2bbj

Crystal structure of the CorA Mg2+ transporter

Method: X-RAY DIFFRACTION

▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

divalent cation transport-related protein

Thermotoga maritima

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 5	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q9WZ31_THEMA
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 4–354； UniProt 1–351 Author chain B； PDBConstruct 4–354； UniProt 1–351 Author chain D； PDBConstruct 4–354； UniProt 1–351 Author chain E； PDBConstruct 4–354； UniProt 1–351 Author chain F； PDBConstruct 4–354； UniProt 1–351

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id	2bbj
Deposition date deposition_date	2005-10-17
Structure title title	Crystal structure of the CorA Mg2+ transporter
Keywords keywords	;transporter, membrane, mg, pentamer, Structural Genomics, Structural Genomics Consortium, SGC, Metal Transport-Membrane Protein COMPLEX ;; Metal Transport/Membrane Protein
Experimental Method method	X-RAY DIFFRACTION

▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2bbj__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2bbj__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2bbj__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	40.43 Å
Rg (electron density)	40.30 Å
Total Rg	40.64 Å
Atom count	13805
Residues	1670
Excluded volume	249980 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2bbj__assembly_1__model_1`	pentameric （5）	Success	4.1.3-1-20251215 (887e7ef)	View Download

▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (1)

▼

6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

Domain ID domain_id	d2bbja1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2bbja2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2bbjb1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2bbjb2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2bbjd1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2bbjd2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2bbje1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2bbje2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2bbjf1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2bbjf2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

CATH v4.4 (15 domains)

Domain ID domain_id	2bbjA01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2bbjA02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjA03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjB01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2bbjB02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjB03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjD01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2bbjD02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjD03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjE01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2bbjE02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjE03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjF01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2bbjF02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2bbjF03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

▶

Unit-cell length a length_a	136.979 Å
Unit-cell length b length_b	173.181 Å
Unit-cell length c length_c	134.179 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	20

Space group space_group	P 21 21 2
Space-group number int_tables_number	18
Crystal system crystal_system	—

Resolution resolution	3.900 Å
Low-resolution limit resolution_low	20.000 Å
R factor r_factor	0.3630
R_work r_work	0.3608
R_free r_free	0.4065

Description description	divalent cation transport-related protein
Molecular weight formula_weight	41780.4 kDa
Source method src_method	man
Copy count entity_count	5

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,D,E,F
Atom count atom_count	13805

Crystal structure of the CorA Mg2+ transporter

1. Protein Identity and Related Structures Protein Identity & Related Structures

divalent cation transport-related protein

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2bbj__assembly_1__model_1

2bbj__assembly_1__model_1 | I(q)

2bbj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

CATH v4.4 (15 domains)

7. Citations (1)

Source organism organism	Thermotoga maritima
NCBI taxonomy ID ncbi_taxonomy_id	2336
Host organism host_organism	Escherichia coli BL21

Crystal structure of the CorA Mg2+ transporter

1. Protein Identity and Related Structures Protein Identity & Related Structures

divalent cation transport-related protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2bbj__assembly_1__model_1

2bbj__assembly_1__model_1 | I(q)

2bbj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

CATH v4.4 (15 domains)

7. Citations (1)