5a9q

Human nuclear pore complex

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

NUCLEOPORIN NUP43

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NUP43_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 0； PDBConstruct 1–380； UniProt 1–380 Author chain 9； PDBConstruct 1–380； UniProt 1–380 Author chain I； PDBConstruct 1–380； UniProt 1–380 Author chain R； PDBConstruct 1–380； UniProt 1–380

NUCLEAR PORE COMPLEX PROTEIN NUP160

OrganismNot specified

UniProt Q12769

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NU160_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 1； PDBConstruct 1–1436； UniProt 1–1436 Author chain J； PDBConstruct 1–1436； UniProt 1–1436 Author chain S； PDBConstruct 1–1436； UniProt 1–1436 Author chain a； PDBConstruct 1–1436； UniProt 1–1436

NUCLEOPORIN NUP37

OrganismNot specified

UniProt Q8NFH4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NUP37_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain 2； PDBConstruct 1–326； UniProt 1–326 Author chain K； PDBConstruct 1–326； UniProt 1–326 Author chain T； PDBConstruct 1–326； UniProt 1–326 Author chain b； PDBConstruct 1–326； UniProt 1–326

NUCLEAR PORE COMPLEX PROTEIN NUP133

OrganismNot specified

UniProt Q8WUM0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NU133_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 3； PDBConstruct 1–1156； UniProt 1–1156 Author chain C； PDBConstruct 1–1156； UniProt 1–1156 Author chain L； PDBConstruct 1–1156； UniProt 1–1156 Author chain U； PDBConstruct 1–1156； UniProt 1–1156

NUCLEAR PORE COMPLEX PROTEIN NUP107

OrganismNot specified

UniProt P57740

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NU107_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain 4； PDBConstruct 1–925； UniProt 1–925 Author chain D； PDBConstruct 1–925； UniProt 1–925 Author chain M； PDBConstruct 1–925； UniProt 1–925 Author chain V； PDBConstruct 1–925； UniProt 1–925

NUCLEAR PORE COMPLEX PROTEIN NUP96

OrganismNot specified

UniProt P52948

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NUP98_HUMAN
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain 5； PDBConstruct 1–937； UniProt 881–1817 Author chain E； PDBConstruct 1–937； UniProt 881–1817 Author chain N； PDBConstruct 1–937； UniProt 881–1817 Author chain W； PDBConstruct 1–937； UniProt 881–1817

PROTEIN SEC13 HOMOLOG

OrganismNot specified

UniProt P55735

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SEC13_HUMAN
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain 6； PDBConstruct 1–322； UniProt 1–322 Author chain F； PDBConstruct 1–322； UniProt 1–322 Author chain O； PDBConstruct 1–322； UniProt 1–322 Author chain X； PDBConstruct 1–322； UniProt 1–322

NUCLEOPORIN SEH1

OrganismNot specified

UniProt Q96EE3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SEH1_HUMAN
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain 7； PDBConstruct 1–360； UniProt 1–360 Author chain G； PDBConstruct 1–360； UniProt 1–360 Author chain P； PDBConstruct 1–360； UniProt 1–360 Author chain Y； PDBConstruct 1–360； UniProt 1–360

NUCLEAR PORE COMPLEX PROTEIN NUP85

OrganismNot specified

UniProt Q9BW27

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP155 × 16 （O75694）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NUP85_HUMAN
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain 8； PDBConstruct 1–656； UniProt 1–656 Author chain H； PDBConstruct 1–656； UniProt 1–656 Author chain Q； PDBConstruct 1–656； UniProt 1–656 Author chain Z； PDBConstruct 1–656； UniProt 1–656

NUCLEAR PORE COMPLEX PROTEIN NUP155

OrganismNot specified

UniProt O75694

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 304	NUCLEOPORIN NUP43 × 32 （Q8NFH3） NUCLEAR PORE COMPLEX PROTEIN NUP160 × 32 （Q12769） NUCLEOPORIN NUP37 × 32 （Q8NFH4） NUCLEAR PORE COMPLEX PROTEIN NUP133 × 32 （Q8WUM0） NUCLEAR PORE COMPLEX PROTEIN NUP107 × 32 （P57740） NUCLEAR PORE COMPLEX PROTEIN NUP96 × 32 （P52948） PROTEIN SEC13 HOMOLOG × 32 （P55735） NUCLEOPORIN SEH1 × 32 （Q96EE3） NUCLEAR PORE COMPLEX PROTEIN NUP85 × 32 （Q9BW27）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NU155_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain A； PDBConstruct 1–1391； UniProt 1–1391 Author chain B； PDBConstruct 1–1391； UniProt 1–1391

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	5a9q
Deposition date deposition_date	2015-07-22
Structure title title	Human nuclear pore complex
Keywords keywords	TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5a9q__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5a9q__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

5a9q__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	552.20 Å
Total Rg	552.20 Å
Atom count	767072
Residues	154800
Excluded volume	12375000 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`5a9q__assembly_1__model_1`	304-meric （304）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (10)

Entity 1 Entity 1 polymer

Description description	NUCLEOPORIN NUP43
Molecular weight formula_weight	42195.7 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	0,9,I,R
Atom count atom_count	95884

MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHYHTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLGPCLVCGTDAEAIYVTRHLFS

Entity 2 Entity 2 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP160
Molecular weight formula_weight	162280.2 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	1,J,S,a

MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERNLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL

Entity 3 Entity 3 polymer

Description description	NUCLEOPORIN NUP37
Molecular weight formula_weight	36748.5 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2,K,T,b

MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGTCTFQEEEADVEGIQYKTLRTFHHGVRVDGIAWSPETRLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNLEGVQTAHFVLHSPGMSVCWHPEETFKLMVAEKNGTIRFYDLLAQQAILSLESEQVPLMSAHWCLKNTFKVGAVAGNDWLIWDITRSSYPQNKRPVHMDRACLFRWSTISENLFATTGYPGKMASQFQIHHLGHPQPILMGSVAVGSGLSWHRTLPLCVIGGDHKLLFWVTEV

Entity 4 Entity 4 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP133
Molecular weight formula_weight	129108.5 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3,C,L,U

MFPAAPSPRTPGTGSRRGPLAGLGPGSTPRTASRKGLPLGSAVSSPVLFSPVGRRSSLSSRGTPTRMFPHHSITESVNYDVKTFGSSLPVKVMEALTLAEVDDQLTINIDEGGWACLVCKEKLIIWKIALSPITKLSVCKELQLPPSDFHWSADLVALSYSSPSGEAHSTQAVAVMVATREGSIRYWPSLAGEDTYTEAFVDSGGDKTYSFLTAVQGGSFILSSSGSQLIRLIPESSGKIHQHILPQGQGMLSGIGRKVSSLFGILSPSSDLTLSSVLWDRERSSFYSLTSSNISKWELDDSSEKHAYSWDINRALKENITDAIWGSESNYEAIKEGVNIRYLDLKQNCDGLVILAAAWHSADNPCLIYYSLITIEDNGCQMSDAVTVEVTQYNPPFQSEDLILCQLTVPNFSNQTAYLYNESAVYVCSTGTGKFSLPQEKIVFNAQGDSVLGAGACGGVPIIFSRNSGLVSITSRENVSILAEDLEGSLASSVAGPNSESMIFETTTKNETIAQEDKIKLLKAAFLQYCRKDLGHAQMVVDELFSSHSDLDSDSELDRAVTQISVDLMDDYPASDPRWAESVPEEAPGFSNTSLIILHQLEDKMKAHSFLMDFIHQVGLFGRLGSFPVRGTPMATRLLLCEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPSNLTPADVFFREVSQVDTICECLLEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRREESLEKEPEYVPWTATSGPGGIRTVIIRQHEIVLKVAYPQADSNLRNIVTEQLVALIDCFLDGYVSQLKSVDKSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYLWAASLAEKYCDFDILVQMCEQTDNQSRLQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQAHEHLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALASDFSEDMLQEKIEEMAEQERFLLHQETLPEQLLAEKQLNLSAMPVLTAPQLIGLYICEENRRANEYDFKKALDLLEYIDEEEDININDLKLEILCKALQRDNWSSSDGKDDPIEVSKDSIFVKILQKLLKDGIQLSEYLPEVKDLLQADQLGSLKSNPYFEFVLKANYEYYVQGQI

Entity 5 Entity 5 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP107
Molecular weight formula_weight	106505.0 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4,D,M,V

MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL

Entity 6 Entity 6 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP96
Molecular weight formula_weight	106039.7 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	5,E,N,W

SKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSASTHIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASHSSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTMPSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSGEQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQTPLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCEALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTSDSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL

Entity 7 Entity 7 polymer

Description description	PROTEIN SEC13 HOMOLOG
Molecular weight formula_weight	35578.4 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	6,F,O,X

MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ

Entity 8 Entity 8 polymer

Description description	NUCLEOPORIN SEH1
Molecular weight formula_weight	39700.6 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	7,G,P,Y

MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGGPTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKCTGILKGNGSPVNGSSQQGTSNPSLGSTIPSLQNSLNGSSAGRKHS

Entity 9 Entity 9 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP85
Molecular weight formula_weight	75105.3 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	8,H,Q,Z

MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVAIAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS

Entity 10 Entity 10 polymer

Description description	NUCLEAR PORE COMPLEX PROTEIN NUP155
Molecular weight formula_weight	155357.3 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B

MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	1

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	23.000 Å
Low-resolution limit resolution_low	— Å
R factor r_factor	—
R_work r_work	—
R_free r_free	—

Resolution resolution	23.00 Å
Resolution测定Method resolution_method	SUBTOMOGRAM AVERAGING
颗粒数 num_particles	—

Human nuclear pore complex

1. Protein Identity and Related Structures Protein Identity & Related Structures

NUCLEOPORIN NUP43

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP160

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEOPORIN NUP37

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP133

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP107

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP96

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

PROTEIN SEC13 HOMOLOG

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEOPORIN SEH1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP85

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

NUCLEAR PORE COMPLEX PROTEIN NUP155

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer