TRIM21-NUP98 Molecular Glue Complex (MAN-056)

entry_id	9pll
deposition_date	2025-07-15
last_revision	2026-05-27
title	TRIM21-NUP98 Molecular Glue Complex (MAN-056)
keywords	Molecular glue, ubiquitin ligase, targeted protein degradation, nuclear pore, TRIM21, LIGASE; LIGASE
method	X-RAY DIFFRACTION

rg_guinier	23.20 Å
rg_electron	22.32 Å
i0	46822100.00
molecular_weight	35667.0 kDa
excluded_volume	34576 ų
envelope_volume	57577 ų
shell_volume	21957 ų
envelope_diameter	84.3 Å
shell_rg	28.58 Å
envelope_rg	22.63 Å
shape_rg	22.28 Å
total_rg	22.97 Å
total_atoms	2706
n_residues	335
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	81.5 Å
rg_real	23.20 Å
rg_real_error	0.59 Å
i0_real	4.6820e+07
i0_real_error	6.8580e+05
rg_reciprocal	23.20 Å
i0_reciprocal	46820000.0000
total_estimate	0.7879
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	25.1 Å
skewness	0.350
kurtosis	-0.379
angular_range	— – 0.3400 Å−1
current_alpha	0.0000
highest_alpha	6345000.0000
n_real_points	66
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.770; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.928; Smooth: 0.000

Unit Cell

length_a	57.481 Å
length_b	71.307 Å
length_c	97.455 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

Symmetry

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

Refinement

resolution	1.600 Å
resolution_low	49.510 Å
r_factor	—
r_work	0.1748
r_free	0.2137

Diffraction

temperature

99.5 K

Files (7)

• pr_distribution /app/data/pr_computation/pl/9pll/pr_distribution.json
• pr_output /app/data/pr_computation/pl/9pll/9pll.pr.out
• pr_plot /app/data/visualization/pr_computation/pl/9pll/9pll_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/pl/9pll/9pll.dat
• saxs_fit /app/data/saxs_computation/pl/9pll/9pll.fit
• saxs_log /app/data/saxs_computation/pl/9pll/9pll.log
• saxs_plot /app/data/visualization/saxs_computation/pl/9pll/9pll_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/pl/9pll/9pll.fit
pddf	/app/data/pr_computation/pl/9pll/9pll.pr.out
profile	/app/data/saxs_computation/pl/9pll/9pll.dat