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1jt0

Crystal structure of a cooperative QacR-DNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

;HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION ;

Staphylococcus aureus

UniProt P0A0N4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 4 DNA 2 QACA operator × 2 SULFATE ION × 5 water × 6 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1jt6 1jt6 1jtx 1jtx 1jty 1jty 1jum 1jum 1jup 1jup 1jus 1jus

26 assemblies; showing the first 12

Homotetramer
1qvu

1 assemblies

Other homooligomers
2gby 2gby

2 assemblies

Heteromeric or nucleic-acid complex
1jt0

1 assemblies

View Construct and Data Evidence
UniProt name QACR_STAAU
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A； PDBConstruct 1–188； UniProt 1–188 Author chain B； PDBConstruct 1–188； UniProt 1–188 Author chain C； PDBConstruct 1–188； UniProt 1–188 Author chain D； PDBConstruct 1–188； UniProt 1–188

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1jt0
Deposition date deposition_date2001-08-20
Structure title titleCrystal structure of a cooperative QacR-DNA complex
Keywords keywordsmultidrug binding protein, cooperative DNA binding, dimer of dimers, TRANSCRIPTION-DNA COMPLEX; TRANSCRIPTION/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1jt0__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1jt0__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1jt0__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）36.25 Å
Rg (electron density)36.48 Å
Total Rg36.72 Å
Atom count7406
Residues805
Excluded volume128710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1jt0__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 19 domains

SCOP 2.08 (11 domains)

Domain ID domain_idd1jt0a1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.1 — Homeodomain-like
Family Family familya.4.1.9 — Tetracyclin repressor-like, N-terminal domain
Domain ID domain_idd1jt0a2
Class classa — All alpha proteins
Fold Fold folda.121 — Tetracyclin repressor-like, C-terminal domain
Superfamily Superfamily superfamilya.121.1 — Tetracyclin repressor-like, C-terminal domain
Family Family familya.121.1.1 — Tetracyclin repressor-like, C-terminal domain
Domain ID domain_idd1jt0a3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1jt0b1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.1 — Homeodomain-like
Family Family familya.4.1.9 — Tetracyclin repressor-like, N-terminal domain
Domain ID domain_idd1jt0b2
Class classa — All alpha proteins
Fold Fold folda.121 — Tetracyclin repressor-like, C-terminal domain
Superfamily Superfamily superfamilya.121.1 — Tetracyclin repressor-like, C-terminal domain
Family Family familya.121.1.1 — Tetracyclin repressor-like, C-terminal domain
Domain ID domain_idd1jt0b3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1jt0c1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.1 — Homeodomain-like
Family Family familya.4.1.9 — Tetracyclin repressor-like, N-terminal domain
Domain ID domain_idd1jt0c2
Class classa — All alpha proteins
Fold Fold folda.121 — Tetracyclin repressor-like, C-terminal domain
Superfamily Superfamily superfamilya.121.1 — Tetracyclin repressor-like, C-terminal domain
Family Family familya.121.1.1 — Tetracyclin repressor-like, C-terminal domain
Domain ID domain_idd1jt0c3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1jt0d1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.1 — Homeodomain-like
Family Family familya.4.1.9 — Tetracyclin repressor-like, N-terminal domain
Domain ID domain_idd1jt0d2
Class classa — All alpha proteins
Fold Fold folda.121 — Tetracyclin repressor-like, C-terminal domain
Superfamily Superfamily superfamilya.121.1 — Tetracyclin repressor-like, C-terminal domain
Family Family familya.121.1.1 — Tetracyclin repressor-like, C-terminal domain

CATH v4.4 (8 domains)

Domain ID domain_id1jt0A01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily60 — Homeodomain-like
Domain ID domain_id1jt0A02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily10 — Tetracycline Repressor, domain 2
Domain ID domain_id1jt0B01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily60 — Homeodomain-like
Domain ID domain_id1jt0B02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily10 — Tetracycline Repressor, domain 2
Domain ID domain_id1jt0C01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily60 — Homeodomain-like
Domain ID domain_id1jt0C02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily10 — Tetracycline Repressor, domain 2
Domain ID domain_id1jt0D01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily60 — Homeodomain-like
Domain ID domain_id1jt0D02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology357 — Tetracycline Repressor; domain 2
Homologous superfamily homologous superfamily10 — Tetracycline Repressor, domain 2
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7. Citations (1)