← Back to search
5w7v

CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

TAR DNA-binding protein 43

OrganismNot specified

UniProt Q13148

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 270 No other associated polymer Consistent with protein count
2 Protein homooligomer Homooligomer Protein 9 No other associated polymer Consistent with protein count
3 Protein homooligomer Homooligomer Protein 9 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1wf0 2cqg 2n2c 2n3x 2n4g 2n4h 2n4p 5mrg 5x4f 6t4b 6t4b 6t4b

15 assemblies; showing the first 12

Homodimer
6b1g

1 assemblies

Homotetramer
7py2

1 assemblies

Other homooligomers
5w50 5w52 5w7v 5w7v 5w7v 5whn 5whp 5wia 5wiq 5wkb 5wkd 6cfh

23 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
4bs2 4iuf 4y00 4y00 4y00 4y00 4y0f 4y0f 6n3a 7n9h 9fof 9for

12 assemblies

View Construct and Data Evidence
UniProt name TADBP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 0； PDBConstruct 1–11； UniProt 247–257 Author chain 1； PDBConstruct 1–11； UniProt 247–257 Author chain 2； PDBConstruct 1–11； UniProt 247–257 Author chain 3； PDBConstruct 1–11； UniProt 247–257 Author chain 4； PDBConstruct 1–11； UniProt 247–257 Author chain 5； PDBConstruct 1–11； UniProt 247–257 Author chain 6； PDBConstruct 1–11； UniProt 247–257 Author chain 7； PDBConstruct 1–11； UniProt 247–257 Author chain 8； PDBConstruct 1–11； UniProt 247–257

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id5w7v
Deposition date deposition_date2017-06-20
Structure title titleCryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
Keywords keywordsAmyloid, steric zipper, PROTEIN FIBRIL; PROTEIN FIBRIL
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5w7v__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5w7v__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5w7v__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）44.16 Å
Rg (electron density)43.55 Å
Total Rg44.05 Å
Atom count20430
Residues2640
Excluded volume385710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5w7v__assembly_1__model_1 270-meric （270） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 5w7v__assembly_2__model_1 nonameric （9） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 5w7v__assembly_3__model_1 nonameric （9） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (1)

▶

7. Citations (1)