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9s9n

Crystal structure of p53 cancer mutant Y220C in complex with rezatapopt analog 8

Method: X-RAY DIFFRACTION Dmax: 75.2 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9s9n

P(r) Distribution

P(r) distribution for 9s9n

1. Structure Basics

entry_id9s9n
deposition_date2025-08-06
titleCrystal structure of p53 cancer mutant Y220C in complex with rezatapopt analog 8
keywordsp53, tumor suppressor, protein stability, protein unfolding disease, small-molecule stabilizer, TRANSCRIPTION; TRANSCRIPTION
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier24.25
rg_electron23.50
i069778900.00
molecular_weight42097.0 kDa
excluded_volume39744 ų
envelope_volume68756 ų
shell_volume24387 ų
envelope_diameter77.2
shell_rg30.47
envelope_rg23.39
shape_rg23.49
total_rg24.09
total_atoms3146
n_residues394
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax75.2
rg_real24.17
rg_real_error0.48
i0_real6.9780e+07
i0_real_error9.1140e+05
rg_reciprocal24.19
i0_reciprocal69780000.0000
total_estimate0.9137
solution_quality EXCELLENT a EXCELLENT solution
n_peaks2
r_peak_primary28.6
skewness0.198
kurtosis-0.587
angular_range— – 0.3250 −1
current_alpha0.0000
highest_alpha5629000.0000
n_real_points64
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.964; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.996; Smooth: 0.987

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)