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2nti

Crystal structure of PCNA123 heterotrimer.

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA polymerase sliding clamp B

Sulfolobus solfataricus

UniProt P57766

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp C × 1 （Q97Z84） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 24 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp C × 1 （Q97Z84） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 17 water × 3 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp C × 1 （Q97Z84） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 13 POTASSIUM ION × 1 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2hii 2hii 2hik 2hik 2hik 2io4 2io4 2io4 2ix2 2izo 2nti 2nti

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PCNA2_SULSO
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–249； UniProt 1–249 Author chain D； PDBConstruct 1–249； UniProt 1–249 Author chain G； PDBConstruct 1–249； UniProt 1–249

DNA polymerase sliding clamp C

Sulfolobus solfataricus

UniProt Q97Z84

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 24 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 17 water × 3 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp A × 1 （P57765） BROMIDE ION × 13 POTASSIUM ION × 1 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2hii 2hii 2hik 2hik 2hik 2io4 2io4 2io4 2ix2 2izo 2nti 2nti

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PCNA3_SULSO
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 2–246； UniProt 1–245 Author chain E； PDBConstruct 2–246； UniProt 1–245 Author chain H； PDBConstruct 2–246； UniProt 1–245

DNA polymerase sliding clamp A

Sulfolobus solfataricus

UniProt P57765

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp C × 1 （Q97Z84） BROMIDE ION × 24 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp C × 1 （Q97Z84） BROMIDE ION × 17 water × 3 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 DNA polymerase sliding clamp B × 1 （P57766） DNA polymerase sliding clamp C × 1 （Q97Z84） BROMIDE ION × 13 POTASSIUM ION × 1 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2ijx 2ijx 2ijx 2ijx

4 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2hii 2hii 2hik 2hik 2hik 2ix2 2nti 2nti 2nti 7rpo 7rpw 7rpx

12 assemblies

View Construct and Data Evidence
UniProt name PCNA1_SULSO
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–244； UniProt 1–244 Author chain F； PDBConstruct 1–244； UniProt 1–244 Author chain I； PDBConstruct 1–244； UniProt 1–244

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2nti
Deposition date deposition_date2006-11-07
Structure title titleCrystal structure of PCNA123 heterotrimer.
Keywords keywordsprotein-protein interaction, PCNA123 heterotrimer, PCNA12 heterodimer, DNA BINDING PROTEIN; DNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2nti__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2nti__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2nti__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）32.66 Å
Rg (electron density)31.47 Å
Total Rg32.24 Å
Atom count5817
Residues737
Excluded volume104860 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2nti__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 2nti__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 2nti__assembly_3__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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6. Fold Classification (SCOP + CATH) 21 domains

SCOP 2.08 (12 domains)

Domain ID domain_idd2ntib1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntib2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntic1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntic2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntie1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntie2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntif1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntif2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntih1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntih2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntii1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches
Domain ID domain_idd2ntii2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.131 — DNA clamp
Superfamily Superfamily superfamilyd.131.1 — DNA clamp
Family Family familyd.131.1.0 — automated matches

CATH v4.4 (9 domains)

Domain ID domain_id2ntiA01
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiB00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiC00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiD01
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiE00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiF00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiG01
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiH00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
Domain ID domain_id2ntiI00
Class class3 — Alpha Beta
Architecture architecture70 — Box
Topology topology10 — Proliferating Cell Nuclear Antigen
Homologous superfamily homologous superfamily10 —
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7. Citations (1)