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6a9o

Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis

Method: X-RAY DIFFRACTION Dmax: 141.1 Å Quality: REASONABLE
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Superoxide dismutase [Cu-Zn]

Homo sapiens

UniProt P00441

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 1–154 Chain B； UniProt 1–154 Not recorded ZN ZINC ION × 2 DMS DIMETHYL SULFOXIDE × 1 GOL GLYCEROL × 2 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；293 K；1.5M Sodium Citrate, pH 6.0 Resolution 2.50 Å R-free 0.237
2 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 1–154 Chain D； UniProt 1–154 Not recorded ZN ZINC ION × 2 DMS DIMETHYL SULFOXIDE × 1 GOL GLYCEROL × 2 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；293 K；1.5M Sodium Citrate, pH 6.0 Resolution 2.50 Å R-free 0.237
3 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain E； UniProt 1–154 Chain F； UniProt 1–154 Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 6B3 2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；293 K；1.5M Sodium Citrate, pH 6.0 Resolution 2.50 Å R-free 0.237
4 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain G； UniProt 1–154 Chain H； UniProt 1–154 Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；293 K；1.5M Sodium Citrate, pH 6.0 Resolution 2.50 Å R-free 0.237
5 Protein homooligomer Homooligomer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain I； UniProt 1–154 Chain J； UniProt 1–154 Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；293 K；1.5M Sodium Citrate, pH 6.0 Resolution 2.50 Å R-free 0.237

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 6A9O Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1AZV FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN) Deposited 1997-11-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：G37R Mutation：G37R CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；20 MG/ML PROTEIN IN 10MM ACETATE PH 5.5 MIXED WITH PRECIPITATING SOLUTION OF 100 MM ACETATE PH 4.6, 2.0 M AMMONIUM SULFATE
Resolution 1.90 Å R-free 0.244
1BA9 THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES Deposited 1998-04-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–153（153 aa）
Mutation：C6A, F50E, G51E, C111S, E133Q ZN ZINC ION × 1 CU1 COPPER (I) ION × 1 SOLUTION NMR
NMR measurement conditions pH 5；298 K；Pressure 1
NMR sample composition H2O AND D2O
Resolution not provided
1DSW THE SOLUTION STRUCTURE OF A MONOMERIC, REDUCED FORM OF HUMAN COPPER, ZINC SUPEROXIDE DISMUTASE BEARING THE SAME CHARGE AS THE NATIVE PROTEIN Deposited 2000-01-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa） Fragment：;M4SOD IS A MONOMERIC VARIANT OF HUMAN SOD. THE MUTANT IS STUDIED IN THE REDUCED FORM, EACH MOLECULE CONTAINS A CU(I) AND A ZN(II) IONS. ;
Mutation：YES CU COPPER (II) ION × 1 ZN ZINC ION × 1 SOLUTION NMR
NMR measurement conditions pH 5；298 K；Pressure ATMOSPHERIC
NMR sample composition 2MM M4SOD FULLY ENRICHED IN 15N; 20MM PHOSPHATE BUFFER PH 5.0; 90% H2O, 10% D2O. THE PROTEIN WAS REDUCED WITH SODIUM ISOASCORBATE UNDER UNAEROBIC CONDITIONS.
Resolution not provided
1FUN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) Deposited 1998-07-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Mutation：C6A, C111S, K136E Mutation：C6A, C111S, K136E CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.85 Å
1FUN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) Deposited 1998-07-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–153（153 aa）
Chain G 1–153（153 aa）
Mutation：C6A, C111S, K136E Mutation：C6A, C111S, K136E CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.85 Å
1FUN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) Deposited 1998-07-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain H 1–153（153 aa）
Mutation：C6A, C111S, K136E Mutation：C6A, C111S, K136E CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.85 Å
1FUN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) Deposited 1998-07-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–153（153 aa）
Chain I 1–153（153 aa）
Mutation：C6A, C111S, K136E Mutation：C6A, C111S, K136E CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.85 Å
1FUN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) Deposited 1998-07-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain J 1–153（153 aa）
Mutation：C6A, C111S, K136E Mutation：C6A, C111S, K136E CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.85 Å
1HL4 The Structure of Apo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2M NH4CL, 20%PEG2000, 10% ETHYLENE GLYCOL, 0.1 M MES PH 5.6
Resolution 1.82 Å R-free 0.283
1HL4 The Structure of Apo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2M NH4CL, 20%PEG2000, 10% ETHYLENE GLYCOL, 0.1 M MES PH 5.6
Resolution 1.82 Å R-free 0.283
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain H 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 2–154（153 aa）
Chain I 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain J 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 2–154（153 aa）
Chain K 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain L 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 2–154（153 aa）
Chain M 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 7 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Chain N 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 8 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain O 2–154（153 aa）
Chain Q 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1HL5 The Structure of Holo Type Human Cu, Zn Superoxide Dismutase Deposited 2003-03-13 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 9 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain P 2–154（153 aa）
Chain S 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2 M CA ACETATE, 15% PEG 3350, 0.1 M TRIS PH 8.0
Resolution 1.80 Å R-free 0.222
1KMG The Solution Structure Of Monomeric Copper-free Superoxide Dismutase Deposited 2001-12-15 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–153（153 aa）
Mutation：C6A, F50E, G51E, C111S, E133Q ZN ZINC ION × 1 SOLUTION NMR
NMR measurement conditions pH 5；298 K；Ionic strength (raw mmCIF value) 20 mM phosphate；Pressure 1
NMR sample composition 2mM of 15N and 13C enriched superoxide dismutase | 20mM phosphate buffer, 10% D20
NMR sample composition 2mM of 15N and 13C enriched superoxide dismutase | 20mM phosphate buffer, 10% D20
NMR sample composition 2mM unlabelled superoxide dismutase | 20mM phosphate buffer, 10% D20
Resolution not provided
1L3N The Solution Structure of Reduced Dimeric Copper Zinc SOD: the Structural Effects of Dimerization Deposited 2002-02-28 Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SOLUTION NMR
NMR measurement conditions pH 5；296 K；Pressure 1
NMR measurement conditions pH 5；286 K；Pressure 1
NMR sample composition Cu(I),Zn(II) SOD 2mM enriched in 15N | 20mM phosphate buffer pH5.00 10% D2O, 8mM ascorbate reductant
NMR sample composition Cu(I),Zn(II) SOD 2mM enriched in 15N, 13C | 20mM phosphate buffer pH5.00 10% D2O, 8mM ascorbate reductant
NMR sample composition Cu(I),Zn(II) SOD 2mM enriched in 15N, 13C and 2H at 70% | 20mM phosphate buffer pH5.00 10% D2O, 8mM ascorbate reductant
NMR sample composition Cu(I),Zn(II) SOD 2mM enriched in 15N | 20mM phosphate buffer pH5.00 100% D2O, 8mM ascorbate reductant
Resolution not provided
1MFM MONOMERIC HUMAN SOD MUTANT F50E/G51E/E133Q AT ATOMIC RESOLUTION Deposited 1999-04-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–153（153 aa）
Mutation：C6A,F50E,G51E,C111S,E133Q ZN ZINC ION × 1 CU COPPER (II) ION × 1 CD CADMIUM ION × 9 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；PEG 6000 15%, CDCL2 200-400 MM, TRIS 100MM, PH=8, pH 8.0
Resolution 1.02 Å
1N18 Thermostable mutant of Human Superoxide Dismutase, C6A, C111S Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 0–153（154 aa）
Chain B 0–153（154 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；Ammonium Sulfate, NaCl, Tris, EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.250
1N18 Thermostable mutant of Human Superoxide Dismutase, C6A, C111S Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 0–153（154 aa）
Chain D 0–153（154 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；Ammonium Sulfate, NaCl, Tris, EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.250
1N18 Thermostable mutant of Human Superoxide Dismutase, C6A, C111S Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 0–153（154 aa）
Chain F 0–153（154 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；Ammonium Sulfate, NaCl, Tris, EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.250
1N18 Thermostable mutant of Human Superoxide Dismutase, C6A, C111S Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 0–153（154 aa）
Chain H 0–153（154 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；Ammonium Sulfate, NaCl, Tris, EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.250
1N18 Thermostable mutant of Human Superoxide Dismutase, C6A, C111S Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 0–153（154 aa）
Chain J 0–153（154 aa）
Mutation：C6A, C111S Mutation：C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；Ammonium Sulfate, NaCl, Tris, EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.00 Å R-free 0.250
1N19 Structure of the HSOD A4V mutant Deposited 2002-10-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 0–153（154 aa）
Chain B 0–153（154 aa）
Mutation：A4V, C6A, C111S Mutation：A4V, C6A, C111S CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；ammonium sulfate, NaCl, Tris, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.86 Å R-free 0.260
1OEZ Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase Deposited 2003-04-02 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain Y 1–153（153 aa）
Chain Z 1–153（153 aa）
Mutation：YES Mutation：YES ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2M NA2SO4, 15% PEG 3350, pH 8.00
Resolution 2.15 Å R-free 0.234
1OEZ Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase Deposited 2003-04-02 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain W 1–153（153 aa）
Chain X 1–153（153 aa）
Mutation：YES Mutation：YES ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；0.2M NA2SO4, 15% PEG 3350, pH 8.00
Resolution 2.15 Å R-free 0.234
1OZT Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution Deposited 2003-04-09 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain M 1–153（153 aa）
Chain N 1–153（153 aa）
Mutation：H46R Mutation：H46R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；magnesium acetate, sodium cacodylate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.50 Å R-free 0.270
1OZT Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution Deposited 2003-04-09 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–153（153 aa）
Chain H 1–153（153 aa）
Mutation：H46R Mutation：H46R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；magnesium acetate, sodium cacodylate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.50 Å R-free 0.270
1OZT Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution Deposited 2003-04-09 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 1–153（153 aa）
Chain L 1–153（153 aa）
Mutation：H46R Mutation：H46R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；magnesium acetate, sodium cacodylate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.50 Å R-free 0.270
1OZT Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution Deposited 2003-04-09 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–153（153 aa）
Chain J 1–153（153 aa）
Mutation：H46R Mutation：H46R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；magnesium acetate, sodium cacodylate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.50 Å R-free 0.270
1OZU Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution Deposited 2003-04-09 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：S134N Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：S134N Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 3 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；Ammonium sulfate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
Resolution 1.30 Å R-free 0.193
1P1V Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A Deposited 2003-04-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：D125H Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：D125H Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 2 ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；278 K；zinc sulfate, PEG MME 550, MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
Resolution 1.40 Å R-free 0.212
1P1V Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A Deposited 2003-04-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Mutation：D125H Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 2 ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；278 K；zinc sulfate, PEG MME 550, MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
Resolution 1.40 Å R-free 0.212
1PTZ Crystal structure of the human CU, Zn Superoxide Dismutase, Familial Amyotrophic Lateral Sclerosis (FALS) Mutant H43R Deposited 2003-06-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：C6A, C111S, H43R Mutation：C6A, C111S, H43R CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；294 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
Resolution 1.80 Å R-free 0.215
1PU0 Structure of Human Cu,Zn Superoxide Dismutase Deposited 2003-06-23 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Not recorded CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.70 Å R-free 0.243
1PU0 Structure of Human Cu,Zn Superoxide Dismutase Deposited 2003-06-23 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain D 1–153（153 aa）
Not recorded CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.70 Å R-free 0.243
1PU0 Structure of Human Cu,Zn Superoxide Dismutase Deposited 2003-06-23 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain F 1–153（153 aa）
Not recorded CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.70 Å R-free 0.243
1PU0 Structure of Human Cu,Zn Superoxide Dismutase Deposited 2003-06-23 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–153（153 aa）
Chain H 1–153（153 aa）
Not recorded CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.70 Å R-free 0.243
1PU0 Structure of Human Cu,Zn Superoxide Dismutase Deposited 2003-06-23 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–153（153 aa）
Chain J 1–153（153 aa）
Not recorded CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulphate, sodium chloride, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.70 Å R-free 0.243
1RK7 Solution structure of apo Cu,Zn Superoxide Dismutase: role of metal ions in protein folding Deposited 2003-11-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–153（153 aa）
Mutation：C6A, F50E, G51E, C111S, E133Q No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；298 K；Pressure 1
NMR sample composition Apo SOD 2mM | 20mM phosphate buffer pH5.0, 10% D2O
NMR sample composition Apo SOD 2mM enriched in 15N | 20mM phosphate buffer pH5.0, 10% D2O
NMR sample composition Apo SOD 2mM enriched in 15N and 13C | 20mM phosphate buffer pH5.0, 10% D2O
Resolution not provided
1SOS ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE Deposited 1992-02-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1SOS ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE Deposited 1992-02-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–153（153 aa）
Chain G 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1SOS ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE Deposited 1992-02-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain H 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1SOS ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE Deposited 1992-02-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–153（153 aa）
Chain I 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1SOS ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE Deposited 1992-02-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain J 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1SPD AMYOTROPHIC LATERAL SCLEROSIS AND STRUCTURAL DEFECTS IN CU,ZN SUPEROXIDE DISMUTASE Deposited 1993-07-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.40 Å
1UXL I113T mutant of human SOD1 Deposited 2004-02-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；100 MM NACL, 2.4M AMMONIUM SULPHATE PH 7.5
Resolution 1.60 Å R-free 0.196
1UXL I113T mutant of human SOD1 Deposited 2004-02-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–153（153 aa）
Chain G 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；100 MM NACL, 2.4M AMMONIUM SULPHATE PH 7.5
Resolution 1.60 Å R-free 0.196
1UXL I113T mutant of human SOD1 Deposited 2004-02-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain H 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；100 MM NACL, 2.4M AMMONIUM SULPHATE PH 7.5
Resolution 1.60 Å R-free 0.196
1UXL I113T mutant of human SOD1 Deposited 2004-02-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–153（153 aa）
Chain I 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；100 MM NACL, 2.4M AMMONIUM SULPHATE PH 7.5
Resolution 1.60 Å R-free 0.196
1UXL I113T mutant of human SOD1 Deposited 2004-02-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain J 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；100 MM NACL, 2.4M AMMONIUM SULPHATE PH 7.5
Resolution 1.60 Å R-free 0.196
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain D 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain F 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–153（153 aa）
Chain H 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–153（153 aa）
Chain J 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
1UXM A4V mutant of human SOD1 Deposited 2004-02-26 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 1–153（153 aa）
Chain L 1–153（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；0.2 M CA ACET, 15% PEG 2000, 0.1 M TRIS PH 8.0
Resolution 1.90 Å R-free 0.250
2AF2 Solution structure of disulfide reduced and copper depleted Human Superoxide Dismutase Deposited 2005-07-25 Different construct Different mutation/modification Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：C6A, C111S Mutation：C6A, C111S ZN ZINC ION × 2 SOLUTION NMR
NMR measurement conditions pH 5；298 K；Ionic strength (raw mmCIF value) 20mM sodium phosphate；Pressure 1
NMR sample composition 1.5mM 15N protein sample | 20mM sodium phosphate, 20mM DTT buffer, pH 5, 90% H2O, 10% D2O
NMR sample composition 1mM 15N;13C protein sample | 20mM sodium phosphate, 20mM DTT buffer, pH 5, 90% H2O, 10% D2O
NMR sample composition 1mM 15N;13C;2H protein sample. The triple labeled dimeric SOD contained about 70% 2H | 20mM sodium phosphate, 20mM DTT, buffer, pH 5, 90% H2O, 10% D2O
Resolution not provided
2C9S 1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase Deposited 2005-12-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 6 ACT ACETATE ION × 3 SO4 SULFATE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；2.5M AMMONIUM SULPHATE,0.1M NACL,50MM ACETATE BUFFER, pH 4.75
Resolution 1.24 Å R-free 0.194
2C9U 1.24 Angstroms resolution structure of as-isolated Cu-Zn Human Superoxide dismutase Deposited 2005-12-14 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Not recorded SO4 SULFATE ION × 3 CU COPPER (II) ION × 2 ZN ZINC ION × 4 ACT ACETATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；3.0 M AMMONIUM SULPHATE, 100 MM SODIUM CHLORITE, 50MM SODIUM ACETATE BUFFER, pH 8.00
Resolution 1.24 Å R-free 0.176
2C9V Atomic resolution structure of Cu-Zn Human Superoxide dismutase Deposited 2005-12-14 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 5 NA SODIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；3.0M AMMONIUM SULPHATE, 0.1M NACL, 50MM ACETATE BUFFER, pH 4.75
Resolution 1.07 Å R-free 0.158
2GBT C6A/C111A CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：C6A/C111A Mutation：C6A/C111A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；18% PEG8000, 50mM TRIS-HCL, 50mM NaAc, 1mM EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 1.70 Å R-free 0.230
2GBT C6A/C111A CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain D 1–153（153 aa）
Mutation：C6A/C111A Mutation：C6A/C111A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；18% PEG8000, 50mM TRIS-HCL, 50mM NaAc, 1mM EDTA, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 1.70 Å R-free 0.230
2GBU C6A/C111A/C57A/C146A apo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；25% PEG4000, 0.1M Na Cacodylate, 50mM NaAc, 1mM EDTA, 1mM NaN3, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.257
2GBU C6A/C111A/C57A/C146A apo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain D 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；25% PEG4000, 0.1M Na Cacodylate, 50mM NaAc, 1mM EDTA, 1mM NaN3, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.257
2GBV C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；2.8M Ammonium Sulphate, 50mM NaAc, 0.1M TRIS-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.207
2GBV C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–153（153 aa）
Chain G 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；2.8M Ammonium Sulphate, 50mM NaAc, 0.1M TRIS-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.207
2GBV C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain H 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；2.8M Ammonium Sulphate, 50mM NaAc, 0.1M TRIS-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.207
2GBV C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–153（153 aa）
Chain I 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；2.8M Ammonium Sulphate, 50mM NaAc, 0.1M TRIS-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.207
2GBV C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase Deposited 2006-03-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–153（153 aa）
Chain J 1–153（153 aa）
Mutation：C6A/C111A/C57A/C146A Mutation：C6A/C111A/C57A/C146A CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；2.8M Ammonium Sulphate, 50mM NaAc, 0.1M TRIS-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.00 Å R-free 0.207
2LU5 Structure and chemical shifts of Cu(I),Zn(II) superoxide dismutase by solid-state NMR Deposited 2012-06-08 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：C6A, C111S CU COPPER (II) ION × 1 SOLID-STATE NMR
NMR measurement conditions pH 5；286 K；Ionic strength (raw mmCIF value) 0.02；Pressure ambient
NMR sample composition 3.5 mg [U-13C; U-15N; U-2H] Superoxide dismutase C6A/C111S thermostable mutant, 20 mM Sodium Citrate, 20% w/v Polyethylene Glycol 6000, 100% H2O | 100% H2O
Resolution not provided
2MP3 Truncated L126Z-sod1 in DPC micelle Deposited 2014-05-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–126（125 aa） Fragment：UNP residues 2-126
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 4；313 K；Pressure ambient
NMR sample composition 20 mM dodecylphosphocholine (DPC)-1, 400 uM [U-100% 13C; U-100% 15N] protein-2, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2NAM Full-length WT SOD1 in DPC MICELLE Deposited 2016-01-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 4；313 K；Ionic strength (raw mmCIF value) 0；Pressure ambient
NMR sample composition 20 mM DPC-1, 0.4 mM [U-13C; U-15N] entity-2, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2NNX Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase Deposited 2006-10-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain B 1–153（153 aa）
Mutation：H46R, H48Q Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：H46R, H48Q Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；298 K；25% PEG 550MME, 0.1M MES, 0.01M zinc sulfate, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.30 Å R-free 0.241
2NNX Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase Deposited 2006-10-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–153（153 aa）
Chain D 1–153（153 aa）
Mutation：H46R, H48Q Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：H46R, H48Q Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 4 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；298 K；25% PEG 550MME, 0.1M MES, 0.01M zinc sulfate, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.30 Å R-free 0.241
2R27 Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S Deposited 2007-08-24 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Mutation：C7A, H81S, D84S, C112S Mutation：C7A, H81S, D84S, C112S CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；295 K；2.45 M ammonium sulfate, 200 mM NaCl in 50 mM Tris, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.00 Å R-free 0.246
2V0A Atomic resolution crystal structure of Human Superoxide Dismutase Deposited 2007-05-11 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–153（153 aa）
Chain F 1–153（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 3 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；3.5 M AMMONIUM SULPHATE, 100MM NACL, 50MM ACETATE BUFFER PH 4.75
Resolution 1.15 Å R-free 0.206
2VR6 Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution Deposited 2008-03-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：RESIDUES 2-154
Chain F 2–154（153 aa） Fragment：RESIDUES 2-154
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 4 SO4 SULFATE ION × 2 SCN THIOCYANATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；20% P3350 0.2 M NA THYOCYANATE, pH 7.0
Resolution 1.30 Å R-free 0.182
2VR7 Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution Deposited 2008-03-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：RESIDUES 2-154
Chain F 2–154（153 aa） Fragment：RESIDUES 2-154
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 6 SO4 SULFATE ION × 2 SCN THIOCYANATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；20% PEG3350, 0.2M SODIUM THIOCYANATE, pH 7.0
Resolution 1.58 Å R-free 0.175
2VR8 Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution Deposited 2008-03-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：RESIDUES 2-154
Chain F 2–154（153 aa） Fragment：RESIDUES 2-154
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 6 SO4 SULFATE ION × 2 SCN THIOCYANATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；20% PEG3350, 0.2M SODIUM THIOCYANATE, pH 7.0
Resolution 1.36 Å R-free 0.153
2WKO Structure of metal loaded Pathogenic SOD1 Mutant G93A. Deposited 2009-06-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：RESIDUES 2-154
Chain F 2–154（153 aa） Fragment：RESIDUES 2-154
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 IOD IODIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；20% P3350, 0.2 M AMMONIUM IODIDE, pH 6.5
Resolution 1.97 Å R-free 0.231
2WYT 1.0 A resolution structure of L38V SOD1 mutant Deposited 2009-11-20 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 4 SO4 SULFATE ION × 6 ACT ACETATE ION × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；150 MM NACL, 2-3M AMMONIUM SULPHATE, 100 MM NA ACETATE BUFFER PH 4.75
Resolution 1.00 Å R-free 0.147
2WYZ L38V SOD1 mutant complexed with UMP Deposited 2009-11-20 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 4 CU COPPER (II) ION × 2 SO4 SULFATE ION × 4 U5P URIDINE-5'-MONOPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；150 MM NACL, 3.0 M AMMONIUM SULPHATE, 100 MM TRIS PH 7.5
Resolution 1.70 Å R-free 0.239
2WZ0 L38V SOD1 mutant complexed with aniline. Deposited 2009-11-20 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 3 SO4 SULFATE ION × 2 ZZT 2-METHOXY-5-METHYLANILINE × 2 DMS DIMETHYL SULFOXIDE × 1 DSN D-SERINE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；150 MM NACL,3.0 M AMMONIUM SULPHATE, 100 MM TRIS-HCL PH 7.5
Resolution 1.72 Å R-free 0.260
2WZ5 L38V SOD1 mutant complexed with L-methionine. Deposited 2009-11-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES ZN ZINC ION × 3 CU COPPER (II) ION × 2 SO4 SULFATE ION × 3 MET METHIONINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；150 MM NACL, 2.0-3.0 M AMMONIUM SULPHATE, 100 MM ACETATE BUFFER PH 4.75
Resolution 1.50 Å R-free 0.255
2WZ6 G93A SOD1 mutant complexed with Quinazoline. Deposited 2009-11-23 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES ZN ZINC ION × 4 CU COPPER (II) ION × 2 ZO0 4-(4-METHYL-1,4-DIAZEPAN-1-YL)-2-(TRIFLUOROMETHYL)QUINAZOLINE × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.75；150 MM NACL, 2.0-3.0 M AMMONIUM SULPHATE, 100 MM ACETATE BUFFER PH 4.75
Resolution 1.55 Å R-free 0.248
2XJK Monomeric Human Cu,Zn Superoxide dismutase Deposited 2010-07-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：YES CU COPPER (II) ION × 1 ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；25% PEG 6000, 0.1M MES (PH 6.0), 0.01M ZNCL2
Resolution 1.45 Å R-free 0.199
2XJL Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands Deposited 2010-07-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：YES ZN ZINC ION × 4 PEG DI(HYDROXYETHYL)ETHER × 1 NA SODIUM ION × 2 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；25% PEG 6000, 0.1M SODIUM ACETATE (PH 5.0), 0.01M ZNCL2
Resolution 1.55 Å R-free 0.183
2ZKW Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21 Deposited 2008-03-31 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Mutation：G85R Mutation：G85R CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.2；293 K；0.2M Ammonium iodide, 20%(w/v) PEG3350, pH 6.2, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 1.90 Å R-free 0.252
2ZKX Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121 Deposited 2008-03-31 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Mutation：G85R Mutation：G85R CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.1M Sodium Acetate(pH 4.6), 1.5M Ammonium Sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.72 Å R-free 0.246
2ZKX Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121 Deposited 2008-03-31 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Mutation：G85R Mutation：G85R CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.1M Sodium Acetate(pH 4.6), 1.5M Ammonium Sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.72 Å R-free 0.246
2ZKY Crystal structure of human Cu-Zn superoxide dismutase mutant G93A Deposited 2008-03-31 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1M Cacodylate(pH 6.5), 0.2M NaCl, 2.0M Ammonium sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.235
2ZKY Crystal structure of human Cu-Zn superoxide dismutase mutant G93A Deposited 2008-03-31 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1M Cacodylate(pH 6.5), 0.2M NaCl, 2.0M Ammonium sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.235
2ZKY Crystal structure of human Cu-Zn superoxide dismutase mutant G93A Deposited 2008-03-31 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain F 1–154（154 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1M Cacodylate(pH 6.5), 0.2M NaCl, 2.0M Ammonium sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.235
2ZKY Crystal structure of human Cu-Zn superoxide dismutase mutant G93A Deposited 2008-03-31 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–154（154 aa）
Chain H 1–154（154 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1M Cacodylate(pH 6.5), 0.2M NaCl, 2.0M Ammonium sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.235
2ZKY Crystal structure of human Cu-Zn superoxide dismutase mutant G93A Deposited 2008-03-31 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.1M Cacodylate(pH 6.5), 0.2M NaCl, 2.0M Ammonium sulfate, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.40 Å R-free 0.235
3CQP Human SOD1 G85R Variant, Structure I Deposited 2008-04-03 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M sodium malonate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.95 Å R-free 0.223
3CQP Human SOD1 G85R Variant, Structure I Deposited 2008-04-03 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 MLI MALONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M sodium malonate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.95 Å R-free 0.223
3CQQ Human SOD1 G85R Variant, Structure II Deposited 2008-04-03 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 3 ACE ACETYL GROUP × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M sodium malonate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.90 Å R-free 0.240
3ECU Crystal structure of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；289.1 K；0.1 M MES 20% PEG 3350, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 1.90 Å R-free 0.279
3ECU Crystal structure of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；289.1 K；0.1 M MES 20% PEG 3350, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 1.90 Å R-free 0.279
3ECV Crystal structure of the ALS-related pathological mutant I113T of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；289.1 K；0.1 M MES 20% PEG 3350 , pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 1.90 Å R-free 0.277
3ECV Crystal structure of the ALS-related pathological mutant I113T of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；289.1 K；0.1 M MES 20% PEG 3350 , pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 1.90 Å R-free 0.277
3ECW Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；289.1 K；0.1 M HEPES 20% PEG 3350, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 2.15 Å R-free 0.297
3ECW Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1) Deposited 2008-09-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；289.1 K；0.1 M HEPES 20% PEG 3350, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 289.1K
Resolution 2.15 Å R-free 0.297
3GQF Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q Deposited 2009-03-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：H46R, H48Q Mutation：H46R, H48Q ZN ZINC ION × 2 CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；297 K；20% polyethylene glycol 1000, imidazole pH 8.0, calcium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 297K
Resolution 2.20 Å R-free 0.242
3GQF Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q Deposited 2009-03-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Mutation：H46R, H48Q Mutation：H46R, H48Q ZN ZINC ION × 2 CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；297 K；20% polyethylene glycol 1000, imidazole pH 8.0, calcium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 297K
Resolution 2.20 Å R-free 0.242
3GQF Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q Deposited 2009-03-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：H46R, H48Q Mutation：H46R, H48Q ZN ZINC ION × 2 CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；297 K；20% polyethylene glycol 1000, imidazole pH 8.0, calcium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 297K
Resolution 2.20 Å R-free 0.242
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain B 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain D 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain F 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain H 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain J 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GTV Human-mouse SOD1 chimera Deposited 2009-03-28 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Chain L 2–81（80 aa） Fragment：residues 2-81 from human protein, residues 82-154 from mouse protein
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；298 K；0.1 m HEPES, 25% PEG 8000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.231
3GZO HUMAN SOD1 G93A Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；2.4 M sodium malonate, pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.214
3GZO HUMAN SOD1 G93A Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；2.4 M sodium malonate, pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.214
3GZO HUMAN SOD1 G93A Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；2.4 M sodium malonate, pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.214
3GZO HUMAN SOD1 G93A Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Chain H 2–154（153 aa）
Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；2.4 M sodium malonate, pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.214
3GZO HUMAN SOD1 G93A Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain J 2–154（153 aa）
Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：G93A Non-standard monomer：Yes (specific site not provided by mmCIF) CU COPPER (II) ION × 2 ZN ZINC ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；2.4 M sodium malonate, pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.214
3GZP HUMAN SOD1 G93A Metal-free Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：G93A Mutation：G93A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M ammonium sulfate, 0.1 M HEPES, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 3.10 Å R-free 0.248
3GZP HUMAN SOD1 G93A Metal-free Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Mutation：G93A Mutation：G93A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M ammonium sulfate, 0.1 M HEPES, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 3.10 Å R-free 0.248
3GZQ HUMAN SOD1 A4V Metal-free Variant Deposited 2009-04-07 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：A4V Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：A4V Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；1.6 M ammonium sulfate, 0.1 M MES, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.40 Å R-free 0.193
3H2P Human SOD1 D124V Variant Deposited 2009-04-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：D124V Mutation：D124V ZN ZINC ION × 3 MLI MALONATE ION × 2 ACE ACETYL GROUP × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；2.4 M sodium malonate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.55 Å R-free 0.202
3H2Q Human SOD1 H80R variant, P21 crystal form Deposited 2009-04-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：H80R Mutation：H80R ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；298 K；2.3 M AMMONIUM SULFATE, 0.1 M Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.85 Å R-free 0.222
3H2Q Human SOD1 H80R variant, P21 crystal form Deposited 2009-04-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Mutation：H80R Mutation：H80R ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；298 K；2.3 M AMMONIUM SULFATE, 0.1 M Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.85 Å R-free 0.222
3HFF Monomeric human Cu,Zn Superoxide dismutase without Zn ligands Deposited 2009-05-11 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：C6A, C111A, F50E, G51E, H63S, H71S, H80S, D83S ZN ZINC ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；16% PEG 6000, 10% Jeffamine M-600 (pH 7.0), 0.1M Tris-HCl (pH 8.0), 0.1M ZnCl2, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.20 Å R-free 0.281
3HFF Monomeric human Cu,Zn Superoxide dismutase without Zn ligands Deposited 2009-05-11 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Mutation：C6A, C111A, F50E, G51E, H63S, H71S, H80S, D83S ZN ZINC ION × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；16% PEG 6000, 10% Jeffamine M-600 (pH 7.0), 0.1M Tris-HCl (pH 8.0), 0.1M ZnCl2, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.20 Å R-free 0.281
3K91 Polysulfane Bridge in Cu-Zn Superoxide Dismutase Deposited 2009-10-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：H46R, H48Q Mutation：H46R, H48Q PS5 PENTASULFIDE-SULFUR × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；298 K；0.17 M ammonium sulfate, 0.085 M sodium acetate, 25.5% PEG 4000, 15% glycerol, pH 4.6, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 1.75 Å R-free 0.218
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Chain H 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain J 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH3 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 2–154（153 aa）
Chain L 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.277
3KH4 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P6522 crystal form containing 6 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.208
3KH4 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P6522 crystal form containing 6 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.208
3KH4 Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P6522 crystal form containing 6 chains in the asymmetric unit Deposited 2009-10-30 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；292 K；21-25% (w/v) PEG4000, 0.1 M NaOAc, pH 4.2-5.2, vapor diffusion, hanging drop, temperature 292K
Resolution 3.50 Å R-free 0.208
3LTV Mouse-human sod1 chimera Deposited 2010-02-16 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Chain B 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；0.1 M SODIUM ACETATE, 25% PEG 4000, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.45 Å R-free 0.265
3LTV Mouse-human sod1 chimera Deposited 2010-02-16 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Chain D 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；0.1 M SODIUM ACETATE, 25% PEG 4000, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.45 Å R-free 0.265
3LTV Mouse-human sod1 chimera Deposited 2010-02-16 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Chain F 82–154（73 aa） Fragment：;RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN,RESIDUES 2-81 FROM MOUSE PROTEIN, RESIDUES 82-154 FROM HUMAN PROTEIN ;
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；0.1 M SODIUM ACETATE, 25% PEG 4000, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.45 Å R-free 0.265
3QQD Human SOD1 H80R variant, P212121 crystal form Deposited 2011-02-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；2.3 M AMMONIUM SULFATE, 0.1 M TRIS, TEMPERATURE 298K, pH 8.0, VAPOR DIFFUSION, HANGING DROP
Resolution 1.65 Å R-free 0.183
3RE0 Crystal structure of human apo Cu,Zn superoxide dismutase (SOD1) complexed with cisplatin Deposited 2011-04-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CPT Cisplatin × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；20% PEG 3350, 0.1M HEPES, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.28 Å R-free 0.290
3RE0 Crystal structure of human apo Cu,Zn superoxide dismutase (SOD1) complexed with cisplatin Deposited 2011-04-02 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded CPT Cisplatin × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；20% PEG 3350, 0.1M HEPES, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.28 Å R-free 0.290
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 2–154（153 aa）
Chain E 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 2–154（153 aa）
Chain G 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain H 2–154（153 aa）
Chain I 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain J 2–154（153 aa）
Chain K 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
3T5W 2ME modified human SOD1 Deposited 2011-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain L 2–154（153 aa）
Chain M 2–154（153 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) CU1 COPPER (I) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；289 K；15% PEG 3350, 300mM (NH4)2SO4, pH6.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.80 Å R-free 0.241
4A7G Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group. Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES SO4 SULFATE ION × 5 12I 4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLINE × 3 CU COPPER (II) ION × 2 ZN ZINC ION × 2 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100MM SODIUM ACETATE PH 5, 150 MM SODIUM CHLORIDE, 2.5 M AMMONIUM SULPHATE
Resolution 1.24 Å R-free 0.175
4A7Q Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group. Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES 4MQ 4-(4-METHYL-1,4-DIAZEPAN-1-YL)QUINAZOLINE × 2 SO4 SULFATE ION × 6 CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100 MM SODIUM ACETATE PH 5, 150 MM SODIUM CHLORIDE, 2.5 AMMONIUM SULPHATE
Resolution 1.22 Å R-free 0.159
4A7S Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 5 ACT ACETATE ION × 2 5UD 5-FLUOROURIDINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100 MM SODIUM ACETATE, 150 MM SODIUM CHLORIDE, 2.5 AMMONIUM SULPHATE PH 5
Resolution 1.06 Å R-free 0.200
4A7T Structure of human I113T SOD1 mutant complexed with isoproteranol in the p21 space group Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES 5FW ISOPRENALINE × 5 SO4 SULFATE ION × 4 ACT ACETATE ION × 2 CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100 MM SODIUM ACETATE PH 5, 150 MM SODIUM CHLORIDE, 2.5 AMMONIUM SULPHATE
Resolution 1.45 Å R-free 0.188
4A7U Structure of human I113T SOD1 complexed with adrenaline in the p21 space group. Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES ALE L-EPINEPHRINE × 2 SO4 SULFATE ION × 4 CU COPPER (II) ION × 2 ZN ZINC ION × 2 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100 MM SODIUM ACETATE, 150 MM SODIUM CHLORIDE, 2.5 AMMONIUM SULPHATE PH 5
Resolution 0.98 Å R-free 0.153
4A7V Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group Deposited 2011-11-14 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：YES Mutation：YES LDP L-DOPAMINE × 1 SO4 SULFATE ION × 4 CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5；100 MM SODIUM ACETATE, 150 MM SODIUM CHLORIDE, 2.5 M AMMONIUM SULPHATE PH 5
Resolution 1.00 Å R-free 0.181
4B3E Structure of copper-zinc superoxide dismutase complexed with bicarbonate. Deposited 2012-07-23 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain F 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CO3 CARBONATE ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；1 M AMMONIUM SULPHATE, 50 MM TRIS PH 8.0 AND 50 MM NACL
Resolution 2.15 Å R-free 0.215
4B3E Structure of copper-zinc superoxide dismutase complexed with bicarbonate. Deposited 2012-07-23 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–154（154 aa）
Chain G 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CO3 CARBONATE ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；1 M AMMONIUM SULPHATE, 50 MM TRIS PH 8.0 AND 50 MM NACL
Resolution 2.15 Å R-free 0.215
4B3E Structure of copper-zinc superoxide dismutase complexed with bicarbonate. Deposited 2012-07-23 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CO3 CARBONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；1 M AMMONIUM SULPHATE, 50 MM TRIS PH 8.0 AND 50 MM NACL
Resolution 2.15 Å R-free 0.215
4B3E Structure of copper-zinc superoxide dismutase complexed with bicarbonate. Deposited 2012-07-23 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–154（154 aa）
Chain I 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CO3 CARBONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；1 M AMMONIUM SULPHATE, 50 MM TRIS PH 8.0 AND 50 MM NACL
Resolution 2.15 Å R-free 0.215
4B3E Structure of copper-zinc superoxide dismutase complexed with bicarbonate. Deposited 2012-07-23 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 CO3 CARBONATE ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；1 M AMMONIUM SULPHATE, 50 MM TRIS PH 8.0 AND 50 MM NACL
Resolution 2.15 Å R-free 0.215
4BCY Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F Deposited 2012-10-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：YES CU COPPER (II) ION × 2 ZN ZINC ION × 1 CD CADMIUM ION × 6 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions 293 K；25% PEG 400, 0.1M NA ACETATE PH 4.6, 0.1 M CDCL2, 20 C
Resolution 1.27 Å R-free 0.203
4BCZ Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. Deposited 2012-10-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–49（48 aa） Fragment：RESIDUES 2049,83-124,141-154
Chain A 83–124（42 aa） Fragment：RESIDUES 2049,83-124,141-154
Chain A 141–154（14 aa） Fragment：RESIDUES 2049,83-124,141-154
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 293 K；30% PEG 1500, 0.1M MIB BUFFER, PH 4.0, 20 C
Resolution 1.93 Å R-free 0.220
4BCZ Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. Deposited 2012-10-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–49（48 aa） Fragment：RESIDUES 2049,83-124,141-154
Chain B 83–124（42 aa） Fragment：RESIDUES 2049,83-124,141-154
Chain B 141–154（14 aa） Fragment：RESIDUES 2049,83-124,141-154
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 293 K；30% PEG 1500, 0.1M MIB BUFFER, PH 4.0, 20 C
Resolution 1.93 Å R-free 0.220
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–49（48 aa）
Chain A 83–124（42 aa）
Chain A 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–49（48 aa）
Chain B 83–124（42 aa）
Chain B 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 2–49（48 aa）
Chain C 83–124（42 aa）
Chain C 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 2–49（48 aa）
Chain D 83–124（42 aa）
Chain D 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 2–49（48 aa）
Chain E 83–124（42 aa）
Chain E 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 2–49（48 aa）
Chain F 83–124（42 aa）
Chain F 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 2–49（48 aa）
Chain G 83–124（42 aa）
Chain G 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 2–49（48 aa）
Chain H 83–124（42 aa）
Chain H 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4BD4 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F Deposited 2012-10-04 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 2–49（48 aa）
Chain I 83–124（42 aa）
Chain I 141–154（14 aa）
Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions 18 % PEG 1500, 15% GLYCEROL
Resolution 2.78 Å R-free 0.246
4FF9 Crystal Structure of cysteinylated WT SOD1. Deposited 2012-05-31 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CYS CYSTEINE × 1 ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.25；298 K；0.1M MES, pH 6.25, 20% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.50 Å R-free 0.335
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：UNP residues 2-154
Chain B 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa） Fragment：UNP residues 2-154
Chain D 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa） Fragment：UNP residues 2-154
Chain F 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa） Fragment：UNP residues 2-154
Chain H 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa） Fragment：UNP residues 2-154
Chain J 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCM Human SOD1 C57S Mutant, As-isolated Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 2–154（153 aa） Fragment：UNP residues 2-154
Chain L 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S ZN ZINC ION × 4 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295 K；0.2 M ammonium sulfate, 0.1 M bis-tris, 25% PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.20 Å R-free 0.262
4MCN Human SOD1 C57S Mutant, Metal-free Deposited 2013-08-21 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa） Fragment：UNP residues 2-154
Chain B 2–154（153 aa） Fragment：UNP residues 2-154
Mutation：C57S Mutation：C57S SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；3.2 M ammonium sulfate, 0.1 M MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.60 Å R-free 0.245
4NIN DSVISLS segment 101-107 from Human Superoxide Dismutase Deposited 2013-11-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 10 PDB declaration: decameric
Chain A 102–108（7 aa） Fragment：UNP residues 102-108
Not recorded ZN ZINC ION × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；0.1 M MES pH 6.0, 20% PEG 6000, and 5 mM ZnCl2, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.40 Å R-free 0.228
4NIO GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis Deposited 2013-11-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 10 PDB declaration: decameric
Chain A 148–154（7 aa） Fragment：UNP Residues 148-154
Mutation：I149T No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；0.1 M sodium acetate pH 4.5, 0.7 M hexanediol, vapor diffusion, hanging drop, temperature 298K
Resolution 1.30 Å R-free 0.233
4NIP GVIGIAQ segment 147-153 from Human Superoxide Dismutase Deposited 2013-11-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 10 PDB declaration: decameric
Chain A 148–154（7 aa） Fragment：UNP Residues 148-154
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；1 M sodium acetate pH 4.5, 1.75 M ammonium sulfate, vapor diffusion, hanging drop, temperature 298K
Resolution 1.90 Å R-free 0.248
4OH2 Crystal Structure of Cu/Zn Superoxide Dismutase I149T Deposited 2014-01-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：C6A, C111S, L149T Mutation：C6A, C111S, L149T CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；298 K；100mM NaCl, 100mM Tris-HCl pH 7.6, 2.8M (NH4)2SO4, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.38 Å R-free 0.216
4OH2 Crystal Structure of Cu/Zn Superoxide Dismutase I149T Deposited 2014-01-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain D 2–154（153 aa）
Mutation：C6A, C111S, L149T Mutation：C6A, C111S, L149T CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；298 K；100mM NaCl, 100mM Tris-HCl pH 7.6, 2.8M (NH4)2SO4, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.38 Å R-free 0.216
4OH2 Crystal Structure of Cu/Zn Superoxide Dismutase I149T Deposited 2014-01-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：C6A, C111S, L149T Mutation：C6A, C111S, L149T CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；298 K；100mM NaCl, 100mM Tris-HCl pH 7.6, 2.8M (NH4)2SO4, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.38 Å R-free 0.216
4OH2 Crystal Structure of Cu/Zn Superoxide Dismutase I149T Deposited 2014-01-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Chain H 2–154（153 aa）
Mutation：C6A, C111S, L149T Mutation：C6A, C111S, L149T CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；298 K；100mM NaCl, 100mM Tris-HCl pH 7.6, 2.8M (NH4)2SO4, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.38 Å R-free 0.216
4OH2 Crystal Structure of Cu/Zn Superoxide Dismutase I149T Deposited 2014-01-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain J 2–154（153 aa）
Mutation：C6A, C111S, L149T Mutation：C6A, C111S, L149T CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；298 K；100mM NaCl, 100mM Tris-HCl pH 7.6, 2.8M (NH4)2SO4, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.38 Å R-free 0.216
4XCR Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A Deposited 2014-12-18 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Mutation：I45A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；293 K；0.1 M Bis Tris and 2.0 M ammonium sulfate
Resolution 3.60 Å R-free 0.239
4XCR Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A Deposited 2014-12-18 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–154（153 aa）
Mutation：I45A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；293 K；0.1 M Bis Tris and 2.0 M ammonium sulfate
Resolution 3.60 Å R-free 0.239
5DLI Corkscrew assembly of SOD1 residues 28-38 Deposited 2015-09-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 8 PDB declaration: octameric
Chain A 29–39（11 aa） Fragment：Residues 29-39
Chain B 29–39（11 aa） Fragment：Residues 29-39
Chain C 29–39（11 aa） Fragment：Residues 29-39
Chain D 29–39（11 aa） Fragment：Residues 29-39
Chain E 29–39（11 aa） Fragment：Residues 29-39
Chain F 29–39（11 aa） Fragment：Residues 29-39
Chain G 29–39（11 aa） Fragment：Residues 29-39
Chain H 29–39（11 aa） Fragment：Residues 29-39
Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K GOL GLYCEROL × 1 IOD IODIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；298 K；reservoir contained 13% PEG 6000, 0.2M Sodium Citrate
Resolution 2.10 Å R-free 0.262
5IIW Corkscrew assembly of SOD1 residues 28-38 without potassium iodide Deposited 2016-03-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 8 PDB declaration: octameric
Chain A 29–39（11 aa） Fragment：UNP Residues 29-39
Chain B 29–39（11 aa） Fragment：UNP Residues 29-39
Chain C 29–39（11 aa） Fragment：UNP Residues 29-39
Chain D 29–39（11 aa） Fragment：UNP Residues 29-39
Chain E 29–39（11 aa） Fragment：UNP Residues 29-39
Chain F 29–39（11 aa） Fragment：UNP Residues 29-39
Chain G 29–39（11 aa） Fragment：UNP Residues 29-39
Chain H 29–39（11 aa） Fragment：UNP Residues 29-39
Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K Mutation：P29K No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；298 K；reservoir contained 13% PEG 6000, 0.2M Sodium Citrate
Resolution 2.00 Å R-free 0.252
5J07 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2 Deposited 2016-03-27 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 14–49（36 aa）
Chain A 84–124（41 aa）
Chain A 141–154（14 aa）
Chain A 2–13（12 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5；293 K；0.1 M MIB buffer pH 5.0 25 % w/v PEG 1500
Resolution 2.00 Å R-free 0.231
5J07 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2 Deposited 2016-03-27 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 14–49（36 aa）
Chain B 84–124（41 aa）
Chain B 141–154（14 aa）
Chain B 2–13（12 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5；293 K；0.1 M MIB buffer pH 5.0 25 % w/v PEG 1500
Resolution 2.00 Å R-free 0.231
5J0C Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3 Deposited 2016-03-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 29–49（21 aa）
Chain A 84–124（41 aa）
Chain A 2–26（25 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5；293 K；0.1 M MIB buffer pH 5.0 25 % w/v PEG 1500
Resolution 1.60 Å R-free 0.186
5J0C Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3 Deposited 2016-03-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 29–49（21 aa）
Chain B 84–124（41 aa）
Chain B 2–26（25 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5；293 K；0.1 M MIB buffer pH 5.0 25 % w/v PEG 1500
Resolution 1.60 Å R-free 0.186
5J0F Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5 Deposited 2016-03-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 83–124（42 aa）
Chain A 2–49（48 aa）
Not recorded GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；293 K；0.17 M ammonium sulfate, 25.5 % w/v PEG 4K, 15 % v/v Glycerol
Resolution 1.25 Å R-free 0.170
5J0F Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5 Deposited 2016-03-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 83–124（42 aa）
Chain B 2–49（48 aa）
Not recorded GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；293 K；0.17 M ammonium sulfate, 25.5 % w/v PEG 4K, 15 % v/v Glycerol
Resolution 1.25 Å R-free 0.170
5J0G Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 Deposited 2016-03-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–124（123 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M di-ammonium hydrogen citrate, 20 % w/v PEG 3350
Resolution 2.50 Å R-free 0.235
5J0G Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 Deposited 2016-03-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–124（123 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M di-ammonium hydrogen citrate, 20 % w/v PEG 3350
Resolution 2.50 Å R-free 0.235
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 10 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain Q 2–154（153 aa）
Chain V 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 11 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain R 2–154（153 aa）
Chain U 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 12 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain S 2–154（153 aa）
Chain T 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Chain L 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 2–154（153 aa）
Chain K 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain J 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 2–154（153 aa）
Chain I 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Chain H 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 7 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain M 2–154（153 aa）
Chain N 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 8 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain O 2–154（153 aa）
Chain X 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5K02 Structure of human SOD1 with T2D mutation Deposited 2016-05-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 9 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain P 2–154（153 aa）
Chain W 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；T2D was crystallized in a buffer of 2 M (NH4)2SO4, 0.1 M Sodium Cacodylate, 20% MPD and 10 mM ZnCl2 (pH 6.5) after a period of approximately 5 months.
Resolution 1.99 Å R-free 0.162
5O3Y SOD1 bound to Ebsulfur Deposited 2017-05-25 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded ZN ZINC ION × 4 9JK ~{N}-phenyl-2-sulfanyl-benzamide × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 3.75；293 K；100 mM NaAct pH 3.75, 100 mM NaCl, 2.8 M AmSO4
Resolution 1.30 Å R-free 0.186
5O40 SOD1 bound to Ebselen Deposited 2017-05-25 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded ZN ZINC ION × 4 9JT N-phenyl-2-selanylbenzamide × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4；293 K；100 mM NaACT pH 4, 2.4 M AMSO4, 150 mM NaCl
Resolution 1.50 Å R-free 0.215
5U9M Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site Deposited 2016-12-16 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Mutation：H46R,H48Q ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；25 % PEG 3350, 0.2 M ammonium sulfate, 0.1 M bis-tris pH 6.5
Resolution 2.35 Å R-free 0.235
5U9M Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site Deposited 2016-12-16 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Mutation：H46R,H48Q ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；25 % PEG 3350, 0.2 M ammonium sulfate, 0.1 M bis-tris pH 6.5
Resolution 2.35 Å R-free 0.235
5WMJ KVWGSI segment from Superoxide Dismutase 1,residues 30-35 Deposited 2017-07-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 8 PDB declaration: octameric
Chain A 31–36（6 aa） Fragment：UNP residues 31-36
Chain B 31–36（6 aa） Fragment：UNP residues 31-36
Not recorded TFA trifluoroacetic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；Reservoir solution contained 4M Sodium Formate
Resolution 1.40 Å R-free 0.170
5WOR Corkscrew assembly of SOD1 residues 28-38 with familial mutation G37R Deposited 2017-08-02 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 20 PDB declaration: eicosameric
Chain A 29–39（11 aa） Fragment：UNP residues 29-39
Chain B 29–39（11 aa） Fragment：UNP residues 29-39
Chain C 29–39（11 aa） Fragment：UNP residues 29-39
Chain D 29–39（11 aa） Fragment：UNP residues 29-39
Chain E 29–39（11 aa） Fragment：UNP residues 29-39
Chain F 29–39（11 aa） Fragment：UNP residues 29-39
Chain G 29–39（11 aa） Fragment：UNP residues 29-39
Chain H 29–39（11 aa） Fragment：UNP residues 29-39
Chain I 29–39（11 aa） Fragment：UNP residues 29-39
Chain J 29–39（11 aa） Fragment：UNP residues 29-39
Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R Mutation：P29K,G38R MLI MALONATE ION × 6 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；reservoir contained 15% PEG 3350, 0.3M Sodium Malonate
Resolution 2.77 Å R-free 0.247
5YTO Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. Deposited 2017-11-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 946 4-[(1~{R})-2-(naphthalen-2-ylmethylamino)-1-oxidanyl-ethyl]benzene-1,2-diol × 1 PS5 PENTASULFIDE-SULFUR × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, pH 6.0
Resolution 1.90 Å R-free 0.215
5YTO Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. Deposited 2017-11-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 1 946 4-[(1~{R})-2-(naphthalen-2-ylmethylamino)-1-oxidanyl-ethyl]benzene-1,2-diol × 1 PS5 PENTASULFIDE-SULFUR × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, pH 6.0
Resolution 1.90 Å R-free 0.215
5YTO Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. Deposited 2017-11-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain F 1–154（154 aa）
Not recorded ZN ZINC ION × 2 PS5 PENTASULFIDE-SULFUR × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, pH 6.0
Resolution 1.90 Å R-free 0.215
5YTO Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. Deposited 2017-11-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded ZN ZINC ION × 2 946 4-[(1~{R})-2-(naphthalen-2-ylmethylamino)-1-oxidanyl-ethyl]benzene-1,2-diol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, pH 6.0
Resolution 1.90 Å R-free 0.215
5YTO Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. Deposited 2017-11-19 Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, pH 6.0
Resolution 1.90 Å R-free 0.215
5YTU Structure of human SOD1 complexed with isoproteranol in C2221 space group Deposited 2017-11-20 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded 5FW ISOPRENALINE × 1 ZN ZINC ION × 2 TAM TRIS(HYDROXYETHYL)AMINOMETHANE × 1 S4P Dihydrogen tetrasulfide × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate, pH 6.0
Resolution 1.90 Å R-free 0.221
5YTU Structure of human SOD1 complexed with isoproteranol in C2221 space group Deposited 2017-11-20 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate, pH 6.0
Resolution 1.90 Å R-free 0.221
5YTU Structure of human SOD1 complexed with isoproteranol in C2221 space group Deposited 2017-11-20 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–154（154 aa）
Chain E 1–154（154 aa）
Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate, pH 6.0
Resolution 1.90 Å R-free 0.221
5YTU Structure of human SOD1 complexed with isoproteranol in C2221 space group Deposited 2017-11-20 Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Chain G 1–154（154 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate, pH 6.0
Resolution 1.90 Å R-free 0.221
5YTU Structure of human SOD1 complexed with isoproteranol in C2221 space group Deposited 2017-11-20 Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate, pH 6.0
Resolution 1.90 Å R-free 0.221
5YUL Native Structure of hSOD1 in P6322 space group Deposited 2017-11-22 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate pH 6.0
Resolution 1.90 Å R-free 0.227
5YUL Native Structure of hSOD1 in P6322 space group Deposited 2017-11-22 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate pH 6.0
Resolution 1.90 Å R-free 0.227
5YUL Native Structure of hSOD1 in P6322 space group Deposited 2017-11-22 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–154（154 aa）
Chain E 1–154（154 aa）
Not recorded ZN ZINC ION × 2 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate pH 6.0
Resolution 1.90 Å R-free 0.227
5YUL Native Structure of hSOD1 in P6322 space group Deposited 2017-11-22 Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Chain G 1–154（154 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate pH 6.0
Resolution 1.90 Å R-free 0.227
5YUL Native Structure of hSOD1 in P6322 space group Deposited 2017-11-22 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 1 S4P Dihydrogen tetrasulfide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；300 K；Sodium Citrate pH 6.0
Resolution 1.90 Å R-free 0.227
6B79 Curved pair of sheets formed from SOD1 residues 28-38 with familial mutation G37R. Deposited 2017-10-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 8 PDB declaration: octameric
Chain A 29–39（11 aa）
Chain B 29–39（11 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) ORA 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；HEPES pH 7.5, Sodium citrate, 2-Methyl-2,4-pentanediol
Resolution 1.80 Å R-free 0.267
6DTK Heterodimers of FALS mutant SOD enzyme Deposited 2018-06-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–154（154 aa）
Chain A 2–154（153 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；2-3 M Ammonium sulfate or Sodium malonate
Resolution 2.00 Å R-free 0.190
6DTK Heterodimers of FALS mutant SOD enzyme Deposited 2018-06-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 1–154（154 aa）
Chain C 2–154（153 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；2-3 M Ammonium sulfate or Sodium malonate
Resolution 2.00 Å R-free 0.190
6DTK Heterodimers of FALS mutant SOD enzyme Deposited 2018-06-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 1–154（154 aa）
Chain E 2–154（153 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；2-3 M Ammonium sulfate or Sodium malonate
Resolution 2.00 Å R-free 0.190
6DTK Heterodimers of FALS mutant SOD enzyme Deposited 2018-06-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 1–154（154 aa）
Chain G 2–154（153 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；2-3 M Ammonium sulfate or Sodium malonate
Resolution 2.00 Å R-free 0.190
6DTK Heterodimers of FALS mutant SOD enzyme Deposited 2018-06-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 1–154（154 aa）
Chain I 2–154（153 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；2-3 M Ammonium sulfate or Sodium malonate
Resolution 2.00 Å R-free 0.190
6FFK Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH Deposited 2018-01-08 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded D7Z PtCl2(1(R),2(R)-DACH) × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；0.1 M HEPES, 20% PEG 3350
Resolution 1.94 Å R-free 0.256
6FFK Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH Deposited 2018-01-08 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded D7Z PtCl2(1(R),2(R)-DACH) × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；0.1 M HEPES, 20% PEG 3350
Resolution 1.94 Å R-free 0.256
6FLH Monomeric Human Cu,Zn Superoxide dismutase, SOD1 7+7, apo form Deposited 2018-01-25 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–154（153 aa）
Not recorded SO4 SULFATE ION × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M sodium acetate pH 4.6 and 2 M ammonium sulfate
Resolution 1.79 Å R-free 0.197
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 2–154（153 aa）
Chain G 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain K 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain M 2–154（153 aa）
Chain O 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain Q 2–154（153 aa）
Chain S 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOI Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. Deposited 2018-02-07 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain U 2–154（153 aa）
Chain W 2–154（153 aa）
Not recorded ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Lithium sulphate 24% w/v PEG 4000 0.1 M Tris-HCl pH 8.0
Resolution 2.00 Å R-free 0.259
6FOL Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase Deposited 2018-02-07 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25% (w/v) PEG 1500 and 0.1 M PCTP buffer pH 7.0 (sodium propionate, sodium cacodylate, and BIS-TRIS propane in the molar ratios 2:1:2, respectively)
Resolution 2.55 Å R-free 0.248
6FOL Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase Deposited 2018-02-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 PE8 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25% (w/v) PEG 1500 and 0.1 M PCTP buffer pH 7.0 (sodium propionate, sodium cacodylate, and BIS-TRIS propane in the molar ratios 2:1:2, respectively)
Resolution 2.55 Å R-free 0.248
6FOL Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase Deposited 2018-02-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25% (w/v) PEG 1500 and 0.1 M PCTP buffer pH 7.0 (sodium propionate, sodium cacodylate, and BIS-TRIS propane in the molar ratios 2:1:2, respectively)
Resolution 2.55 Å R-free 0.248
6FOL Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase Deposited 2018-02-07 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25% (w/v) PEG 1500 and 0.1 M PCTP buffer pH 7.0 (sodium propionate, sodium cacodylate, and BIS-TRIS propane in the molar ratios 2:1:2, respectively)
Resolution 2.55 Å R-free 0.248
6FON Elongated conformer of the human copper chaperone for SOD1 complexed with human SOD1 Deposited 2018-02-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 2–154（153 aa）
Chain D 2–154（153 aa）
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；0.1 M MES pH 6.0 0.2 M Magnesium chloride 20 % (w/v) PEG 6000
Resolution 3.05 Å R-free 0.246
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 PPI PROPANOIC ACID × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 10 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain S 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 11 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 12 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 PPI PROPANOIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 PPI PROPANOIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 7 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain M 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 8 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain O 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6FP6 Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation Deposited 2018-02-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 9 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain Q 2–154（153 aa）
Mutation：C57A; C146A ZN ZINC ION × 2 PPI PROPANOIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M PCTP buffer pH 9.0, 20% (w/v) PEG 3350.
Resolution 3.00 Å R-free 0.230
6SPA A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP Deposited 2019-08-31 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain C 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 GOL GLYCEROL × 4 DMS DIMETHYL SULFOXIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 1.65 Å R-free 0.196
6SPA A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP Deposited 2019-08-31 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain G 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 GOL GLYCEROL × 6 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 1.65 Å R-free 0.196
6SPA A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP Deposited 2019-08-31 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain J 2–154（153 aa）
Chain L 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 GOL GLYCEROL × 2 DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 1.65 Å R-free 0.196
6SPH A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain C 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 9JT N-phenyl-2-selanylbenzamide × 2 GOL GLYCEROL × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 2.25 Å R-free 0.222
6SPH A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain G 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 9JT N-phenyl-2-selanylbenzamide × 2 GOL GLYCEROL × 3 SO4 SULFATE ION × 1 DMS DIMETHYL SULFOXIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 2.25 Å R-free 0.222
6SPH A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain J 2–154（153 aa）
Chain L 2–154（153 aa）
Mutation：Ala4Val Mutation：Ala4Val ZN ZINC ION × 2 9JT N-phenyl-2-selanylbenzamide × 2 GOL GLYCEROL × 2 SO4 SULFATE ION × 1 DMS DIMETHYL SULFOXIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；100 mM Tris-HCl pH 7.4-8.0, 2.4-2.6 M ammonium sulphate, 150 mM NaCl
Resolution 2.25 Å R-free 0.222
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain J 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain B 1–154（154 aa）
Chain K 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain I 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–154（154 aa）
Chain L 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain G 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPI A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 Deposited 2019-09-01 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Chain H 1–154（154 aa）
Mutation：A4V Mutation：A4V LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；100mM Tris-HCl pH 7.8, 2.6 M ammonium sulphate
Resolution 2.80 Å R-free 0.241
6SPJ A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 LR2 ~{N}-pyridin-2-yl-2-selanyl-benzamide × 2 SO4 SULFATE ION × 13 GOL GLYCEROL × 2 DMS DIMETHYL SULFOXIDE × 3 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 1.97 Å R-free 0.225
6SPJ A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 LR2 ~{N}-pyridin-2-yl-2-selanyl-benzamide × 2 SO4 SULFATE ION × 7 GOL GLYCEROL × 2 DMS DIMETHYL SULFOXIDE × 4 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 1.97 Å R-free 0.225
6SPJ A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain J 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 LR2 ~{N}-pyridin-2-yl-2-selanyl-benzamide × 2 SO4 SULFATE ION × 10 GOL GLYCEROL × 2 DMS DIMETHYL SULFOXIDE × 2 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 1.97 Å R-free 0.225
6SPK A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 2 LQN 2-selanyl-~{N}-[3-[4-(trifluoromethyl)phenyl]phenyl]benzamide × 2 SO4 SULFATE ION × 8 GOL GLYCEROL × 1 CL CHLORIDE ION × 3 DMS DIMETHYL SULFOXIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 2.77 Å R-free 0.229
6SPK A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 2 LQN 2-selanyl-~{N}-[3-[4-(trifluoromethyl)phenyl]phenyl]benzamide × 2 SO4 SULFATE ION × 10 CL CHLORIDE ION × 3 DMS DIMETHYL SULFOXIDE × 2 NA SODIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 2.77 Å R-free 0.229
6SPK A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6 Deposited 2019-09-01 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Chain J 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 3 LQN 2-selanyl-~{N}-[3-[4-(trifluoromethyl)phenyl]phenyl]benzamide × 2 SO4 SULFATE ION × 8 CL CHLORIDE ION × 3 NA SODIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；2.6 M Ammonium sulphate, 100 mM Tris-HCl pH 7.6, 150 mM NaCl
Resolution 2.77 Å R-free 0.229
6Z3V A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group Deposited 2020-05-22 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 Q6H 5-fluoranyl-~{N}-(3-morpholin-4-ylcarbonylphenyl)-2-selanyl-benzamide × 2 SO4 SULFATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.25 Å R-free 0.191
6Z4G A4V mutant of human SOD1 bound with ebselen in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 ACT ACETATE ION × 2 9JT N-phenyl-2-selanylbenzamide × 2 SO4 SULFATE ION × 4 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.45 Å R-free 0.193
6Z4H A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 LQW ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.6M ammonium sulphate
Resolution 1.95 Å R-free 0.242
6Z4I A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain FFF 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 ACT ACETATE ION × 2 SO4 SULFATE ION × 2 Q85 ~{N}-[(4-methoxyphenyl)methyl]-2-selanyl-benzamide × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.60 Å R-free 0.217
6Z4J A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 5 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 Q7W ~{N}-[(3-chlorophenyl)methyl]-2-selanyl-benzamide × 2 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.5M ammonium sulphate
Resolution 1.55 Å R-free 0.208
6Z4K A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 6 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V Q7N ~{N}-[(3-methoxyphenyl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 4 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.45 Å R-free 0.209
6Z4L A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V Q8H ~{N}-(pyridin-3-ylmethyl)-2-selanyl-benzamide × 2 ZN ZINC ION × 4 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.60 Å R-free 0.208
6Z4M A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 10 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V Q8E ~{N}-[(6-methoxypyridin-3-yl)methyl]-2-selanyl-benzamide × 2 ZN ZINC ION × 4 CL CHLORIDE ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.55 Å R-free 0.208
6Z4O A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 1 in P21 space group Deposited 2020-05-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain AAA 2–154（153 aa）
Chain BBB 2–154（153 aa）
Mutation：A4V Mutation：A4V ZN ZINC ION × 4 Q7T ~{N}-(phenylmethyl)-2-selanyl-benzamide × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.40 Å R-free 0.232
7FB6 C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–154（154 aa）
Mutation：C57D/C146D Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 1 CU COPPER (II) ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.2M MgCl2, 22% (w/v) PEG 3350
Resolution 1.80 Å R-free 0.213
7FB6 C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 1–154（154 aa）
Mutation：C57D/C146D Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 1 CU COPPER (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.2M MgCl2, 22% (w/v) PEG 3350
Resolution 1.80 Å R-free 0.213
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain I 1–154（154 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain D 1–154（154 aa）
Chain E 1–154（154 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Chain G 1–154（154 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain H 1–154（154 aa）
Chain L 1–154（154 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain J 1–154（154 aa）
Chain K 1–154（154 aa）
Not recorded ZN ZINC ION × 2 CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain M 1–154（154 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7FB9 Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) Deposited 2021-07-08 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain N 1–154（154 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；287.15 K；0.1M sodium acetate-HCl (pH 4.5), 21% (w/v) PEG 3350
Resolution 2.70 Å R-free 0.247
7NXX Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). Deposited 2021-03-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；273 K；0.1 M Hepes,1.5 M Lithium sulphate, pH 7.5
Resolution 2.19 Å R-free 0.245
7T8E G93A mutant of human SOD1 in P21 space group Deposited 2021-12-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 4 ACT ACETATE ION × 1 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.40 Å R-free 0.229
7T8F G93A mutant of human SOD1 bound with Ebselen in P21 space group Deposited 2021-12-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 4 ACT ACETATE ION × 1 9JT N-phenyl-2-selanylbenzamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.40 Å R-free 0.225
7T8G G93A mutant of human SOD1 bound with MR6-8-2 in P21 space group Deposited 2021-12-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 4 Q8H ~{N}-(pyridin-3-ylmethyl)-2-selanyl-benzamide × 2 ACT ACETATE ION × 1 SO4 SULFATE ION × 2 SE SELENIUM ATOM × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.35 Å R-free 0.202
7T8H G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group Deposited 2021-12-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain F 2–154（153 aa）
Mutation：G93A Mutation：G93A ZN ZINC ION × 4 ACT ACETATE ION × 1 Q8E ~{N}-[(6-methoxypyridin-3-yl)methyl]-2-selanyl-benzamide × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.7；292 K；100mM NaOAc pH 4.7, 150mM NaCl, 2.7M ammonium sulphate
Resolution 1.50 Å R-free 0.224
7VZF Cryo-EM structure of amyloid fibril formed by full-length human SOD1 Deposited 2021-11-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.95 Å
7XX3 Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) Deposited 2022-05-28 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 4 I2G (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate (pH = 6.5)
Resolution 1.90 Å R-free 0.230
7XX3 Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) Deposited 2022-05-28 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 1 I2G (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate (pH = 6.5)
Resolution 1.90 Å R-free 0.230
7XX3 Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) Deposited 2022-05-28 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded ZN ZINC ION × 2 DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate (pH = 6.5)
Resolution 1.90 Å R-free 0.230
7XX3 Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) Deposited 2022-05-28 Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Chain G 1–154（154 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate (pH = 6.5)
Resolution 1.90 Å R-free 0.230
7XX3 Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) Deposited 2022-05-28 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 1 I2G (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate (pH = 6.5)
Resolution 1.90 Å R-free 0.230
8CCX Human SOD1 in complex with S-XL6 cross-linker Deposited 2023-01-27 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain F 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 4 SO4 SULFATE ION × 2 UDI butane-1,4-dithiol × 1 DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.75；293 K；2.5M ammonium sulphate, 150mM NaCl, sodium acetate pH 4.75
Resolution 1.67 Å R-free 0.233
8GSQ Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. Deposited 2022-09-06 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；Sodium Citrate
Resolution 2.10 Å R-free 0.208
8GSQ Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. Deposited 2022-09-06 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；Sodium Citrate
Resolution 2.10 Å R-free 0.208
8GSQ Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. Deposited 2022-09-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；Sodium Citrate
Resolution 2.10 Å R-free 0.208
8GSQ Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. Deposited 2022-09-06 Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；Sodium Citrate
Resolution 2.10 Å R-free 0.208
8IHU Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation G85R Deposited 2023-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.97 Å
8IHV Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation H46R Deposited 2023-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.11 Å
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 10 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain Y 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 11 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 12 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 7 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain L 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 8 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain N 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K33 SOD1 and Nanobody1 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 9 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain P 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；291 K；0.2 M Ammonium acetate, 0.1 M Tris pH 8.5, 25% w/v Polyethylene glycol 3,350
Resolution 2.13 Å R-free 0.265
8K3A SOD1 and Nanobody2 complex Deposited 2023-07-14 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.1 M Magnesium chloride, 0.1 M Sodium, citrate pH 5, 15%(w/v) PEG 4000
Resolution 2.74 Å R-free 0.256
8K3L SOD1 and Nanobody3 complex Deposited 2023-07-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Not recorded CU COPPER (II) ION × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate trihydrate pH 4.6, 30% w/v Polyethylene, glycol monomethyl ether 2,000
Resolution 2.30 Å R-free 0.235
8K3L SOD1 and Nanobody3 complex Deposited 2023-07-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–154（153 aa）
Not recorded CU COPPER (II) ION × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate trihydrate pH 4.6, 30% w/v Polyethylene, glycol monomethyl ether 2,000
Resolution 2.30 Å R-free 0.235
8K3L SOD1 and Nanobody3 complex Deposited 2023-07-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–154（153 aa）
Not recorded CU COPPER (II) ION × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate trihydrate pH 4.6, 30% w/v Polyethylene, glycol monomethyl ether 2,000
Resolution 2.30 Å R-free 0.235
8K3L SOD1 and Nanobody3 complex Deposited 2023-07-16 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 2–154（153 aa）
Not recorded CU COPPER (II) ION × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate trihydrate pH 4.6, 30% w/v Polyethylene, glycol monomethyl ether 2,000
Resolution 2.30 Å R-free 0.235
8Q6M Human SOD1 low dose data collecton Deposited 2023-08-14 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ACT ACETATE ION × 1 ZN ZINC ION × 2 CU COPPER (II) ION × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.75；293 K；2.5 M Ammonium sulphate, Acetate buffer pH 4.75
Resolution 1.77 Å R-free 0.251
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain H 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain L 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain P 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAF SOD1, Nanobody1 and Nanobody2 complex Deposited 2024-02-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain T 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；5% (v/v) Isopropanol, 2.0 M Ammonium sulfate
Resolution 3.28 Å R-free 0.249
8YAT SOD1, Nanobody1, Nanobody2 and Nanobody3 complex Deposited 2024-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2M Ammonium sulfate, 0.1M HEPES pH8.0, 20%w/v Polyethylene glycol 3350
Resolution 3.94 Å R-free 0.368
8YAT SOD1, Nanobody1, Nanobody2 and Nanobody3 complex Deposited 2024-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain E 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2M Ammonium sulfate, 0.1M HEPES pH8.0, 20%w/v Polyethylene glycol 3350
Resolution 3.94 Å R-free 0.368
8YAT SOD1, Nanobody1, Nanobody2 and Nanobody3 complex Deposited 2024-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain I 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2M Ammonium sulfate, 0.1M HEPES pH8.0, 20%w/v Polyethylene glycol 3350
Resolution 3.94 Å R-free 0.368
8YAT SOD1, Nanobody1, Nanobody2 and Nanobody3 complex Deposited 2024-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain M 2–154（153 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2M Ammonium sulfate, 0.1M HEPES pH8.0, 20%w/v Polyethylene glycol 3350
Resolution 3.94 Å R-free 0.368
8YD3 Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol Deposited 2024-02-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 A1LYN (2S)-decane-1,2,10-triol × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate
Resolution 1.96 Å R-free 0.211
8YD3 Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol Deposited 2024-02-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 2 A1LYN (2S)-decane-1,2,10-triol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate
Resolution 1.96 Å R-free 0.211
8YD3 Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol Deposited 2024-02-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain F 1–154（154 aa）
Not recorded ZN ZINC ION × 2 GOL GLYCEROL × 1 A1LYN (2S)-decane-1,2,10-triol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate
Resolution 1.96 Å R-free 0.211
8YD3 Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol Deposited 2024-02-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded ZN ZINC ION × 1 A1LYN (2S)-decane-1,2,10-triol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate
Resolution 1.96 Å R-free 0.211
8YD3 Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol Deposited 2024-02-19 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded ZN ZINC ION × 2 A1LYN (2S)-decane-1,2,10-triol × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；1.3 M Sodium citrate
Resolution 1.96 Å R-free 0.211
9IYD Cryo-EM structure of an amyloid fibril formed by SOD1 mutant - G93A Deposited 2024-07-30 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Mutation：G94A Mutation：G94A Mutation：G94A No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.09 Å
9IYJ Cryo-EM structure of an amyloid fibril formed by SOD1 mutant - D101N Deposited 2024-07-30 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Chain C 2–154（153 aa）
Mutation：D102N Mutation：D102N Mutation：D102N No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.92 Å
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 3 ACT ACETATE ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 ACT ACETATE ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 1–154（154 aa）
Chain L 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 1–154（154 aa）
Chain F 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 1–154（154 aa）
Chain H 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9IYK Crystal structure of hSOD1 in C121 space group Deposited 2024-07-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 1–154（154 aa）
Chain J 1–154（154 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate
Resolution 2.34 Å R-free 0.263
9JBO Cryo-EM structure of human SOD1 (WT) amyloid filament Deposited 2024-08-27 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.39 Å
9JBP Cryo-EM structure of human SOD1 (C6A/C111A) amyloid filament Deposited 2024-08-27 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Chain D 1–154（154 aa）
Chain E 1–154（154 aa）
Chain F 1–154（154 aa）
Mutation：C6A,C111A Mutation：C6A,C111A Mutation：C6A,C111A Mutation：C6A,C111A Mutation：C6A,C111A Mutation：C6A,C111A No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.18 Å
9LI1 Cryo-EM structure of human SOD1 (G93A) amyloid filament Deposited 2025-01-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 1–154（154 aa）
Chain B 1–154（154 aa）
Chain C 1–154（154 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.74 Å
9MIL Superoxide dismutase residues 28-39 with G37R mutation Deposited 2024-12-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 10 PDB declaration: decameric
Chain A 29–40（12 aa）
Chain B 29–40（12 aa）
Chain C 29–40（12 aa）
Chain D 29–40（12 aa）
Chain E 29–40（12 aa）
Chain F 29–40（12 aa）
Chain G 29–40（12 aa）
Chain H 29–40（12 aa）
Chain I 29–40（12 aa）
Chain J 29–40（12 aa）
Not recorded SO4 SULFATE ION × 5 PG4 TETRAETHYLENE GLYCOL × 2 PEG DI(HYDROXYETHYL)ETHER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；298 K；1.0 M Ammonium sulfate, 0.1 M BIS-TRIS pH 5.5, 1% w/v Polyethylene glycol 3,350
Resolution 2.50 Å R-free 0.263
9XJ0 Crystal structure of SOD1 by serial synchrotron crystallography Deposited 2025-11-04 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate, PVP-K15
Resolution 2.30 Å R-free 0.210
9XJI Cryogenic structure of SOD1, determined as the SSX counterpart Deposited 2025-11-04 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 2–154（153 aa）
Chain B 2–154（153 aa）
Not recorded CU COPPER (II) ION × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Ammonium sulfate, sodium acetate, PVP-K15
Resolution 2.37 Å R-free 0.231

153 other PDB entries and 371 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name SODC_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–154； UniProt 1–154 Author chain B； PDBConstruct 1–154； UniProt 1–154 Author chain C； PDBConstruct 1–154； UniProt 1–154 Author chain D； PDBConstruct 1–154； UniProt 1–154 Author chain E； PDBConstruct 1–154； UniProt 1–154 Author chain F； PDBConstruct 1–154； UniProt 1–154 Author chain G； PDBConstruct 1–154； UniProt 1–154 Author chain H； PDBConstruct 1–154； UniProt 1–154 Author chain I； PDBConstruct 1–154； UniProt 1–154 Author chain J； PDBConstruct 1–154； UniProt 1–154

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 6a9o

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 6a9o
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2. Structure Basics 2. Structure Basics

Entry ID entry_id6a9o
Deposition date deposition_date2018-07-14
Structure title titleRational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis
Keywords keywordsdismutase, dimer, oxidation, OXIDOREDUCTASE-INHIBITOR complex; OXIDOREDUCTASE/INHIBITOR
Experimental Method methodX-RAY DIFFRACTION
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier42.70 Å
Radius of gyration Rg (electron density) rg_electron42.39 Å
Forward intensity I(0) i0424389000.00
Molecular weight molecular_weight157420.0 kDa
Excluded volume excluded_volume192350 ų
Envelope volume envelope_volume273580 ų
Hydration-shell volume shell_volume54494 ų
Envelope diameter envelope_diameter149.6 Å
Shell Rg shell_rg47.07 Å
Envelope Rg envelope_rg41.34 Å
Shape Rg shape_rg42.41 Å
Total Rg total_rg42.54 Å
Total atoms total_atoms11010
Residues n_residues1512
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax141.1 Å
Rg (real space) rg_real42.68 Å
Rg uncertainty (real space) rg_real_error1.24 Å
I(0) (real space) i0_real4.2440e+08
I(0) uncertainty (real space) i0_real_error7.3640e+06
Rg (reciprocal space) rg_reciprocal42.70 Å
I(0) (reciprocal space) i0_reciprocal424400000.0000
Solution quality estimate total_estimate0.6704
Solution quality rating solution_quality REASONABLE a REASONABLE solution
P(r) peaks n_peaks1
Primary peak position r_peak_primary53.4 Å
Skewness Skewness skewness0.234
Kurtosis Kurtosis kurtosis-0.509
Angular range angular_range— – 0.1850 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha17500000.0000
Real-space data points n_real_points38
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.917; Stabil: 1.000; Sysdev: 0.016; Positv: 1.000; Valcen: 0.996; Smooth: 0.914
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (7)

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7. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (10 domains)

Domain ID domain_idd6a9oa_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9ob_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9oc_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9od_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9oe_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9of_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9og_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9oh_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9oi_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
Domain ID domain_idd6a9oj_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.8 — Cu,Zn superoxide dismutase-like
Family Family familyb.1.8.1 — Cu,Zn superoxide dismutase-like
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8. Citations (1)

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9. Files and Curves (10)