8e2k

Cryo-EM structure of BIRC6/HtrA2-S306A

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Baculoviral IAP repeat-containing protein 6

Homo sapiens

UniProt Q9NR09

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Serine protease HTRA2, mitochondrial × 3 (O43464) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BIRC6_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 42–4898; UniProt 1–4857 Author chain B; PDBConstruct 42–4898; UniProt 1–4857

Serine protease HTRA2, mitochondrial

Homo sapiens

UniProt O43464

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Baculoviral IAP repeat-containing protein 6 × 2 (Q9NR09) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name HTRA2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain X; PDBConstruct 2–326; UniProt 134–458 Author chain Y; PDBConstruct 2–326; UniProt 134–458 Author chain Z; PDBConstruct 2–326; UniProt 134–458

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8e2k
Deposition date deposition_date2022-08-15
Structure title titleCryo-EM structure of BIRC6/HtrA2-S306A
Keywords keywordsUbiquitin, E3 ligase, Apoptosis, Autophagy, IAP, LIGASE; LIGASE
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8e2k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8e2k__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8e2k__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)71.43 Å
Rg (electron density)71.55 Å
Total Rg71.69 Å
Atom count96469
Residues6160
Excluded volume860690 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8e2k__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▶

7. Citations (1)