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8ixd

GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Tubulin alpha-1C chain

Mus musculus

UniProt P68373

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 27 Tubulin beta-2A chain × 9 （Q7TMM9） Kinesin-1 heavy chain × 9 （P33176） GUANOSINE-5'-TRIPHOSPHATE × 9 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 9 ADENOSINE-5'-TRIPHOSPHATE × 9 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
12dl 24mc 8ixd 8ixe

4 assemblies

View Construct and Data Evidence
UniProt name TBA1C_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–455； UniProt 1–449 Author chain B； PDBConstruct 1–455； UniProt 1–449 Author chain C； PDBConstruct 1–455； UniProt 1–449 Author chain D； PDBConstruct 1–455； UniProt 1–449 Author chain E； PDBConstruct 1–455； UniProt 1–449 Author chain F； PDBConstruct 1–455； UniProt 1–449 Author chain G； PDBConstruct 1–455； UniProt 1–449 Author chain H； PDBConstruct 1–455； UniProt 1–449 Author chain I； PDBConstruct 1–455； UniProt 1–449

Tubulin beta-2A chain

Mus musculus

UniProt Q7TMM9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 27 Tubulin alpha-1C chain × 9 （P68373） Kinesin-1 heavy chain × 9 （P33176） GUANOSINE-5'-TRIPHOSPHATE × 9 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 9 ADENOSINE-5'-TRIPHOSPHATE × 9 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
24mc 8ixa 8ixb 8ixd 8ixe 8ixf 8ixg 9w2m

8 assemblies

View Construct and Data Evidence
UniProt name TBB2A_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain J； PDBConstruct 1–445； UniProt 1–445 Author chain K； PDBConstruct 1–445； UniProt 1–445 Author chain L； PDBConstruct 1–445； UniProt 1–445 Author chain M； PDBConstruct 1–445； UniProt 1–445 Author chain N； PDBConstruct 1–445； UniProt 1–445 Author chain O； PDBConstruct 1–445； UniProt 1–445 Author chain P； PDBConstruct 1–445； UniProt 1–445 Author chain Q； PDBConstruct 1–445； UniProt 1–445 Author chain R； PDBConstruct 1–445； UniProt 1–445

Kinesin-1 heavy chain

Homo sapiens

UniProt P33176

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 27 Tubulin alpha-1C chain × 9 （P68373） Tubulin beta-2A chain × 9 （Q7TMM9） GUANOSINE-5'-TRIPHOSPHATE × 9 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 9 ADENOSINE-5'-TRIPHOSPHATE × 9 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1bg2 1mkj 5lt3 5lt3 5lt3 5lt3 5lt3 5lt3 5lt4 5lt4 5lt4 5lt4

20 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3j8x 3j8y 4hna 4lnu 6ojq 7tr1 7tr2 8ixa 8ixb 8ixd 8ixe 8ixf

19 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name KINH_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain S； PDBConstruct 24–372； UniProt 1–349 Author chain T； PDBConstruct 24–372； UniProt 1–349 Author chain U； PDBConstruct 24–372； UniProt 1–349 Author chain V； PDBConstruct 24–372； UniProt 1–349 Author chain W； PDBConstruct 24–372； UniProt 1–349 Author chain X； PDBConstruct 24–372； UniProt 1–349 Author chain Y； PDBConstruct 24–372； UniProt 1–349 Author chain Z； PDBConstruct 24–372； UniProt 1–349 Author chain a； PDBConstruct 24–372； UniProt 1–349

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8ixd
Deposition date deposition_date2023-03-31
Structure title titleGMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region
Keywords keywordsmicrotubule, tubulin isotype, cryo-EM structure, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ixd__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ixd__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8ixd__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）87.69 Å
Rg (electron density)87.97 Å
Total Rg87.91 Å
Atom count84096
Residues10602
Excluded volume1484600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8ixd__assembly_1__model_1 27-meric （27） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)