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9mo8

Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free state (upper strand)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Actin, alpha cardiac muscle 1

OrganismNot specified

UniProt P68033

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 15 Troponin C, slow skeletal and cardiac muscles × 1 （P19123） Troponin I, cardiac muscle × 1 （P48787） Isoform A2 of Troponin T, cardiac muscle × 2 （P50752） Tropomyosin alpha-1 chain × 4 （P58771） ADENOSINE-5'-DIPHOSPHATE × 7 MAGNESIUM ION × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
8q4g 8zbk 8zbn 8zip 8ziu 9e2e 9mo4 9mo5 9mo6 9mo7 9mo8 9mo9

26 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ACTC_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–377； UniProt 1–377 Author chain B； PDBConstruct 1–377； UniProt 1–377 Author chain C； PDBConstruct 1–377； UniProt 1–377 Author chain D； PDBConstruct 1–377； UniProt 1–377 Author chain E； PDBConstruct 1–377； UniProt 1–377 Author chain F； PDBConstruct 1–377； UniProt 1–377 Author chain G； PDBConstruct 1–377； UniProt 1–377

Troponin C, slow skeletal and cardiac muscles

OrganismNot specified

UniProt P19123

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 15 Actin, alpha cardiac muscle 1 × 7 （P68033） Troponin I, cardiac muscle × 1 （P48787） Isoform A2 of Troponin T, cardiac muscle × 2 （P50752） Tropomyosin alpha-1 chain × 4 （P58771） ADENOSINE-5'-DIPHOSPHATE × 7 MAGNESIUM ION × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6klt 6klu 9mo4 9mo5 9mo6 9mo7 9mo8 9mo9 9moa 9mob 9moc 9mod

22 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TNNC1_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain H； PDBConstruct 1–161； UniProt 1–161

Troponin I, cardiac muscle

OrganismNot specified

UniProt P48787

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 15 Actin, alpha cardiac muscle 1 × 7 （P68033） Troponin C, slow skeletal and cardiac muscles × 1 （P19123） Isoform A2 of Troponin T, cardiac muscle × 2 （P50752） Tropomyosin alpha-1 chain × 4 （P58771） ADENOSINE-5'-DIPHOSPHATE × 7 MAGNESIUM ION × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2jpw

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6klt 6klu 9mo4 9mo5 9mo6 9mo7 9mo8 9mo9 9moa 9mob 9moc 9mod

22 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TNNI3_MOUSE
Isoform —
PDB entities 3
Chains and sequence ranges Author chain I； PDBConstruct 1–211； UniProt 1–211

Isoform A2 of Troponin T, cardiac muscle

OrganismNot specified

UniProt P50752

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 15 Actin, alpha cardiac muscle 1 × 7 （P68033） Troponin C, slow skeletal and cardiac muscles × 1 （P19123） Troponin I, cardiac muscle × 1 （P48787） Tropomyosin alpha-1 chain × 4 （P58771） ADENOSINE-5'-DIPHOSPHATE × 7 MAGNESIUM ION × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6klt 6klu 9e2e 9mo4 9mo5 9mo6 9mo7 9mo8 9moi 9mok 9mol 9mom

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TNNT2_MOUSE
Isoform P50752-3
PDB entities 4
Chains and sequence ranges Author chain J； PDBConstruct 1–291； UniProt 1–291 Author chain K； PDBConstruct 1–291； UniProt 1–291

Tropomyosin alpha-1 chain

OrganismNot specified

UniProt P58771

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 15 Actin, alpha cardiac muscle 1 × 7 （P68033） Troponin C, slow skeletal and cardiac muscles × 1 （P19123） Troponin I, cardiac muscle × 1 （P48787） Isoform A2 of Troponin T, cardiac muscle × 2 （P50752） ADENOSINE-5'-DIPHOSPHATE × 7 MAGNESIUM ION × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7nep 8q4g 8zbk 8zbn 9e2e 9mo4 9mo5 9mo6 9mo7 9mo8 9mo9 9moa

25 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TPM1_MOUSE
Isoform —
PDB entities 5
Chains and sequence ranges Author chain L； PDBConstruct 1–284； UniProt 1–284 Author chain M； PDBConstruct 1–284； UniProt 1–284 Author chain N； PDBConstruct 1–284； UniProt 1–284 Author chain O； PDBConstruct 1–284； UniProt 1–284

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9mo8
Deposition date deposition_date2024-12-25
Structure title titleStructure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free state (upper strand)
Keywords keywordsthin filament, cryo-EM, troponin, tropomyosin, muscle structure, motor protein; MOTOR PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9mo8__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9mo8__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9mo8__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)109.70 Å
Total Rg109.00 Å
Atom count28893
Residues3630
Excluded volume513090 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9mo8__assembly_1__model_1 pentadecameric （15） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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7. Citations (1)