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7nir

1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core

Method: ELECTRON MICROSCOPY Dmax: 140.7 Å Quality: REASONABLE
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Polymerase acidic protein

Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)

UniProt Q3HM39

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 4 RNA 2 PDB declaration: hexameric（6） Consistent with all polymer counts Chain A； UniProt 1–716 Not recorded RNA-directed RNA polymerase catalytic subunit × 1 （Q3HM40） Polymerase basic protein 2,Immunoglobulin G-binding protein A × 1 （Q3HM41,P38507） ;RNA (5'-R(P*GP*GP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3') ; × 1 Nanobody8191 core × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 7.5 cryo-EM vitrification conditions：Cryogen ETHANE Resolution 6.70 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7NIR Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
7NHA 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.91 Å
7NHC 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.87 Å
7NHX 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.23 Å
7NI0 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.32 Å
7NIK 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.20 Å
7NIL 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.01 Å
7NIS 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core Deposited 2021-02-13 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.96 Å
7NJ3 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core Deposited 2021-02-15 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.48 Å
7NJ4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.84 Å
7NJ5 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7NJ7 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.82 Å
7NK1 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.22 Å
7NK2 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.84 Å
7NK4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.32 Å
7NK6 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.72 Å
7NK8 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.34 Å
7NKA 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.07 Å
7NKC 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.46 Å
7NKI 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.67 Å
7NKR 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.60 Å
8R60 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide Deposited 2023-11-19 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.23 Å
8R65 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains Deposited 2023-11-20 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.23 Å
9RVE Structure of human 1918 influenza A polymerase heterotrimer in complex with 1918 NEP. Deposited 2025-07-08 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.53 Å
9RYC Structure of human 1918 influenza A polymerase heterotrimer in complex with WSN NEP. Deposited 2025-07-15 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–716（716 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.93 Å

24 other PDB entries and 24 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name PA_I18A0
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–716； UniProt 1–716

RNA-directed RNA polymerase catalytic subunit

Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)

UniProt Q3HM40

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 4 RNA 2 PDB declaration: hexameric（6） Consistent with all polymer counts Chain B； UniProt 1–757 Not recorded Polymerase acidic protein × 1 （Q3HM39） Polymerase basic protein 2,Immunoglobulin G-binding protein A × 1 （Q3HM41,P38507） ;RNA (5'-R(P*GP*GP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3') ; × 1 Nanobody8191 core × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 7.5 cryo-EM vitrification conditions：Cryogen ETHANE Resolution 6.70 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7NIR Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
7NHA 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.91 Å
7NHC 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.87 Å
7NHX 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.23 Å
7NI0 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.32 Å
7NIK 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.20 Å
7NIL 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.01 Å
7NIS 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core Deposited 2021-02-13 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.96 Å
7NJ3 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core Deposited 2021-02-15 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.48 Å
7NJ4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.84 Å
7NJ5 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7NJ7 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.82 Å
7NK1 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.22 Å
7NK2 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.84 Å
7NK4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.32 Å
7NK6 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.72 Å
7NK8 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.34 Å
7NKA 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.07 Å
7NKC 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.46 Å
7NKI 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.67 Å
7NKR 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.60 Å
8R60 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide Deposited 2023-11-19 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.23 Å
8R65 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains Deposited 2023-11-20 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.23 Å
9RVE Structure of human 1918 influenza A polymerase heterotrimer in complex with 1918 NEP. Deposited 2025-07-08 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.53 Å
9RYC Structure of human 1918 influenza A polymerase heterotrimer in complex with WSN NEP. Deposited 2025-07-15 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–757（757 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.93 Å

24 other PDB entries and 24 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name RDRP_I18A0
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–757； UniProt 1–757

Polymerase basic protein 2,Immunoglobulin G-binding protein A

Staphylococcus aureus

UniProt P38507

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 4 RNA 2 PDB declaration: hexameric（6） Consistent with all polymer counts Chain C； UniProt 158–271 Not recorded Polymerase acidic protein × 1 （Q3HM39） RNA-directed RNA polymerase catalytic subunit × 1 （Q3HM40） ;RNA (5'-R(P*GP*GP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3') ; × 1 Nanobody8191 core × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 7.5 cryo-EM vitrification conditions：Cryogen ETHANE Resolution 6.70 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7NIR Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1BDC STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, 10 STRUCTURES Deposited 1996-06-28 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；303 K
Resolution not provided
1BDD STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-06-28 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；303 K
Resolution not provided
1EDI STAPHYLOCOCCAL PROTEIN A E-DOMAIN (180), NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-10-07 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDJ STAPHYLOCOCCAL PROTEIN A E-DOMAIN (180), NMR, 20 STRUCTURES Deposited 1996-10-07 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN (180)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDK STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-07-22 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDL STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, 22 STRUCTURES Deposited 1996-07-22 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1LP1 Protein Z in complex with an in vitro selected affibody Deposited 2002-05-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 212–269（58 aa） Fragment：RESIDUES 2-58
Mutation：A1V, G29A SO4 SULFATE ION × 4 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；MgSO4, MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.30 Å R-free 0.256
1LP1 Protein Z in complex with an in vitro selected affibody Deposited 2002-05-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 212–269（58 aa） Fragment：RESIDUES 2-58
Mutation：A1V, G29A SO4 SULFATE ION × 8 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；MgSO4, MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.30 Å R-free 0.256
1Q2N REFINED Solution NMR structure of the Z domain of STAPHYLOCOCCAL PROTEIN A Deposited 2003-07-25 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–269（58 aa） Fragment：residues 212-269
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；303 K；Ionic strength (raw mmCIF value) 20 mM NH4OAc；Pressure 1
NMR sample composition 1mM Z domain U-15N,13C; 20mM NH4OAc buffer; 95% H2O, 5% D2O. | 95% H2O/5% D2O
Resolution not provided
1SS1 STAPHYLOCOCCAL PROTEIN A, B-DOMAIN, Y15W MUTANT, NMR, 25 STRUCTURES Deposited 2004-03-23 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Mutation：Y15W No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.5；298 K；Ionic strength (raw mmCIF value) 100 mM NaCl / 50 mM acetate；Pressure ambient
NMR sample composition 2mM sample, U-13C, U-15N; 50 mM D-acetate buffer, 100 mM NaCl, pH 5.5; 90% H2O, 10% D2O | 90% H20, 10% D20
Resolution not provided
2JWD protein A Deposited 2007-10-09 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 213–269（57 aa） Fragment：B domain
Mutation：Y15W No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition 20mM sodium acetate, 100mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2M5A Protein A binding by an engineered Affibody molecule Deposited 2013-02-19 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.6；298 K；Ionic strength (raw mmCIF value) 0.095；Pressure ambient
NMR sample composition 0.5 to 1 mM [U-99% 13C; U-99% 15N] Z domain, 25% molar excess mM ZpA963, 93% H2O/7% D2O | 93% H2O/7% D2O
NMR sample composition 0.5 to 1.0 mM [U-99% 13C; U-99% 15N] ZpA963, 25 5 molar excess mM Z domain, 93% H2O/7% D2O | 93% H2O/7% D2O
Resolution not provided
2SPZ STAPHYLOCOCCAL PROTEIN A, Z-DOMAIN, NMR, 10 STRUCTURES Deposited 1998-07-29 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–269（58 aa） Fragment：Z DOMAIN
Mutation：A1V, G29A No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；303 K；Ionic strength (raw mmCIF value) 10 MILLIMOLAR K2HPO4；Pressure 1
Resolution not provided
3MZW HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342 Deposited 2010-05-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 212–269（58 aa） Fragment：B 4 repeat domain residues 212-269
Mutation：A212V, Q220M, Q221R, F224Y, Y225W, L228A, H229L, E235N, E236Q, R238K, N239R, G240A, Q243R, K246Y NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；279 K；0.05M sodium chloride, 7.5% PEG3350, 0.1M ammonium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 279K
Resolution 2.90 Å R-free 0.278
4NPD High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature Deposited 2013-11-21 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded ZN ZINC ION × 2 SCN THIOCYANATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；298 K；Na Thiocyanate, PEG 3350, Glycerol, pH 7, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 0.90 Å R-free 0.130
4NPE High-resolution structure of C domain of staphylococcal protein A at room temperature Deposited 2013-11-21 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded ZN ZINC ION × 1 SCN THIOCYANATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；298 K；Na Thiocyanate, PEG 3350, Glycerol, pH 7, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 1.42 Å R-free 0.143
4NPF High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain Y 154–269（116 aa） Fragment：UNP residues 212-323
Mutation：W13F, W113F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；Ammonium Sulfate, MES, pH 6, vapor diffusion, sitting drop, temperature 298K
Resolution 1.49 Å R-free 0.185
4NPF High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain X 154–269（116 aa） Fragment：UNP residues 212-323
Mutation：W13F, W113F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；Ammonium Sulfate, MES, pH 6, vapor diffusion, sitting drop, temperature 298K
Resolution 1.49 Å R-free 0.185
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4ZMD C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-03 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；PEG 3350, sodium thiocyanate
Resolution 1.87 Å R-free 0.256
4ZMD C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-03 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；PEG 3350, sodium thiocyanate
Resolution 1.87 Å R-free 0.256
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
5CBN Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 218–269（52 aa） Fragment：B4 domain (UNP RESIDUES 218-269)
Mutation：E126A, N129A, E133C, G147A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 6.5；277 K；36% w/v PEG 2000, 0.2M magnesium chloride hexahydrate
Resolution 2.30 Å R-free 0.260
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain J 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 11 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain K 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 12 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain L 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5COC Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 213–267（55 aa） Fragment：B4 domain (UNP RESIDUES 213-267),N-terminal (UNP RESIDUES 5-78)
Mutation：G240A, K261C, L1005A, T1006A, Q1009C CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；298 K；10% w/v PEG 1000, 10% w/v PEG 8000
Resolution 2.67 Å R-free 0.259
5EWX Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-11-22 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–266（55 aa） Fragment：UNP RESIDUES 1-35, 219-266, 38-164
Mutation：A1212V, G1240A, E1258C, K1261A, L1262A, N40C, C54T, C97A, K162A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.5；277 K；1.84M Na/K Phosphate, pH 7.5
Resolution 2.60 Å R-free 0.253
5EWX Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-11-22 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain B 212–266（55 aa） Fragment：UNP RESIDUES 1-35, 219-266, 38-164
Mutation：A1212V, G1240A, E1258C, K1261A, L1262A, N40C, C54T, C97A, K162A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.5；277 K；1.84M Na/K Phosphate, pH 7.5
Resolution 2.60 Å R-free 0.253
5H75 Crystal structure of the MrsD-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 12 PDB declaration: dodecameric
Chain A 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain B 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain C 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain D 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Mutation：K182Q,G240A Mutation：K182Q,G240A Mutation：K182Q,G240A Mutation：K182Q,G240A FAD FLAVIN-ADENINE DINUCLEOTIDE × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；277 K；0.94M sodium citrate pH 5.5
Resolution 2.74 Å R-free 0.243
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain B 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain D 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain F 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain H 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain J 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain L 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H79 Crystal structure of a repeat protein with three Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 217–263（47 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain D 219–263（45 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain D 219–268（50 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 13.5%(w/v) PEG 1000
Resolution 2.70 Å R-free 0.278
5H79 Crystal structure of a repeat protein with three Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 217–263（47 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain C 219–263（45 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain C 219–268（50 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 13.5%(w/v) PEG 1000
Resolution 2.70 Å R-free 0.278
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain C 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain C 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain J 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain J 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain J 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 11 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain K 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain K 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain K 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 12 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain L 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain L 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain L 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain A 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain D 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain D 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain B 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain B 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain E 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain E 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain F 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain F 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain G 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain G 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain H 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain H 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain I 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain I 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7B Crystal structure of a repeat protein with five Protein A repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–263（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain A 219–263（45 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 27.3% PEG MME 2000
Resolution 3.10 Å R-free 0.315
5H7B Crystal structure of a repeat protein with five Protein A repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 215–263（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain B 219–263（45 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain B 219–267（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 27.3% PEG MME 2000
Resolution 3.10 Å R-free 0.315
5H7C Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–267（53 aa） Fragment：UNP RESIDUES 215-267,219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-267,219-267
Mutation：10 mutations Mutation：10 mutations No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；296 K；0.1M Tris pH 8.0, 33.75%(w/v) PEG MME 2000
Resolution 2.70 Å R-free 0.262
5H7C Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 215–267（53 aa） Fragment：UNP RESIDUES 215-267,219-267
Chain C 219–267（49 aa） Fragment：UNP RESIDUES 215-267,219-267
Mutation：10 mutations Mutation：10 mutations No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；296 K；0.1M Tris pH 8.0, 33.75%(w/v) PEG MME 2000
Resolution 2.70 Å R-free 0.262
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain A 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain B 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain C 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain D 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain I 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain J 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain M 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain N 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
5X3F Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain Deposited 2017-02-05 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain A 220–269（50 aa） Fragment：UNP RESIDUES 7-453,220-269
Mutation：N222V, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；296 K；91mM MES pH 5.5, 2.33M Na formate
Resolution 3.38 Å R-free 0.227
5XBY Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) Deposited 2017-03-21 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Chain B 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Mutation：G240A Mutation：G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；296 K；100mM Tris pH 8.5, 2.16M Sodium formate
Resolution 3.25 Å R-free 0.307
5XBY Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) Deposited 2017-03-21 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Chain D 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Mutation：G240A Mutation：G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；296 K；100mM Tris pH 8.5, 2.16M Sodium formate
Resolution 3.25 Å R-free 0.307
6KRV Crystal structure of mouse IgG2b Fc complexed with B domain of Protein A Deposited 2019-08-22 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；60% (v/v) Tacsimate (pH 7.0)
Resolution 3.30 Å R-free 0.250
6KRV Crystal structure of mouse IgG2b Fc complexed with B domain of Protein A Deposited 2019-08-22 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Other combination Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；60% (v/v) Tacsimate (pH 7.0)
Resolution 3.30 Å R-free 0.250
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 180 PDB declaration: 180-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 15 PDB declaration: pentadecameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 18 PDB declaration: octadecameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 240 PDB declaration: 240-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 20 PDB declaration: eicosameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 24 PDB declaration: 24-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 240 PDB declaration: 240-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 20 PDB declaration: eicosameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 24 PDB declaration: 24-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7NHA 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.91 Å
7NHC 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.87 Å
7NHX 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.23 Å
7NI0 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.32 Å
7NIK 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.20 Å
7NIL 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.01 Å
7NIS 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core Deposited 2021-02-13 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.96 Å
7NJ3 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core Deposited 2021-02-15 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.48 Å
7NJ4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.84 Å
7NJ5 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7NJ7 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.82 Å
7NK1 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.22 Å
7NK2 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.84 Å
8CPL YZw2 a scaffold for cryo-EM of small proteins of interest Deposited 2023-03-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 220–269（50 aa）
Chain B 220–269（50 aa）
Chain C 220–269（50 aa）
Chain D 220–269（50 aa）
Not recorded PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；16.6% w/v PEG3350, 0.2M NaF and 0.1M Bis-Tris Propane pH 5.5
Resolution 1.60 Å R-free 0.210
8DA3 Coevolved affibody-Z domain pair LL1.c1 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, L17F, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 1 MLI MALONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；295 K；2.4 M Ammonium Sulfate 0.1 M bicine pH 9.0 Cryoprotected with sodium malonate
Resolution 1.06 Å R-free 0.168
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA5 Coevolved affibody-Z domain pair LL1.c4 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 212–269（58 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.3 M AmmPO4, 100 mM Tris pH 8.5 cryoprotected with 30% glycerol
Resolution 1.00 Å R-free 0.191
8DA5 Coevolved affibody-Z domain pair LL1.c4 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 212–269（58 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.3 M AmmPO4, 100 mM Tris pH 8.5 cryoprotected with 30% glycerol
Resolution 1.00 Å R-free 0.191
8DA6 Coevolved affibody-Z domain pair LL1.c5 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；295 K；2.4 M ammonium Sulfate 0.1 M citric acid pH 5.0 cryoprotected with sodium malonate
Resolution 1.50 Å R-free 0.251
8DA6 Coevolved affibody-Z domain pair LL1.c5 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9F, F13I, G29A, I31F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；295 K；2.4 M ammonium Sulfate 0.1 M citric acid pH 5.0 cryoprotected with sodium malonate
Resolution 1.50 Å R-free 0.251
8DA7 Coevolved affibody-Z domain pair LL1.c6 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.5 M AmmSO4, 100 mM tris pH 8.5 cryoprotected with Na malonate
Resolution 1.02 Å R-free 0.183
8DA8 Coevolved affibody-Z domain pair LL2.c1 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L F13V, G29A, I31F GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.5 M ammonium sulfate 100 mM HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.29 Å R-free 0.235
8DA9 Coevolved affibody-Z domain pair LL2.c3 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.4 M Ammonium sulfate 0.1M HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.35 Å R-free 0.198
8DA9 Coevolved affibody-Z domain pair LL2.c3 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.4 M Ammonium sulfate 0.1M HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.35 Å R-free 0.198
8DAA Coevolved affibody-Z domain pair LL2.c7 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；3.0 M Ammonium sulfate, 100 mM HEPES pH 7.0 cryoprotected with sodium malonate
Resolution 1.75 Å R-free 0.298
8DAA Coevolved affibody-Z domain pair LL2.c7 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；3.0 M Ammonium sulfate, 100 mM HEPES pH 7.0 cryoprotected with sodium malonate
Resolution 1.75 Å R-free 0.298
8DAB Coevolved affibody-Z domain pair LL2.c17 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9V, G29A, I31V Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；295 K；2.3 M Amm2HPO4, 100 mM Tris pH 8.2 cryoprotected in 30% glycerol
Resolution 1.13 Å R-free 0.200
8DAC Coevolved affibody-Z domain pair LL2.c22 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9I, F13V, L17F, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；295 K；2.5 M AmmSO4, 100 mM Tris pH 8.2 Cryoprotected with 30% glycerol
Resolution 1.19 Å R-free 0.196
8JXR Structure of nanobody-bound DRD1_LSD complex Deposited 2023-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Mutation：E360Q,K363A,D364F,T367I,R368L 7LD (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.57 Å
8JXS Structure of nanobody-bound DRD1_PF-6142 complex Deposited 2023-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Mutation：E360Q,K363A,D364F,T367I,R368L,D404E,A405H V6X 4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
8R2P YZwIdeal x16 a scaffold for cryo-EM of small proteins of interest crystallizing in space group 19 (P 21 21 21) Deposited 2023-11-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 218–269（52 aa）
Chain B 218–269（52 aa）
Chain C 218–269（52 aa）
Chain D 218–269（52 aa）
Mutation：G487A Mutation：G487A Mutation：G487A Mutation：G487A PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50% w/v PEG200, 0.2M MgCl2 and 0.1M Sodium Cacodylate buffer pH 6.5
Resolution 2.22 Å R-free 0.230
9QU4 Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2 Deposited 2025-04-10 Different construct Different oligomeric state Different ligand/ion Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 159–321（163 aa）
Not recorded CHT CHOLINE ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.39 Å
9W3K GPR151-Legobody complex Deposited 2025-07-29 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.08 Å

66 other PDB entries and 127 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name SPA_STAAU
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 784–897； UniProt 158–271

Polymerase basic protein 2,Immunoglobulin G-binding protein A

Staphylococcus aureus

UniProt Q3HM41

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 4 RNA 2 PDB declaration: hexameric（6） Consistent with all polymer counts Chain C； UniProt 1–759 Not recorded Polymerase acidic protein × 1 （Q3HM39） RNA-directed RNA polymerase catalytic subunit × 1 （Q3HM40） ;RNA (5'-R(P*GP*GP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3') ; × 1 Nanobody8191 core × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 7.5 cryo-EM vitrification conditions：Cryogen ETHANE Resolution 6.70 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7NIR Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
7NHA 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.91 Å
7NHC 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) Deposited 2021-02-10 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.87 Å
7NHX 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.23 Å
7NI0 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) Deposited 2021-02-11 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.32 Å
7NIK 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.20 Å
7NIL 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core Deposited 2021-02-12 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.01 Å
7NIS 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core Deposited 2021-02-13 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.96 Å
7NJ3 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core Deposited 2021-02-15 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.48 Å
7NJ4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.84 Å
7NJ5 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7NJ7 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core Deposited 2021-02-16 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.82 Å
7NK1 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.22 Å
7NK2 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core Deposited 2021-02-17 Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.84 Å
7NK4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.32 Å
7NK6 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.72 Å
7NK8 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.34 Å
7NKA 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.07 Å
7NKC 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 Deposited 2021-02-17 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.46 Å
7NKI 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.67 Å
7NKR 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 Deposited 2021-02-18 Different oligomeric state Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.60 Å
8R60 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide Deposited 2023-11-19 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.23 Å
8R65 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains Deposited 2023-11-20 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.23 Å
9RVE Structure of human 1918 influenza A polymerase heterotrimer in complex with 1918 NEP. Deposited 2025-07-08 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.53 Å
9RYC Structure of human 1918 influenza A polymerase heterotrimer in complex with WSN NEP. Deposited 2025-07-15 Different oligomeric state Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 1–759（759 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.93 Å

24 other PDB entries and 24 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name PB2_I18A0
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–759； UniProt 1–759

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 7nir

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 7nir
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2. Structure Basics 2. Structure Basics

Entry ID entry_id7nir
Deposition date deposition_date2021-02-13
Structure title title1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core
Keywords keywordsInfluenza, RNA polymerase, H1N1, 1918, VIRAL PROTEIN, nanobody; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier39.38 Å
Radius of gyration Rg (electron density) rg_electron39.18 Å
Forward intensity I(0) i0732297000.00
Molecular weight molecular_weight213310.0 kDa
Excluded volume excluded_volume263820 ų
Envelope volume envelope_volume343020 ų
Hydration-shell volume shell_volume71463 ų
Envelope diameter envelope_diameter150.3 Å
Shell Rg shell_rg45.74 Å
Envelope Rg envelope_rg39.25 Å
Shape Rg shape_rg39.21 Å
Total Rg total_rg39.43 Å
Total atoms total_atoms28796
Residues n_residues1819
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax140.7 Å
Rg (real space) rg_real39.39 Å
Rg uncertainty (real space) rg_real_error1.36 Å
I(0) (real space) i0_real7.3230e+08
I(0) uncertainty (real space) i0_real_error1.2870e+07
Rg (reciprocal space) rg_reciprocal39.39 Å
I(0) (reciprocal space) i0_reciprocal732300000.0000
Solution quality estimate total_estimate0.6107
Solution quality rating solution_quality REASONABLE a REASONABLE solution
P(r) peaks n_peaks2
Primary peak position r_peak_primary49.2 Å
Skewness Skewness skewness0.474
Kurtosis Kurtosis kurtosis0.202
Angular range angular_range— – 0.2000 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha162900000.0000
Real-space data points n_real_points41
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.662; Stabil: 1.000; Sysdev: 0.013; Positv: 1.000; Valcen: 0.995; Smooth: 0.913
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (6)

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8. Citations (1)

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9. Files and Curves (10)