2hn2

Crystal structure of the CorA Mg2+ transporter homologue from T. maritima in complex with divalent cations

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Magnesium transport protein corA

Thermotoga maritima

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 5	CALCIUM ION × 13	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CORA_THEMA
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 4–354； UniProt 1–351 Author chain B； PDBConstruct 4–354； UniProt 1–351 Author chain C； PDBConstruct 4–354； UniProt 1–351 Author chain D； PDBConstruct 4–354； UniProt 1–351 Author chain E； PDBConstruct 4–354； UniProt 1–351

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2hn2
Deposition date deposition_date	2006-07-11
Structure title title	Crystal structure of the CorA Mg2+ transporter homologue from T. maritima in complex with divalent cations
Keywords keywords	integral membrane protein; metal transporter protein; divalent cations, METAL TRANSPORT; METAL TRANSPORT
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2hn2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2hn2__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2hn2__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	39.96 Å
Rg (electron density)	39.79 Å
Total Rg	40.21 Å
Atom count	13698
Residues	1655
Excluded volume	248600 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2hn2__assembly_1__model_1`	pentameric （5）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

Domain ID domain_id	d2hn2a1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2hn2a2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2hn2b1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2hn2b2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2hn2c1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2hn2c2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2hn2d1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2hn2d2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	d2hn2e1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.328 — CorA soluble domain-like
Superfamily Superfamily superfamily	d.328.1 — CorA soluble domain-like
Family Family family	d.328.1.1 — CorA soluble domain-like

Domain ID domain_id	d2hn2e2
Class class	f — Membrane and cell surface proteins and peptides
Fold Fold fold	f.17 — Transmembrane helix hairpin
Superfamily Superfamily superfamily	f.17.3 — Magnesium transport protein CorA, transmembrane region
Family Family family	f.17.3.1 — Magnesium transport protein CorA, transmembrane region

CATH v4.4 (15 domains)

Domain ID domain_id	2hn2A01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2hn2A02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2A03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2B01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2hn2B02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2B03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2C01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2hn2C02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2C03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2D01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2hn2D02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2D03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2E01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	460 — Beta Polymerase; domain 2
Homologous superfamily homologous superfamily	20 — CorA soluble domain-like

Domain ID domain_id	2hn2E02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

Domain ID domain_id	2hn2E03
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	58 — Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous superfamily homologous superfamily	340 — Magnesium transport protein CorA, transmembrane region

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Unit-cell length a length_a	214.246 Å
Unit-cell length b length_b	86.298 Å
Unit-cell length c length_c	181.527 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	112.23 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	20

Space group space_group	C 1 2 1
Space-group number int_tables_number	5
Crystal system crystal_system	—

Resolution resolution	3.700 Å
Low-resolution limit resolution_low	20.000 Å
R factor r_factor	0.2951
R_work r_work	0.2950
R_free r_free	0.3160

Description description	Magnesium transport protein corA
Molecular weight formula_weight	41780.4 kDa
Source method src_method	man
Copy count entity_count	5

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E
Atom count atom_count	13698

Crystal structure of the CorA Mg2+ transporter homologue from T. maritima in complex with divalent cations

1. Protein Identity and Related Structures Protein Identity & Related Structures

Magnesium transport protein corA

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2hn2__assembly_1__model_1

2hn2__assembly_1__model_1 | I(q)

2hn2__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

CATH v4.4 (15 domains)

7. Citations (1)

Source organism organism	Thermotoga maritima
NCBI taxonomy ID ncbi_taxonomy_id	2336
Host organism host_organism	Escherichia coli

Description description	CALCIUM ION
Molecular weight formula_weight	40.1 kDa
Source method src_method	syn
Copy count entity_count	13

Crystal structure of the CorA Mg2+ transporter homologue from T. maritima in complex with divalent cations

1. Protein Identity and Related Structures Protein Identity & Related Structures

Magnesium transport protein corA

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2hn2__assembly_1__model_1

2hn2__assembly_1__model_1 | I(q)

2hn2__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

6. Fold Classification (SCOP + CATH) 25 domains

SCOP 2.08 (10 domains)

CATH v4.4 (15 domains)

7. Citations (1)