5x5p

Human serum transferrin bound to ruthenium NTA

Method: X-RAY DIFFRACTION D_max: 91.4 Å Quality: EXCELLENT

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Serotransferrin

物种未注明

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白单体单体蛋白 × 1 PDB 声明：monomeric（1）与蛋白拷贝数一致	链 A； UniProt 20–698	未记录	MLI MALONATE ION × 1 FE FE (III) ION × 1 RU RUTHENIUM ION × 4 NTA NITRILOTRIACETIC ACID × 2 NA SODIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件：VAPOR DIFFUSION, SITTING DROP；pH 6.6；298 K；PIPES-Na 100mM pH 6.6, disodium malonate 8mM, PEG 3350 18%, glycerol 17%	分辨率 2.70 Å R-free 0.219

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB	相对当前条目 5X5P	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
1A8E HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE 提交 1998-03-24	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 22–350（329 aa）片段：N-TERMINAL LOBE	未记录	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 5.75；277 K；PROTEIN WAS CRYSTALLIZED FROM 26% PEG 4000. BUFFER WAS 40MM NA CACODYLATE, PH 5.75, WITH 20MM NA BICARBONATE. CRYSTALS GROWN AT 4 DEGREES C USING THE HANGING DROP METHOD., vapor diffusion - hanging drop, temperature 277K	分辨率 1.60 Å
1A8F HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE 提交 1998-03-25	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 22–350（329 aa）片段：N-TERMINAL LOBE	未记录	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.1；PROTEIN WAS CRYSTALLIZED FROM 40% (V/V) ETHANOL WITH 50MM POTASSIUM CACODYLATE, PH 6.1. GROWN IN SITTING DROPS AT 277 K. RESERVOIRS CONTAINED 40% (V/V) ETHANOL, 50MM POTASSIUM CACODYLATE, PH 5.8 - 6.3. PRIOR TO CRYSTALLIZATION, THE PROTEIN WAS DIALYSED AGAINST SODIUM BICARBONATE, PH 8.1, vapor diffusion - sitting drop	分辨率 1.80 Å R-free 0.250
1B3E HUMAN SERUM TRANSFERRIN, N-TERMINAL LOBE, EXPRESSED IN PICHIA PASTORIS 提交 1998-12-09	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 23–352（330 aa）片段：N-TERMINAL LOBE	未记录	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.25；277 K；PROTEIN WAS CRYSTALLIZED FROM 40% (V/V) ETHANOL WITH 50MM SODIUM CACODYLATE, PH 6.25. GROWN IN SITTING DROPS AT 277 K. RESERVOIRS CONTAINED 40% (V/V) ETHANOL, 50MM SODIUM CACODYLATE, PH 5.8 - 6.3. PRIOR TO CRYSTALLIZATION, THE PROTEIN WAS DIALYSED AGAINST SODIUM BICARBONATE, PH 8.1, VAPOR DIFFUSION, SITTING DROP, temperature 277.0K	分辨率 2.50 Å R-free 0.255
1BP5 HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM 提交 1998-08-12	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 pH 5.3；PROTEIN WAS CRYSTALLIZED FROM 35% MPD. BUFFER WAS 50MM POTASSIUM ACETATE, PH 5.3, WITH 50MM KCL, AND 20MM NA BICARBONATE CRYSTALS GROWN AT 4 DEGREES C USING THE SITTING DROP METHOD.	分辨率 2.20 Å R-free 0.292
1BP5 HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM 提交 1998-08-12	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 pH 5.3；PROTEIN WAS CRYSTALLIZED FROM 35% MPD. BUFFER WAS 50MM POTASSIUM ACETATE, PH 5.3, WITH 50MM KCL, AND 20MM NA BICARBONATE CRYSTALS GROWN AT 4 DEGREES C USING THE SITTING DROP METHOD.	分辨率 2.20 Å R-free 0.292
1BP5 HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM 提交 1998-08-12	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 C 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 pH 5.3；PROTEIN WAS CRYSTALLIZED FROM 35% MPD. BUFFER WAS 50MM POTASSIUM ACETATE, PH 5.3, WITH 50MM KCL, AND 20MM NA BICARBONATE CRYSTALS GROWN AT 4 DEGREES C USING THE SITTING DROP METHOD.	分辨率 2.20 Å R-free 0.292
1BP5 HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM 提交 1998-08-12	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 D 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 pH 5.3；PROTEIN WAS CRYSTALLIZED FROM 35% MPD. BUFFER WAS 50MM POTASSIUM ACETATE, PH 5.3, WITH 50MM KCL, AND 20MM NA BICARBONATE CRYSTALS GROWN AT 4 DEGREES C USING THE SITTING DROP METHOD.	分辨率 2.20 Å R-free 0.292
1BTJ HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM, CRYSTAL FORM 2 提交 1998-09-01	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 5.3；PROTEIN DROP: 20 MG/ML PROTEIN, 20MM NAHCO3, 50 MM KCL. RESERVOIR: 50 MM POTASSIUM ACETATE, PH 5.3, 35% MPD., VAPOR DIFFUSION, SITTING DROP	分辨率 3.20 Å R-free 0.312
1BTJ HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM, CRYSTAL FORM 2 提交 1998-09-01	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–356（337 aa）片段：N-TERMINAL LOBE	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 5.3；PROTEIN DROP: 20 MG/ML PROTEIN, 20MM NAHCO3, 50 MM KCL. RESERVOIR: 50 MM POTASSIUM ACETATE, PH 5.3, 35% MPD., VAPOR DIFFUSION, SITTING DROP	分辨率 3.20 Å R-free 0.312
1D3K HUMAN SERUM TRANSFERRIN 提交 1999-09-29	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 22–350（329 aa）片段：N-TERMINAL LOBE	突变：K206Q	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 5.75；277 K；PEG 4000, sodium bicarbonate, sodium cacodylate, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K	分辨率 1.80 Å R-free 0.225
1D4N HUMAN SERUM TRANSFERRIN 提交 1999-10-04	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 22–350（329 aa）片段：N-TERMINAL LOBE	突变：H207E	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 5.75；277 K；PEG 4000, SODIUM BICARBONATE, SODIUM CACODYLATE, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 277K	分辨率 2.00 Å R-free 0.218
1DTG HUMAN TRANSFERRIN N-LOBE MUTANT H249E 提交 2000-01-12	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–353（334 aa）片段：N-TERMINAL HALF MOLECULE	突变：H249E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.1；277 K；50 mM cacodylate 40% ethanol, pH 6.1, VAPOR DIFFUSION, SITTING DROP, temperature 277K	分辨率 2.40 Å R-free 0.294
1FQE CRYSTAL STRUCTURES OF MUTANT (K206A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN 提交 2000-09-04	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–350（331 aa）片段：N-LOBE	突变：K206A	FE FE (III) ION × 1 CO3 CARBONATE ION × 1 K POTASSIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；20-25% PolyEthyleneGlycol 3350, 100mM Potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K	分辨率 1.80 Å R-free 0.237
1FQF CRYSTAL STRUCTURES OF MUTANT (K296A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN 提交 2000-09-04	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–350（331 aa）片段：N-LOBE	突变：K296A	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；18% PolyEthyleneGlycol 3350, 100mM Potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K	分辨率 2.10 Å R-free 0.295
1JQF Human Transferrin N-Lobe Mutant H249Q 提交 2001-08-06	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–353（334 aa）片段：N-TERMINUS (Residues 20-353)	突变：H249Q	CO3 CARBONATE ION × 1 FE FE (III) ION × 1 K POTASSIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Hanging drop. Protein solution 35 mg/ml protein in 0.1M ammonium bicarbonate pH 7.4. Reservoir solution 0.1M potassium acetate, pH 7.4, 20-25% PEG 3350. Equal volumes of protein and reservoir solutions mixed., VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 1.85 Å R-free 0.246
1N7W Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant 提交 2002-11-18	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–350（331 aa）片段：N-TERMINAL LOBE	突变：L66W	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.7；293 K；0.2M POTASSIUM ACETATE, 20% PEG 3350, pH 7.7, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 2.20 Å R-free 0.237
1N7X HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT 提交 2002-11-18	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–350（331 aa）片段：N-TERMINAL LOBE	突变：Y45E	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.7；293 K；0.2M POTASSIUM ACETATE, 20% PEG 3350, pH 7.7, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 2.10 Å R-free 0.243
1N84 HUMAN SERUM TRANSFERRIN, N-LOBE 提交 2002-11-19	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–350（331 aa）片段：N-TERMINAL LOBE	未记录	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.7；293 K；0.2M POTASSIUM ACETATE, 20% PEG 3350, pH 7.7, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 2.05 Å R-free 0.228
1OQG Crystal structure of the D63E mutant of the N-lobe human transferrin 提交 2003-03-09	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：N-lobe	突变：D63E	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；PEG 3350, potassium acetate, ammonium bicarbonate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 1.90 Å R-free 0.261
1OQH Crystal Structure of the R124A mutant of the N-lobe human transferrin 提交 2003-03-10	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：N-lobe	突变：R124A	CO3 CARBONATE ION × 1 FE FE (III) ION × 1 K POTASSIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；PEG 3350, potassium acetate, ammonium bicarbonate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.40 Å R-free 0.288
1RYO Human serum transferrin, N-lobe bound with oxalate 提交 2003-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–346（327 aa）片段：N-terminal lobe (residues 20-346)	未记录	OXL OXALATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.7；293 K；0.2M K-Acetate, 10mM KCl, 20% PEG 3350, pH 7.7, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 1.20 Å R-free 0.235
1SUV Structure of Human Transferrin Receptor-Transferrin Complex 提交 2004-03-26	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 6 PDB 声明：hexameric	链 C 22–350（329 aa）片段：repeat 1 链 D 22–350（329 aa）片段：repeat 1	未记录	CO3 CARBONATE ION × 4 FE FE (III) ION × 4	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.4	分辨率 7.50 Å
28MR X-ray structure of the adduct between human serum transferrin with Fe3+ bound at the C-lobe and diruthenium tetraacetate chloride 提交 2026-02-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 GOL GLYCEROL × 1 ACT ACETATE ION × 1 RU RUTHENIUM ION × 1 CL CHLORIDE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；15% (w/v) PEG 3350, 16% (v/v) glycerol, 8 mM disodium malonate, 150 mM Na-PIPES pH 6.5	分辨率 2.26 Å R-free 0.234
28MS X-ray structure of the adduct between human serum transferrin with Fe3+ bound at the C-lobe and dirhodium tetraacetate 提交 2026-02-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 ACT ACETATE ION × 3 PEG DI(HYDROXYETHYL)ETHER × 2 GOL GLYCEROL × 1 A1JZ3 Rhodium tetraacetate dihydrate × 9	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；15% (w/v) PEG 3350 16% (v/v) glycerol 8 mM disodium malonate 150 mM Na-PIPES pH 6.5	分辨率 2.37 Å R-free 0.244
2HAU Apo-Human Serum Transferrin (Non-Glycosylated) 提交 2006-06-13	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 23–698（676 aa）	突变：N413D,N611D 非标准单体：是（mmCIF未提供具体位点）	CIT CITRIC ACID × 1 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION；pH 6.5；293 K；15 mg/ml protein, 0.3 M ammonium citrate, 16-18% PEG 3350 , pH 6.5, VAPOR DIFFUSION, temperature 293K	分辨率 2.70 Å R-free 0.324
2HAU Apo-Human Serum Transferrin (Non-Glycosylated) 提交 2006-06-13	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 23–698（676 aa）	突变：N413D,N611D 非标准单体：是（mmCIF未提供具体位点）	CIT CITRIC ACID × 3 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION；pH 6.5；293 K；15 mg/ml protein, 0.3 M ammonium citrate, 16-18% PEG 3350 , pH 6.5, VAPOR DIFFUSION, temperature 293K	分辨率 2.70 Å R-free 0.324
2HAV Apo-Human Serum Transferrin (Glycosylated) 提交 2006-06-13	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 23–698（676 aa）	未记录	CIT CITRIC ACID × 3 GOL GLYCEROL × 3	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；294 K；30 mg/ml protein, 0.2 M ammonium citrate pH 7.0, 20% PEG-3350, 15% glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 294K	分辨率 2.70 Å R-free 0.293
2HAV Apo-Human Serum Transferrin (Glycosylated) 提交 2006-06-13	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 23–698（676 aa）	未记录	CIT CITRIC ACID × 4 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；294 K；30 mg/ml protein, 0.2 M ammonium citrate pH 7.0, 20% PEG-3350, 15% glycerol, VAPOR DIFFUSION, HANGING DROP, temperature 294K	分辨率 2.70 Å R-free 0.293
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 C 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 D 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 5 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 E 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 6 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 F 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 7 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 G 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 8 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 H 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O7U Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin 提交 2006-12-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 9 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 I 20–356（337 aa）片段：N-lobe	突变：K206E, K296E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；Protein: 35mg/ml, 0.1M ammonium bicarbonate. Well: 20% PEG 3350, 0.2 M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K	分辨率 2.80 Å R-free 0.259
2O84 Crystal structure of K206E mutant of N-lobe human transferrin 提交 2006-12-12	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 X 20–356（337 aa）片段：N-lobe	突变：K206E	FE FE (III) ION × 1 CO3 CARBONATE ION × 1 K POTASSIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；Protein: 35mg/ml, 0.1M ammonium bicrbonate. Well: 18% PEG3350, 0.2M potassium acetate, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K	分辨率 2.60 Å R-free 0.269
3FGS Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin 提交 2008-12-08	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–356（337 aa）片段：Peptidase S60 1 domain	突变：G65R, K206E	CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.7；293 K；200 mM potassium acetate buffer (pH 7.7) containing 10 mM KCl and 18% polyethylene glycol 3350. Concentration of the mutant was 17.5 mg/mL. Crystals appeared in approximately a week following micro-seeding with wild-type N-lobe, VAPOR DIFFUSION, HANGING DROP, temperature 293K	分辨率 1.80 Å R-free 0.246
3QYT Diferric bound human serum transferrin 提交 2011-03-03	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 2 CO3 CARBONATE ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 SO4 SULFATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.4；271 K；0.01M HEPES, 15% PEG3000, pH 7.4, vapor diffusion, sitting drop, temperature 271K	分辨率 2.80 Å R-free 0.275
3S9L Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 提交 2011-06-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 C 20–698（679 aa）片段：UNP residues 20-698	突变：N427D,Y440F, Y531F N625D	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 FE FE (III) ION × 2 CO3 CARBONATE ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 10% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.22 Å R-free 0.314
3S9L Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 提交 2011-06-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 D 20–698（679 aa）片段：UNP residues 20-698	突变：N427D,Y440F, Y531F N625D	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 FE FE (III) ION × 2 CO3 CARBONATE ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 10% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.22 Å R-free 0.314
3S9M Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 提交 2011-06-01	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 C 20–698（679 aa）片段：UNP residues 20-698	未记录	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 CO3 CARBONATE ION × 2 FE FE (III) ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 20% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.32 Å R-free 0.332
3S9M Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 提交 2011-06-01	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 D 20–698（679 aa）片段：UNP residues 20-698	未记录	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 CO3 CARBONATE ION × 2 FE FE (III) ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 20% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.32 Å R-free 0.332
3S9N Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature 提交 2011-06-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 C 20–698（679 aa）片段：UNP residues 20-698	突变：N427D, Y531F	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 FE FE (III) ION × 2 CO3 CARBONATE ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 10% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.25 Å R-free 0.289
3S9N Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature 提交 2011-06-01	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 D 20–698（679 aa）片段：UNP residues 20-698	突变：N427D, Y531F	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 FE FE (III) ION × 2 CO3 CARBONATE ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；5% PEG 3350, 0.2 M MgCl2, 10% 1,2-propanediol, pH Hepes 7.5, vapor diffusion, hanging drop, temperature 293K	分辨率 3.25 Å R-free 0.289
3SKP The structure of apo-human transferrin C-lobe with bound sulfate ions 提交 2011-06-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 358–698（341 aa）片段：iron binding protein	未记录	SO4 SULFATE ION × 8	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；294 K；0.2 M potassium sulfate, 2.2 M ammonium sulfate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K	分辨率 1.70 Å R-free 0.198
3SKP The structure of apo-human transferrin C-lobe with bound sulfate ions 提交 2011-06-22	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 4 PDB 声明：tetrameric	链 A 358–698（341 aa）片段：iron binding protein	未记录	SO4 SULFATE ION × 32	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；294 K；0.2 M potassium sulfate, 2.2 M ammonium sulfate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K	分辨率 1.70 Å R-free 0.198
3SKP The structure of apo-human transferrin C-lobe with bound sulfate ions 提交 2011-06-22	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 358–698（341 aa）片段：iron binding protein	未记录	SO4 SULFATE ION × 16	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；294 K；0.2 M potassium sulfate, 2.2 M ammonium sulfate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K	分辨率 1.70 Å R-free 0.198
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 5 P6G HEXAETHYLENE GLYCOL × 3	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 9 P6G HEXAETHYLENE GLYCOL × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 C 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 7 P6G HEXAETHYLENE GLYCOL × 3	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 D 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 9 P6G HEXAETHYLENE GLYCOL × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 5 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 E 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 9 P6G HEXAETHYLENE GLYCOL × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V83 The 2.1 angstrom crystal structure of diferric human transferrin 提交 2011-12-22	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 6 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2 SO4 SULFATE ION × 5 P6G HEXAETHYLENE GLYCOL × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；100mM HEPES, pH 7.5, 1.6 M ammonium sulfate, and 2% PEG 1000, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.10 Å R-free 0.230
3V89 The crystal structure of transferrin binding protein A (TbpA) from Neisseria meningitidis serogroup B in complex with the C-lobe of human transferrin 提交 2011-12-22	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 B 356–698（343 aa）片段：C-lobe (UNP residues 356-698)	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；21% PEG 1000, 100mM sodium acetate buffer (pH 4.8), 200mM NaCl, 0.1% LDAO and 3% heptane-1,2,3-triol, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 3.10 Å R-free 0.287
3V8X The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin 提交 2011-12-23	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 其他组合异源复合物；蛋白 × 2 PDB 声明：dimeric	链 B 1–698（698 aa）	未记录	C8E (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；20% Peg3350 and 200 mM BaBr2, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K	分辨率 2.60 Å R-free 0.267
3VE1 The 2.9 angstrom crystal structure of Transferrin binding protein B (TbpB) from serogroup B M982 Neisseria meningitidis in complex with human transferrin 提交 2012-01-06	聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 B 20–698（679 aa）	未记录	GOL GLYCEROL × 8 CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；0.1M sodium cacodylate pH 6.5, 14% PEG 3350, 0.1M sodium malonate, and 20% glycerol, vapor diffusion, hanging drop, temperature 293K	分辨率 2.96 Å R-free 0.249
3VE1 The 2.9 angstrom crystal structure of Transferrin binding protein B (TbpB) from serogroup B M982 Neisseria meningitidis in complex with human transferrin 提交 2012-01-06	聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 D 20–698（679 aa）	未记录	GOL GLYCEROL × 5 CO3 CARBONATE ION × 1 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；0.1M sodium cacodylate pH 6.5, 14% PEG 3350, 0.1M sodium malonate, and 20% glycerol, vapor diffusion, hanging drop, temperature 293K	分辨率 2.96 Å R-free 0.249
4H0W Bismuth bound human serum transferrin 提交 2012-09-10	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 CO3 CARBONATE ION × 2 BS3 Bismuth(III) ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 NTA NITRILOTRIACETIC ACID × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.4；271 K；0.01M HEPES, 15% PEG3000, PH 7.4, VAPOR DIFFUSION, SITTING DROP, temperature 271K	分辨率 2.40 Å R-free 0.256
4X1B Human serum transferrin with ferric ion bound at the C-lobe only 提交 2014-11-24	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；0.1M PIPES, 17% PEG3350, 18% Glycerol	分辨率 2.45 Å R-free 0.227
4X1D Ytterbium-bound human serum transferrin 提交 2014-11-24	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	YB YTTERBIUM (III) ION × 1 MLI MALONATE ION × 1 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；0.1M PIPES, 17% PEG3350, 18% Glycerol	分辨率 2.80 Å R-free 0.231
4X1D Ytterbium-bound human serum transferrin 提交 2014-11-24	配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–698（679 aa）	未记录	YB YTTERBIUM (III) ION × 1 MLI MALONATE ION × 1 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；0.1M PIPES, 17% PEG3350, 18% Glycerol	分辨率 2.80 Å R-free 0.231
5DYH Ti(IV) bound human serum transferrin 提交 2015-09-24	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 1–698（698 aa）	未记录	CIT CITRIC ACID × 6 4TI TITANIUM ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.4；296 K；10-13% PEG3350 100 mM Ammonium Citrate buffer	分辨率 2.68 Å R-free 0.237
5DYH Ti(IV) bound human serum transferrin 提交 2015-09-24	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 1–698（698 aa）	未记录	CIT CITRIC ACID × 5 4TI TITANIUM ION × 1 CO3 CARBONATE ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7.4；296 K；10-13% PEG3350 100 mM Ammonium Citrate buffer	分辨率 2.68 Å R-free 0.237
5H52 Structure of Titanium-bound human serum transferrin 提交 2016-11-04	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	MLI MALONATE ION × 1 4TI TITANIUM ION × 2 CIT CITRIC ACID × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；298 K；PIPES-Na 0.1M, PEG 3350 17%, disodium malonate 8mM, glycerol 18%	分辨率 3.00 Å R-free 0.224
5WTD Structure of human serum transferrin bound ruthenium at N-lobe 提交 2016-12-11	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 RU RUTHENIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION；pH 6.6；298 K；PIPES-Na 100 mM, disodium malonate 8 mM, PEG3350 17%, glycerol 18%	分辨率 2.50 Å R-free 0.214
5Y6K Human serum trnasferrin bound to a fluorescent probe 提交 2017-08-12	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	MLI MALONATE ION × 1 FE FE (III) ION × 2 8R6 (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.6；298 K；PIPES-Na 0.1M pH 6.6, disodium malonate 8mM, PEG 3350 17%, glycerol 18%	分辨率 2.86 Å R-free 0.235
6CTC Crystal structure of human transferrin bound to Triferic FPC iron pyrophosphate 提交 2018-03-22	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 2 CO3 CARBONATE ION × 1 POP PYROPHOSPHATE 2- × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.5；291 K；Apo human transferrin (ProSpec pro-325 purified by Q-sepharose) at 56 mg/mL (0.76 mM) against Morpheus screen condition D4 12.5% PEG 1000, 12.5% PEG3350, 12.5% MPD, 0.02 M each 1,6-hexanediol, 1-butanol, RS-1,2-propanediol, 2-propanol, 1,4-butanediol, 1,3-propanediol, 0.1 M MES/imidazole pH 6.5, crystal tracking ID 246352d4, unique puck ID suv0-5	分辨率 2.60 Å R-free 0.253
6D03 Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; one molecule of parasite ligand. 提交 2018-04-10	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 其他组合异源复合物；蛋白 × 5 PDB 声明：pentameric	链 C 1–698（698 aa）链 D 1–698（698 aa）	未记录	CA CALCIUM ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 FE FE (III) ION × 4 CO3 CARBONATE ION × 4	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.68 Å
6D04 Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 1. 提交 2018-04-10	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 其他组合异源复合物；蛋白 × 6 PDB 声明：hexameric	链 C 1–698（698 aa）链 D 1–698（698 aa）	未记录	CA CALCIUM ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 FE FE (III) ION × 4 CO3 CARBONATE ION × 4	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.74 Å
6D05 Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 2. 提交 2018-04-10	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 其他组合异源复合物；蛋白 × 6 PDB 声明：hexameric	链 C 1–698（698 aa）链 D 1–698（698 aa）	未记录	CA CALCIUM ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 FE FE (III) ION × 4 CO3 CARBONATE ION × 4	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.80 Å
6JAS Human serum transferrin with iron citrate bound 提交 2019-01-25	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 2 MLI MALONATE ION × 1 CIT CITRIC ACID × 1	X-RAY DIFFRACTION X-ray结晶条件 EVAPORATION；pH 6.6；298 K；PIPES-NaOH 0.1M pH 6.6, di-sodium malonate 8 mM, glycerol 18%, PEG3350 17%	分辨率 2.50 Å R-free 0.219
6SOY Trypanosoma brucei transferrin receptor in complex with human transferrin 提交 2019-08-30	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 C 22–698（677 aa）	未记录	FE FE (III) ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；291 K；12% (w/v) PEG 5000 MME, 12% 2-methyl-2,4-pentanediol, 0.1 M MES, pH 6.5	分辨率 2.75 Å R-free 0.233
6SOZ Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin 提交 2019-08-30	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 其他组合异源复合物；蛋白 × 3 PDB 声明：trimeric	链 C 22–698（677 aa）	未记录	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 FE FE (III) ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；291 K；12% (w/v) PEG 5000 MME, 12% 2-methyl-2,4-pentanediol, 0.1 M MES, pH 6.5	分辨率 3.42 Å R-free 0.241
7FFM Human serum transferrin with five osmium binding sites 提交 2021-07-23	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	4TI TITANIUM ION × 1 MLI MALONATE ION × 1 NTA NITRILOTRIACETIC ACID × 1 OS OSMIUM ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.6；298 K；PIPES-Na 100mM pH 6.5, di-sodium malonate 8mM, PEG3350 17%, glycerol 18%	分辨率 3.06 Å R-free 0.212
7FFU Osmium-bound human serum transferrin 提交 2021-07-23	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 OS OSMIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.6；298 K；PIPES-NaOH 0.1M pH 6.6, disodium malonate 8mM, glycerol 18%, PEG 3350 17%	分辨率 2.60 Å R-free 0.229
7Q1L Glycosilated Human Serum Apo-tranferrin 提交 2021-10-20	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 其他组合单体；蛋白 × 1 PDB 声明：monomeric	链 A 23–698（676 aa）	未记录	GOL GLYCEROL × 5 EDO 1,2-ETHANEDIOL × 1 MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；291.5 K；0.2 M Ammonium Citrate pH 7.0, 20% PEG 3350	分辨率 3.00 Å R-free 0.249
7Q1L Glycosilated Human Serum Apo-tranferrin 提交 2021-10-20	构建体不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 其他组合单体；蛋白 × 1 PDB 声明：monomeric	链 B 23–698（676 aa）	未记录	GOL GLYCEROL × 2 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；291.5 K；0.2 M Ammonium Citrate pH 7.0, 20% PEG 3350	分辨率 3.00 Å R-free 0.249
8BRC Crystal structure of the adduct between human serum transferrin and cisplatin 提交 2022-11-22	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLI MALONATE ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 PT PLATINUM (II) ION × 1 NH3 AMMONIA × 2	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；15% w/v PEG 3350, 16% v/v glycerol, 8 mM disodium malonate, and 150 mM Na-PIPES pH 6.5	分辨率 3.17 Å R-free 0.243
9CDQ Transferrin Binding Protein A in complex with transferrin (iron bound in N lobe only) 提交 2024-06-25	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 1 FE FE (III) ION × 1	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.8 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.76 Å
9CLM Transferrin Binding Protein A in complex with transferrin binding protein B and two molecules of transferrin 提交 2024-07-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 F 1–698（698 aa）链 G 1–698（698 aa）	未记录	BCT BICARBONATE ION × 3 FE FE (III) ION × 3	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 4.30 Å
9CLT Transferrin Binding Protein A in complex with transferrin binding protein B and transferrin (iron bound to N lobe only) 提交 2024-07-12	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 1 FE FE (III) ION × 1	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.60 Å
9CMG Transferrin Binding Protein A in complex with transferrin binding protein B and transferrin (iron bound in both lobes of Tf) 提交 2024-07-15	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.71 Å
9DC4 Transferrin Binding Protein A in complex with transferrin binding protein B, transferrin and globular domain of TonB 提交 2024-08-25	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 4 PDB 声明：tetrameric	链 F 1–696（696 aa）	未记录	BCT BICARBONATE ION × 1 FE FE (III) ION × 1	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.10 Å
9H49 Crystal structure of the adduct between human serum transferrin (apo-form) and cisplatin 提交 2024-10-17	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	CIT CITRIC ACID × 3 PT PLATINUM (II) ION × 2 NH3 AMMONIA × 4	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；20% w/v PEG 3350 and 200 mM ammonium citrate pH 7.0	分辨率 3.52 Å R-free 0.249
9H49 Crystal structure of the adduct between human serum transferrin (apo-form) and cisplatin 提交 2024-10-17	配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–698（679 aa）	未记录	CIT CITRIC ACID × 3 PT PLATINUM (II) ION × 2 NH3 AMMONIA × 4	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；20% w/v PEG 3350 and 200 mM ammonium citrate pH 7.0	分辨率 3.52 Å R-free 0.249
9H4V Crystal structure of the adduct formed upon reaction of aurothiomalate with human serum transferrin (apo-form) 提交 2024-10-21	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 20–698（679 aa）	未记录	CIT CITRIC ACID × 4 AU GOLD ION × 9	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；20% w/v PEG 3350 and 200 mM trisodium citrate	分辨率 3.02 Å R-free 0.296
9H4V Crystal structure of the adduct formed upon reaction of aurothiomalate with human serum transferrin (apo-form) 提交 2024-10-21	配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 20–698（679 aa）	未记录	CIT CITRIC ACID × 4 AU GOLD ION × 10 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；293 K；20% w/v PEG 3350 and 200 mM trisodium citrate	分辨率 3.02 Å R-free 0.296
9PA8 NmTbpB and Tf protein complex 提交 2025-06-25	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 2 FE FE (III) ION × 2	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.5 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 3.10 Å
9THO Crystal structure of the adduct formed upon reaction of [V(IV)O(acetylacetonate)2] with human serum transferrin with Fe(III) bound at the C-lobe only 提交 2025-12-03	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 AAA 20–698（679 aa）	未记录	BCT BICARBONATE ION × 11 GOL GLYCEROL × 2 FE FE (III) ION × 1 MLA MALONIC ACID × 1 A1JJT bis(oxidanyl)-oxidanylidene-(oxidanyl(oxidanylidene)vanadio)oxy-vanadium × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；293 K；15% (w/v) PEG 3350, 16% (v/v) glycerol, 8 mM disodium malonate, 150 mM Na-PIPES pH 6.5	分辨率 2.55 Å R-free 0.249
9THQ Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only 提交 2025-12-03	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 AAA 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLA MALONIC ACID × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 GOL GLYCEROL × 1 BCT BICARBONATE ION × 9	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；293 K；15% (w/v) PEG 3350, 16% (v/v) glycerol, 8 mM disodium malonate, 150 mM Na-PIPES pH 6.5	分辨率 2.44 Å R-free 0.231
9THR Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only (treated with DMSO) 提交 2025-12-03	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 AAA 20–698（679 aa）	未记录	FE FE (III) ION × 1 MLA MALONIC ACID × 1 GOL GLYCEROL × 1 BCT BICARBONATE ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；293 K；15% (w/v) PEG 3350, 16% (v/v) glycerol, 8 mM disodium malonate, 150 mM Na-PIPES pH 6.5	分辨率 3.20 Å R-free 0.249
9YZ4 Neisseria gonorrhoeae Transferrin Binding Protein A in complex with Transferrin Binding Protein B and transferrin (iron bound in N lobe only) 提交 2025-10-29	构建体不同聚集状态不同配体/离子不同实验方法不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 F 1–698（698 aa）	未记录	BCT BICARBONATE ION × 1 FE FE (III) ION × 1	ELECTRON MICROSCOPY cryo-EM缓冲液 pH 7.8 cryo-EM玻璃化条件冷冻剂 ETHANE	分辨率 4.26 Å

共 64 个其他 PDB 条目、94 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	TRFE_HUMAN
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–679； UniProt 20–698

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	5x5p
沉积日期 deposition_date	2017-02-17
结构标题 title	Human serum transferrin bound to ruthenium NTA
关键词 keywords	transferrin, ruthenium, NTA, METAL TRANSPORT; METAL TRANSPORT
实验方法 method	X-RAY DIFFRACTION

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3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	29.29 Å
回转半径 Rg (电子) rg_electron	28.29 Å
零角强度 I(0) i0	89365600.00
分子量 molecular_weight	71869.0 kDa
排除体积 excluded_volume	88702 Å³
包络体积 envelope_volume	109660 Å³
水化壳体积 shell_volume	32779 Å³
包络直径 envelope_diameter	95.0 Å
壳层 Rg shell_rg	35.16 Å
包络 Rg envelope_rg	28.08 Å
形状 Rg shape_rg	28.24 Å
总 Rg total_rg	29.09 Å
总原子数 total_atoms	5008
残基数 n_residues	649
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	91.4 Å
Rg (实空间) rg_real	29.26 Å
Rg 误差 (实空间) rg_real_error	0.79 Å
I(0) (实空间) i0_real	8.9370e+07
I(0) 误差 (实空间) i0_real_error	1.3320e+06
Rg (倒空间) rg_reciprocal	29.27 Å
I(0) (倒空间) i0_reciprocal	89370000.0000
解质量估计 total_estimate	0.9047
解质量评级 solution_quality	EXCELLENT a EXCELLENT solution
P(r) 峰数 n_peaks	1
主峰位置 r_peak_primary	32.2 Å
偏度 Skewness skewness	0.255
峰度 Kurtosis kurtosis	-0.534
角度范围 angular_range	— – 0.2700 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	16850000.0000
实空间数据点数 n_real_points	55
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.959; Stabil: 0.999; Sysdev: 1.000; Positv: 1.000; Valcen: 0.999; Smooth: 0.882

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5. 晶体学与实验 5. Crystallography & Experiment

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6. 实体与聚合物信息 Entities & Polymers (7)

实体 1 Entity 1 polymer

描述 description	Serotransferrin
分子量 formula_weight	75298.5 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A
原子数 atom_count	5017

VPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP

实体 2 Entity 2 non-polymer

描述 description	MALONATE ION
分子量 formula_weight	102.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 3 Entity 3 non-polymer

描述 description	FE (III) ION
分子量 formula_weight	55.8 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 4 Entity 4 non-polymer

描述 description	RUTHENIUM ION
分子量 formula_weight	101.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	4

实体 5 Entity 5 non-polymer

描述 description	NITRILOTRIACETIC ACID
分子量 formula_weight	191.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	2

实体 6 Entity 6 non-polymer

描述 description	SODIUM ION
分子量 formula_weight	23.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	1

实体 7 Entity 7 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	9

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7. 折叠分类 (SCOP + CATH) 6 domains

SCOP 2.08 (2 domains)

结构域编号 domain_id	d5x5pa1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.94 — Periplasmic binding protein-like II
超家族 Superfamily superfamily	c.94.1 — Periplasmic binding protein-like II
家族 Family family	c.94.1.0 — automated matches

结构域编号 domain_id	d5x5pa2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.94 — Periplasmic binding protein-like II
超家族 Superfamily superfamily	c.94.1 — Periplasmic binding protein-like II
家族 Family family	c.94.1.0 — automated matches

CATH v4.4 (4 domains)

结构域编号 domain_id	5x5pA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	190 — D-Maltodextrin-Binding Protein; domain 2
同源超家族 H-superfamily homologous superfamily	10 — Periplasmic binding protein-like II

结构域编号 domain_id	5x5pA02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	190 — D-Maltodextrin-Binding Protein; domain 2
同源超家族 H-superfamily homologous superfamily	10 — Periplasmic binding protein-like II

结构域编号 domain_id	5x5pA03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	190 — D-Maltodextrin-Binding Protein; domain 2
同源超家族 H-superfamily homologous superfamily	10 — Periplasmic binding protein-like II

结构域编号 domain_id	5x5pA04
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	190 — D-Maltodextrin-Binding Protein; domain 2
同源超家族 H-superfamily homologous superfamily	10 — Periplasmic binding protein-like II

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8. 引用文献 (1)

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晶胞边长 a length_a	136.748 Å
晶胞边长 b length_b	158.395 Å
晶胞边长 c length_c	106.610 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	8

空间群 space_group	C 2 2 21
空间群编号 int_tables_number	20
晶系 crystal_system	—

分辨率 resolution	2.700 Å
最低分辨率 resolution_low	49.255 Å
R 因子 r_factor	0.1708
R_work r_work	0.1682
R_free r_free	0.2189

fit	/app/data/saxs_computation/x5/5x5p/5x5p.fit
pddf	/app/data/pr_computation/x5/5x5p/5x5p.pr.out
profile	/app/data/saxs_computation/x5/5x5p/5x5p.dat