SAXSdb — 9vei

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1. Structure Basics

entry_id	9vei
deposition_date	2025-06-09
title	structure of human KCNQ1-KCNE1-CaM complex with PIP2
keywords	potassium channel complex, membrane protein; MEMBRANE PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	44.14 Å
rg_electron	43.54 Å
i0	764590000.00
molecular_weight	225520.0 kDa
excluded_volume	281040 Å³
envelope_volume	426050 Å³
shell_volume	80368 Å³
envelope_diameter	152.6 Å
shell_rg	49.93 Å
envelope_rg	42.90 Å
shape_rg	43.56 Å
total_rg	43.81 Å
total_atoms	15940
n_residues	2200
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	145.8 Å
rg_real	43.99 Å
rg_real_error	1.03 Å
i0_real	7.6460e+08
i0_real_error	1.2430e+07
rg_reciprocal	44.14 Å
i0_reciprocal	764700000.0000
total_estimate	0.8590
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	56.7 Å
skewness	0.300
kurtosis	-0.032
angular_range	— – 0.1800 Å⁻¹
current_alpha	0.0000
highest_alpha	81190000.0000
n_real_points	37
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.780; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.978; Smooth: 0.843

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	Potassium voltage-gated channel subfamily KQT member 1
formula_weight	62076.3 kDa
mutation	I145C
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	A,D,G,J
atom_count	15940

MASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTCEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLH

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	Calmodulin-1
formula_weight	16852.5 kDa
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	B,E,H,K

MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 3 polymer

description	Potassium voltage-gated channel subfamily E member 1
formula_weight	14664.7 kDa
mutation	K41C
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	C,L,F,I

MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGCLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo

Entity 4 non-polymer

description	;[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate ;
formula_weight	1047.1 kDa
src_method	syn
entity_count	8

Entity 5 non-polymer

description	CALCIUM ION
formula_weight	40.1 kDa
src_method	syn
entity_count	8

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.90 Å
resolution_method	—
num_particles	110909

fit	/app/data/saxs_computation/ve/9vei/9vei.fit
pddf	/app/data/pr_computation/ve/9vei/9vei.pr.out
profile	/app/data/saxs_computation/ve/9vei/9vei.dat

structure of human KCNQ1-KCNE1-CaM complex with PIP2

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 non-polymer

Entity 5 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)