2iub

Crystal structure of a divalent metal ion transporter CorA at 2.9 A resolution.

Method: X-RAY DIFFRACTION Dmax: 184.3 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 2iub

P(r) 距离分布 P(r) Distribution

P(r) distribution for 2iub
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id2iub
沉积日期 deposition_date2006-06-01
结构标题 titleCrystal structure of a divalent metal ion transporter CorA at 2.9 A resolution.
关键词 keywordsMEMBRANE PROTEIN, CORA, DIVALENT CATION, ION TRANSPORTER; MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier54.38
回转半径 Rg (电子) rg_electron54.52
零角强度 I(0) i01906170000.00
分子量 molecular_weight390680.0 kDa
排除体积 excluded_volume499240 ų
包络体积 envelope_volume691770 ų
水化壳体积 shell_volume105660 ų
包络直径 envelope_diameter191.0
壳层 Rg shell_rg56.87
包络 Rg envelope_rg53.59
形状 Rg shape_rg54.52
总 Rg total_rg54.60
总原子数 total_atoms27567
残基数 n_residues3353
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax184.3
Rg (实空间) rg_real54.40
Rg 误差 (实空间) rg_real_error1.47
I(0) (实空间) i0_real1.9060e+09
I(0) 误差 (实空间) i0_real_error3.3280e+07
Rg (倒空间) rg_reciprocal54.35
I(0) (倒空间) i0_reciprocal1906000000.0000
解质量估计 total_estimate0.8702
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary63.6
偏度 Skewness skewness0.352
峰度 Kurtosis kurtosis-0.361
角度范围 angular_range— – 0.1450 −1
当前正则化参数 α current_alpha0.0001
最高正则化参数 α highest_alpha126300000.0000
实空间数据点数 n_real_points30
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.839; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.996; Smooth: 0.795

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 50 domains

SCOP 2.08 (20 domains)

结构域编号 domain_idd2iuba1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iuba2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubb1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubb2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubc1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubc2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubd1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubd2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iube1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iube2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubf1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubf2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubg1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubg2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubh1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubh2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubi1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubi2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_idd2iubj1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.328 — CorA soluble domain-like
超家族 Superfamily superfamilyd.328.1 — CorA soluble domain-like
家族 Family familyd.328.1.1 — CorA soluble domain-like
结构域编号 domain_idd2iubj2
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.3 — Magnesium transport protein CorA, transmembrane region
家族 Family familyf.17.3.1 — Magnesium transport protein CorA, transmembrane region

CATH v4.4 (30 domains)

结构域编号 domain_id2iubA01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubA02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubA03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubB01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubB02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubB03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubC01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubC02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubC03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubD01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubD02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubD03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubE01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubE02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubE03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubF01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubF02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubF03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubG01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubG02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubG03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubH01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubH02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubH03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubI01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubI02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubI03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubJ01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology460 — Beta Polymerase; domain 2
同源超家族 H-superfamily homologous superfamily20 — CorA soluble domain-like
结构域编号 domain_id2iubJ02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region
结构域编号 domain_id2iubJ03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
同源超家族 H-superfamily homologous superfamily340 — Magnesium transport protein CorA, transmembrane region

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8. 文件与曲线 (10)