← Back to search
6nzw

LRRC8A-DCPIB in MSP1E3D1 nanodisc constricted state

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Volume-regulated anion channel subunit LRRC8A

Mus musculus

UniProt Q80WG5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 18 4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acid × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
6fnw

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
6g8z 6g9l 6g9o 6nzw 6nzz 6o00 7m17 7m19

8 assemblies

Heteromeric or nucleic-acid complex
7p5v 7p5w 7p5y 7p60 7p6k 8b41 8b42 8dr8 8dra 8dre 8drk 8drn

27 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name LRC8A_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–810； UniProt 1–810 Author chain B； PDBConstruct 1–810； UniProt 1–810 Author chain C； PDBConstruct 1–810； UniProt 1–810 Author chain D； PDBConstruct 1–810； UniProt 1–810 Author chain E； PDBConstruct 1–810； UniProt 1–810 Author chain F； PDBConstruct 1–810； UniProt 1–810

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6nzw
Deposition date deposition_date2019-02-14
Structure title titleLRRC8A-DCPIB in MSP1E3D1 nanodisc constricted state
Keywords keywordsIon channel, volume-regulation, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6nzw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6nzw__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6nzw__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）42.61 Å
Rg (electron density)40.74 Å
Total Rg41.31 Å
Atom count32060
Residues1878
Excluded volume291280 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6nzw__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▶

7. Citations (1)