SAXSdb — 4bws

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1. Protein Identity and Related Structures Protein Identity & Related Structures

THIOREDOXIN-LIKE PROTEIN 4A

HOMO SAPIENS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	POLYGLUTAMINE-BINDING PROTEIN 1 × 1 （O60828） CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 × 1 （O95400） water × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	POLYGLUTAMINE-BINDING PROTEIN 1 × 1 （O60828） CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 × 1 （O95400） water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TXN4A_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 9–142； UniProt 4–137 Author chain D； PDBConstruct 9–142； UniProt 4–137

POLYGLUTAMINE-BINDING PROTEIN 1

HOMO SAPIENS

UniProt O60828

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	THIOREDOXIN-LIKE PROTEIN 4A × 1 （P83876） CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 × 1 （O95400） water × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	THIOREDOXIN-LIKE PROTEIN 4A × 1 （P83876） CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 × 1 （O95400） water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PQBP1_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–37； UniProt 229–265 Author chain E； PDBConstruct 1–37； UniProt 229–265

CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2

HOMO SAPIENS

UniProt O95400

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	THIOREDOXIN-LIKE PROTEIN 4A × 1 （P83876） POLYGLUTAMINE-BINDING PROTEIN 1 × 1 （O60828） water × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	THIOREDOXIN-LIKE PROTEIN 4A × 1 （P83876） POLYGLUTAMINE-BINDING PROTEIN 1 × 1 （O60828） water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CD2B2_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 10–71； UniProt 280–341 Author chain F； PDBConstruct 10–71； UniProt 280–341

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4bws
Deposition date deposition_date	2013-07-04
Structure title title	Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.
Keywords keywords	TRANSCRIPTION, NEURODEGENERATIVE DISORDERS; TRANSCRIPTION
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4bws__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4bws__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

4bws__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	19.83 Å
Rg (electron density)	18.82 Å
Total Rg	19.58 Å
Atom count	1815
Residues	221
Excluded volume	32139 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`4bws__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`4bws__assembly_2__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Description description	THIOREDOXIN-LIKE PROTEIN 4A
Molecular weight formula_weight	16743.2 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,D
Atom count atom_count	3667

MAHHHHHHMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYS

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 2 Entity 2 polymer

Description description	POLYGLUTAMINE-BINDING PROTEIN 1
Molecular weight formula_weight	3876.2 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,E

TGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 3 Entity 3 polymer

Description description	CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2
Molecular weight formula_weight	8482.4 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,F

MAHHHHHHMDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 4 Entity 4 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	16

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6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

Domain ID domain_id	d4bwsa_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.47 — Thioredoxin fold
Superfamily Superfamily superfamily	c.47.1 — Thioredoxin-like
Family Family family	c.47.1.8 — spliceosomal protein U5-15Kd

Domain ID domain_id	d4bwsc1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.76 — GYF/BRK domain-like
Superfamily Superfamily superfamily	d.76.1 — GYF domain
Family Family family	d.76.1.1 — GYF domain

Domain ID domain_id	d4bwsc2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4bwsd_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.47 — Thioredoxin fold
Superfamily Superfamily superfamily	c.47.1 — Thioredoxin-like
Family Family family	c.47.1.8 — spliceosomal protein U5-15Kd

Domain ID domain_id	d4bwsf1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.76 — GYF/BRK domain-like
Superfamily Superfamily superfamily	d.76.1 — GYF domain
Family Family family	d.76.1.1 — GYF domain

Domain ID domain_id	d4bwsf2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

CATH v4.4 (4 domains)

Domain ID domain_id	4bwsA00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	30 — Glutaredoxin
Homologous superfamily homologous superfamily	10 — Glutaredoxin

Domain ID domain_id	4bwsC00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	40 — GYF domain

Domain ID domain_id	4bwsD00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	30 — Glutaredoxin
Homologous superfamily homologous superfamily	10 — Glutaredoxin

Domain ID domain_id	4bwsF00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	40 — GYF domain

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Unit-cell length a length_a	144.180 Å
Unit-cell length b length_b	40.470 Å
Unit-cell length c length_c	168.171 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	95.92 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	I 1 2 1
Space-group number int_tables_number	5
Crystal system crystal_system	—

Resolution resolution	2.500 Å
Low-resolution limit resolution_low	41.818 Å
R factor r_factor	0.2399
R_work r_work	0.2379
R_free r_free	0.2770

Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.

1. Protein Identity and Related Structures Protein Identity & Related Structures

THIOREDOXIN-LIKE PROTEIN 4A

State in the Current Structure

Other States of the Same Protein in the Database

POLYGLUTAMINE-BINDING PROTEIN 1

State in the Current Structure

Other States of the Same Protein in the Database

CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4bws__assembly_1__model_1

4bws__assembly_1__model_1 | I(q)

4bws__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 water

6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

CATH v4.4 (4 domains)

7. Citations (1)

Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.

1. Protein Identity and Related Structures Protein Identity & Related Structures

THIOREDOXIN-LIKE PROTEIN 4A

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

POLYGLUTAMINE-BINDING PROTEIN 1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4bws__assembly_1__model_1

4bws__assembly_1__model_1 | I(q)

4bws__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 water

6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

CATH v4.4 (4 domains)

7. Citations (1)