7n85

Inner ring spoke from the isolated yeast NPC

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Nucleoporin NUP170

OrganismNot specified

UniProt P38181

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU170_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 0; PDBConstruct 1–1502; UniProt 1–1502 Author chain Y; PDBConstruct 1–1502; UniProt 1–1502

Nucleoporin NUP157

OrganismNot specified

UniProt P40064

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU157_YEAST
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 1; PDBConstruct 1–1391; UniProt 1–1391 Author chain Z; PDBConstruct 1–1391; UniProt 1–1391

Nucleoporin NSP1

OrganismNot specified

UniProt P14907

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NSP1_YEAST
Isoform —
PDB entities 4
Chains and sequence ranges Author chain A; PDBConstruct 1–823; UniProt 1–823 Author chain D; PDBConstruct 1–823; UniProt 1–823 Author chain G; PDBConstruct 1–823; UniProt 1–823 Author chain J; PDBConstruct 1–823; UniProt 1–823

Nucleoporin NUP57

OrganismNot specified

UniProt P48837

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP57_YEAST
Isoform —
PDB entities 5
Chains and sequence ranges Author chain B; PDBConstruct 1–541; UniProt 1–541 Author chain E; PDBConstruct 1–541; UniProt 1–541 Author chain H; PDBConstruct 1–541; UniProt 1–541 Author chain K; PDBConstruct 1–541; UniProt 1–541

Nucleoporin NUP49/NSP49

OrganismNot specified

UniProt Q02199

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP49_YEAST
Isoform —
PDB entities 6
Chains and sequence ranges Author chain C; PDBConstruct 1–472; UniProt 1–472 Author chain F; PDBConstruct 1–472; UniProt 1–472 Author chain I; PDBConstruct 1–472; UniProt 1–472 Author chain L; PDBConstruct 1–472; UniProt 1–472

Nucleoporin NUP192

OrganismNot specified

UniProt P47054

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU192_YEAST
Isoform —
PDB entities 7
Chains and sequence ranges Author chain M; PDBConstruct 1–1683; UniProt 1–1683 Author chain O; PDBConstruct 1–1683; UniProt 1–1683

Nucleoporin NUP188

OrganismNot specified

UniProt P52593

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU188_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain N; PDBConstruct 1–1655; UniProt 1–1655 Author chain P; PDBConstruct 1–1655; UniProt 1–1655

Nucleoporin NIC96

OrganismNot specified

UniProt P34077

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NUP53 × 16 (Q03790) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NUP53 × 2 (Q03790) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NIC96_YEAST
Isoform —
PDB entities 9
Chains and sequence ranges Author chain Q; PDBConstruct 1–839; UniProt 1–839 Author chain R; PDBConstruct 1–839; UniProt 1–839 Author chain S; PDBConstruct 1–839; UniProt 1–839 Author chain T; PDBConstruct 1–839; UniProt 1–839

Nucleoporin NUP53

OrganismNot specified

UniProt Q03790

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin ASM4 × 16 (Q05166) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin ASM4 × 2 (Q05166) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP53_YEAST
Isoform —
PDB entities 10
Chains and sequence ranges Author chain U; PDBConstruct 1–475; UniProt 1–475 Author chain W; PDBConstruct 1–475; UniProt 1–475

Nucleoporin ASM4

OrganismNot specified

UniProt Q05166

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 240 Nucleoporin NUP170 × 16 (P38181) Nucleoporin NUP157 × 16 (P40064) Unknown connectors × 16 Nucleoporin NSP1 × 32 (P14907) Nucleoporin NUP57 × 32 (P48837) Nucleoporin NUP49/NSP49 × 32 (Q02199) Nucleoporin NUP192 × 16 (P47054) Nucleoporin NUP188 × 16 (P52593) Nucleoporin NIC96 × 32 (P34077) Nucleoporin NUP53 × 16 (Q03790) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 Nucleoporin NUP170 × 2 (P38181) Nucleoporin NUP157 × 2 (P40064) Unknown connectors × 2 Nucleoporin NSP1 × 4 (P14907) Nucleoporin NUP57 × 4 (P48837) Nucleoporin NUP49/NSP49 × 4 (Q02199) Nucleoporin NUP192 × 2 (P47054) Nucleoporin NUP188 × 2 (P52593) Nucleoporin NIC96 × 4 (P34077) Nucleoporin NUP53 × 2 (Q03790) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP59_YEAST
Isoform —
PDB entities 11
Chains and sequence ranges Author chain V; PDBConstruct 1–528; UniProt 1–528 Author chain X; PDBConstruct 1–528; UniProt 1–528

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7n85
Deposition date deposition_date2021-06-13
Structure title titleInner ring spoke from the isolated yeast NPC
Keywords keywordsnuclear pore complex, inner ring, spoke, TRANSLOCASE; TRANSLOCASE
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7n85__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7n85__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7n85__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)326.30 Å
Total Rg326.50 Å
Atom count984936
Residues124672
Excluded volume17679000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7n85__assembly_1__model_1 240-meric (240) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7n85__assembly_2__model_1 30-meric (30) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 7n85__assembly_3__model_1 30-meric (30) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (11)

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7. Citations (1)