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7woo

Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Nucleoporin NIC96

OrganismNot specified

UniProt P34077

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2qx5 2qx5 2rfo 2rfo

4 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6x07 7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

10 assemblies

View Construct and Data Evidence
UniProt name NIC96_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–839； UniProt 1–839 Author chain Z； PDBConstruct 1–839； UniProt 1–839

Nucleoporin NUP157

OrganismNot specified

UniProt P40064

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4mhc

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

9 assemblies

View Construct and Data Evidence
UniProt name NU157_YEAST
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–1391； UniProt 1–1391

Nucleoporin NUP170

OrganismNot specified

UniProt P38181

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3i5p 3i5q 3i5q

3 assemblies

Homodimer
3i5q

1 assemblies

Homotetramer
3i5q

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

9 assemblies

View Construct and Data Evidence
UniProt name NU170_YEAST
Isoform —
PDB entities 3
Chains and sequence ranges Author chain D； PDBConstruct 1–1502； UniProt 1–1502

Nucleoporin NUP188

OrganismNot specified

UniProt P52593

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
7wo9

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n84 7n84 7n84 7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

12 assemblies

View Construct and Data Evidence
UniProt name NU188_YEAST
Isoform —
PDB entities 4
Chains and sequence ranges Author chain E； PDBConstruct 1–1655； UniProt 1–1655

Nucleoporin NUP192

OrganismNot specified

UniProt P47054

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4ifq

1 assemblies

Homodimer
4ifq

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

9 assemblies

View Construct and Data Evidence
UniProt name NU192_YEAST
Isoform —
PDB entities 5
Chains and sequence ranges Author chain F； PDBConstruct 1–1683； UniProt 1–1683

Nucleoporin NUP49/NSP49

OrganismNot specified

UniProt Q02199

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP57 × 2 （P48837） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

9 assemblies

View Construct and Data Evidence
UniProt name NUP49_YEAST
Isoform —
PDB entities 6
Chains and sequence ranges Author chain G； PDBConstruct 1–472； UniProt 1–472 Author chain J； PDBConstruct 1–472； UniProt 1–472

Nucleoporin NUP57

OrganismNot specified

UniProt P48837

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NSP1 × 2 （P14907） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

9 assemblies

View Construct and Data Evidence
UniProt name NUP57_YEAST
Isoform —
PDB entities 7
Chains and sequence ranges Author chain H； PDBConstruct 1–541； UniProt 1–541 Author chain K； PDBConstruct 1–541； UniProt 1–541

Nucleoporin NSP1

OrganismNot specified

UniProt P14907

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Nucleoporin NIC96 × 2 （P34077） Nucleoporin NUP157 × 1 （P40064） Nucleoporin NUP170 × 1 （P38181） Nucleoporin NUP188 × 1 （P52593） Nucleoporin NUP192 × 1 （P47054） Nucleoporin NUP49/NSP49 × 2 （Q02199） Nucleoporin NUP57 × 2 （P48837） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1o6o 1o6o 1o6o 7n85 7n85 7n85 7n9f 7n9f 7n9f 7woo 7wot 8tj5

12 assemblies

View Construct and Data Evidence
UniProt name NSP1_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain I； PDBConstruct 1–823； UniProt 1–823 Author chain L； PDBConstruct 1–823； UniProt 1–823

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7woo
Deposition date deposition_date2022-01-22
Structure title titleCryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore complex
Keywords keywordsnuclear pore complex, inner ring, protomer, Saccharomyces cerevisiae, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7woo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7woo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7woo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）92.07 Å
Rg (electron density)93.25 Å
Total Rg93.22 Å
Atom count66949
Residues8644
Excluded volume1194600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7woo__assembly_1__model_1 dodecameric （12） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

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7. Citations (1)