5ijn

Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

NUCLEAR PORE COMPLEX PROTEIN NUP155

Homo sapiens

UniProt O75694

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP93 × 32 (Q8N1F7) NUCLEAR PORE COMPLEX PROTEIN NUP205 × 32 (Q92621) NUCLEAR PORE COMPLEX PROTEIN NUP54 × 32 (Q7Z3B4) NUCLEAR PORE COMPLEX PROTEIN NUP58 × 32 (Q9BVL2) Nuclear pore glycoprotein p62 × 32 (P37198) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU155_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–1391; UniProt 1–1391 Author chain B; PDBConstruct 1–1391; UniProt 1–1391 Author chain E; PDBConstruct 1–1391; UniProt 1–1391 Author chain K; PDBConstruct 1–1391; UniProt 1–1391 Author chain Q; PDBConstruct 1–1391; UniProt 1–1391 Author chain W; PDBConstruct 1–1391; UniProt 1–1391

NUCLEAR PORE COMPLEX PROTEIN NUP93

Homo sapiens

UniProt Q8N1F7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP155 × 48 (O75694) NUCLEAR PORE COMPLEX PROTEIN NUP205 × 32 (Q92621) NUCLEAR PORE COMPLEX PROTEIN NUP54 × 32 (Q7Z3B4) NUCLEAR PORE COMPLEX PROTEIN NUP58 × 32 (Q9BVL2) Nuclear pore glycoprotein p62 × 32 (P37198) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP93_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C; PDBConstruct 1–819; UniProt 1–819 Author chain I; PDBConstruct 1–819; UniProt 1–819 Author chain O; PDBConstruct 1–819; UniProt 1–819 Author chain U; PDBConstruct 1–819; UniProt 1–819

NUCLEAR PORE COMPLEX PROTEIN NUP205

Homo sapiens

UniProt Q92621

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP155 × 48 (O75694) NUCLEAR PORE COMPLEX PROTEIN NUP93 × 32 (Q8N1F7) NUCLEAR PORE COMPLEX PROTEIN NUP54 × 32 (Q7Z3B4) NUCLEAR PORE COMPLEX PROTEIN NUP58 × 32 (Q9BVL2) Nuclear pore glycoprotein p62 × 32 (P37198) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NU205_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain D; PDBConstruct 1–2012; UniProt 1–2012 Author chain J; PDBConstruct 1–2012; UniProt 1–2012 Author chain P; PDBConstruct 1–2012; UniProt 1–2012 Author chain V; PDBConstruct 1–2012; UniProt 1–2012

NUCLEAR PORE COMPLEX PROTEIN NUP54

Homo sapiens

UniProt Q7Z3B4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP155 × 48 (O75694) NUCLEAR PORE COMPLEX PROTEIN NUP93 × 32 (Q8N1F7) NUCLEAR PORE COMPLEX PROTEIN NUP205 × 32 (Q92621) NUCLEAR PORE COMPLEX PROTEIN NUP58 × 32 (Q9BVL2) Nuclear pore glycoprotein p62 × 32 (P37198) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP54_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain F; PDBConstruct 1–507; UniProt 1–507 Author chain L; PDBConstruct 1–507; UniProt 1–507 Author chain R; PDBConstruct 1–507; UniProt 1–507 Author chain X; PDBConstruct 1–507; UniProt 1–507

NUCLEAR PORE COMPLEX PROTEIN NUP58

Homo sapiens

UniProt Q9BVL2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP155 × 48 (O75694) NUCLEAR PORE COMPLEX PROTEIN NUP93 × 32 (Q8N1F7) NUCLEAR PORE COMPLEX PROTEIN NUP205 × 32 (Q92621) NUCLEAR PORE COMPLEX PROTEIN NUP54 × 32 (Q7Z3B4) Nuclear pore glycoprotein p62 × 32 (P37198) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP58_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain G; PDBConstruct 1–599; UniProt 1–599 Author chain M; PDBConstruct 1–599; UniProt 1–599 Author chain S; PDBConstruct 1–599; UniProt 1–599 Author chain Y; PDBConstruct 1–599; UniProt 1–599

Nuclear pore glycoprotein p62

Homo sapiens

UniProt P37198

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 208 NUCLEAR PORE COMPLEX PROTEIN NUP155 × 48 (O75694) NUCLEAR PORE COMPLEX PROTEIN NUP93 × 32 (Q8N1F7) NUCLEAR PORE COMPLEX PROTEIN NUP205 × 32 (Q92621) NUCLEAR PORE COMPLEX PROTEIN NUP54 × 32 (Q7Z3B4) NUCLEAR PORE COMPLEX PROTEIN NUP58 × 32 (Q9BVL2) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NUP62_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain H; PDBConstruct 1–522; UniProt 1–522 Author chain N; PDBConstruct 1–522; UniProt 1–522 Author chain T; PDBConstruct 1–522; UniProt 1–522 Author chain Z; PDBConstruct 1–522; UniProt 1–522

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5ijn
Deposition date deposition_date2016-03-02
Structure title titleComposite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205)
Keywords keywordsNuclear pore complex, Nucleocytoplasmic transport, Transport protein; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5ijn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5ijn__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5ijn__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)329.20 Å
Total Rg329.20 Å
Atom count594304
Residues119904
Excluded volume9592000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5ijn__assembly_1__model_1 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 5ijn__assembly_1__model_2 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 5ijn__assembly_1__model_3 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 5ijn__assembly_1__model_4 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 5ijn__assembly_1__model_5 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 5ijn__assembly_1__model_6 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 5ijn__assembly_1__model_7 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 5ijn__assembly_1__model_8 208-meric (208) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)