HOMO SAPIENS
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | ACETATE ION × 2 water × 1 | Consistent with protein count |
| UniProt name | KLH12_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 2–301； UniProt 268–567 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2vpj |
| Deposition date deposition_date | 2008-02-29 |
| Structure title title | Crystal structure of the Kelch domain of human KLHL12 |
| Keywords keywords | ;ADAPTOR PROTEIN, WNT SIGNALING PATHWAY, PROTEIN-BINDING, UBIQUITIN DEGRADATION, UBL CONJUGATION PATHWAY, CUL3, KELCH REPEAT, PHOSPHOPROTEIN, WNT SIGNALLING, PROTEIN BINDING ;; PROTEIN BINDING |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 18.66 Å |
| Rg (electron density) | 17.45 Å |
| Total Rg | 18.34 Å |
| Atom count | 2192 |
| Residues | 289 |
| Excluded volume | 38621 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2vpja_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.68 — 6-bladed beta-propeller |
| Superfamily Superfamily superfamily | b.68.11 — Kelch motif |
| Family Family family | b.68.11.0 — automated matches |
| Domain ID domain_id | 2vpjA00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 120 — 6 Propeller |
| Topology topology | 10 — Neuraminidase |
| Homologous superfamily homologous superfamily | 80 — Kelch-type beta propeller |