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6q0k

Structure of a MAPK pathway complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Serine/threonine-protein kinase B-raf

Homo sapiens

UniProt P15056

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 14-3-3 protein zeta/delta × 2 （P63104） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2fb8 2fb8 2l05 3c4c 3c4c 3d4q 3d4q 3idp 3idp 3ii5 3ii5 3ppj

104 assemblies; showing the first 12

Homodimer
1uwh 1uwj 3ii5 3ny5 3ny5 3ny5 3q96 4dbn 4e26 4ehe 4ehg 4fc0

43 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4mne 4mne 5vyk 6nyb 6pp9 6q0j 6q0k 6q0t 6u2g 6u2h 6uan 6v2w

44 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name BRAF_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 28–793； UniProt 1–766 Author chain B； PDBConstruct 28–793； UniProt 1–766

14-3-3 protein zeta/delta

OrganismNot specified

UniProt P63104

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Serine/threonine-protein kinase B-raf × 2 （P15056） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
3rdh 3rdh 6fn9 6fna 6fnb 6fnc

6 assemblies

Homotetramer
3rdh

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1ib1 1ib1 2c1j 2c1n 2c1n 2o02 2wh0 2wh0 3cu8 3nkx 4bg6 4fj3

82 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name 1433Z_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain X； PDBConstruct 1–245； UniProt 1–245 Author chain Y； PDBConstruct 1–245； UniProt 1–245

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6q0k
Deposition date deposition_date2019-08-01
Structure title titleStructure of a MAPK pathway complex
Keywords keywordsTRANSFERASE, SIGNALING PROTEIN-Transferase complex; SIGNALING PROTEIN/Transferase
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6q0k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6q0k__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6q0k__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）33.98 Å
Rg (electron density)33.32 Å
Total Rg33.93 Å
Atom count5079
Residues1022
Excluded volume81985 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6q0k__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)