molecular_weight5908.0 kDa
excluded_volume7266 ų
envelope_volume7855 ų
shell_volume7014 ų
envelope_diameter35.4
shell_rg15.15
envelope_rg10.36
shape_rg9.99
total_rg11.44
total_atoms410
n_residues51
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax38.0
rg_real11.39
rg_real_error0.26
i0_real8.9140e+05
i0_real_error9.8760e+03
rg_reciprocal11.39
i0_reciprocal891400.0000
total_estimate0.7051
solution_quality REASONABLE a REASONABLE solution
n_peaks2
r_peak_primary14.9
skewness0.152
kurtosis-0.246
angular_range— – 0.5000 −1
current_alpha0.0000
highest_alpha91240.0000
n_real_points80
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.808; Stabil: 1.000; Sysdev: 0.256; Positv: 1.000; Valcen: 1.000; Smooth: 0.970

4. Crystallography & Experiment

5. Entities & Polymer Info (4)

6. Citations (1)

7. Files & Curves (10)