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6mhq

Structure of connexin-46 intercellular gap junction channel at 3.4 angstrom resolution by cryoEM

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Gap junction alpha-3 protein, connexin-46

OrganismNot specified

UniProt Q9TU17

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 12 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
6mhq 7jkc 7jmd 7jn0 7jn1 9z7p 9z81 9z8f 9z8m 9z9g 9z9s 9z9x

13 assemblies; showing the first 12

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name CXA3_SHEEP
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–348； UniProt 1–348 Author chain B； PDBConstruct 1–348； UniProt 1–348 Author chain C； PDBConstruct 1–348； UniProt 1–348 Author chain D； PDBConstruct 1–348； UniProt 1–348 Author chain E； PDBConstruct 1–348； UniProt 1–348 Author chain F； PDBConstruct 1–348； UniProt 1–348 Author chain G； PDBConstruct 1–348； UniProt 1–348 Author chain H； PDBConstruct 1–348； UniProt 1–348 Author chain I； PDBConstruct 1–348； UniProt 1–348 Author chain J； PDBConstruct 1–348； UniProt 1–348 Author chain K； PDBConstruct 1–348； UniProt 1–348 Author chain L； PDBConstruct 1–348； UniProt 1–348

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6mhq
Deposition date deposition_date2018-09-18
Structure title titleStructure of connexin-46 intercellular gap junction channel at 3.4 angstrom resolution by cryoEM
Keywords keywordsion channel, gap junction, cell communication, connexin, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6mhq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6mhq__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6mhq__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）43.28 Å
Rg (electron density)44.84 Å
Total Rg44.91 Å
Atom count32640
Residues2124
Excluded volume315800 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6mhq__assembly_1__model_1 dodecameric （12） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)